Our custom-compounded Epinephrine 0.02%/Lidocaine HCl 2%/Tetracaine 2% Topical Gel is a specialized medication designed for precise and targeted application on the skin. This semisolid formulation is dispensed through a pump mechanism, which ensures ease of use and accurate dosing. The gel base provides a suitable medium for the active ingredients to be applied topically, offering a localized effect with minimal systemic absorption.

The combination of active ingredients in this formulation serves multiple therapeutic purposes. Epinephrine, a potent vasoconstrictor, helps to reduce local blood flow and swelling, and can prolong the duration of action of local anesthetics. Lidocaine HCl and Tetracaine are both local anesthetics that work by blocking nerve signals in the body. Lidocaine HCl is known for its rapid onset of action and intermediate duration, while Tetracaine is characterized by a longer onset and duration of action. Together, these anesthetics provide a synergistic effect for prolonged numbing and pain relief.

This topical gel is particularly useful in minor surgical procedures, dermatological interventions, and as a pre-treatment anesthetic for needle insertion or other invasive skin procedures. It can also be beneficial in managing chronic pain conditions where localized topical therapy is indicated. The formulation's vasoconstrictive properties may reduce bleeding in the application area, which is advantageous during minor surgical procedures.

Patients should be advised that the use of this gel should be limited to the prescribed area and duration to minimize the risk of systemic absorption and potential side effects. Prescribers should consider the patient's medical history, including any known allergies to local anesthetics or sympathomimetic amines, before recommending this formulation. It is also important to instruct patients on the proper application technique to ensure safety and efficacy.

For any questions or additional information regarding this custom-compounded medication, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive support and guidance to both patients and healthcare providers.

The topical gel formulation containing Epinephrine 0.02%, Lidocaine HCl 2%, and Tetracaine 2% is designed for localized application and is intended to provide local anesthesia and vasoconstriction. While the systemic absorption of these agents is generally low when applied topically, there is still potential for drug interactions, particularly if the gel is applied to large areas, used over prolonged periods, or applied to broken or inflamed skin, which may increase systemic absorption.

Epinephrine is a sympathomimetic agent that can interact with several classes of medications. It should be used with caution in patients taking monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, or certain antihistamines, as these drugs can potentiate the effects of epinephrine, leading to increased blood pressure and heart rate. Beta-blockers may also interact with epinephrine, potentially leading to hypertension and bradycardia. Patients with cardiovascular diseases or those taking cardiac glycosides should be monitored closely, as epinephrine can affect heart rhythm and contractility.

Lidocaine and Tetracaine are both local anesthetics that can cause additive systemic effects if used with other local anesthetics or agents that affect cardiac conduction. Caution is advised when using this gel in conjunction with other medications that can cause methemoglobinemia, such as sulfonamides, acetaminophen, and nitrates. Additionally, the use of other CNS depressants, such as opioids or sedatives, may increase the risk of CNS side effects when combined with local anesthetics, although this is less likely with topical administration.

Patients should be advised to inform their healthcare provider of all medications they are taking, including prescription drugs, over-the-counter medications, and herbal supplements, to assess for potential drug interactions. It is also important to follow the prescribed dosing and application instructions to minimize the risk of systemic absorption and potential drug interactions.

This topical gel is used for the treatment of conditions that require local anesthesia, such as minor surgical procedures, wound care, or other situations where pain relief and vasoconstriction are desired. The combination of epinephrine with lidocaine and tetracaine provides both a numbing effect and a reduction in local blood flow, which can help to control bleeding and prolong the duration of anesthesia.

If you have any questions or require further information regarding this formulation and its potential drug interactions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this medication.

The Epinephrine 0.02%/Lidocaine HCl 2%/Tetracaine 2% Topical Gel is a compounded medication designed to provide localized action with a combination of active ingredients, each serving a specific therapeutic purpose. The gel is formulated to be applied topically, where it exerts its effects directly on the site of application, minimizing systemic absorption and potential side effects.

Epinephrine, also known as adrenaline, is a vasoconstrictor that works by narrowing blood vessels. In this topical formulation, the low concentration of 0.02% helps to reduce local blood flow, which can decrease swelling and bleeding. This is particularly useful in conditions where minimizing bleeding is essential, such as during minor surgical procedures or to control superficial bleeding on the skin.

Lidocaine HCl and Tetracaine are both local anesthetics that work by blocking sodium channels, which are necessary for the initiation and conduction of nerve impulses. When applied to the skin, these anesthetics provide a numbing effect, leading to temporary loss of sensation in the area of application. Lidocaine HCl 2% and Tetracaine 2% work synergistically to provide a more profound and longer-lasting anesthetic effect than either would alone. This combination is particularly useful for procedures that require local anesthesia or for providing relief from pain due to conditions like minor burns, insect bites, or other localized skin irritations.

The gel formulation is designed to be dispensed through a pump mechanism, which allows for easy and precise dosing. The semisolid consistency of the gel ensures that it stays in place upon application, providing targeted treatment and facilitating the absorption of the active ingredients. The gel base also has a soothing effect on the skin, which can enhance patient comfort during application.

This compounded medication is intended for use under the guidance of a healthcare professional. It is important to apply the gel as directed, typically to intact skin, and to avoid contact with eyes or mucous membranes. Patients should be advised that the area of application may be numb for some time after use and to protect it from injury until sensation returns.

For prescribers considering this formulation for their patients, it is essential to assess the patient's medical history, current medications, and potential for allergic reactions to any of the components. The unique combination of epinephrine, lidocaine, and tetracaine in a topical gel form offers a versatile option for managing pain and controlling bleeding in localized areas.

If you have any questions about this formulation or its appropriate use, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide the necessary information and support to ensure the safe and effective use of this medication.

The formulation of Epinephrine 0.02%/Lidocaine HCl 2%/Tetracaine 2% Topical Gel is primarily designed to deliver local anesthesia and prolong its effect, while also providing a vasoconstrictive property due to epinephrine. Traditionally, this combination is used to numb a specific area of the skin for minor surgical procedures, dermatological interventions, and pain relief from conditions such as postherpetic neuralgia. However, its use may extend beyond these applications. The inclusion of epinephrine not only prolongs the action of the local anesthetics but can also reduce bleeding due to its vasoconstricting effect. This can potentially make the formulation beneficial in managing superficial wounds, where reduced bleeding and pain control are desirable.

Another possible use of this gel could be in the control of chronic pain conditions, such as certain neuropathic pain syndromes, where the application of topical anesthetics can provide localized pain relief without systemic side effects. Additionally, for patients undergoing superficial cosmetic procedures, such as micro-needling or laser therapy, the formulation may serve to reduce discomfort during the procedure.

Due to the vasopressor action of epinephrine, the formulation might be used off-label for pressure ulcers or chronic wounds, with the idea being that improved local blood flow could potentially aid in healing. However, such uses would need careful consideration due to the risk of local tissue necrosis with excessive vasoconstriction. It is essential also to note that use in larger areas or over broken skin may increase the risk of systemic absorption and related side effects.

Patients and prescribers should be cautious and ensure that the formulation is appropriate for use outside of the traditional indications. Factors such as patient-specific contraindications, the extent of the area being treated, and the integrity of the skin barrier need to be considered. Moreover, this product should not be used in individuals with a known hypersensitivity to any of its components or in conditions where vasoconstriction could be detrimental.

As with any medication, the potential for adverse effects or interactions with other drugs should be assessed. The pharmacists at Bayview Pharmacy are committed to ensuring safe and effective use of this formulation and welcome any inquiries from both patients and healthcare professionals regarding its use. If there are any questions about the potential other uses of Epinephrine 0.02%/Lidocaine HCl 2%/Tetracaine 2% Topical Gel or if there is a need for compounded alternatives tailored to individual patient's needs, please do not hesitate to reach out to us.