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Enalapril Maleate 5 mg/5 mL Oral Liquid

Description: Enalapril Maleate 5 mg/5 mL Oral Liquid is a specifically formulated medication designed for oral administration. This liquid formulation offers a convenient and easily ingested alternative to solid dosage forms, ensuring accurate medication delivery. It is particularly beneficial for patients who experience difficulty swallowing pills, including pediatric and geriatric populations. Enalapril Maleate is an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension (high blood pressure) and heart failure. By relaxing blood vessels, it helps to lower blood pressure and improve the efficiency of the heart. This medication can also be used to prevent symptomatic heart failure and to reduce the risk of hospitalization for patients with left ventricular dysfunction.

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Oral Liquid
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Formula Information

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Enalapril Maleate 5 mg/5 mL Oral Liquid is a specially compounded medication designed for ease of administration and precise dosing. This formulation is particularly beneficial for patients who have difficulty swallowing tablets or capsules, such as young children, the elderly, or those with dysphagia. The liquid form allows for flexible dosing, which can be adjusted according to the specific needs of the patient.

Enalapril is an angiotensin-converting enzyme (ACE) inhibitor, which works by relaxing blood vessels, thereby lowering blood pressure and improving blood flow. This mechanism makes it an effective treatment for hypertension (high blood pressure) and heart failure. By managing blood pressure, enalapril helps to prevent strokes, heart attacks, and kidney problems. It is also used to improve survival after a heart attack and to prevent the progression of heart failure in patients with left ventricular dysfunction.

For patients and prescribers considering Enalapril Maleate 5 mg/5 mL Oral Liquid, it is important to note that the medication should be taken consistently to ensure optimal control of blood pressure. Regular monitoring of blood pressure and kidney function is recommended while on this medication. As with any medication, there may be potential side effects, and it is important to discuss these with a healthcare provider. These can include dizziness, light-headedness, or dry cough. Patients should also be aware of the signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or trouble breathing.

Our team at Bayview Pharmacy is committed to providing high-quality, personalized medication solutions. We are available to answer any questions or concerns you may have about the Enalapril Maleate 5 mg/5 mL Oral Liquid formulation. Our goal is to ensure that both patients and prescribers have the necessary information for safe and effective treatment. Please do not hesitate to reach out to us for further assistance.

Drug Interactions

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Enalapril Maleate is an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and heart failure. When considering the use of Enalapril Maleate 5 mg/5 mL Oral Liquid, it is important to be aware of potential drug interactions that may affect the efficacy of the medication or increase the risk of adverse effects. Patients should be advised to inform their healthcare provider of all medications, supplements, and herbal products they are currently taking before starting treatment with Enalapril Maleate.

One significant interaction is with potassium-sparing diuretics or potassium supplements, which can lead to an increased risk of hyperkalemia (high potassium levels in the blood). This is because ACE inhibitors can increase potassium retention. Similarly, salt substitutes containing potassium should be used cautiously. Nonsteroidal anti-inflammatory drugs (NSAIDs), including over-the-counter options like ibuprofen, may reduce the antihypertensive effects of Enalapril and increase the risk of renal impairment, especially in patients with pre-existing kidney dysfunction.

Concomitant use of Enalapril with other antihypertensive agents, such as diuretics or beta-blockers, may lead to an additive hypotensive effect, which could result in symptomatic hypotension. Patients should be monitored closely when any adjustments to these medications are made. Additionally, Enalapril can enhance the hypoglycemic effects of insulin and oral antidiabetic agents, necessitating close monitoring of blood glucose levels in diabetic patients.

Angiotensin II receptor blockers (ARBs) and direct renin inhibitors should be avoided in combination with Enalapril due to the risk of worsening renal function, hyperkalemia, and hypotension. The use of Enalapril with lithium can lead to increased lithium levels and toxicity; frequent monitoring of serum lithium levels is recommended. Allopurinol, procainamide, and other medications that may lead to leukopenia/neutropenia increase the risk of neutropenia when used with Enalapril, particularly in patients with renal impairment or collagen vascular disease.

Enalapril may also interact with gold injections, which are sometimes used to treat arthritis, leading to symptoms such as facial flushing, nausea, vomiting, and hypotension. Patients receiving mTOR inhibitors (e.g., sirolimus, everolimus, temsirolimus) therapy may be at increased risk for angioedema.

It is essential for patients to maintain consistent communication with their healthcare providers and report any unusual symptoms or side effects. Regular monitoring of blood pressure, renal function, and electrolytes is recommended to ensure safe and effective use of Enalapril Maleate Oral Liquid. If you have any questions or require further information regarding drug interactions with Enalapril Maleate, please reach out to us at Bayview Pharmacy for assistance.

How Does it Work

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Enalapril Maleate is an angiotensin-converting enzyme (ACE) inhibitor, which is a type of medication commonly used to treat high blood pressure (hypertension) and heart failure. The way Enalapril works is by inhibiting the action of the ACE, an enzyme responsible for the production of angiotensin II. Angiotensin II is a potent vasoconstrictor, which means it narrows the blood vessels, increasing blood pressure. By blocking the formation of angiotensin II, Enalapril causes the blood vessels to relax and widen, resulting in a decrease in blood pressure. This reduction in blood pressure means that the heart doesn't have to work as hard to pump blood throughout the body, which is particularly beneficial in patients with heart failure, where the heart's ability to pump blood is compromised.

The Enalapril Maleate 5 mg/5 mL Oral Liquid formulation is designed to provide a precise dose of medication in a form that is easy to ingest. This is especially useful for patients who have difficulty swallowing pills, such as young children or elderly individuals. The liquid form allows for flexible dosing, which can be adjusted according to the specific needs of the patient. The medication can be measured with a syringe, dropper, or measuring spoon, ensuring that the patient receives the correct dose each time.

When using this formulation, it is important to shake the bottle well before each use to ensure that the medication is evenly distributed throughout the liquid. The patient should take the medication as prescribed by their healthcare provider, and it is essential to use it consistently to maintain control over blood pressure or heart failure symptoms. It is also important to monitor blood pressure regularly to ensure that the medication is having the desired effect.

Patients should be aware that Enalapril can cause side effects such as cough, dizziness, or lightheadedness, especially during the first few days of treatment as the body adjusts to the medication. If any severe side effects or signs of an allergic reaction occur, they should seek medical attention immediately. Additionally, patients should inform their healthcare provider of all medications they are taking, as Enalapril can interact with other drugs, potentially leading to adverse effects.

For prescribers considering this formulation for their patients, it is important to consider the patient's medical history, other medications, and the potential for drug interactions. Regular monitoring of the patient's blood pressure and kidney function is recommended to ensure the safety and efficacy of the treatment. Adjustments to the dosage may be necessary based on the patient's response to the medication and any side effects experienced.

If you have any questions about the Enalapril Maleate 5 mg/5 mL Oral Liquid formulation or its use in treating hypertension and heart failure, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to ensure the best possible outcomes for your patients.

Other Uses

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Enalapril Maleate is an angiotensin-converting enzyme (ACE) inhibitor primarily employed in the management of hypertension and some types of chronic heart failure. Beyond these indications, the medication has shown usefulness in other clinical scenarios, although these may not be as well-established and should always be utilized following a thorough evaluation by a healthcare provider. In certain cases, Enalapril Maleate can be used off-label for the management of left ventricular dysfunction and can potentially reduce the progression of renal disease in patients with diabetes who have proteinuria. This is due to its effects on the renin-angiotensin-aldosterone system, which plays a role in hemodynamic regulation and kidney function.

Furthermore, in pediatric patients, Enalapril Maleate liquid form may be used in conditions where ACE inhibitors are indicated and when solid dosage forms are impractical or impossible. In cases of pediatric heart failure or hypertension, where dosing needs to be carefully calculated and individualized based on the child's weight or body surface area, using a liquid dosage form allows for the precise dosing adjustments that are often necessary. Additionally, adults who have difficulty swallowing pills, including those with neurological disorders like Parkinson's disease, or conditions that affect the esophagus, may benefit from the liquid form of Enalapril.

While the liquid form of Enalapril can contribute to improved compliance and ease of administration, it is important to note that the stability of the medication can be influenced by factors related to the compounding process such as pH and temperature, which underscores the importance of obtaining this medication from a reliable compounding pharmacy like Bayview Pharmacy. As with any medication, Enalapril Maleate should be used under the supervision of a healthcare provider, and patients and prescribers are encouraged to communicate openly about the potential risks and benefits, as well as any off-label uses. If you have any questions about the other uses of our Enalapril Maleate 5 mg/5 mL Oral Liquid or how it might fit into your or your patient's therapeutic regimen, please do not hesitate to reach out to us at Bayview Pharmacy for further information and consultation.

Frequently Asked Questions

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What is Enalapril Maleate 5 mg/5 mL Oral Liquid used for?

Enalapril Maleate 5 mg/5 mL Oral Liquid is used to treat high blood pressure (hypertension) and heart failure. It helps to relax blood vessels and improve blood flow, reducing the heart's workload and helping to lower blood pressure.

How should Enalapril Maleate Oral Liquid be taken?

This medication should be taken according to the prescribed dosage by your doctor, usually once or twice daily. Measure the dose carefully with a medical-grade measuring device or spoon, not a household spoon, to ensure you get the correct amount. It can be taken with or without food.

Is Enalapril Maleate Oral Liquid suitable for children?

Yes, Enalapril Maleate Oral Liquid is often prescribed for children who have difficulty swallowing pills or need a precisely measured dose that cannot be achieved with solid dosage forms. Always consult a pediatrician or healthcare provider before administering this medication to a child.

Can geriatric patients use Enalapril Maleate Oral Liquid?

Yes, geriatric patients may find liquid formulations easier to swallow than pills or tablets. The dosage may be adjusted by their healthcare provider based on their specific health profile and needs.

What should I do if I miss a dose of Enalapril Maleate Oral Liquid?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Are there any dietary restrictions while taking Enalapril Maleate Oral Liquid?

While taking Enalapril, it is generally recommended to avoid potassium supplements or salt substitutes containing potassium without your doctor's advice, as this medication can increase potassium levels. Discuss any dietary concerns with your healthcare provider.

What are the potential side effects of Enalapril Maleate Oral Liquid?

Possible side effects of Enalapril Maleate include cough, dizziness, headache, fatigue, and nausea. If you experience any severe side effects, such as difficulty breathing, swelling of the face, lips, or throat, or a significant drop in blood pressure, seek medical attention immediately.

How should I store Enalapril Maleate Oral Liquid?

Store the medication at room temperature, away from light and moisture. Do not store it in the bathroom, and keep the bottle tightly closed when not in use. Be sure to discard any unused medication after the expiration date or as directed by your pharmacist.

Can Enalapril Maleate Oral Liquid be mixed with other liquids?

It is not recommended to mix the medication with other liquids unless instructed by your healthcare provider. If swallowing the liquid is difficult, ask your doctor or pharmacist for advice on how to administer the dose more easily.

Is it safe to take Enalapril Maleate Oral Liquid during pregnancy?

Enalapril Maleate may be harmful during pregnancy, especially in the second and third trimesters. Inform your doctor if you are pregnant or planning to become pregnant before starting this medication. Alternative treatments that are safer during pregnancy may be recommended by your healthcare provider.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.