This formulation combines Diphenhydramine HCl 12.5 mg, Hydrocortisone 2 mg, Nystatin 11.3 mg, and Tetracycline 125 mg into square-shaped troches designed to dissolve slowly in the mouth. As the troche dissolves, medication is absorbed through the oral mucosa, providing targeted local treatment and systemic effects where applicable.

Diphenhydramine HCl is an antihistamine that helps reduce allergic reactions, alleviating symptoms such as itching, swelling, and discomfort in the oral cavity. Hydrocortisone, a corticosteroid, offers anti-inflammatory properties, reducing inflammation and pain. Nystatin is an antifungal agent effective against Candida species, making it useful for treating oral fungal infections like thrush. Tetracycline is a broad-spectrum antibiotic that combats bacterial infections, addressing susceptible organisms present in the mouth.

This combination is particularly beneficial for patients experiencing complex oral conditions involving inflammation, allergic reactions, fungal, and bacterial infections simultaneously. It may be used in managing conditions such as oral mucositis, aphthous ulcers, or mixed microbial infections, especially in immunocompromised individuals.

The troche dosage form allows for direct application of the medication to the affected areas in the mouth. The slow dissolution ensures prolonged contact with the oral mucosa, enhancing the therapeutic effects while minimizing systemic side effects. This localized delivery can lead to more effective symptom relief and improved patient compliance.

Patients are advised to allow the troche to dissolve slowly in the mouth without chewing or swallowing it whole. Adhering to the prescribed dosing schedule is important for optimal results. Potential side effects may include mild irritation or a temporary alteration in taste sensation. Patients should report any severe or persistent adverse effects to their healthcare provider promptly.

Prescribers may consider this compounded formulation for patients who require a tailored approach to oral health issues not adequately addressed by standard treatments. Compounding allows for customization to meet specific patient needs, including dose adjustments and ingredient modifications.

If you have any questions, please reach out to us.

When considering the use of Diphenhydramine HCl 12.5 mg/Hydrocortisone 2 mg/Nystatin 11.3 mg/Tetracycline 125 mg Troches, it is crucial to be aware of potential drug interactions that may affect the efficacy and safety of this formulation. Diphenhydramine, an antihistamine, can interact with other central nervous system depressants such as alcohol, benzodiazepines, opioids, and other sedatives, potentially leading to enhanced sedative effects and increased risk of drowsiness or impaired motor function. Patients should be advised to avoid or limit the use of such substances while taking this medication.

Hydrocortisone, a corticosteroid, may interact with medications that affect the immune system, such as immunosuppressants or vaccines. Concurrent use with immunosuppressants may increase the risk of infections, while live vaccines may be less effective or increase the risk of adverse effects. Patients should inform their healthcare provider of any recent or upcoming vaccinations. Additionally, hydrocortisone can interact with nonsteroidal anti-inflammatory drugs (NSAIDs), increasing the risk of gastrointestinal bleeding or ulceration.

Nystatin, an antifungal agent, is generally well-tolerated with minimal systemic absorption, thus having a low potential for drug interactions. However, it is important to consider that concurrent use with other antifungal agents may alter the effectiveness of treatment. Patients should inform their healthcare provider of any other antifungal medications they are taking to ensure optimal therapeutic outcomes.

Tetracycline, an antibiotic, can interact with antacids, calcium supplements, iron products, and laxatives containing magnesium, as these can reduce the absorption and effectiveness of tetracycline. Patients should be advised to take tetracycline at least 1-2 hours before or 4 hours after such products. Additionally, tetracycline may enhance the effects of anticoagulants, such as warfarin, increasing the risk of bleeding. Regular monitoring of blood coagulation parameters is recommended for patients on concurrent anticoagulant therapy.

It is important for both patients and prescribers to be aware of these potential interactions to ensure safe and effective use of this formulation. Patients should provide a complete list of all medications, including over-the-counter drugs and supplements, to their healthcare provider. Prescribers should carefully evaluate the patient's medication regimen and consider any necessary adjustments or monitoring. If you have any questions or concerns regarding drug interactions with this formulation, please reach out to us for further assistance.

This unique formulation combines Diphenhydramine HCl, Hydrocortisone, Nystatin, and Tetracycline into a square-shaped troche designed to dissolve slowly in the mouth. This delivery method allows the active ingredients to be absorbed through the oral mucosa, providing both local and systemic therapeutic effects. The troche form is particularly beneficial for patients who may have difficulty swallowing pills or require localized treatment in the oral cavity.

Diphenhydramine HCl is an antihistamine that works by blocking the action of histamine, a substance in the body that causes allergic symptoms. By inhibiting histamine receptors, Diphenhydramine helps reduce symptoms such as itching, swelling, and redness, making it effective for treating allergic reactions and inflammatory conditions in the oral cavity.

Hydrocortisone is a corticosteroid that reduces inflammation by suppressing the immune response. When absorbed through the oral mucosa, it helps alleviate inflammation and discomfort associated with various oral conditions. Its anti-inflammatory properties make it useful in managing symptoms of oral lesions, ulcers, and other inflammatory conditions.

Nystatin is an antifungal agent that targets fungal infections, particularly those caused by Candida species. It works by binding to the sterols in the fungal cell membrane, causing cell leakage and ultimately cell death. This makes Nystatin effective in treating oral thrush and other fungal infections in the mouth, providing relief from symptoms such as soreness and white patches.

Tetracycline is a broad-spectrum antibiotic that inhibits bacterial protein synthesis, effectively treating bacterial infections. By preventing the growth and multiplication of bacteria, Tetracycline helps manage bacterial infections in the oral cavity, such as those caused by susceptible strains of bacteria. This can be particularly beneficial for patients with oral infections that are resistant to other antibiotics.

The combination of these active ingredients in a troche form allows for a comprehensive approach to treating a variety of oral conditions, including allergic reactions, inflammation, fungal infections, and bacterial infections. The slow dissolution of the troche ensures prolonged contact with the oral mucosa, enhancing the absorption and effectiveness of the medication. This formulation is designed to provide targeted relief while minimizing systemic side effects, making it a versatile option for both local and systemic treatment needs.

If you have any questions about this formulation or its use, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have.

This unique formulation of Diphenhydramine HCl, Hydrocortisone, Nystatin, and Tetracycline in troche form is primarily designed for targeted local or systemic effects through oral mucosa absorption. While it is commonly used for specific conditions, there are several other potential uses that may benefit patients and prescribers seeking alternative therapeutic options. The combination of these active ingredients can be particularly useful in managing complex oral conditions that require a multifaceted approach. For instance, the anti-inflammatory properties of Hydrocortisone can be beneficial in reducing inflammation and discomfort associated with oral lesions or ulcers, while Diphenhydramine HCl, an antihistamine, can help alleviate itching and irritation in the oral cavity.

Additionally, the antifungal properties of Nystatin make this formulation suitable for addressing oral fungal infections, such as oral thrush, especially in patients who may be immunocompromised or undergoing treatments that predispose them to such infections. Tetracycline, a broad-spectrum antibiotic, can be effective in treating bacterial infections in the oral cavity, including those that may not respond to other antibiotics due to resistance. This makes the troche formulation a valuable option for patients with mixed infections or those who have not responded to standard treatments.

Moreover, the troche form allows for prolonged contact with the oral mucosa, enhancing the local effect of the medication and potentially reducing systemic side effects. This can be particularly advantageous for patients who have difficulty swallowing pills or require localized treatment without systemic exposure. The slow dissolution of the troche ensures a steady release of medication, which can improve adherence and therapeutic outcomes. For prescribers, this formulation offers a versatile tool in managing complex oral health issues, providing a comprehensive approach to treatment that addresses multiple symptoms and underlying causes simultaneously.

As with any medication, it is important for both patients and prescribers to consider individual patient needs, potential interactions with other medications, and any underlying health conditions that may affect the use of this formulation. If you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy. We are here to assist you in optimizing patient care and ensuring the safe and effective use of compounded medications.