Sublingual Semaglutide (generic Ozempic®) now available! Get Started
Dashboard
Formulas

Diphenhydramine HCl 1 mg/mL/Lidocaine HCl 10 mg/mL/Misoprostol 0.024 mg/mL/Triamcinolone Acetonide 1.2 mg/mL Oral Rinse

This oral rinse formulation combines Diphenhydramine HCl, Lidocaine HCl, Misoprostol, and Triamcinolone Acetonide to provide comprehensive relief for various oral conditions. It is specifically designed to treat oral mucositis, aphthous ulcers, and other inflammatory oral lesions.

The liquid formulation is intended for therapeutic use by swishing in the mouth and spitting out, as directed by a healthcare professional. It helps reduce bacteria, control plaque, and soothe oral irritations, delivering targeted medication to the oral cavity without the need for swallowing.

Want a different strength?
Click the Text Us button below.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Must be E-Prescribed
Get Started
Generate LeafletShow Leaflet
This medication requires a prescription from your doctor
Trusted by 60,357 patients to date.
A group of faces of our past satisfied patients.
A svg symbol of a mortar and pestle with ingredients going in.
Custom made in our compounding labs.
Sliders that show the customization of ingredients.
Personalized treatment for better results.
User with a gear showing the personalization of the formulation.
All strengths and ingredients are tailored to your needs.
This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.
Diphenhydramine Hydrochloride
Lidocaine Hydrochloride
Misoprostol
Triamcinolone Acetonide
Oral Rinse
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Dosing Calculator

Get general dosing information for a patient by using this calculator.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Formula Information

A small arrow pointing down

This compounded oral rinse combines Diphenhydramine HCl, Lidocaine HCl, Misoprostol, and Triamcinolone Acetonide to provide comprehensive relief for various oral conditions. The formulation is specifically designed to soothe oral irritations, reduce inflammation, alleviate pain, and promote healing within the oral cavity.

Diphenhydramine HCl is an antihistamine that helps in relieving discomfort caused by inflammation and irritation in the mouth. It works by blocking histamine receptors, thereby reducing swelling and pain associated with oral lesions.

Lidocaine HCl acts as a local anesthetic, providing rapid pain relief by numbing the affected areas of the mouth. This helps reduce discomfort during activities such as eating, speaking, or swallowing, enhancing patient comfort and adherence to oral therapies.

Misoprostol is a prostaglandin E1 analog that promotes mucosal healing by increasing blood flow and stimulating the production of protective mucus within the oral cavity. This aids in the repair of damaged tissues and accelerates the healing process of oral ulcers and lesions.

Triamcinolone Acetonide is a potent corticosteroid with anti-inflammatory properties. It reduces inflammation by suppressing the immune response and decreasing the release of inflammatory mediators. This action helps in alleviating redness, swelling, and discomfort associated with various oral inflammatory conditions.

The synergistic effect of these active ingredients targets multiple pathways involved in oral discomfort and inflammation. By combining an antihistamine, anesthetic, mucosal healing agent, and corticosteroid, this oral rinse addresses both the symptoms and underlying causes of

Drug Interactions

A small arrow pointing down

This oral rinse formulation contains Diphenhydramine HCl, Lidocaine HCl, Misoprostol, and Triamcinolone Acetonide, each contributing to its therapeutic effects. Diphenhydramine HCl is an antihistamine that can help alleviate allergic reactions and reduce inflammation in the oral cavity. Lidocaine HCl is a local anesthetic that provides pain relief by numbing the affected area. Misoprostol, a prostaglandin analog, aids in mucosal protection and healing, while Triamcinolone Acetonide, a corticosteroid, reduces inflammation and immune responses in the oral tissues.

When using this formulation, it is important to consider potential drug interactions. Diphenhydramine HCl may interact with other central nervous system depressants, such as alcohol, benzodiazepines, and opioids, potentially enhancing sedative effects. Patients should be advised to avoid or limit the use of these substances while using the oral rinse. Additionally, Diphenhydramine may interact with monoamine oxidase inhibitors (MAOIs), leading to increased anticholinergic effects, and should be used cautiously in patients taking these medications.

Lidocaine HCl, when used in this formulation, is unlikely to cause systemic interactions due to its local application and minimal absorption. However, caution is advised in patients taking antiarrhythmic drugs, as Lidocaine may enhance their effects, potentially leading to cardiac complications. Patients with a history of cardiac conditions should consult their healthcare provider before using this oral rinse.

Misoprostol, although primarily used for its mucosal protective properties in this formulation, can interact with antacids containing magnesium, leading to increased diarrhea. Patients should be advised to use alternative antacids if needed. Additionally, Misoprostol is contraindicated in pregnant women due to its uterotonic effects, which can lead to miscarriage or premature labor. Women of childbearing potential should use effective contraception while using this formulation and consult their healthcare provider if pregnancy is planned or suspected.

Triamcinolone Acetonide, as a corticosteroid, may interact with other immunosuppressive agents, potentially increasing the risk of infections. Patients should be monitored for signs of infection and advised to report any unusual symptoms to their healthcare provider. Additionally, prolonged use of corticosteroids can lead to systemic effects, such as adrenal suppression, especially in patients using other forms of corticosteroids. It is important to follow the prescribed duration and dosage to minimize these risks.

Overall, this oral rinse formulation is designed to provide targeted relief for oral conditions while minimizing systemic exposure. Patients and prescribers should be aware of these potential interactions and use the formulation as directed. If you have any questions or concerns about using this formulation, please reach out to us for further guidance.

How Does it Work

A small arrow pointing down

This liquid formulation is a compounded oral rinse that combines the therapeutic effects of Diphenhydramine HCl, Lidocaine HCl, Misoprostol, and Triamcinolone Acetonide to address various oral conditions. Each component plays a specific role in alleviating symptoms and promoting oral health. The formulation is designed for swishing in the mouth and spitting out, allowing the active ingredients to act directly on the affected areas without systemic absorption, unless otherwise directed by a healthcare professional.

Diphenhydramine HCl, an antihistamine, works by blocking histamine receptors in the oral cavity. This action helps reduce inflammation and alleviate symptoms such as itching, swelling, and discomfort associated with allergic reactions or irritations in the mouth. By mitigating these symptoms, Diphenhydramine HCl contributes to a more comfortable oral environment, facilitating healing and reducing the urge to scratch or further irritate the affected areas.

Lidocaine HCl is a local anesthetic that provides temporary relief from pain and discomfort in the oral cavity. It works by blocking sodium channels in nerve cells, which prevents the transmission of pain signals to the brain. This numbing effect is particularly beneficial for patients experiencing oral pain due to conditions such as mouth ulcers, sores, or other irritations. By reducing pain, Lidocaine HCl allows patients to perform daily oral functions, such as eating and speaking, with less discomfort.

Misoprostol, a prostaglandin analog, plays a crucial role in promoting mucosal protection and healing. It stimulates the production of protective mucus and bicarbonate in the oral cavity, which helps shield the mucosal lining from irritants and potential damage. Additionally, Misoprostol enhances blood flow to the affected areas, supporting tissue repair and regeneration. This component is particularly useful in managing conditions that involve mucosal damage or ulceration, as it aids in restoring the integrity of the oral tissues.

Triamcinolone Acetonide is a corticosteroid that exerts potent anti-inflammatory effects. It works by inhibiting the release of inflammatory mediators and suppressing the immune response in the oral cavity. This action helps reduce swelling, redness, and discomfort associated with inflammatory oral conditions, such as lichen planus or aphthous stomatitis. By controlling inflammation, Triamcinolone Acetonide promotes a more conducive environment for healing and reduces the risk of further tissue damage.

Together, these active ingredients provide a comprehensive approach to managing oral conditions by addressing pain, inflammation, irritation, and mucosal protection. The formulation is particularly effective for patients who require targeted treatment of oral symptoms without systemic side effects. It is important for patients to follow the prescribed usage instructions, typically involving swishing the liquid in the mouth for a specified duration before spitting it out, to ensure optimal therapeutic outcomes.

If you have any questions about this formulation or its use, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to both patients and prescribers.

Other Uses

A small arrow pointing down

This compounded oral rinse formulation, containing Diphenhydramine HCl, Lidocaine HCl, Misoprostol, and Triamcinolone Acetonide, is primarily designed for therapeutic use in managing oral conditions such as mucositis, oral ulcers, and other inflammatory or painful oral lesions. However, beyond these primary indications, this formulation may have other potential uses that could be beneficial for both patients and prescribers to consider. The combination of ingredients provides a multifaceted approach to oral care, offering anti-inflammatory, anesthetic, and protective properties that can be advantageous in various scenarios.

For patients undergoing chemotherapy or radiation therapy, this oral rinse can be particularly useful in managing oral mucositis, a common and painful side effect of these treatments. The anti-inflammatory properties of Triamcinolone Acetonide, combined with the soothing effects of Lidocaine, can help alleviate pain and inflammation, while Misoprostol may aid in mucosal protection and healing. Additionally, Diphenhydramine's antihistamine properties can help reduce discomfort associated with oral allergies or irritations.

In dental settings, this formulation may be used as a pre-procedural rinse to reduce oral bacteria and minimize the risk of infection during dental procedures. The anesthetic effect of Lidocaine can also provide temporary relief from dental pain or discomfort, making it a useful adjunct in managing conditions like oral lichen planus or aphthous stomatitis. Furthermore, the rinse can be beneficial for patients with autoimmune conditions affecting the oral cavity, such as pemphigus vulgaris or Sjögren's syndrome, by providing symptomatic relief and promoting oral health.

For prescribers, it is important to consider the individual patient's needs and medical history when recommending this formulation. The combination of active ingredients offers a comprehensive approach to oral care, but it is essential to ensure that the patient does not have any contraindications or allergies to the components. Additionally, prescribers should provide clear instructions on the use of the rinse, emphasizing the importance of swishing and spitting without swallowing, to maximize therapeutic benefits while minimizing systemic absorption.

If you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or specific patient needs you may have.

Frequently Asked Questions

A small arrow pointing down

What is the purpose of this compounded oral rinse formulation?

This liquid formulation is designed for oral use to treat various oral conditions, reduce bacteria, control plaque, soothe oral irritations, and deliver medication directly to the oral cavity. It is often used by swishing in the mouth and spitting out without swallowing, as directed by a healthcare professional.

How should I use this oral rinse?

Use this oral rinse by swishing the prescribed amount in your mouth for the recommended duration, then spit it out. Do not swallow the rinse. Follow the specific instructions provided by your healthcare professional.

Can I swallow this oral rinse?

No, this oral rinse is not intended to be swallowed. It should be used by swishing in the mouth and then spitting out, as directed by your healthcare professional.

What are the active ingredients in this oral rinse?

The active ingredients in this oral rinse are Diphenhydramine HCl 1 mg/mL, Lidocaine HCl 10 mg/mL, Misoprostol 0.024 mg/mL, and Triamcinolone Acetonide 1.2 mg/mL.

What conditions can this oral rinse help treat?

This oral rinse can help treat oral conditions such as mouth sores, oral irritations, and inflammation. It may also be used to reduce bacteria and control plaque in the oral cavity.

Are there any side effects associated with this oral rinse?

Possible side effects may include temporary numbness or tingling in the mouth, mild irritation, or an allergic reaction. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

How often should I use this oral rinse?

The frequency of use will be determined by your healthcare professional based on your specific condition and needs. Follow their instructions carefully.

Can children use this oral rinse?

Use in children should be determined by a healthcare professional. It is important to follow their guidance and ensure the child does not swallow the rinse.

How should I store this oral rinse?

Store the oral rinse at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

What should I do if I accidentally swallow the oral rinse?

If you accidentally swallow the oral rinse, contact your healthcare provider or seek medical attention immediately, especially if you experience any adverse effects.

Related Formulas

Related Products
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.