Sublingual Semaglutide (generic Ozempic®) now available! Get Started
Dashboard
Formulas

Diphenhydramine HCl 1 mg/mL/Doxycycline Hyclate 2 mg/mL/Hydrocortisone 1.0 mg/mL Oral Suspension

This oral suspension is a liquid dosage form where Diphenhydramine HCl, Doxycycline Hyclate, and Hydrocortisone are uniformly dispersed in a liquid medium, ensuring a homogeneous mixture for effective administration.

Formulated to treat allergic reactions, bacterial infections, and inflammatory conditions, this suspension combines the antihistamine properties of Diphenhydramine HCl, the antibiotic effects of Doxycycline Hyclate, and the anti-inflammatory benefits of Hydrocortisone.

Want a different strength?
Click the Text Us button below.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Must be E-Prescribed
Get Started
Generate LeafletShow Leaflet
This medication requires a prescription from your doctor
Trusted by 60,357 patients to date.
A group of faces of our past satisfied patients.
A svg symbol of a mortar and pestle with ingredients going in.
Custom made in our compounding labs.
Sliders that show the customization of ingredients.
Personalized treatment for better results.
User with a gear showing the personalization of the formulation.
All strengths and ingredients are tailored to your needs.
This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.
Diphenhydramine Hydrochloride
Doxycycline Hyclate
Hydrocortisone
Suspension
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Dosing Calculator

Get general dosing information for a patient by using this calculator.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Formula Information

A small arrow pointing down

This compounded oral suspension contains Diphenhydramine HCl at a concentration of 1 mg/mL, Doxycycline Hyclate at 2 mg/mL, and Hydrocortisone at 1.0 mg/mL. These active ingredients are uniformly dispersed in a liquid medium to provide a homogeneous mixture for administration. This formulation is designed to deliver the antihistaminic, antibacterial, and anti-inflammatory effects of its constituents in a single, convenient dosage form.

Diphenhydramine HCl is an antihistamine that works by blocking histamine receptors, thereby reducing allergic symptoms such as itching, sneezing, and runny nose. It is commonly used to relieve symptoms associated with allergies, hay fever, and the common cold. By reducing histamine-mediated effects, it helps alleviate discomfort caused by allergic reactions.

Doxycycline Hyclate is a broad-spectrum tetracycline antibiotic that inhibits bacterial protein synthesis, effectively stopping the growth of bacteria. It is used to treat a variety of bacterial infections, including respiratory tract infections, skin infections, and certain types of infections that are resistant to other antibiotics. Its inclusion in this suspension allows for the treatment of bacterial infections that may be associated with inflammatory conditions.

Hydrocortisone is a corticosteroid that reduces inflammation by suppressing the immune response and decreasing the formation of substances that cause inflammation. It helps alleviate symptoms such as swelling, redness, and pain. The anti-inflammatory properties of hydrocortisone complement the effects of the other ingredients, providing comprehensive relief from both the cause and symptoms of certain conditions.

This compounded formulation may be particularly beneficial for patients who require simultaneous management of allergic reactions, bacterial infections, and inflammation. Combining these medications into a single oral suspension enhances patient compliance, especially for those who have difficulty swallowing pills, such as children or the elderly. It also allows for tailored dosing to meet specific patient needs.

Patients should take this medication exactly as prescribed by their healthcare provider. The dosage and duration of treatment depend on the medical condition and response

Drug Interactions

A small arrow pointing down

This compounded oral suspension contains Diphenhydramine HCl, Doxycycline Hyclate, and Hydrocortisone, each of which can interact with other medications, potentially altering their effects or increasing the risk of adverse reactions. It is crucial for both patients and prescribers to be aware of these interactions to ensure safe and effective use of this formulation.

Diphenhydramine HCl, an antihistamine, can cause sedation and drowsiness. When taken with other central nervous system depressants such as alcohol, benzodiazepines, opioids, or other sedating antihistamines, there is an increased risk of enhanced sedation and respiratory depression. Patients should be advised to avoid or limit the use of these substances while taking this formulation. Additionally, diphenhydramine may interact with monoamine oxidase inhibitors (MAOIs), potentially leading to increased anticholinergic effects such as dry mouth, urinary retention, and constipation.

Doxycycline Hyclate, a tetracycline antibiotic, can interact with antacids and supplements containing calcium, magnesium, aluminum, or iron, as these can bind to doxycycline and reduce its absorption and effectiveness. Patients should be instructed to take doxycycline at least 1-2 hours before or after consuming these products. Doxycycline may also enhance the effects of anticoagulants like warfarin, increasing the risk of bleeding. Regular monitoring of coagulation parameters is recommended when these drugs are used concurrently. Additionally, doxycycline can reduce the efficacy of oral contraceptives, so alternative or additional contraceptive measures should be considered.

Hydrocortisone, a corticosteroid, can interact with nonsteroidal anti-inflammatory drugs (NSAIDs) and increase the risk of gastrointestinal bleeding. Patients should be advised to use caution when taking NSAIDs concurrently. Hydrocortisone may also interact with certain antidiabetic medications, potentially leading to altered blood glucose levels. Patients with diabetes should monitor their blood sugar levels closely and consult their healthcare provider for any necessary adjustments to their diabetes medication regimen. Furthermore, hydrocortisone can interact with other immunosuppressive agents, potentially increasing the risk of infections.

It is important for prescribers to review the patient's current medication list for potential interactions and adjust therapy as needed. Patients should be encouraged to report any unusual symptoms or side effects to their healthcare provider promptly. If you have any questions or need further information, please reach out to us at Bayview Pharmacy.

How Does it Work

A small arrow pointing down

This compounded oral suspension combines Diphenhydramine HCl, Doxycycline Hyclate, and Hydrocortisone in a liquid dosage form, ensuring a homogeneous mixture for effective administration. Each component plays a distinct role in addressing various disease states, providing a multifaceted approach to treatment.

Diphenhydramine HCl, at a concentration of 1 mg/mL, is an antihistamine that works by blocking the action of histamine, a substance in the body that causes allergic symptoms. By inhibiting histamine receptors, Diphenhydramine helps alleviate symptoms such as itching, swelling, and rashes, making it effective in treating allergic reactions and conditions like urticaria and allergic rhinitis. Its sedative properties also contribute to reducing discomfort and promoting rest, which can be beneficial in managing symptoms that disrupt sleep.

Doxycycline Hyclate, present at 2 mg/mL, is a broad-spectrum antibiotic belonging to the tetracycline class. It functions by inhibiting protein synthesis in bacteria, thereby preventing their growth and proliferation. This makes it effective in treating a variety of bacterial infections, including respiratory tract infections, skin infections, and certain types of acne. By addressing the bacterial component of infections, Doxycycline helps reduce inflammation and prevent the spread of infection, contributing to faster recovery and symptom relief.

Hydrocortisone, included at 1.0 mg/mL, is a corticosteroid that exerts anti-inflammatory and immunosuppressive effects. It works by reducing the production of substances in the body that cause inflammation, thereby alleviating symptoms such as redness, swelling, and pain. Hydrocortisone is particularly useful in managing inflammatory conditions and can be effective in treating conditions like eczema, psoriasis, and other dermatological disorders. Its inclusion in the formulation helps to quickly reduce inflammation and improve patient comfort.

The combination of these three active ingredients in a liquid suspension allows for precise dosing and easy administration, particularly beneficial for patients who may have difficulty swallowing tablets or capsules. The uniform dispersion of the ingredients ensures consistent therapeutic effects with each dose, enhancing the overall efficacy of the treatment regimen.

This formulation is designed to provide comprehensive relief by addressing multiple pathways involved in allergic reactions, bacterial infections, and inflammatory conditions. Patients and prescribers can expect a synergistic effect from the combined action of Diphenhydramine, Doxycycline, and Hydrocortisone, leading to improved outcomes and patient satisfaction. If you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy.

Other Uses

A small arrow pointing down

The Diphenhydramine HCl 1 mg/mL/Doxycycline Hyclate 2 mg/mL/Hydrocortisone 1.0 mg/mL Oral Suspension is a versatile formulation that can be utilized for a variety of off-label uses beyond its primary indications. This liquid dosage form ensures that the active ingredients are evenly distributed throughout the suspension, allowing for consistent dosing and ease of administration, particularly beneficial for patients who have difficulty swallowing pills or require precise dosing adjustments.

Diphenhydramine HCl, an antihistamine, is commonly used for its sedative properties and can be beneficial in managing symptoms of insomnia or anxiety in certain patients. Its ability to cross the blood-brain barrier allows it to exert a calming effect, which can be particularly useful in patients experiencing agitation or restlessness. Additionally, diphenhydramine's anticholinergic properties may provide relief in cases of motion sickness or nausea, offering an alternative to traditional antiemetic medications.

Doxycycline Hyclate, a broad-spectrum antibiotic, is often employed in the treatment of various bacterial infections. However, its anti-inflammatory properties make it a potential candidate for managing conditions such as rosacea or acne, where inflammation plays a significant role. Furthermore, doxycycline has been explored for its role in treating certain autoimmune conditions, such as rheumatoid arthritis, due to its ability to modulate the immune response.

Hydrocortisone, a corticosteroid, is widely recognized for its anti-inflammatory and immunosuppressive effects. In this formulation, it can be used to manage inflammatory conditions of the gastrointestinal tract, such as mild to moderate cases of inflammatory bowel disease (IBD) or eosinophilic esophagitis. Additionally, hydrocortisone may be beneficial in treating adrenal insufficiency or Addison's disease, where oral administration of corticosteroids is required to replace deficient hormones.

For both patients and prescribers, it is important to consider the potential interactions and side effects associated with each component of this formulation. Diphenhydramine may cause drowsiness or dry mouth, while doxycycline can lead to photosensitivity or gastrointestinal upset. Hydrocortisone, when used long-term, may result in systemic effects such as weight gain or increased blood pressure. Therefore, careful monitoring and consultation with a healthcare professional are advised when using this formulation for off-label purposes.

If you have any questions or require further information about the potential uses of this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have.

Frequently Asked Questions

A small arrow pointing down

What is the purpose of this compounded formulation?

This compounded formulation combines Diphenhydramine HCl, Doxycycline Hyclate, and Hydrocortisone to provide a multi-faceted treatment approach. Diphenhydramine HCl is an antihistamine, Doxycycline Hyclate is an antibiotic, and Hydrocortisone is a corticosteroid, which together can help manage symptoms such as allergies, infections, and inflammation.

How should I store this oral suspension?

This oral suspension should be stored in a cool, dry place away from direct sunlight. It is important to keep it at room temperature unless otherwise directed by your pharmacist or healthcare provider. Always keep the bottle tightly closed when not in use.

How do I properly administer this oral suspension?

Shake the bottle well before each use to ensure the ingredients are evenly distributed. Use a proper measuring device, such as an oral syringe or dosing cup, to ensure accurate dosing. Follow the dosage instructions provided by your healthcare provider.

Can this formulation be used for children?

The use of this formulation in children should be determined by a healthcare provider. Dosage and safety can vary based on the child's age, weight, and medical condition, so it is important to consult a healthcare professional before administering it to children.

Are there any potential side effects of this formulation?

As with any medication, there may be potential side effects. Common side effects can include drowsiness, dizziness, upset stomach, or dry mouth. If you experience severe side effects or an allergic reaction, seek medical attention immediately.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Can I take this formulation with other medications?

Before taking this formulation with other medications, consult your healthcare provider or pharmacist. There may be potential interactions with other drugs, which could affect the efficacy or increase the risk of side effects.

How long can I use this oral suspension?

The duration of use should be determined by your healthcare provider based on your specific condition and response to treatment. Do not use this medication for longer than prescribed without consulting your healthcare provider.

What should I do if I experience an allergic reaction?

If you experience symptoms of an allergic reaction, such as rash, itching, swelling, severe dizziness, or trouble breathing, seek immediate medical attention. Discontinue use of the medication and inform your healthcare provider.

Is it safe to use this formulation during pregnancy or breastfeeding?

The safety of this formulation during pregnancy or breastfeeding should be discussed with your healthcare provider. They will weigh the potential benefits and risks before recommending its use in these situations.

Related Formulas

Related Products
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.