This compounded oral suspension combines Diphenhydramine HCl 1.25 mg/mL, Hydrocortisone 0.5 mg/mL, Nystatin 20,000 Units/mL, and Tetracycline 12.5 mg/mL in a homogeneous liquid dosage form designed for oral administration. The suspension ensures that each active ingredient is uniformly dispersed throughout the liquid medium, allowing for consistent dosing and effective treatment.

Diphenhydramine HCl acts as an antihistamine, providing relief from discomfort caused by allergic reactions in the oral cavity. It helps reduce symptoms such as itching, swelling, and pain. Hydrocortisone, a corticosteroid, works by reducing inflammation and suppressing immune responses, which can alleviate inflammation and irritation in the mouth.

Nystatin is an antifungal medication effective against Candida species, making it valuable for treating and preventing oral fungal infections like thrush. Tetracycline, a broad-spectrum antibiotic, inhibits bacterial protein synthesis, helping to combat a variety of bacterial infections that may be present in the oral mucosa.

The combination of these ingredients addresses multiple potential causes of oral discomfort and lesions, including bacterial infections, fungal infections, inflammatory responses, and allergic reactions. This makes the formulation particularly useful for patients experiencing complex oral conditions where multiple therapeutic actions are beneficial.

Patients are advised to use this oral suspension as directed by their healthcare provider. The liquid form allows for easy administration and ensures direct contact of the medication with the affected areas in the mouth, enhancing the therapeutic effects. It's important to shake the bottle well before each use to ensure the proper distribution of the active ingredients.

Prescribers may consider this formulation for patients requiring a comprehensive treatment approach to oral mucosal conditions. The suspension can be tailored to meet specific patient needs, and dosing can be adjusted based on the severity of symptoms and response to therapy.

If you have any questions, reach out to us.

This compounded oral suspension contains Diphenhydramine HCl, Hydrocortisone, Nystatin, and Tetracycline, each of which can interact with other medications, potentially altering their effects or increasing the risk of adverse reactions. It is crucial for both patients and prescribers to be aware of these interactions to ensure safe and effective use of this formulation.

Diphenhydramine HCl, an antihistamine, can cause sedation and may enhance the sedative effects of other central nervous system depressants, such as alcohol, benzodiazepines, opioids, and certain antidepressants. Patients should be advised to avoid or limit the use of these substances while taking this medication. Additionally, diphenhydramine may interact with monoamine oxidase inhibitors (MAOIs), potentially leading to increased anticholinergic effects, such as dry mouth, constipation, and urinary retention.

Hydrocortisone, a corticosteroid, can interact with a variety of medications. It may increase blood glucose levels, potentially reducing the efficacy of antidiabetic drugs. Patients with diabetes should monitor their blood sugar levels closely. Concurrent use with nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal bleeding. Hydrocortisone can also affect the metabolism of certain drugs, such as warfarin, leading to altered anticoagulant effects. Regular monitoring of INR levels is recommended for patients on warfarin therapy.

Nystatin, an antifungal agent, is generally well-tolerated and has minimal systemic absorption when used orally. However, it is important to note that nystatin may interact with other antifungal medications, potentially leading to reduced efficacy. Patients should inform their healthcare provider of all antifungal treatments they are currently using to avoid potential interactions.

Tetracycline, an antibiotic, can interact with various medications and supplements. It may bind to calcium, magnesium, aluminum, and iron, reducing its absorption and effectiveness. Patients should avoid taking tetracycline with dairy products, antacids, or iron supplements. Additionally, tetracycline can decrease the effectiveness of oral contraceptives, so alternative or additional contraceptive measures should be considered. It may also interact with anticoagulants, potentially enhancing their effects and increasing the risk of bleeding.

Patients and prescribers should be vigilant about potential drug interactions when using this compounded oral suspension. A comprehensive review of the patient's current medication regimen, including over-the-counter drugs and supplements, is essential to minimize the risk of adverse interactions. If you have any questions or concerns about drug interactions with this formulation, please reach out to us for further assistance.

This compounded oral suspension is a carefully formulated medication designed to deliver a combination of active ingredients, each serving a specific therapeutic purpose. The liquid dosage form ensures that the ingredients are uniformly dispersed throughout the medium, providing a homogeneous mixture that facilitates accurate dosing and ease of administration. This formulation is particularly beneficial for patients who may have difficulty swallowing tablets or capsules, such as children or the elderly, and allows for flexible dosing adjustments as needed.

Diphenhydramine HCl, an antihistamine, works by blocking the action of histamine, a substance in the body that causes allergic symptoms. By inhibiting histamine receptors, diphenhydramine helps alleviate symptoms such as itching, swelling, and rashes, making it effective in treating allergic reactions and certain skin conditions. Its sedative properties can also provide relief from discomfort and promote rest, which is beneficial in managing symptoms that may disrupt sleep.

Hydrocortisone, a corticosteroid, functions by reducing inflammation and suppressing the immune response. It is effective in treating inflammatory conditions and can help decrease redness, swelling, and irritation. By modulating the body's immune response, hydrocortisone aids in the management of conditions that involve excessive inflammation, providing relief from discomfort and promoting healing.

Nystatin is an antifungal agent that targets fungal infections, particularly those caused by Candida species. It works by binding to the sterols in the fungal cell membrane, creating pores that lead to the leakage of essential cellular components, ultimately causing cell death. This action makes nystatin effective in treating oral thrush and other fungal infections of the mouth and throat, helping to restore a healthy microbial balance.

Tetracycline, a broad-spectrum antibiotic, inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing the addition of amino acids to the growing peptide chain. This action effectively halts bacterial growth and replication, making tetracycline useful in treating a variety of bacterial infections. Its inclusion in this formulation helps address bacterial components of mixed infections, ensuring comprehensive antimicrobial coverage.

The combination of these active ingredients in a single oral suspension allows for a multifaceted approach to treatment, addressing allergic, inflammatory, fungal, and bacterial components of disease states. This synergistic effect can enhance therapeutic outcomes, providing comprehensive relief and promoting recovery. Patients and prescribers can benefit from the convenience and efficacy of this compounded formulation, tailored to meet specific clinical needs. If you have any questions or require further information, please reach out to us at Bayview Pharmacy.

This compounded oral suspension, containing Diphenhydramine HCl, Hydrocortisone, Nystatin, and Tetracycline, is primarily formulated to address specific conditions that may benefit from the combined effects of an antihistamine, anti-inflammatory, antifungal, and antibiotic. However, beyond its primary indications, this formulation may have other potential uses that could be considered by healthcare providers based on their clinical judgment and patient-specific needs. For instance, the combination of these active ingredients might be utilized in managing complex oral or esophageal conditions where inflammation, infection, and allergic reactions coexist, such as in certain cases of oral mucositis or esophagitis, particularly when these conditions are refractory to standard treatments.

Diphenhydramine HCl, an antihistamine, can help alleviate symptoms of allergic reactions, such as itching and swelling, which might be beneficial in conditions where histamine release is a contributing factor. Hydrocortisone, a corticosteroid, provides anti-inflammatory effects that can reduce inflammation and discomfort in the oral cavity or esophagus. Nystatin, an antifungal, is effective against Candida species, making it useful in treating or preventing oral thrush, especially in immunocompromised patients or those undergoing treatments that predispose them to fungal infections. Tetracycline, a broad-spectrum antibiotic, can address bacterial infections that may accompany or complicate other conditions.

For prescribers, it is crucial to consider the patient's overall health status, potential drug interactions, and the specific pathogens involved when contemplating the use of this formulation for off-label purposes. The combination of these agents in a liquid suspension allows for ease of administration, particularly in patients who have difficulty swallowing pills or require precise dosing adjustments. Patients should be informed about the potential side effects of each component, such as drowsiness from Diphenhydramine, potential adrenal suppression from Hydrocortisone, gastrointestinal disturbances from Tetracycline, and the importance of adhering to the prescribed regimen to prevent resistance or recurrence of infection.

As with any compounded medication, the decision to use this formulation for other than its primary indications should be made collaboratively between the prescriber and the patient, considering the potential benefits and risks. If you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy. We are here to assist both patients and healthcare providers in making informed decisions about compounded medications.