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Formulas

Diclofenac Sodium 3%/Lidocaine 5% Topical Cream

Diclofenac Sodium 3%/Lidocaine 5% Topical Cream is a semisolid preparation that combines the anti-inflammatory and analgesic properties of Diclofenac Sodium with the local anesthetic effects of Lidocaine. This cream is specifically formulated for topical application and is dispensed in a pump mechanism, which allows for convenient and controlled dosing. The cream is designed to be applied directly to the skin over the affected area, providing localized treatment to reduce pain and inflammation.

This formulation is commonly used to treat a variety of disease states, including localized musculoskeletal pain, osteoarthritis-related discomfort, and certain types of neuropathic pain. It may also be prescribed for the relief of pain associated with sports injuries, sprains, strains, and bruises. The combination of Diclofenac Sodium and Lidocaine works synergistically to alleviate pain at the site of application, offering patients a non-invasive treatment option with minimal systemic absorption.

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Topical Cream
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Formula Information

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The Diclofenac Sodium 3%/Lidocaine 5% Topical Cream is a specially compounded medication that combines the anti-inflammatory and analgesic properties of Diclofenac Sodium with the local anesthetic effects of Lidocaine. This cream is formulated as a semisolid preparation, which is dispensed from a pump mechanism. This delivery system is designed to provide patients with a convenient and controlled method of application, ensuring consistent dosing and targeted relief to specific areas of the skin.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. When applied topically, it is used to treat joint pain caused by osteoarthritis. Lidocaine, on the other hand, is a local anesthetic that provides temporary relief of pain by blocking nerve signals in the body. The combination of these two active ingredients in a 3% and 5% concentration respectively, allows for effective management of pain and inflammation with a reduced risk of systemic side effects typically associated with oral NSAIDs.

This topical cream is particularly useful for patients who require localized pain relief and prefer to avoid the gastrointestinal side effects that can accompany systemic medications. It is indicated for the treatment of inflammatory and pain conditions such as osteoarthritis of the knees, hands, and other joints, as well as for the relief of neuropathic pain or other conditions where an anti-inflammatory and anesthetic effect is desired. The cream can be applied directly to the affected area, providing targeted action and rapid onset of pain relief.

For optimal results, the cream should be applied as directed by a healthcare provider, usually 2-4 times daily, or as needed for pain control. It is important to follow the specific instructions provided with the prescription, as the concentration of active ingredients has been tailored for individual needs. Patients should wash their hands before and after applying the cream, unless the hands are the treated area. It is also crucial to avoid contact with eyes, mucous membranes, and open wounds.

As with any medication, there may be potential side effects, and it is important to monitor for signs of skin irritation or allergic reaction. Patients should report any unusual symptoms or concerns to their healthcare provider promptly. Additionally, patients should inform their healthcare provider of all medications they are taking, as there may be interactions with other topical or systemic drugs.

Bayview Pharmacy is committed to providing high-quality, customized medications to meet the specific needs of our patients. If you have any questions about the Diclofenac Sodium 3%/Lidocaine 5% Topical Cream or its appropriate use, please do not hesitate to reach out to us. Our team of expert compounding pharmacists is here to support both patients and prescribers with any information or guidance needed to ensure safe and effective treatment.

Drug Interactions

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The combination of Diclofenac Sodium and Lidocaine in a topical cream is designed to provide localized relief from pain and inflammation. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. Lidocaine is a local anesthetic that provides temporary numbness and relief from pain by blocking nerve signals in the specific area it is applied to. This formulation is particularly useful in treating localized musculoskeletal pain, such as sprains, strains, or other injuries, as well as conditions like arthritis or bursitis.

When using this Diclofenac Sodium 3%/Lidocaine 5% Topical Cream, it is important to consider potential drug interactions. Diclofenac, even when used topically, may interact with other NSAIDs (including aspirin), increasing the risk of gastrointestinal bleeding or ulcers. It is advisable to avoid concurrent use with other NSAID-containing products unless directed by a healthcare provider. Additionally, diclofenac may interact with anticoagulants (such as warfarin), antiplatelet agents, selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs), potentially increasing the risk of bleeding. Patients should inform their healthcare provider if they are taking any of these medications.

Lidocaine, when applied topically, is generally considered to have a low risk of systemic interactions due to minimal absorption. However, caution is advised when it is used in conjunction with other local anesthetics or medications that affect cardiac conduction, as there is a potential for additive systemic effects. Patients with a history of cardiac disease should use lidocaine-containing products under close supervision.

It is also important to note that the use of topical diclofenac may be contraindicated in patients with a known hypersensitivity to diclofenac, aspirin, or other NSAIDs, as well as in patients who have experienced asthma, urticaria, or allergic-type reactions after taking these medications. Similarly, patients with a known hypersensitivity to lidocaine, other amide-type local anesthetics, or any other component of the formulation should not use this product.

Patients should be advised to apply the cream only to intact skin and avoid contact with the eyes, mucous membranes, and open wounds. The use of occlusive dressings over the application site is not recommended unless directed by a healthcare provider. Additionally, patients should be instructed to wash their hands after applying the cream unless the hands are the treated area.

As with any medication, it is essential for patients to inform their healthcare providers of all the medications they are currently taking, including over-the-counter drugs, vitamins, and herbal supplements, to avoid potential interactions. If you have any questions or concerns regarding the use of Diclofenac Sodium 3%/Lidocaine 5% Topical Cream or its potential interactions with other medications, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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The Diclofenac Sodium 3%/Lidocaine 5% Topical Cream is a specially formulated medication that combines the anti-inflammatory and analgesic properties of Diclofenac Sodium with the local anesthetic effects of Lidocaine. This cream is designed to be applied directly to the skin where it can provide targeted relief from pain and inflammation.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the cyclooxygenase (COX) enzymes, which are involved in the synthesis of prostaglandins. Prostaglandins are lipid compounds that play a key role in the inflammation process, including pain and swelling. By reducing the production of these compounds, Diclofenac Sodium can help to alleviate localized inflammation and pain associated with conditions such as osteoarthritis, rheumatoid arthritis, and other musculoskeletal disorders.

Lidocaine, on the other hand, is a local anesthetic that works by blocking sodium channels in the neuronal cell membrane. This action inhibits the initiation and conduction of nerve impulses, thereby providing a numbing effect. When applied topically, Lidocaine can help to reduce the sensation of pain in the area of application. This can be particularly beneficial for patients experiencing sharp, shooting, or burning types of pain.

The combination of these two active ingredients in a topical cream allows for the synergistic effects of pain relief and inflammation reduction directly at the site of discomfort. The cream is formulated as a semisolid preparation, which ensures that it can be easily spread over the affected area. The inclusion of a pump mechanism in the packaging allows for convenient and controlled dispensing of the medication, ensuring that patients can apply a consistent dose each time. This is particularly useful for maintaining the correct dosing regimen and for ensuring that the medication is applied only to the intended area.

This topical cream is indicated for the treatment of localized pain and inflammation and can be particularly useful for patients who may be unable to tolerate oral NSAIDs or who prefer a targeted approach to pain management. It is important to note that while this cream can provide significant relief from symptoms, it is not a cure for the underlying conditions. Patients should use this medication as directed by their healthcare provider and should report any adverse effects or lack of improvement in their symptoms.

For patients and prescribers considering the use of this formulation, it is essential to understand the mechanism of action, the appropriate application technique, and the potential benefits and risks. If you have any questions or require further information about the Diclofenac Sodium 3%/Lidocaine 5% Topical Cream, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide the support and guidance you need to ensure safe and effective treatment.

Other Uses

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Diclofenac Sodium and Lidocaine cream is primarily prescribed for its analgesic and anti-inflammatory properties. While it is predominantly used to provide relief from various forms of pain and inflammation, such as in conditions like osteoarthritis, sports injuries, or after certain surgical procedures, there can be alternative applications which may benefit from its dual-action formula. For instance, this cream may be found useful in other soft tissue injuries where inflammation is a significant component or in localized neuropathic pain syndromes due to the presence of lidocaine, which provides a numbing effect to calm overactive pain signals.

In addition, individuals suffering from skin conditions that have an inflammatory pain component may find symptomatic relief when using this preparation. Conditions like tendonitis, bursitis, or certain skin lesions that are painful might also respond to the anti-inflammatory and analgesic effects of this topical cream. However, it's crucial to consult with a healthcare provider before using this preparation for off-label uses to assess suitability and avoid potential contraindications or adverse effects.

Moreover, this formulation may be considered in the management of localized joint pain, especially in instances where oral NSAIDs present gastrointestinal risks or are contraindicated. It is essential for both patients and prescribers to note that while the systemic absorption of the active ingredients is lower compared to oral medications, systemic exposure can still occur, which should be taken into account when assessing patient suitability for the treatment.

Patients who are sensitive to oral NSAIDs or who prefer a localized approach to managing pain might particularly benefit from this formulation. The convenience of a pump mechanism allows for easier dosing and ensures that the patient receives a consistent amount with each application, contributing to the overall effectiveness and ease of use of the medication.

It must be noted, however, that the use of Diclofenac Sodium 3%/Lidocaine 5% Topical Cream should always follow the prescribing information, and consideration should be given to any potential for adverse effects or drug interactions, particularly in patients using other local anesthetics or NSAIDs. We always encourage both patients and prescribers to reach out to us at Bayview Pharmacy with any questions or concerns regarding the uses and potential benefits of this topical cream formulation. Our team is committed to ensuring the safe and effective use of the medications we compound and helping our patients achieve optimal therapeutic outcomes.

Frequently Asked Questions

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What is Diclofenac Sodium 3%/Lidocaine 5% Topical Cream used for?

This topical cream is used for providing localized relief from pain and inflammation. The active ingredients, Diclofenac Sodium, an NSAID, and Lidocaine, an anesthetic, work together to reduce pain and discomfort in targeted areas of the skin.

How do you apply this compounded cream?

To apply, simply press the pump to dispense the cream onto your finger or directly onto the affected area, then gently rub into the skin until fully absorbed. Make sure the area is clean and dry before application.

How often can I use this topical cream?

Your healthcare provider will advise you on how often to use the cream. Generally, it is applied to the affected area 2-4 times daily, depending on the severity of symptoms and physician recommendations.

Can this cream be used on any part of the body?

While it can be used on many parts of the body, it should not be applied to open wounds, or mucous membranes. Avoid contact with the eyes, mouth, and any other area where the skin is not intact.

Is it normal for the skin to feel numb after applying the cream?

Yes, a mild numbing sensation is normal due to Lidocaine's anesthetic properties. However, if the area becomes overly numb or you experience irritation, stop using the product and consult your healthcare provider.

Are there any side effects from using Diclofenac Sodium 3%/Lidocaine 5% Topical Cream?

Possible side effects may include skin irritation, redness, itching, or rash. Systemic side effects are rare due to the localized nature of the application but report any severe or concerning symptoms to your healthcare provider.

Can I use this cream with other medications?

It is important to discuss all current medications you are using with your healthcare provider before starting this cream as drug interactions can occur. This includes over-the-counter drugs and herbal supplements.

Should this cream be used before or after physical activity?

You can use it both before and after physical activity, as advised by your healthcare provider, to help manage pain. However, it’s best to wait until the cream is fully absorbed before engaging in any strenuous activity.

How should I store this topical cream?

Keep the cream at room temperature, away from direct sunlight and moisture. Make sure the pump is locked or closed to prevent accidental discharge when not in use.

What should I do if I miss a dose?

If you miss a dose, apply the cream as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and return to your regular dosing schedule. Do not double doses to catch up.

Can children use this compounded formulation?

The use of this cream on children should be with the oversight of a healthcare provider. Dosage and application frequency might differ for children, so it’s important to follow a physician's advice strictly.

What do I do if I experience severe side effects?

If you experience any severe side effects or signs of an allergic reaction (such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat), seek immediate medical attention.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.