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Formulas

Diclofenac Sodium 15%/Lidocaine HCl 5%/Menthol 3% Topical Cream

This topical cream formulation combines Diclofenac Sodium at 15%, Lidocaine HCl at 5%, and Menthol at 3% in a semisolid preparation. The cream is dispensed through a pump mechanism, which allows for convenient and controlled application directly to the skin. This formulation is designed for localized treatment and aims to provide relief from pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, sprains, strains, and other musculoskeletal injuries. The inclusion of Lidocaine HCl serves as a local anesthetic to reduce immediate pain sensation, while Menthol provides a cooling effect to soothe the affected area. Diclofenac Sodium, a nonsteroidal anti-inflammatory drug (NSAID), works by reducing substances in the body that cause pain and inflammation. This combination of active ingredients is intended to offer synergistic effects for the management of pain and discomfort.

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Diclofenac Sodium
Lidocaine Hydrochloride
Menthol
Topical Cream
654eb966873cba1bbae30ebe
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Formula Information

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Our custom-compounded formulation combines Diclofenac Sodium at 15%, Lidocaine HCl at 5%, and Menthol at 3% in a topical cream base. This unique blend is specifically designed to provide targeted relief from pain and inflammation. Diclofenac Sodium, a nonsteroidal anti-inflammatory drug (NSAID), works by reducing substances in the body that cause pain and inflammation. It is commonly used for the treatment of arthritis-related conditions, offering localized relief without the systemic side effects associated with oral NSAIDs.

Lidocaine HCl, an amide-type local anesthetic, provides rapid numbing to the applied area, reducing pain by blocking the nerve signals in the body. This makes the cream particularly effective for patients experiencing neuropathic pain or for use as a supportive treatment in conditions like post-herpetic neuralgia or other localized pain syndromes.

Menthol adds a cooling sensation upon application, which helps in distracting from the pain by providing a counterirritant effect. It also promotes blood flow to the area, which can aid in the healing process. The combination of these three active ingredients in a single formulation allows for a multimodal approach to pain management, addressing pain and inflammation simultaneously while providing a soothing sensation.

The cream is dispensed in a pump mechanism, which ensures that patients can apply the medication easily and consistently, with a controlled amount of product delivered with each use. This dosage form is particularly beneficial for patients with limited dexterity or those who prefer not to touch the medication directly. The semisolid preparation is designed to be absorbed through the skin, providing localized treatment without significant systemic absorption.

This compounded formulation is ideal for patients seeking relief from localized pain and inflammation, particularly in conditions such as osteoarthritis, rheumatoid arthritis, tendinitis, or bursitis. It may also be beneficial for soft tissue injuries and certain neuropathic pain conditions. As with any medication, it is important to use this cream under the guidance of a healthcare provider, who can tailor the treatment to the individual needs of the patient.

If you have any questions about this formulation or its appropriateness for your condition, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide you with the information and support you need to make an informed decision about your pain management options.

Drug Interactions

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The topical cream formulation containing Diclofenac Sodium 15%, Lidocaine HCl 5%, and Menthol 3% is designed for localized treatment and may be used to alleviate pain, inflammation, and provide a cooling sensation to the affected area. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. Lidocaine is a local anesthetic that provides temporary relief of pain by blocking nerve signals in the body. Menthol provides a cooling sensation and can help to temporarily relieve minor pain.

When using this topical cream, it is important to consider potential drug interactions. Diclofenac, even when applied topically, may interact with other NSAIDs (such as aspirin, ibuprofen, naproxen), increasing the risk of gastrointestinal bleeding or ulcers. It is advisable to avoid using multiple NSAIDs concurrently unless directed by a healthcare provider. Patients should also be cautious if they are taking anticoagulants (like warfarin) or antiplatelet drugs (such as clopidogrel), as there may be an increased risk of bleeding. Although systemic absorption of diclofenac from topical application is lower than from oral forms, monitoring for signs of bleeding is recommended.

Lidocaine applied topically is generally considered to have a low risk of systemic drug interactions due to minimal systemic absorption. However, caution is advised when it is used in conjunction with other local anesthetics or medications that affect cardiac conduction, as there is a potential for additive systemic effects. Patients with a history of cardiac disease should use lidocaine-containing products under close supervision.

Menthol is not known to have significant drug interactions; however, it may enhance the penetration of other drugs applied topically, potentially altering their absorption and effects. Therefore, it is important to consult with a healthcare provider before combining this formulation with other topical medications.

Patients should be aware that the use of this topical cream may not be suitable for everyone, especially those with a history of allergic reactions to any of its components. It is also important to avoid applying the cream to broken or irritated skin, near the eyes, or on mucous membranes. The hands should be washed thoroughly after application unless they are the site being treated.

It is essential for both patients and prescribers to be aware of all medications and supplements the patient is currently using to avoid potential drug interactions. If there are any questions or concerns regarding the use of this topical cream or its compatibility with other medications, please reach out to us at Bayview Pharmacy for further assistance and guidance.

How Does it Work

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The Diclofenac Sodium 15%/Lidocaine HCl 5%/Menthol 3% Topical Cream is a specially compounded formulation that combines the anti-inflammatory and analgesic properties of Diclofenac Sodium with the local anesthetic effects of Lidocaine HCl and the cooling sensation provided by Menthol. This cream is designed to be applied topically to the skin, where it can provide localized relief from pain and inflammation.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the cyclooxygenase (COX) enzymes, which are involved in the synthesis of prostaglandins. Prostaglandins are lipid compounds that play a key role in the inflammation process. By reducing their production, Diclofenac Sodium effectively decreases inflammation and pain in the affected area.

Lidocaine HCl is a local anesthetic that works by blocking sodium channels in the neuronal membrane, which prevents the initiation and conduction of nerve impulses. This action results in a temporary loss of sensation in the area where the cream is applied, providing relief from pain.

Menthol provides a cooling sensation when applied to the skin by activating certain sensory receptors. This can help to distract from the pain by providing a counterirritant effect, which can be soothing and may also help to reduce the perception of pain.

The cream is formulated as a semisolid preparation, which allows for the active ingredients to be evenly distributed throughout the product. When dispensed from a pump mechanism, the cream provides a convenient and controlled method of application. This ensures that the correct dose is applied to the skin, minimizing waste and maximizing the therapeutic effects of the medication.

This topical cream is particularly useful for treating localized pain and inflammation associated with conditions such as osteoarthritis, muscle strains, or sprains. By applying the cream directly to the affected area, patients can experience targeted relief without the systemic side effects that can occur with oral medications. Additionally, the combination of Diclofenac Sodium, Lidocaine HCl, and Menthol can provide a multi-modal approach to pain management, addressing different aspects of pain and inflammation simultaneously.

For patients and prescribers interested in using this formulation, it is important to note that it should be used as directed and applied only to intact skin. It is also essential to consider any potential contraindications or interactions with other medications. If you have any questions or require further information about this compounded formulation, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you with your needs.

Other Uses

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Bayview Pharmacy's custom-formulated Diclofenac Sodium 15%/Lidocaine HCl 5%/Menthol 3% Topical Cream is primarily indicated for the relief of localized musculoskeletal pain, inflammation, and associated discomfort. However, its therapeutic potential extends beyond these typical disease states due to the actions of its individual components. Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), provides not only analgesic properties but also anti-inflammatory benefits which can be advantageous in conditions such as osteoarthritis flare-ups, tendonitis, and other inflammatory disorders localized to specific body areas.

The inclusion of Lidocaine HCl, a well-known local anesthetic, aids in the numbing of the topical region, potentially making this cream an option for temporary relief of nerve-related pain conditions such as postherpetic neuralgia or other neuropathic pain syndromes. It might also serve as a supportive therapy post minor dermal procedures, given its local anesthetic properties, to reduce immediate discomfort.

Moreover, the presence of Menthol in the formulation adds a counterirritant effect, which can induce a cooling sensation on the skin, helping to further distract from pain through stimulation of sensory nerve endings. This may be of particular use in cases of sprains or strains where the combination of cooling and analgesic properties can aid in comfort management. Also, for individuals unable to take oral pain medication, this topical application could offer an important alternative.

While this formulation has been designed with specific disease states in mind, patients or prescribers considering its use for alternative applications should do so with caution. They should ensure that the symptoms being treated are amenable to topical therapy, and that no contraindications, such as skin conditions or sensitivities, preclude its use. All potential applications of this compound cream should be discussed with a healthcare professional to ascertain suitability for the patient's unique circumstances. The convenient semisolid preparation dispensed in a pump mechanism allows for controlled dosing and targeted application, thereby optimizing the potential for therapeutic efficacy in various localized dermatological and musculoskeletal conditions.

For more personalized advice or further inquiries regarding this customized topical cream, please reach out to our knowledgeable team at Bayview Pharmacy. We are committed to providing comprehensive information and guidance to both patients and prescribers for the safe and effective use of our compounded medications.

Frequently Asked Questions

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What is Diclofenac Sodium 15%/Lidocaine HCl 5%/Menthol 3% Topical Cream?

This is a compounded formulation that combines Diclofenac Sodium, Lidocaine Hydrochloride, and Menthol in a topical cream base. It is designed to be applied to the skin to provide localized relief from pain and inflammation.

How do I use this topical cream?

Apply the cream to the affected area as directed by your healthcare provider. The pump mechanism is designed to deliver a controlled amount of medication with each use for consistent dosing.

What conditions is this cream used for?

This compounded cream is commonly used to treat localized musculoskeletal pain, joint pain, or inflammation. The combination of Diclofenac Sodium, Lidocaine, and Menthol also provides a numbing and cooling effect to soothe the affected area.

How often can I apply the cream?

The frequency of application depends on the advice of your healthcare provider, but typically, it may be applied two to three times daily. Do not exceed the recommended dose or frequency without consulting a healthcare professional.

Can this cream be used with other pain medications?

It is important to discuss with your healthcare provider before combining this cream with other pain medications, including oral or other topical products, to avoid potential interactions or side effects.

Is it normal to feel a cooling sensation after application?

Yes, the cooling sensation is due to the presence of Menthol in the formulation; it is a normal effect and contributes to the pain-relieving properties of the cream.

Should I cover the area after application of the cream?

You do not usually need to cover the treated area unless advised by your healthcare provider. Allow the cream to absorb fully into the skin before covering or dressing.

Are there any known side effects of using this cream?

Some common side effects may include skin irritation, redness, or a burning sensation at the application site. If you experience any severe reactions or if side effects persist, contact your healthcare provider.

What should I do if I miss a dose?

If you miss a dose, apply the cream as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

How should I store this topical cream?

Store the cream at room temperature away from direct sunlight and heat. Keep the pump container tightly closed when not in use. Make sure to keep it out of reach of children and pets.

What should I do in case of an overdose?

While an overdose is less likely with a topical application compared to oral medications, if you suspect you have used too much cream or have ingested it accidentally, seek immediate medical attention or contact a poison control center.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.