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Formulas

Dehydroepiandrosterone 37.5 mg Oral Capsules

Dehydroepiandrosterone (DHEA) 37.5 mg Oral Capsules are a solid dosage form consisting of two-piece gelatin or vegetarian shells. These capsules are designed to enclose a precise dose of the active ingredient, DHEA, which is a naturally occurring hormone that serves as a precursor to male and female sex hormones. The encapsulation of DHEA in this form allows for convenient and easy oral administration.

This formulation is utilized in the treatment of various disease states, including adrenal insufficiency, where the body's production of DHEA is below normal. Additionally, DHEA capsules may be used in the management of aging-related conditions, as DHEA levels typically decrease with age. They are also sometimes used for depression, osteoporosis, and systemic lupus erythematosus (SLE), although the effectiveness for these indications may vary and should be evaluated by a healthcare provider.

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Formula Information

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Dehydroepiandrosterone (DHEA) 37.5 mg Oral Capsules are a solid dosage form consisting of two halves, either gelatin-based or made from vegetarian alternatives, that encapsulate the active pharmaceutical ingredient. These capsules are designed to be easily swallowed, ensuring patient compliance, and provide a precise dose of DHEA, which is critical for maintaining the accuracy of therapy. DHEA is an endogenous steroid hormone, which serves as a precursor to androgens and estrogens in the human body. It is synthesized by the adrenal glands, gonads, and the brain.

DHEA supplementation has been explored for a variety of clinical applications due to its role in the production of sex hormones. It is often used in the treatment of conditions that involve a deficiency or imbalance of steroid hormones. For instance, DHEA has been studied for its potential benefits in managing adrenal insufficiency, where the body's production of steroids, including DHEA, is inadequate. Additionally, it has been investigated for its possible role in improving aging-related conditions, such as decreased bone density, muscle strength, and sexual function, as well as its potential to impact mood and cognition.

While DHEA is available as a dietary supplement in some jurisdictions, its use as a medication should be guided by a healthcare professional. It is important to note that the efficacy and safety of DHEA supplementation can vary among individuals, and its use may be contraindicated in certain conditions, such as hormone-sensitive cancers. Therefore, prescribers should evaluate the potential benefits and risks of DHEA therapy on a case-by-case basis, considering the patient's medical history, current medications, and overall health status.

Patients should be counseled on the proper use of DHEA capsules, including adherence to prescribed dosages and the importance of regular monitoring by their healthcare provider. Potential side effects, such as oily skin, acne, hair loss, increased facial hair in women, or changes in menstrual cycle, should be discussed, and patients should be instructed to report any adverse effects or concerns promptly to their healthcare provider.

For more detailed information on the formulation, potential uses, contraindications, and guidance on the administration of Dehydroepiandrosterone 37.5 mg Oral Capsules, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing comprehensive support to both patients and prescribers to ensure the safe and effective use of this medication.

Drug Interactions

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Dehydroepiandrosterone (DHEA) is an endogenous steroid hormone that serves as a precursor to androgens and estrogens, which are vital for a wide range of physiological functions. DHEA supplementation is used for conditions such as adrenal insufficiency, depression, induction of labor, and systemic lupus erythematosus, among others. However, it is important to consider potential drug interactions when prescribing or taking DHEA supplements.

One significant interaction is with medications that are metabolized by the liver. DHEA is metabolized by cytochrome P450 enzymes, specifically CYP3A4. Drugs that are also metabolized by CYP3A4 may have altered effects when taken concurrently with DHEA. For example, DHEA may increase the metabolism of some benzodiazepines, calcium channel blockers, and certain statins, potentially reducing their effectiveness. Conversely, drugs that inhibit CYP3A4 could lead to increased levels of DHEA, possibly increasing the risk of side effects such as acne, hair loss, or hirsutism.

Additionally, DHEA may interact with hormone therapies, including estrogen and testosterone, as it can affect hormone levels in the body. Patients using hormone replacement therapy should be closely monitored for signs of hormonal imbalance when starting or adjusting DHEA supplementation. The use of DHEA with other supplements that have hormonal activity, such as soy products, wild yam, or tribulus, may also alter the intended hormonal effects and should be approached with caution.

Patients on anticoagulant or antiplatelet medications should be aware that DHEA may have a mild anticoagulant effect, which could potentially increase the risk of bleeding when taken together with these medications. Close monitoring of coagulation parameters is advised when initiating or changing the dose of DHEA in patients taking warfarin, aspirin, or other blood thinners.

Individuals with diabetes or those taking medications for blood sugar control should note that DHEA may affect insulin sensitivity and glucose metabolism. This could necessitate adjustments in antidiabetic medication dosages to maintain optimal glycemic control. Regular monitoring of blood glucose levels is recommended for patients taking DHEA in conjunction with antidiabetic drugs.

It is also important to consider the potential for DHEA to interact with psychiatric medications. Since DHEA can influence mood and behavior, it may alter the effects of antidepressants, antipsychotics, and anxiolytics. Patients with mental health conditions should be closely supervised by their healthcare provider when using DHEA supplements.

Lastly, DHEA may interact with other dietary supplements and over-the-counter medications. For instance, it may enhance the effects of certain herbs and supplements known to have anti-inflammatory, estrogenic, or androgenic properties. Patients should inform their healthcare provider of all medications, supplements, and herbs they are taking to avoid unintended interactions.

In conclusion, while DHEA can be beneficial for certain conditions, it is crucial to be aware of its potential interactions with other drugs and supplements. Healthcare providers should review a patient's complete medication list, including prescription drugs, over-the-counter medications, and dietary supplements, before recommending DHEA. Patients should be monitored for side effects and therapeutic efficacy, and dosages of other medications may need to be adjusted accordingly. If you have any questions or concerns about the use of DHEA 37.5 mg Oral Capsules or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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Dehydroepiandrosterone (DHEA) is a naturally occurring hormone produced by the adrenal glands, gonads, and brain. It serves as a precursor to male and female sex hormones, including testosterone and estrogen. As a medication, DHEA is used in the form of oral capsules to supplement individuals who have low levels of this hormone, which can occur due to aging, adrenal insufficiency, or other medical conditions. The 37.5 mg dosage of DHEA in these capsules is carefully measured to provide a consistent and precise amount of the active ingredient for therapeutic use.

The oral capsules are solid dosage forms that consist of two halves of a shell made from either gelatin or a vegetarian alternative. These shells are filled with the powdered form of DHEA and then sealed together. This design allows for the medication to be ingested easily and to dissolve at a controlled rate in the digestive system, ensuring that the active ingredient is released and absorbed into the bloodstream. The encapsulation process also protects the DHEA from degradation by environmental factors such as light and moisture, thereby maintaining its potency and efficacy.

In terms of treating disease states, DHEA supplementation has been explored for a variety of conditions. It is most commonly used to improve symptoms associated with adrenal insufficiency, where the adrenal glands do not produce adequate amounts of hormones. Additionally, DHEA has been studied for its potential benefits in conditions such as systemic lupus erythematosus (SLE), depression, osteoporosis, and sexual dysfunction, although its effectiveness for these conditions may vary and more research is needed. It is thought that by increasing the levels of DHEA, and consequently the levels of sex hormones derived from it, the body may be better able to regulate various physiological processes that are influenced by these hormones.

It is important for patients and prescribers to understand that while DHEA supplementation can be beneficial for certain individuals, it should be used under the guidance of a healthcare professional. Monitoring of hormone levels and assessment of symptoms are necessary to ensure the appropriate use of this medication. Additionally, DHEA may interact with other medications and is not suitable for everyone, particularly those with hormone-sensitive conditions such as certain cancers.

If you have any questions about the use of Dehydroepiandrosterone 37.5 mg Oral Capsules or would like more information about how this formulation works, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the knowledge and support you need to make informed decisions about your health and medication regimen.

Other Uses

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Dehydroepiandrosterone (DHEA) is a naturally occurring hormone that is predominantly produced by the adrenal glands. While it is commonly administered to treat a variety of conditions related to hormone levels, such as adrenal insufficiency, depression related to hormone imbalance, and systemic lupus erythematosus, research has suggested several other potential uses for DHEA. These include but are not limited to the improvement of aging skin, increasing bone density, aiding in weight loss, and enhancing mood and sexual function. Aging individuals sometimes use DHEA supplements with the belief that it can help counteract a decrease in the natural DHEA levels as they age, potentially improving well-being, cognitive function, and body composition.

Furthermore, some studies indicate DHEA supplementation may have a beneficial effect on certain conditions like osteoporosis, vaginal atrophy, and erectile dysfunction, supporting the use of DHEA in these areas. However, it's important to note that the evidence for these uses is still emerging and considerable variability exists in terms of how individuals respond to DHEA supplementation. The precise mechanisms by which DHEA exerts its effects in these areas are still being elucidated, but it is thought to involve the hormone's ability to be metabolized into both androgens and estrogens, thus influencing a wide array of physiological processes.

As with any supplement, risks, and benefits should be weighed, and patients considering DHEA should consult with a healthcare provider before starting therapy. It is especially important for individuals with a history of hormone-sensitive conditions, such as breast, uterine, or prostate cancer, to seek medical advice due to the hormone-like effects of DHEA. Frequent monitoring may be recommended in some populations, particularly when high doses are used or for long-term therapy. If you have questions or require personalized advice related to DHEA supplementation for conditions other than those mentioned above, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is available to provide you with the information and guidance needed to make an informed decision about using DHEA 37.5 mg oral capsules.

Frequently Asked Questions

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What is Dehydroepiandrosterone (DHEA) 37.5 mg Oral Capsule?

Dehydroepiandrosterone, or DHEA, is a hormone produced by the body's adrenal glands. The 37.5 mg oral capsule is a supplemental form used to deliver a precise dose of DHEA in situations where the body may not produce adequate amounts.

How should I take Dehydroepiandrosterone 37.5 mg Oral Capsules?

You should take this medication exactly as prescribed by your healthcare provider. The capsule should be swallowed whole with a glass of water, and it can be taken with or without food.

What are the benefits of using a capsule form for DHEA supplementation?

Capsules provide an accurate dose of the active ingredient, ensuring consistency in your supplementation regimen. Additionally, they are easy to swallow and may reduce the likelihood of experiencing a bitter taste.

Are the capsules made from gelatin or a vegetarian alternative?

The capsules can be made from either gelatin or a vegetarian-friendly material. You should check with your pharmacist to ensure you receive the type that aligns with your dietary preferences.

Can I open the capsule and mix the contents with food or drink?

Generally, the capsule should be taken whole to ensure proper dosage and effectiveness. Opening the capsule might alter the release and absorption of the medication. Consult with your healthcare provider before altering how you take your medication.

How should I store Dehydroepiandrosterone 37.5 mg Oral Capsules?

Store the capsules at room temperature, away from direct light, moisture, and heat. Keep the medication out of reach of children and pets.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for the missed one. Consult your healthcare provider for more guidance on missed doses.

Can I experience any side effects from taking DHEA 37.5 mg Oral Capsules?

As with any supplement, side effects are possible. These can include oily skin, acne, hair loss, stomach upset, high blood pressure, and changes in menstrual cycle. If you experience adverse effects, contact your healthcare provider immediately.

Is DHEA supplementation appropriate for everyone?

No, DHEA supplementation is not suitable for everyone. It should not be used by individuals with certain health conditions, those who are pregnant or breastfeeding, or those under the age of 18 unless prescribed by a healthcare professional. Always consult with your healthcare provider before starting any new supplements.

Do I need a prescription to obtain Dehydroepiandrosterone 37.5 mg Oral Capsules?

Yes, in many countries including the United States, DHEA is considered a controlled substance and requires a prescription. Please check with your local laws and regulations regarding the purchase and use of DHEA supplements.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.