Our custom-compounded formulation combines Dehydroepiandrosterone (DHEA) 10 mg, Estradiol 0.6 mg, Estriol 2.4 mg, and Testosterone 1 mg into a 0.25 mL topical cream. This unique blend of hormones is specifically designed to address various conditions related to hormonal imbalances or deficiencies. The cream is a semisolid preparation that is dispensed through a pump mechanism, which ensures a convenient, controlled, and consistent application to the skin. This method of delivery is particularly beneficial for patients seeking localized treatment with minimal systemic absorption, although some systemic uptake is expected with these hormones.

DHEA is a precursor to both estrogen and testosterone and is often used to improve skin health and potentially support adrenal function. Estradiol and Estriol are forms of estrogen that can alleviate symptoms of menopause, such as hot flashes, vaginal dryness, and bone loss. Testosterone in the formulation can help improve libido, mood, and muscle mass. The combination of these hormones in one cream allows for a synergistic approach to treatment, which may be more convenient and effective than using separate products.

This hormone therapy cream is typically prescribed for conditions such as menopausal symptoms, androgen deficiency, and certain cases of osteoporosis. It may also be used for improving skin elasticity and texture, as well as for overall well-being in patients with hormone imbalances. The precise dosing and combination of hormones are tailored to the individual needs of the patient, based on their hormonal profile and clinical symptoms.

It is important for both patients and prescribers to understand that hormone replacement therapy (HRT) should be used with caution and under the supervision of a healthcare professional. Regular monitoring of hormone levels and clinical response is essential to ensure safety and efficacy. Patients should be aware of potential side effects, which can include skin irritation at the site of application, systemic hormonal effects, and others depending on the individual's health status and other medications they may be taking.

As compounding pharmacists at Bayview Pharmacy, we are committed to providing high-quality, personalized medications to meet the specific needs of our patients. If you have any questions about this formulation or its appropriateness for your condition, please do not hesitate to reach out to us. We are here to support both patients and healthcare providers in the safe and effective use of compounded hormone therapies.

The formulation you have described contains a combination of hormones: dehydroepiandrosterone (DHEA), estradiol, estriol, and testosterone, which are intended for topical application. When considering drug interactions for this formulation, it is important to note that each of these hormones can interact with a variety of medications, supplements, and even certain foods, potentially altering their effects or increasing the risk of side effects.

Dehydroepiandrosterone (DHEA) is a hormone that can affect the levels of other hormones in the body. It may interact with medications for mental health conditions such as depression and anxiety, as well as with hormone therapies, including estrogen and testosterone. Patients should be cautious when using other topical medications or products on the same area of skin where the DHEA-containing cream is applied, as this could alter the absorption of either product.

Estradiol and estriol are forms of estrogen, and they can interact with thyroid hormone replacement therapies, anticoagulants like warfarin, and certain cancer treatments. Estrogens can also reduce the effectiveness of aromatase inhibitors, which are used in the treatment of certain types of breast cancer. Additionally, patients using medications for diabetes should be monitored as estrogens can affect blood sugar levels.

Testosterone can interact with corticosteroids and may increase the risk of edema, especially in patients with liver or heart conditions. It can also affect the action of anticoagulants, potentially increasing the risk of bleeding. Testosterone may also alter the effects of medications for diabetes and should be used with caution in patients receiving insulin or oral diabetes medications.

It is also important to consider the impact of over-the-counter medications, herbal supplements, and certain foods. For example, grapefruit juice can affect the metabolism of estradiol and should be avoided. Patients should inform their healthcare provider of all medications, supplements, and herbal products they are using before starting treatment with this hormone combination cream.

This topical hormone combination cream is used to treat various conditions related to hormone deficiencies or imbalances, such as menopausal symptoms, certain types of hair loss, and skin aging. DHEA can improve skin hydration and thickness, while estradiol and estriol can alleviate symptoms of estrogen deficiency such as hot flashes and vaginal dryness. Testosterone can be beneficial in certain conditions of testosterone deficiency, contributing to an overall balance of hormones in the body.

Patients and prescribers should be aware that the use of this formulation requires careful monitoring, especially in patients with a history of hormone-sensitive cancers, liver disease, or cardiovascular disease. It is essential to follow the prescribed dosage and application instructions to minimize the risk of systemic absorption and potential side effects. If you have any questions or concerns regarding this formulation or its interactions with other medications, please reach out to us at Bayview Pharmacy for further assistance.

The formulation of Dehydroepiandrosterone (DHEA) 10 mg/Estradiol 0.6 mg/Estriol 2.4 mg/Testosterone 1 mg per 0.25 mL Topical Cream is a compounded medication designed to deliver a combination of hormones directly through the skin. This semisolid preparation is dispensed in a pump mechanism, which allows for precise dosing and easy application. The cream base facilitates the absorption of the active ingredients into the skin, where they can exert their effects either locally or systemically after being absorbed into the bloodstream.

DHEA is a hormone produced by the adrenal glands, which serves as a precursor to other sex hormones, including estrogen and testosterone. Supplementation with DHEA can help to restore levels in the body that may decrease with age or due to certain health conditions. Estradiol and estriol are forms of estrogen, a female sex hormone that regulates many processes in the body. Estradiol is the most potent form of estrogen and is often used to treat symptoms of menopause, such as hot flashes and vaginal dryness. Estriol is a weaker estrogen, which is thought to offer benefits without the same level of risk associated with stronger estrogens. Testosterone, while typically considered a male hormone, plays a crucial role in female health as well, influencing libido, energy levels, and mood.

This combination cream is often used in hormone replacement therapy (HRT) for menopausal symptoms, as it can help to balance hormone levels and alleviate symptoms. The inclusion of both estrogens and testosterone can address a broad range of symptoms, while the addition of DHEA supports the body's natural hormone production. The topical route of administration helps to minimize first-pass metabolism by the liver, potentially reducing systemic side effects and risks associated with oral hormone therapies.

For patients, it is important to apply the cream as directed by a healthcare provider, typically to a thin-skinned area for better absorption, such as the inner forearm. The pump mechanism ensures that each dose contains the same amount of hormones, providing consistency in dosing. For prescribers, it is crucial to tailor the hormone combination to the individual needs of the patient, monitoring their response to therapy and adjusting the formulation as necessary.

As compounding pharmacists at Bayview Pharmacy, we are available to answer any questions regarding this formulation. We can provide guidance on the appropriate use of this medication, potential side effects, and the benefits of a customized hormone therapy approach. Please reach out to us for further information or with any specific inquiries you may have.

The compounded formulation of Dehydroepiandrosterone (DHEA) 10 mg, Estradiol 0.6 mg, Estriol 2.4 mg, and Testosterone 1 mg per 0.25 mL in a topical cream offers a synergistic blend of hormones that could potentially be used in a variety of clinical applications beyond strictly menopausal symptoms and hormone replacement therapy. While the primary indication is to address hormonal deficiencies and related symptoms in perimenopausal and menopausal women, such as hot flashes, vaginal atrophy, and osteoporosis prevention, there may be additional therapeutic benefits based on the individual components of this formulation.

DHEA, being a precursor to both estrogen and testosterone, has been explored for its potential use in improving mood, boosting energy levels, enhancing libido, and supporting adrenal gland function. Moreover, some studies have investigated its role in cognitive health and its potential anti-aging effects. Estradiol and estriol, being forms of estrogen, could be beneficial in improving skin elasticity, texture, and moisture, potentially aiding in the management of aging skin or dermatological conditions influenced by hormonal changes. Testosterone, even at low doses, may contribute to muscle strength, bone density, sexual function, and general well-being.

It's important to recognize that the use of this compound cream for indications other than menopausal symptom relief should be carefully considered and closely monitored by a healthcare professional. The balance and interactions between hormones are complex, and individual needs can vary significantly. Off-label uses of hormone therapy should be based on clinical evidence, and prescribers should evaluate the risks and benefits for each patient. Adjustments in dosage or formulation may be necessary to optimize therapy for conditions unrelated to menopause.

Patients and prescribers considering this formulation for other uses should proceed with caution and regularly assess treatment efficacy and development of any side effects. With any compounded medication, it is critical to work with a knowledgeable compounding pharmacist who can guide appropriate use and ensure medications are made according to high-quality standards. If you have any questions or would like to discuss potential uses of this formulation, please reach out to us at Bayview Pharmacy. Our team is committed to providing in-depth information and personalized support to optimize patient care.