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Cyclobenzaprine HCl 3%/Ketoprofen 10%/Lidocaine HCl 5% Topical Gel

This formulation is a combination of Cyclobenzaprine HCl 3%, Ketoprofen 10%, and Lidocaine HCl 5% in a topical gel form. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The Cyclobenzaprine HCl acts as a muscle relaxant, reducing muscle spasms and providing relief from associated pain. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain in the body. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This combination is commonly used to treat conditions such as muscle sprains, strains, arthritis, and nerve pain.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Cyclobenzaprine HCl 3%, Ketoprofen 10%, and Lidocaine HCl 5%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency of the formulation ensures that the active ingredients are absorbed effectively into the targeted area.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is commonly used to treat muscle spasms and to relieve pain and discomfort caused by strains, sprains, and other muscle injuries. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. It is used to treat mild to moderate pain, or inflammation caused by arthritis. The third active ingredient, Lidocaine HCl, is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It is used on the skin to stop itching and pain from certain skin conditions (e.g., scrapes, minor burns, eczema, insect bites) and to treat minor discomfort and itching caused by hemorrhoids and certain other problems of the genital/anal area.

This combination of active ingredients makes the formulation particularly effective for treating conditions that involve muscle pain, inflammation, and a need for local anesthesia. The gel form allows for targeted treatment, as it can be applied directly to the area of discomfort. This can provide more effective relief than oral medications, which must be absorbed through the digestive system before they can take effect. Furthermore, because the medication is applied topically, it is less likely to cause systemic side effects.

It is important to use this medication as directed by your healthcare provider. Do not apply more often, or for a longer time than directed. The dosage is based on your medical condition and response to therapy. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. If you have any questions about the use of this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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This formulation contains three active ingredients: Cyclobenzaprine HCl, Ketoprofen, and Lidocaine HCl. Each of these ingredients can interact with other medications, potentially altering their effects or increasing the risk of adverse reactions.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It can interact with monoamine oxidase inhibitors (MAOIs), increasing the risk of serious side effects such as high fever, severe headache, stiff muscles, and confusion. It can also interact with other central nervous system depressants, including alcohol, barbiturates, benzodiazepines, and narcotics, potentially leading to increased sedation and respiratory depression.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. It can interact with blood thinners, such as warfarin, increasing the risk of bleeding. It can also interact with other NSAIDs, corticosteroids, and alcohol, increasing the risk of gastrointestinal bleeding. Additionally, it can interact with angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), or diuretics, potentially reducing their effectiveness or increasing the risk of kidney damage.

Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body. It can interact with other local anesthetics or medications that are similar to lidocaine, potentially leading to increased systemic absorption and toxicity. It can also interact with antiarrhythmic drugs, such as mexiletine, potentially leading to additive cardiac effects.

This formulation is designed to be applied topically, which can reduce the risk of systemic drug interactions. However, systemic absorption can still occur, especially if the formulation is applied over large areas of skin, on broken or inflamed skin, or under occlusive dressings. Therefore, it's important to use this formulation as directed by your healthcare provider and to inform them of all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.

This formulation is used to treat various disease states, including muscle spasms, inflammation, and pain. Cyclobenzaprine HCl relaxes muscles to reduce spasms, Ketoprofen reduces inflammation and pain, and Lidocaine HCl numbs the skin to provide local pain relief. By combining these three active ingredients in a single formulation, it can provide targeted treatment for a variety of conditions.

If you have any questions about this formulation or its potential drug interactions, please don't hesitate to reach out to us. We are here to help ensure that you can use this formulation safely and effectively.

How Does it Work

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This formulation combines three active ingredients: Cyclobenzaprine HCl, Ketoprofen, and Lidocaine HCl, each with a unique mechanism of action to provide relief from pain and inflammation. The gel is designed to be applied topically, directly to the area of discomfort, allowing for targeted treatment.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is particularly effective in treating muscle spasms and associated pain. When applied topically, it can provide localized relief without the systemic side effects often associated with oral administration.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is commonly used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, sprains, and other injuries. In this formulation, Ketoprofen is applied directly to the skin, allowing it to penetrate the skin and exert its anti-inflammatory and analgesic effects on the underlying tissues.

Lidocaine HCl is a local anesthetic that works by causing temporary numbness in the area where it is applied. It works by blocking nerve signals in your body and is often used to relieve pain and discomfort caused by skin irritations, sore throats, sunburn, teething pain, vaginal or rectal irritation, ingrown toenails, hemorrhoids, and many other sources of minor pain on the surface of the body. In this formulation, Lidocaine HCl provides immediate, localized pain relief.

The gel formulation allows for easy and precise application of the medication. The semisolid consistency ensures that the medication stays where it is applied, providing targeted relief. The pump mechanism allows for controlled dispensing, reducing the risk of applying too much or too little medication.

This formulation is designed to treat a variety of disease states that involve pain and inflammation. It can be particularly beneficial for patients with conditions such as arthritis, muscle spasms, and injuries that result in pain and inflammation. By providing targeted, localized treatment, this formulation can provide relief without the systemic side effects often associated with oral medications.

If you have any questions about this formulation, its ingredients, or how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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The combination formulation of Cyclobenzaprine HCl 3%/Ketoprofen 10%/Lidocaine HCl 5% Topical Gel is primarily meant for providing relief from pain, inflammation, and muscle spasms, especially in conditions like arthritis, fibromyalgia, and post-surgery healing. Additionally, this formulation can also be used for conditions unrelated to these disease states due to the distinct properties of each of the ingredients.

Cyclobenzaprine, a muscle relaxant, is effective in treating muscle spasms related to acute musculoskeletal conditions. It's also beneficial in managing tension-type headaches and neck pain. Ketoprofen, an NSAID, helps mitigate pain from various conditions like sprain, bursitis, and tendonitis. It can be a useful adjuvant in managing post-operative pain or pain related to minor surgery or dental extraction. Lidocaine, a local anesthetic, has a general application in managing discomfort and pain by numbing the specific area. It is commonly used in conditions such as sunburns, insect bites, poison ivy, and minor cuts or burns.

Furthermore, some patients have reported relief from neuropathic pain conditions, such as diabetic neuropathy and postherpetic neuralgia, when using this topical gel. It has also been applied to treat back pain, tendinitis, and other localized forms of pain. The ease of application through its semisolid gel-like consistency can limit systemic exposure, particularly useful for those with co-existing health conditions that could be exacerbated by systemic analgesics or anti-inflammatory drugs. Such patients include the elderly or those with conditions like kidney, heart, or liver ailments where systemic NSAIDS are generally contraindicated.

At the same time, prescribers should be aware that the use of such multi-component topical analgesics requires attention to patients' specific needs, problems, and individual conditions to determine suitability. Potential allergies to any of the ingredients or previous sensitivity reactions should be noted before prescribing.

If you still have queries regarding this formulation, do not hesitate to reach out to us at Bayview Pharmacy. We are a team of end-to-end solution providers, with compounding pharmacists able to provide deep insights into the right applications of this and other formulations.

Frequently Asked Questions

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What is Cyclobenzaprine HCl 3%/Ketoprofen 10%/Lidocaine HCl 5% Topical Gel?

This is a compounded formulation of three active ingredients - Cyclobenzaprine Hydrochloride (3%), Ketoprofen (10%), and Lidocaine Hydrochloride (5%). It is dispensed as a semisolid gel through a pump mechanism for easy and precise application on the skin.

How do I use this medication?

This gel is designed to be applied topically on your skin, in the area needing treatment. Use the pump mechanism to dispense the accurate amount of gel. Always follow your doctor's instructions regarding usage.

What are the active ingredients in this gel?

This topical gel contains Cyclobenzaprine Hydrochloride, a muscle relaxant; Lidocaine Hydrochloride, a local anesthetic; and Ketoprofen, an anti-inflammatory drug.

What is the role of the pump mechanism?

The pump mechanism allows easy dispensing of the medication from its container and facilitates precise application on the skin as it dispenses a defined amount of gel with each pump.

Is this compounded formulation safe for all skin types?

This compounded formulation is designed to be safe for all skin types. However, each individual may react differently. If you experience any skin irritations or other unwanted effects, stop using the product and consult your doctor immediately.

What is the purpose of the gel consistency?

The gel-like consistency helps in the easy application and penetration of the active ingredients into the skin for targeted treatment.

Should I rub the gel into my skin?

Yes, after applying the gel to the affected area, you should gently rub it into your skin for effective absorption of the active ingredients.

Can I use the topical gel on open wounds?

No, you should not use this gel, or any other topical medication, on open, bleeding wounds or unhealed skin without consulting with your healthcare provider first.

Can I cover the treated area after application?

It is best not to cover the area where the gel is applied unless advised by a healthcare provider. Covering the area may affect the absorption rate of the medication.

Can I use other medications with this topical gel?

You should always inform your doctor about all other medications you are taking, including over-the-counter drugs, to avoid potential drug interactions. Never start a new medication without consulting your healthcare provider.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.