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Cyclobenzaprine HCl 2%/Ketoprofen 15% Transdermal Gel

The Cyclobenzaprine HCl 2%/Ketoprofen 15% Transdermal Gel is a semisolid formulation dispensed through a pump mechanism. This formulation is designed for easy and precise application on the skin, allowing for targeted treatment or absorption of the active ingredients. The gel-like consistency ensures a smooth and comfortable application process.

This formulation combines the muscle relaxant properties of Cyclobenzaprine HCl and the anti-inflammatory effects of Ketoprofen. It is primarily used to treat conditions such as muscle spasms, inflammation, and pain associated with musculoskeletal conditions like arthritis, bursitis, and tendonitis. The transdermal delivery allows for direct application to the affected area, providing localized relief while minimizing systemic side effects.

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Cyclobenzaprine Hydrochloride
Ketoprofen
Topical Gel
653eac237729bff1613750fd
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Formula Information

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This formulation combines two active ingredients, Cyclobenzaprine HCl and Ketoprofen, in a transdermal gel. Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. The combination of these two medications in a 2%/15% ratio provides both muscle relaxation and anti-inflammatory effects.

The transdermal gel is a semisolid formulation that is dispensed through a pump mechanism. This allows for easy and precise application on the skin. The gel-like consistency ensures that the medication is absorbed directly into the targeted area, providing localized treatment. This method of delivery can be particularly beneficial for patients who have difficulty swallowing pills or who need to avoid systemic side effects often associated with oral medications.

This formulation is typically used to treat conditions such as muscle spasms, inflammation, and pain associated with conditions like arthritis, bursitis, and tendonitis. By applying the gel directly to the affected area, patients can experience relief from pain and inflammation, as well as improved muscle function. It's important to note that while this formulation can help manage symptoms, it does not cure the underlying conditions.

As with any medication, it's important for patients and prescribers to be aware of potential side effects and interactions. Common side effects may include skin irritation at the application site. Serious side effects are rare but can include stomach bleeding, kidney problems, or heart attack. Patients should inform their healthcare provider of all medications they are currently taking to avoid potential interactions.

At Bayview Pharmacy, we are committed to providing high-quality, personalized medications to meet the unique needs of each patient. Our team of compounding pharmacists is always available to answer any questions or concerns you may have about this formulation. Please don't hesitate to reach out to us.

Drug Interactions

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The formulation of Cyclobenzaprine HCl 2%/Ketoprofen 15% Transdermal Gel is designed to provide targeted treatment for muscle spasms and inflammation. Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. Together, they provide a potent combination for the treatment of muscle spasms and inflammation.

However, it's important to be aware of potential drug interactions. Cyclobenzaprine HCl can interact with other medications that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), other muscle relaxants, or antihistamines (such as cetirizine, diphenhydramine). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Ketoprofen can interact with other NSAIDs (including aspirin and ibuprofen), blood thinners (such as warfarin), lithium, methotrexate, corticosteroids (such as prednisone), and medications for high blood pressure or heart conditions (such as ACE inhibitors, ARBs, beta-blockers). It can also interact with certain dietary supplements, such as fish oil and vitamin E. Additionally, ketoprofen can increase your risk of serious stomach or intestinal problems (including bleeding or ulcers), especially if used long term, in high doses, or if you are older or in poor health. These risks can be increased if ketoprofen is used with alcohol or certain other drugs (such as corticosteroids or blood thinners).

It's crucial to inform your doctor or pharmacist of all the products you use, including prescription drugs, nonprescription drugs, and herbal products, before starting treatment with this product. Also, check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.

If you have any questions about the potential interactions of Cyclobenzaprine HCl 2%/Ketoprofen 15% Transdermal Gel with other medications or substances, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information you need to use this formulation safely and effectively.

How Does it Work

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The Cyclobenzaprine HCl 2%/Ketoprofen 15% Transdermal Gel is a unique formulation that combines the muscle relaxant properties of Cyclobenzaprine HCl and the anti-inflammatory and analgesic effects of Ketoprofen. This combination is designed to provide targeted relief from pain and inflammation associated with various musculoskeletal conditions.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is particularly effective in treating muscle spasms and associated pain. When applied topically in a gel form, Cyclobenzaprine HCl can directly target the affected area, providing localized relief without the systemic side effects often associated with oral administration.

Ketoprofen, on the other hand, is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is commonly used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, sprains, and other injuries. When combined with Cyclobenzaprine HCl in a transdermal gel, Ketoprofen can provide enhanced pain relief and reduce inflammation in the targeted area.

The transdermal gel formulation allows for the active ingredients to be absorbed directly through the skin and into the affected area. This targeted approach can provide faster and more effective relief compared to oral medications, which must first pass through the digestive system. The gel is dispensed through a pump mechanism, which allows for easy and precise application. This can be particularly beneficial for patients who have difficulty swallowing pills or who prefer a non-invasive method of medication administration.

It's important to note that while this formulation can provide significant relief from pain and inflammation, it is not a cure for the underlying condition. It should be used as part of a comprehensive treatment plan, which may include physical therapy, exercise, and other medications. As with any medication, it's important to use this formulation as directed by your healthcare provider to ensure the best possible outcome.

If you have any questions about the Cyclobenzaprine HCl 2%/Ketoprofen 15% Transdermal Gel, or if you would like more information about how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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Outside of the commonly prescribed purposes, Cyclobenzaprine HCl 2%/Ketoprofen 15% Transdermal Gel could potentially be used for other conditions. The medication is typically indicated for managing muscular pain or discomfort alongside inflammation where easy and targeted application is desired. However, it may also be employed in instances of sports-related strains or sprains, tendonitis, bursitis, and other musculoskeletal conditions involving muscle spasms and inflammation. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID), which can be useful in reducing inflammation, pain, and fever, while Cyclobenzaprine is a muscle relaxant aiding in alleviating muscle spasms. Together, they form a powerful combination therapy that targets various components of acute musculoskeletal pain.

Another potential use could be for individuals experiencing symptoms of fibromyalgia, given the cyclobenzaprine's effectiveness in managing some of the key symptoms of this condition such as muscular pain and difficulty sleeping. This formulation can offer targeted relief with fewer systemic side effects than orally administered drugs. Additionally, the transdermally applied combination could be considered for certain types of neuropathic pain, including postherpetic neuralgia or diabetic neuropathy, with the rationale that NSAIDs and muscle relaxants like ketoprofen and cyclobenzaprine can help relieve these issues.

Though these additional uses could fall within the therapeutic range of the compounds in question, all off-label use should be cautiously assessed on a case-by-case basis due to the complex nature of drug interactions and the unique biochemistry of individual patients. Please note that while we strive to provide accurate and in-depth information, this does not constitute medical advice and should not be used as a substitute for professional medical guidance. Always discuss your symptoms and treatment options with a healthcare provider. Please reach out to us at Bayview Pharmacy with any further questions concerning this formulation or its potential uses.

Frequently Asked Questions

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What is this compounded formulation of Cyclobenzaprine HCl 2%/Ketoprofen 15% Transdermal Gel?

This is a semisolid formulation that is dispensed using a pump mechanism. It allows for easy, precise application on the skin for targeted absorption of the active ingredients, Cyclobenzaprine HCl and Ketoprofen. The gel-like consistency makes it quickly absorbed into the skin for faster effects.

How is this formulation administered?

This formulation is administered topically, meaning it is applied directly to the skin. The pump mechanism allows for easy application and a precise dosage.

What is the purpose of Cyclobenzaprine HCl in the formulation?

Cyclobenzaprine HCl is a muscle relaxant, often used to relieve skeletal muscle spasms and associated pain in musculoskeletal conditions.

What role does Ketoprofen play in the formulation?

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.

What kind of conditions can be treated with this compounded formulation?

This compounded formulation is often used to treat conditions that involve acute pain related to muscle spasms and inflammation such as strains, sprains, and other muscle injuries.

Is this formulation safe to use on any part of the body?

Typically, this transdermal gel is safe for use on most parts of the body, but it should be kept away from sensitive areas such as the eyes and mucous membranes. Always follow the specific instructions provided by your healthcare professional or pharmacist.

Does this formulation have any side effects?

As with any medication, it may have potential side effects. These can include skin irritation at the site of application. Always discuss any potential side effects with your healthcare provider.

How should this formulation be stored?

This gel should be stored at room temperature, away from moisture and heat. Do not allow it to freeze.

Can I use other medications while using this formulation?

Before starting any new medication, always inform your healthcare professional of all the medications you are currently taking, including this formulation, to prevent any potential drug interactions.

Where should this formulation be applied?

This formulation should be applied at the direct site of pain or inflammation for targeted treatment. Avoid application on broken or irritated skin.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.