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Cyclobenzaprine HCl 2%/Ketoprofen 10%/Lidocaine HCl 10% Topical Gel

This formulation is a combination of Cyclobenzaprine HCl 2%, Ketoprofen 10%, and Lidocaine HCl 10% in a topical gel form. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The formulation is primarily used to treat various disease states. Cyclobenzaprine HCl is a muscle relaxant that helps to relieve muscle spasms, while Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, swelling, and inflammation. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This combination is often used to manage conditions such as musculoskeletal pain, arthritis, neuropathic pain, and other related conditions.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Cyclobenzaprine HCl 2%, Ketoprofen 10%, and Lidocaine HCl 10%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency of the formulation ensures that the active ingredients are absorbed effectively into the targeted area.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is commonly used to treat muscle spasms and to relieve pain and discomfort caused by strains, sprains, and other muscle injuries. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. It is used to treat mild to moderate pain, or inflammation caused by arthritis. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It is used to relieve pain and discomfort from a wide variety of skin conditions, or to numb the skin before certain procedures.

Together, these three active ingredients work synergistically to provide relief from pain and inflammation. The topical application allows for targeted treatment, reducing systemic exposure and potential side effects. This makes it an excellent option for patients who may be unable to tolerate oral medications or for those who prefer a non-invasive method of treatment.

As with any medication, it is important to use this formulation as directed by your healthcare provider. Avoid contact with eyes, nose, mouth, and other sensitive areas. If irritation or adverse reactions occur, discontinue use and consult your healthcare provider. It is also important to inform your healthcare provider of all medications you are currently taking, as there may be potential interactions.

If you have any questions about this formulation, or if you would like more information, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to assist you.

Drug Interactions

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This formulation contains three active ingredients: Cyclobenzaprine HCl, Ketoprofen, and Lidocaine HCl. Each of these ingredients can interact with other medications, potentially altering their effects or increasing the risk of adverse reactions.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It can interact with monoamine oxidase inhibitors (MAOIs), increasing the risk of serious side effects such as high fever, severe headache, stiff muscles, and confusion. It can also interact with other central nervous system depressants, including alcohol, barbiturates, benzodiazepines, and narcotics, potentially leading to increased sedation and respiratory depression.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. It can interact with blood thinners, such as warfarin, increasing the risk of bleeding. It can also interact with other NSAIDs, corticosteroids, and alcohol, increasing the risk of gastrointestinal bleeding. Additionally, it can interact with angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), and diuretics, potentially reducing their effectiveness and increasing the risk of kidney damage.

Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body. It can interact with other local anesthetics and with class I antiarrhythmic drugs, such as tocainide and mexiletine, potentially leading to additive systemic toxicity. It can also interact with anti-epileptic drugs, such as phenytoin and phenobarbital, and with cimetidine, potentially altering the clearance of lidocaine and increasing the risk of side effects.

This formulation is used topically, which generally reduces the risk of systemic drug interactions. However, systemic absorption can still occur, especially when the formulation is applied over large areas of the body, on broken or inflamed skin, or under occlusive dressings. Therefore, it is important to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter drugs, and herbal supplements.

This formulation is used to treat various disease states. Cyclobenzaprine HCl can help to relieve muscle spasms associated with acute musculoskeletal conditions. Ketoprofen can help to reduce pain and inflammation associated with arthritis, bursitis, and tendonitis. Lidocaine HCl can help to relieve pain and itching caused by minor burns, sunburn, insect bites, and minor skin irritations. The combination of these ingredients in a single formulation allows for targeted treatment and absorption, potentially improving the effectiveness and convenience of therapy.

If you have any questions about this formulation or its potential drug interactions, please do not hesitate to reach out to us. We are here to help you understand your medications and use them safely and effectively.

How Does it Work

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This formulation combines three active ingredients: Cyclobenzaprine HCl, Ketoprofen, and Lidocaine HCl, each with a unique mechanism of action to provide relief from pain and inflammation. The formulation is designed to be applied topically, directly to the skin, where it can be absorbed to target the affected area.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is particularly effective in treating muscle spasms and associated pain. When applied topically, it can provide targeted relief to the affected area.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is used to treat mild to moderate pain, or inflammation caused by conditions such as arthritis. In this formulation, it is applied topically to provide direct relief to the area in need.

Lidocaine HCl is a local anesthetic that works by causing temporary numbness in the area where it is applied. It works by blocking nerve signals in your body and is often used to relieve pain and discomfort caused by skin irritations, sore throats, sunburn, teething pain, vaginal or rectal irritation, ingrown toenails, hemorrhoids, and many other sources of minor pain on the body surface.

The semisolid formulation dispensed through a pump mechanism allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin, providing targeted treatment to the affected area. This formulation is designed to provide relief from pain and inflammation, making it a versatile treatment option for a variety of conditions.

As compounding pharmacists, we have the knowledge and expertise to answer any questions you may have about this formulation. Whether you're a patient seeking relief from pain and inflammation, or a prescriber looking for an effective treatment option for your patients, we're here to help. Please don't hesitate to reach out to us with any questions.

Other Uses

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This formulation, containing Cyclobenzaprine HCl 2%, Ketoprofen 10%, and Lidocaine HCl 10%, is primarily designed as a topical gel to provide comforting relief from aches, pains, and strains. However, it may also be utilized for various other conditions, showcasing its diverse therapeutic potential.

With the inclusion of Lidocaine, an effective local anesthetic, it can also be utilized to numb the skin prior to a variety of minor medical procedures, thereby alleviating potential discomfort. The Cyclobenzaprine component, a muscle relaxant, may also make this formulation a suitable option for the treatment of muscle spasms and related conditions. Additionally, the anti-inflammatory properties of Ketoprofen would make this formulation potentially beneficial for patients with various inflammatory conditions, such as arthritis.

Patients should note that the gel's composition is non-irritating and typically well tolerated. However, it's essential to apply it as directed by the prescriber, usually thinly and only to the areas in need, and avoid putting it on open wounds or near sensitive areas like the eyes or mouth. Also, although it doesn't require a prescription, it should be used under the guidance of a healthcare professional, particularly for those with certain medical conditions or who are pregnant or breastfeeding.

Prescribers may explore the versatile usage of this formulation with their patients and clarify their unique requirements. They might find it beneficial for post-surgical pain management or an adjunct to physical therapy protocols in addition to its common uses. Importantly, they need to be aware of the patient's medical history, particularly in cases of liver disease, kidney disease, allergies, asthma, and bleeding disorders, before recommending this formulation, due to the contained active ingredients. Always start with the lowest effective dose and adjust based on the patient's response.

If you have any further inquiries concerning the diverse uses of this formulation or any other medication queries, don't hesitate to contact us at Bayview Pharmacy. Our team of skilled compounding pharmacists is always here to assist with your medical needs and support your health journey.

Frequently Asked Questions

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What is Cyclobenzaprine HCl 2%/Ketoprofen 10%/Lidocaine HCl 10% Topical Gel?

This is a compounded formulation designed for targeted application on the skin. It contains active ingredients in a gel-like consistency which are Cyclobenzaprine HCl 2%, Ketoprofen 10%, and Lidocaine HCl 10%.

How is this formulation dispensed?

The formulation is dispensed through a pump mechanism, allowing for easy and accurate application on targeted areas of the skin.

What is the use of this compounded formulation?

This topical gel is generally prescribed for the relief of local pain, inflammation, and muscle spasms, and to numb certain areas of the body.

How should I store this medication?

Store this medication in a cool, dry place away from light and moisture. It should not be stored in the bathroom. Keep all medicines away from children and pets.

What should I do if I miss a dose?

If you have been prescribed to use it regularly and you miss a dose, use it as soon as you remember. If it is near the time of your next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

What are the side effects of this topical gel?

Common side effects include redness, itching, or a mild stinging sensation at the application site. If these effects persist or worsen, contact your doctor immediately. Serious side effects are rare.

What precautions should I take before starting to use this formulation?

Inform your doctor if you are allergic to any of its active ingredients; or if you have any other allergies. Also, tell your doctor about your medical history, especially if you have any skin disorders or broken skin at the application site.

Can I use this topical gel during pregnancy or while breastfeeding?

If you are pregnant, plan to get pregnant, or are breastfeeding, consult with your doctor before using this medication. The active ingredients in the formulation may have potential risks that your doctor will need to assess.

What should I avoid while using this medication?

Avoid contact with the eyes, mouth, nose, and other sensitive areas. If contact occurs, wash the area thoroughly with water. Also, avoid heat, bandages, or plastic wrap on the applied area unless directed by your doctor.

Can I use other medications while using this topical gel?

Before starting this medication, make sure to inform your doctor about all prescription, non-prescription, over-the-counter medications, and herbal supplements you are using. Interactions with other drugs may alter the way this medication works and increase the risk of severe side effects.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.