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Cyclobenzaprine HCl 2%/Gabapentin 5%/Ketoprofen 20% Topical Gel

This formulation is a combination of Cyclobenzaprine HCl 2%, Gabapentin 5%, and Ketoprofen 20% in a topical gel form. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The Cyclobenzaprine HCl acts as a muscle relaxant, Gabapentin is used for nerve pain relief, and Ketoprofen serves as a potent anti-inflammatory agent. This unique combination is specifically designed to treat a variety of disease states including muscle spasms, neuropathic pain, and inflammation. The topical application allows for direct treatment of the affected area, reducing systemic side effects often associated with oral medications.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Cyclobenzaprine HCl 2%, Gabapentin 5%, and Ketoprofen 20%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency of the formulation ensures that the active ingredients are absorbed directly into the targeted area, providing localized relief.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain conditions. It works by stabilizing electrical activity in the brain and also affects the way the body senses pain. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body.

This unique combination of ingredients in the formulation works synergistically to provide relief from various disease states. It is particularly effective in treating conditions such as neuropathic pain, fibromyalgia, and musculoskeletal pain. The topical application allows for targeted treatment, reducing systemic side effects often associated with oral medications. It can also be beneficial for patients who have difficulty swallowing pills or for those who prefer not to take medication orally.

As with any medication, it is important to use this formulation as directed by your healthcare provider. Potential side effects may include skin irritation at the application site. If you experience any unusual symptoms, contact your healthcare provider immediately. It is also important to inform your healthcare provider of any other medications you are currently taking, as there may be potential interactions.

At Bayview Pharmacy, we are a team of knowledgeable compounding pharmacists dedicated to providing personalized medication solutions to meet the unique needs of each patient. If you have any questions about this formulation or how it may benefit you, please do not hesitate to reach out to us. We are here to help.

Drug Interactions

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This formulation combines three active ingredients: Cyclobenzaprine HCl, Gabapentin, and Ketoprofen. Each of these medications can interact with other drugs, potentially altering their effects or increasing the risk of adverse reactions. Therefore, it's crucial to inform your healthcare provider about all the medications you're currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements.

Cyclobenzaprine HCl, a muscle relaxant, can interact with monoamine oxidase inhibitors (MAOIs), increasing the risk of serious side effects such as high fever, severe headache, and increased heart rate. It can also interact with other central nervous system depressants like alcohol, barbiturates, benzodiazepines, and narcotics, potentially leading to increased sedation and respiratory depression.

Gabapentin, an anticonvulsant and nerve pain medication, can interact with antacids containing magnesium or aluminum, potentially reducing the absorption of Gabapentin. It's recommended to take Gabapentin at least two hours after taking an antacid. Gabapentin can also increase the effects of drugs that cause sedation, including opioids, antihistamines, and alcohol.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), can interact with blood thinners, increasing the risk of bleeding. It can also interact with other NSAIDs, corticosteroids, and alcohol, increasing the risk of gastrointestinal bleeding. Additionally, Ketoprofen can reduce the effectiveness of certain blood pressure medications and may interact with lithium, leading to increased lithium levels in the blood.

This formulation is designed to treat a variety of disease states. Cyclobenzaprine HCl is used to relieve muscle spasms associated with painful musculoskeletal conditions. Gabapentin is used to manage nerve pain associated with conditions such as shingles and diabetic neuropathy. Ketoprofen is used to reduce pain, swelling, and inflammation associated with conditions like arthritis. By combining these three medications into a single topical gel, this formulation provides targeted treatment for pain and inflammation directly at the site of the problem, potentially reducing systemic side effects.

If you have any questions about this formulation or its potential interactions with other medications, please don't hesitate to reach out to us. We're here to help ensure that your treatment is safe and effective.

How Does it Work

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The Cyclobenzaprine HCl 2%/Gabapentin 5%/Ketoprofen 20% Topical Gel is a unique formulation that combines three active ingredients, each with its own mechanism of action, to provide targeted relief from pain and inflammation. This semisolid formulation is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is particularly effective in treating muscle spasms and associated pain. When applied topically, Cyclobenzaprine HCl can provide targeted relief from muscle spasms without the systemic side effects associated with oral administration.

Gabapentin is a medication that is primarily used to treat seizures and nerve pain. It works by affecting the chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. In this topical formulation, Gabapentin can provide direct relief from nerve pain at the site of application.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. When applied topically, Ketoprofen can provide targeted relief from pain and inflammation without the gastrointestinal side effects associated with oral NSAIDs.

Together, these three active ingredients work synergistically to provide targeted relief from pain and inflammation. The topical application allows for the active ingredients to be absorbed directly into the affected area, providing faster and more effective relief compared to oral medications. Furthermore, the pump mechanism allows for easy and precise dosing, ensuring that the patient receives the optimal amount of medication for their condition.

If you have any questions about this formulation, please do not hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.

Other Uses

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In addition to its prescribed use for treating pain, the semisolid formulation of Cyclobenzaprine HCl 2%/Gabapentin 5%/Ketoprofen 20% Topical Gel has been utilized in several 'off-label' applications. Although it's essential to note the necessity for professional medical advice, this formulation is found to be beneficial in diminishing neuropathic pain associated with shingles or herpes zoster, particularly postherpetic neuralgia. Given the analgesic and anti-inflammatory effects of the active ingredients, it may also grant relief for tendinitis and bursitis.

Athletes and other physically active individuals suffering from muscle sprains, strains, or other musculoskeletal injuries may also find this topical formulation beneficial in alleviating their painful symptoms and reducing inflammation. Gabapentin, in particular, can inhibit various neurotransmitters in the nervous system, helping to alleviate nerve pain from injuries.

Individuals suffering from chronic pain conditions such as fibromyalgia have also reportedly found relief using this formulation. The ability of Cyclobenzaprine to act as a muscle relaxant can contribute substantially to this effect, lowering muscle tension, and hence, reducing the overall experience of pain.

Lastly, certain chronic, inflammatory skin conditions - such as psoriasis or eczema - may also witness lessening in symptoms if treated with this formulation. The potent anti-inflammatory action of Ketoprofen can reduce the associated inflammation, and thus, potentially decrease the severity of symptoms.

Despite these potential other uses, it is crucial to mention that this topical gel should always be used under the supervision of a healthcare provider. Unsupervised use may lead to adverse reactions or ineffective treatment. For further inquiries about the Cyclobenzaprine HCl 2%/Gabapentin 5%/Ketoprofen 20% Topical Gel or its potential uses, do not hesitate to reach out to us at Bayview Pharmacy. We’re here to provide personalized, effective, and safe pharmacological solutions for your needs.

Frequently Asked Questions

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What is Cyclobenzaprine HCl 2%/Gabapentin 5%/Ketoprofen 20% Topical Gel?

This is a compounded formulation of three active ingredients: Cyclobenzaprine HCl, Gabapentin, and Ketoprofen. It's a semisolid formulation that is easily dispensed through a pump mechanism for targeted treatment on the skin.

What is the purpose of this formulation?

This topical gel has been designed to deliver relief from pain or discomfort. The different active ingredients work together to provide an effective pain management solution.

How should I apply this gel?

You should apply the gel to the affected area as directed by your doctor. The pump mechanism facilitates easy and precise application to the skin.

Does the gel have any specific storage requirements?

You should store this medication at room temperature, away from heat and direct light. Do not freeze and keep out of reach from children and pets.

What are the potential side effects of this medication?

The side effects of this formulation can vary based on the individual but can include skin irritation or redness at the application site. If you experience any severe reactions, contact your doctor immediately.

How does the gel consistency contribute to its function?

The gel-like consistency allows for a smooth application on the skin and enables the active ingredients to be readily absorbed, thus increasing their efficacy.

Can I apply the topical gel more than once a day?

You should follow your healthcare provider's instructions regarding the frequency of application. Overuse can increase the risk of side effects.

Should I use more gel to treat severe pain?

No, using more gel does not necessarily mean more pain relief. Always use the recommended amount and consult your healthcare provider if your symptoms do not improve.

Can I apply this gel to broken or irritated skin?

Generally, this gel should not be applied to wounds or irritated skin. Consult your healthcare provider for specific instructions regarding your case.

What happens if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and return to your regular dosing schedule.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.