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Cyclobenzaprine HCl 2%/Gabapentin 5%/Ketoprofen 20% Topical Gel

This formulation is a combination of Cyclobenzaprine HCl 2%, Gabapentin 5%, and Ketoprofen 20% in a topical gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The Cyclobenzaprine HCl component is a muscle relaxant that works by blocking nerve impulses to the brain. Gabapentin is an anticonvulsant and nerve pain medication that is used to treat nerve pain caused by shingles (postherpetic neuralgia). Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body.

This formulation is used to treat various disease states including muscle spasms, nerve pain, and inflammation. It provides targeted relief by delivering the active ingredients directly to the affected area, reducing systemic side effects.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Cyclobenzaprine HCl 2%, Gabapentin 5%, and Ketoprofen 20%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency of the formulation ensures that the active ingredients are absorbed effectively into the targeted area.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain conditions. It works by calming down nerve activity, thereby reducing pain sensation. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body.

Together, these three active ingredients work synergistically to provide relief from various disease states. The high concentration of Ketoprofen provides potent anti-inflammatory and analgesic effects, making it effective for conditions such as arthritis, bursitis, and other inflammatory diseases. Gabapentin, on the other hand, is effective in managing neuropathic pain, which is often associated with conditions such as postherpetic neuralgia and diabetic neuropathy. Cyclobenzaprine HCl enhances the formulation's effectiveness by providing muscle relaxation, which can be beneficial in conditions involving muscle spasms or tension.

It's important to note that this formulation is intended for topical use only and should not be ingested or applied to open wounds or damaged skin. As with any medication, it's crucial to use this formulation as directed by a healthcare provider. Side effects may include skin irritation at the application site, dizziness, or drowsiness. If these side effects persist or worsen, or if you experience any serious side effects such as mood changes or swelling of the hands or feet, seek medical attention immediately.

As compounding pharmacists, we are committed to providing high-quality, personalized medications to meet the unique needs of our patients. If you have any questions about this formulation or how it may benefit you, please don't hesitate to reach out to us at Bayview Pharmacy. We are here to help.

Drug Interactions

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This formulation contains three active ingredients: Cyclobenzaprine HCl, Gabapentin, and Ketoprofen. Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain and seizures. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body.

When used together in a topical gel, these three medications can provide targeted relief for a variety of conditions. The Cyclobenzaprine HCl can help to relax muscles and reduce spasms, the Gabapentin can help to reduce nerve pain, and the Ketoprofen can help to reduce inflammation and pain. This makes the formulation particularly useful for conditions such as neuropathic pain, musculoskeletal pain, and inflammation.

However, it's important to be aware of potential drug interactions. Cyclobenzaprine HCl can interact with other medications that cause drowsiness, including alcohol, antihistamines, drugs for sleep or anxiety, other muscle relaxants, and narcotic pain relievers. It can also interact with certain antidepressants. Gabapentin can interact with antacids containing aluminum or magnesium, as they can decrease the absorption of Gabapentin. Ketoprofen can interact with aspirin, blood thinners, corticosteroids, and other NSAIDs, as well as certain medications for high blood pressure.

It's also important to note that while this formulation is designed for topical use, some of the medication may be absorbed into the bloodstream, which could potentially lead to systemic side effects or interactions. Therefore, it's important to inform your healthcare provider of all medications you are currently taking, including over-the-counter drugs and supplements, before starting this treatment.

As with any medication, it's important to use this formulation as directed by your healthcare provider. If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. We're here to help ensure that your treatment is safe and effective.

How Does it Work

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The Cyclobenzaprine HCl 2%/Gabapentin 5%/Ketoprofen 20% Topical Gel is a unique formulation that combines three active ingredients, each with its own mechanism of action, to provide targeted relief from various disease states. This semisolid formulation is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is particularly effective in treating muscle spasms and associated pain. When applied topically, Cyclobenzaprine HCl can provide targeted relief by acting directly on the affected muscles.

Gabapentin is an anticonvulsant and nerve pain medication. It is often used to treat nerve pain conditions such as postherpetic neuralgia and peripheral neuropathy. Gabapentin works by stabilizing electrical activity in the nervous system and decreasing the release of neurotransmitters that transmit pain signals. In a topical formulation, Gabapentin can provide direct relief to the area of pain, reducing the need for systemic medication and associated side effects.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is commonly used to relieve pain, swelling, and joint stiffness caused by arthritis. When applied topically, Ketoprofen can provide targeted anti-inflammatory and analgesic effects, reducing pain and inflammation in the specific area of application.

Together, these three active ingredients work synergistically to provide comprehensive pain relief. The topical application allows for targeted treatment, reducing the need for systemic medication and associated side effects. It is important to use this medication as directed by your healthcare provider, and to not use more than the recommended dose. If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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The Cyclobenzaprine HCl 2%/Gabapentin 5%/Ketoprofen 20% Topical Gel is primarily designed for effective relief from pain and inflammation in targeted areas. Each ingredient plays a fundamental role in delivering the desired therapeutic effects. Cyclobenzaprine HCl functions as a muscle relaxant, easing strains, spasms, or other muscle injuries. Gabapentin, meanwhile, is an anticonvulsant traditionally used to alleviate neuropathic pain. Ketoprofen is an NSAID, which helps to reduce pain and inflammation. While the formulation is primarily used for managing pain and inflammation, it may also have other applications.

This formulation may be used in treating symptoms associated with conditions such as fibromyalgia, where muscle pain and tightness are prevalent. Its muscle-relaxing and analgesic properties can provide much-needed relief. It may also be effective in treating strains, sprains, and similar minor injuries, helping the healing process by reducing inflammation and pain.

Another potential application lies in managing the discomfort from chronic conditions such as osteoarthritis or rheumatoid arthritis. Particularly when these conditions impact smaller, easily accessible joints (like those in the hands), direct cutaneous application can target the site of pain and inflammation. Additionally, its topical nature allows for localized treatment with potentially fewer systemic side effects than oral medication.

It is also worth noting that while this formulation primarily targets pain and inflammation, the inclusion of Gabapentin implies potential use in managing neuropathic conditions, for example, diabetic neuropathy or postherpetic neuralgia, where there is nerve damage pain.

However, this formulation should only be used as prescribed by a healthcare professional, and it is essential to inform your healthcare provider of all your medical history and current medications. Overusing or incorrectly using this formulation can result in severe, undesirable effects. Always follow the instructions closely, apply the gel only to the recommended areas, avoid contact with eyes, and wash your hands thoroughly after each application. Any side effects or adverse reactions should be reported immediately to the healthcare provider.

If you have any questions or concerns about this formulation or its uses, do not hesitate to reach out to us at Bayview Pharmacy. Our team of expert compounding pharmacists is ready to provide you with detailed, personalized information. We are committed to your health and well-being.

Frequently Asked Questions

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What is the purpose of this compounded formulation of Cyclobenzaprine HCl 2%/Gabapentin 5%/Ketoprofen 20% Topical Gel?

This compounded topical gel contains three active ingredients: Cyclobenzaprine HCl, Gabapentin, and Ketoprofen, which work together to relieve pain and inflammation. It's beneficial for targeted treatment due to its easy application on the skin.

How does the pump mechanism of this product work?

The pump mechanism simplifies the application process. By pressing the pump, a specific amount of the gel is dispensed, contributing to a more precise dosage and less waste. This helps ensure that you are using the correct dose.

What does 'semisolid formulation' mean?

A semisolid formulation refers to the consistency of the product. This cyclobenzaprine/gabapentin/ketoprofen gel is not as solid as a cream nor as liquid as a lotion, but sits somewhere in between. It's easy to apply without being messy.

Can this compounded gel be applied anywhere on the body?

This formulation is designed for topical use and should be applied directly to the area where pain and inflammation are present. However, it should not be used on broken skin, wounds, or mucous membranes. Always follow your healthcare provider's instructions.

Is it possible to use too much of this gel?

Yes, like any medication, it's essential to use this product as prescribed by your healthcare provider. Using more than the recommended dose increases the risk of side effects.

Does the gel get absorbed through the skin?

Yes, the active ingredients of the gel are absorbed through the skin to provide local relief of pain and inflammation. However, the level of absorption can vary depending on several factors including the skin's thickness and the area of application.

Does the gel have a particular smell or color?

Topical gels usually have little to no scent or color, but some ingredients may give the formulation a specific scent or hue. If you have any concerns, consult with your healthcare provider or pharmacist.

Does this formulation have any side effects?

Potential side effects can include skin irritation, redness, and itching in the area of application. If these side effects persist or worsen, contact your healthcare provider promptly.

What should I do if I miss a dose?

If you miss a dose, simply apply the gel as soon as you remember. However, if it's close to the time for your next dose, skip the missed one and return to your regular schedule. Do not use extra gel to make up for the missed dose.

Where should this gel be stored?

The gel should be stored at room temperature, out of reach and sight of children. It should not be exposed to high heat or freezing as this can degrade the product. Always check the packaging for specific storage instructions.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.