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Cyclobenzaprine HCl 2%/Gabapentin 4%/Ketoprofen 10%/Lidocaine HCl 5% Transdermal Gel

This formulation is a combination of Cyclobenzaprine HCl 2%, Gabapentin 4%, Ketoprofen 10%, and Lidocaine HCl 5% in a transdermal gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The formulation is designed to treat a variety of disease states. Cyclobenzaprine HCl is a muscle relaxant used to relieve muscle spasms, Gabapentin is an anticonvulsant and nerve pain reliever used to treat seizures and pain caused by shingles, Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, swelling, and joint stiffness caused by arthritis, and Lidocaine HCl is a local anesthetic used to numb the skin and decrease pain and discomfort.

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Cyclobenzaprine Hydrochloride
Gabapentin
Ketoprofen
Lidocaine Hydrochloride
Topical Gel
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Formula Information

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This formulation is a compounded transdermal gel containing Cyclobenzaprine HCl 2%, Gabapentin 4%, Ketoprofen 10%, and Lidocaine HCl 5%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency of the formulation ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain caused by shingles (herpes zoster) or other nerve pain conditions. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body. Together, these ingredients work synergistically to provide relief from various disease states.

This formulation is particularly effective in treating conditions such as neuropathic pain, fibromyalgia, post-herpetic neuralgia, and musculoskeletal pain. The combination of a muscle relaxant, an anticonvulsant, an anti-inflammatory, and a local anesthetic provides a comprehensive approach to pain management, addressing not only the symptoms but also the underlying causes of pain. The transdermal delivery method ensures that the active ingredients are delivered directly to the affected area, providing targeted relief while minimizing systemic side effects.

It is important to note that this formulation should be used as directed by a healthcare provider. Patients should apply the gel to the affected area as directed, and should not use more than the recommended dose. Side effects may include skin irritation at the application site, dizziness, drowsiness, or dry mouth. If these side effects persist or worsen, or if you experience serious side effects such as mood changes, trouble sleeping, or severe stomach pain, contact your healthcare provider immediately.

If you have any questions about this formulation, or if you would like more information about how it can be used to treat specific conditions, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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This formulation combines four active ingredients: Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl. Each of these ingredients has its own potential for drug interactions, which can be amplified when used in combination. Therefore, it's crucial to consider the potential interactions of each component when prescribing this medication.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It may interact with monoamine oxidase inhibitors (MAOIs), increasing the risk of serious side effects such as high body temperature, high blood pressure, muscle rigidity, and severe nervous system reactions. It may also interact with other medications that cause drowsiness such as benzodiazepines, sleeping pills, and narcotic pain relievers, potentially leading to increased sedation and respiratory depression.

Gabapentin is an anticonvulsant and nerve pain medication. It may interact with antacids containing aluminum or magnesium, as they can decrease the absorption of gabapentin and reduce its effectiveness. Gabapentin may also increase the effects of other drugs that cause drowsiness, including antihistamines, opioids, and sedatives.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, swelling, and inflammation. It may interact with blood thinners, increasing the risk of bleeding. It may also interact with other NSAIDs, corticosteroids, and alcohol, increasing the risk of stomach and intestinal bleeding. Additionally, ketoprofen may decrease the effectiveness of certain high blood pressure medications and diuretics.

Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. While lidocaine is generally considered safe and has minimal systemic absorption, it may interact with other local anesthetics and medications used to treat irregular heart rhythms.

This formulation is designed to treat a variety of disease states. The combination of a muscle relaxant (Cyclobenzaprine HCl), a nerve pain medication (Gabapentin), an anti-inflammatory (Ketoprofen), and a local anesthetic (Lidocaine HCl) makes it particularly effective for conditions involving muscle pain, nerve pain, inflammation, and localized pain. These may include conditions such as fibromyalgia, neuropathic pain, arthritis, and other musculoskeletal conditions.

As always, it's important for patients and prescribers to discuss all medications, supplements, and over-the-counter products currently being used to avoid potential interactions. If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy.

How Does it Work

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This formulation is a combination of four active ingredients: Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl, each playing a unique role in managing pain and inflammation. The formulation is designed to be applied topically, directly to the skin, where it is absorbed and begins to work.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is particularly effective in treating muscle spasms and provides relief by relaxing the muscles in the body. Gabapentin, on the other hand, is an anticonvulsant and nerve pain medication. It is believed to work by affecting the way the body senses pain. It is often used to treat nerve pain conditions, such as postherpetic neuralgia, and can also help reduce the intensity of pain signals reaching the brain.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is commonly used to relieve pain, swelling, and joint stiffness caused by arthritis. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It works by blocking nerve signals in your body and is used to reduce pain or discomfort caused by skin irritations such as sunburn, insect bites, poison ivy, poison oak, poison sumac, and minor cuts, scratches, or burns.

The transdermal gel formulation allows for the active ingredients to be absorbed through the skin directly into the bloodstream. This method of delivery bypasses the digestive system, reducing the risk of systemic side effects and providing targeted relief to the area where the medication is applied. The pump mechanism allows for easy and precise application of the medication.

This formulation is particularly useful in treating conditions such as neuropathic pain, arthritis, muscle spasms, and localized pain conditions. By combining these four active ingredients, it provides a multi-pronged approach to pain management, addressing pain signals at different stages and through different mechanisms. This can provide more comprehensive pain relief than a single medication alone.

If you have any questions about this formulation, how it works, or how it may be beneficial in treating your specific condition, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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This specific formulation of Cyclobenzaprine HCl 2%/Gabapentin 4%/Ketoprofen 10%/Lidocaine HCl 5% Transdermal Gel offers a unique combination of active ingredients known to provide relief from pain and muscle stiffness, primarily used for localized neuropathic pain. However, with the range of active ingredients within the preparation, it may potentially be beneficial for other uses as well. Some of these could include other types of chronic pain conditions, muscle spasms, herniated disc pain, and post-herpetic neuralgia, which may benefit from the muscle relaxant and analgesic properties this formulation provides.

While typically applied in a localized region for targeted relief, the properties of gabapentin and cyclobenzaprine have the potential to address neuropathic pain or nerve-based discomforts owing to their neurological effects. Additionally, with Ketoprofen's anti-inflammatory properties, this formulation might be beneficial for conditions with inflammation components such as arthritis, bursitis or tendonitis. Lidocaine HCl provides additional analgesic comfort, making this formulation a useful choice for non-invasive, topical treatment of various painful conditions.

Nevertheless, it is essential to note that usage of this formulation for conditions other than what it is primarily intended for should be done under a physician's guidance and supervision. This formulation, like any medication, might interact with other medications or pre-existing health conditions, or may be contraindicated in certain situations. Therefore, before any new use is made of this formulation, consultation with a healthcare provider is strongly recommended.

Additionally, while the transdermal gel preparation is designed to provide easy and precise application, care should be taken not to apply to broken or irritated skin or to use this medication in any way other than as directed by a medical professional as prolonged use or excessive dosage might increase the risk of side effects.

If you have any questions about this medication, its potential uses, or any other aspects of its administration, our team at Bayview Pharmacy is always available. Please feel free to reach out to us; we are committed to ensuring that you have all the information you need to use our medications safely and effectively.

Frequently Asked Questions

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What is this formulation used for?

Cyclobenzaprine HCl 2%/Gabapentin 4%/Ketoprofen 10%/Lidocaine HCl 5% Transdermal Gel is usually used for the relief of severe and chronic pain. The components have analgesic, muscle relaxant, and anti-inflammatory properties which can help provide targeted pain relief.

How should I apply this medication?

This is a transdermal gel, meaning it is applied directly to the skin. Take the quantity as directed by your doctor and apply it to the affected area. It is dispensed through a pump mechanism, so you can easily control your dosage.

Who should not use this medication?

People with allergies to any of the ingredients, pregnant women, or people with specific medical conditions may not be suitable for this treatment. Always consult with your healthcare provider about any concerns before starting or stopping any medication.

Are there any side effects?

Possible side effects can vary depending upon the individual and the length of use. Side effects may include skin reactions, dizziness, upset stomach, or more severe reactions in case of allergies. If you have any unusual or severe side effects, please call your healthcare provider immediately.

Can I use it for any type of pain?

While this formulation is potent and can help with various types of severe or chronic pain, it should only be used as directed by a qualified healthcare provider. It is important that it is applied to the targeted area for which it is prescribed.

What does the transdermal delivery mechanism do?

A transdermal delivery allows for the active ingredients in the gel to be absorbed through the skin, directly into the bloodstream. This offers an advantage over oral medications, providing faster relief and targeting the specific area where the medication is needed.

Does the pump dispenser offer any advantages?

Yes, the pump dispenser is advantageous as it allows for precise and controlled dispensement of the gel. This decreases risk of overdose and enhances convenience by eliminating the need for measurement.

Can I use this medication while taking other prescribed medications?

Always consult your healthcare provider before starting any new medication, especially if you are already taking other medications. The ingredients in this compound may interact with other substances, potentially causing adverse effects.

How long does it take for the gel to work?

The duration before the onset of pain relief can vary depending upon the severity of the pain as well as individual absorption rates. In general, relief may be observed shortly after application.

Can I apply more if the pain doesn’t lessen?

Always use the medication as instructed by your doctor. If you find that the prescribed dosage isn't relieving your pain, consult your doctor for advice instead of increasing the dosage on your own.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.