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Cyclobenzaprine HCl 1%/Ketoprofen 10%/Lidocaine HCl 5.8% Transdermal Gel

This formulation is a combination of Cyclobenzaprine HCl 1%, Ketoprofen 10%, and Lidocaine HCl 5.8% in a transdermal gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The formulation is used to treat various disease states. Cyclobenzaprine HCl is a muscle relaxant that helps to relieve muscle spasms caused by certain conditions such as sprains, strains, or other muscle injuries. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, swelling, and inflammation. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This combination is often used to manage conditions like arthritis, bursitis, acute injuries, or other forms of pain and inflammation.

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Topical Gel
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Formula Information

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This formulation is a unique combination of Cyclobenzaprine HCl 1%, Ketoprofen 10%, and Lidocaine HCl 5.8% in a transdermal gel. Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This combination of ingredients is designed to provide targeted relief from pain and inflammation.

The transdermal gel is a semisolid formulation that is dispensed through a pump mechanism. This allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for targeted treatment. This formulation is particularly beneficial for patients who have difficulty swallowing pills or those who prefer a topical treatment option.

This formulation can be used to treat a variety of disease states. The muscle relaxant properties of Cyclobenzaprine HCl make it useful in treating muscle spasms and stiffness associated with conditions like fibromyalgia or other musculoskeletal conditions. Ketoprofen, with its anti-inflammatory properties, can help manage pain and inflammation associated with conditions such as arthritis, gout, or injury. Lidocaine HCl provides temporary relief from pain associated with minor skin irritations, burns, and abrasions, as well as providing local anesthesia for minor surgical procedures.

As with any medication, it's important to use this formulation as directed by your healthcare provider. Side effects can include skin irritation at the application site, dizziness, or drowsiness. If you experience any severe side effects or allergic reactions, seek medical attention immediately. Always inform your healthcare provider of any other medications you are taking to avoid potential drug interactions.

If you have any questions about this formulation, its uses, or how to properly apply it, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you with any concerns or inquiries you may have.

Drug Interactions

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This formulation combines three active ingredients: Cyclobenzaprine HCl, Ketoprofen, and Lidocaine HCl. Each of these ingredients has its own potential for drug interactions, which can be amplified when used in combination. Therefore, it's crucial to consider the potential interactions of each component when prescribing or using this medication.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It may interact with monoamine oxidase inhibitors (MAOIs), increasing the risk of serious side effects such as high fever, severe headache, stiffness, confusion, and increased heart rate. It may also interact with other medications that cause drowsiness such as antihistamines, opioids, sleeping pills, and alcohol, leading to increased sedation and potential respiratory depression.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. It may interact with blood thinners, other NSAIDs, and corticosteroids, increasing the risk of gastrointestinal bleeding. It may also interact with ACE inhibitors, angiotensin II receptor blockers (ARBs), or diuretics, potentially reducing their effectiveness and increasing the risk of kidney damage.

Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body. It may interact with other local anesthetics and medications used to treat irregular heart rhythms, potentially leading to serious side effects such as slow or irregular heartbeat, dizziness, fainting, and seizures.

This formulation is designed for transdermal application, which means it's applied directly to the skin. This can reduce some systemic drug interactions, but it doesn't eliminate them entirely. It's also important to note that this formulation can interact with other topically applied medications, potentially increasing the absorption and effects of either medication.

This formulation is used to treat conditions such as muscle pain, inflammation, and localized nerve pain. The combination of a muscle relaxant, an anti-inflammatory, and a local anesthetic allows for targeted treatment of these conditions, reducing pain and inflammation while also relaxing tense muscles.

As always, it's important to discuss all medications, supplements, and health conditions with your healthcare provider before starting a new medication. If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. We're here to help.

How Does it Work

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The Cyclobenzaprine HCl 1%/Ketoprofen 10%/Lidocaine HCl 5.8% Transdermal Gel is a unique formulation that combines the therapeutic benefits of three active ingredients. This semisolid formulation is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed directly into the targeted area, providing localized treatment.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is particularly effective in treating muscle spasms and associated pain. When applied topically in a gel form, Cyclobenzaprine HCl can directly target the affected muscles, providing relief without the systemic side effects often associated with oral administration.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is commonly used to relieve pain, swelling, and joint stiffness caused by arthritis. In this transdermal gel formulation, Ketoprofen can be applied directly to the site of pain or inflammation, providing targeted relief.

Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It is often used to relieve skin irritations, minor burns, and to treat discomfort associated with certain medical procedures. In this formulation, Lidocaine HCl enhances the pain-relieving effects of Cyclobenzaprine HCl and Ketoprofen, providing immediate relief from pain and discomfort.

Together, these three active ingredients work synergistically to provide effective relief from muscle spasms, pain, and inflammation. The transdermal gel formulation allows for targeted treatment, reducing the risk of systemic side effects and improving patient compliance. It is important to use this medication as directed by your healthcare provider, and to not use more than the recommended dose.

If you have any questions about this formulation, or if you would like more information on how it can benefit your specific condition, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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This compounded formulation of Cyclobenzaprine Hydrochloride (HCl) 1%, Ketoprofen 10%, and Lidocaine HCl 5.8% in a transdermal gel is primarily used as a topical treatment to provide relief from pain, inflammation, and muscular or skeletal discomfort. However, this unique combination, can have other uses as well.

In addition to its primary usage, this formulation can be utilized in alleviating chronic pain associated with disorders or conditions such as fibromyalgia, numerous neuropathies, and arthritis due to its anti-inflammatory and analgesic properties. It has shown potential in managing post-operative pain and sports-related injuries as well.

Moreover, Lidocaine present in the formulation, a local anesthetic, provides numbing effects preventing the transmission of pain signals. It could potentially be used in minor clinical procedures requiring localized anesthesia.

The muscle relaxant Cyclobenzaprine HCl could be beneficial for those suffering from muscle spasms or discomfort associated with sprains, strains, or other musculoskeletal conditions. The Ketoprofen in the mixture lends its potent anti-inflammatory and analgesic properties that can help manage conditions characterized by inflammation and pain.

Finally, this transdermal gel formulation allows for targeted application and better skin penetration, offering consistent delivery of active pharmaceutical ingredients to the desired area. Please note that this medication should be used under a healthcare provider's direct supervision to ensure its safety and efficacy.

As with any compounded medication, potential off-label uses should be thoroughly discussed with a healthcare provider who can address individual patient needs and concerns. The topical nature of this medication reduces systemic exposure and hence, system-wide side effects; however, individual tolerance and reaction to the medication might vary substantially. For queries or further clarification regarding this formulation or its potential use cases, please feel free to reach out to us.

Frequently Asked Questions

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What is the use of this compounded formulation of Cyclobenzaprine HCl 1%/Ketoprofen 10%/Lidocaine HCl 5.8% Transdermal Gel?

This formulation is intended for targeted treatment or absorption of active ingredients through the skin. It combines the muscle relaxant effects of Cyclobenzaprine, the pain relief and anti-inflammatory properties of Ketoprofen, and the local anesthetic power of Lidocaine.

How should this product be applied?

This transdermal gel is dispensed through a pump mechanism and should be applied directly onto the skin. The amount of gel needed will depend on the directions provided by your healthcare provider. Ensure that you apply it evenly and massage it gently into your skin until it’s fully absorbed.

What kind of texture does this gel have?

This is a semisolid formulation with a gel-like consistency. It is not greasy or sticky and is designed to be easily absorbed through the skin.

Can everyone use this gel?

As with any medication, it should be used under the supervision of a healthcare provider. Certain individuals may need to avoid it, especially those with known allergies to any of the active ingredients or who have any specific skin conditions. Always consult your healthcare provider before starting any new medication.

Can I use this gel on any area of my body?

The gel should be applied on the specific area as directed by your healthcare provider. Do not apply the gel onto open wounds, in or around the eyes or mucous membranes.

What are the possible side effects of using this gel?

Individuals may react differently to any medication. Common side effects could include skin irritation at the application site. Serious side effects are rare, but may include allergic reactions. If you notice any unusual or severe reactions, contact your healthcare provider immediately.

Can this gel be used in conjunction with other medications?

Interactions can occur with certain medications. Therefore, you should always inform your healthcare provider about any other medications or supplements you are currently taking.

Is this gel safe for use during pregnancy or breastfeeding?

As with any medication, this should be discussed with your healthcare provider. They will be able to provide guidance based on your specific health circumstances and the current medical guidelines for use of these medications during pregnancy or breastfeeding.

How should the gel be stored?

Store this gel at room temperature away from direct sunlight. Also, keep it out of reach from children.

What should I do if I forgot a dose?

If you missed a dose, apply it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and move back to your regular dosing schedule. Do not double the dose to make up for the missed application.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.