This formulation is a combination of Cyclobenzaprine HCL 2%, Ibuprofen 10%, Ketoprofen 10%, Piroxicam 2% in a transdermal gel. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency of the formulation ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

Cyclobenzaprine HCL is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Ibuprofen and Ketoprofen are nonsteroidal anti-inflammatory drugs (NSAIDs) that reduce substances in the body that cause pain and inflammation. Piroxicam is also an NSAID and is used to relieve pain, swelling, and joint stiffness caused by arthritis. The combination of these medications in a transdermal gel allows for targeted relief at the site of pain or inflammation.

This formulation is particularly useful in treating various disease states that involve pain and inflammation. These include conditions such as arthritis, muscle sprains and strains, and other musculoskeletal conditions. The transdermal application allows for the active ingredients to be delivered directly to the affected area, providing localized relief while minimizing systemic side effects that can occur with oral administration of these medications.

It is important for patients and prescribers to understand that while this formulation can provide significant relief from pain and inflammation, it should be used as part of a comprehensive treatment plan that may include physical therapy, rest, and other medications. As with any medication, it is important to use this formulation as directed by a healthcare provider to ensure its safety and effectiveness.

If you have any questions about this formulation, its use, or any other aspect of your medication regimen, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you with any concerns or queries you may have.

This formulation contains a combination of active ingredients, including Cyclobenzaprine HCL, Ibuprofen, Ketoprofen, and Piroxicam, all of which are delivered transdermally via a gel. Each of these ingredients has its own potential for drug interactions, which can be amplified when used in combination.

Cyclobenzaprine HCL is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It may interact with drugs such as monoamine oxidase inhibitors (MAOIs), certain antidepressants, and alcohol, leading to potentially serious side effects such as serotonin syndrome. It is also advised to avoid using Cyclobenzaprine HCL with other medications that can cause drowsiness or slow your breathing, such as opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Ibuprofen and Ketoprofen are nonsteroidal anti-inflammatory drugs (NSAIDs) that reduce hormones that cause inflammation and pain in the body. They may interact with drugs such as aspirin, anticoagulants like warfarin, other NSAIDs, and certain types of antidepressants. These interactions can increase the risk of serious gastrointestinal (GI) side effects including inflammation, bleeding, ulceration, and perforation of the stomach or intestines. Additionally, using Ibuprofen and Ketoprofen with angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs) can reduce their effectiveness and potentially lead to kidney damage.

Piroxicam is also an NSAID and carries similar interaction risks as Ibuprofen and Ketoprofen. It may also interact with blood pressure medications, leading to an increased risk of kidney problems, and with methotrexate, increasing the risk of methotrexate toxicity.

Given the potential for these interactions, it is crucial to inform your healthcare provider of all medications, both prescription and over-the-counter, as well as any supplements you are currently taking. This will help to ensure safe and effective use of this medication. It is also important to note that while this formulation is designed for transdermal application, it should not be applied to broken or irritated skin, as this can increase absorption and potentially lead to systemic side effects.

This formulation is primarily used to treat localized pain and inflammation, such as that associated with arthritis, sprains, strains, and other musculoskeletal conditions. The combination of active ingredients works to reduce inflammation, alleviate pain, and relax muscles in the targeted area, providing relief without the systemic side effects often associated with oral medications.

If you have any questions about this formulation, its potential interactions, or its use in treating specific conditions, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide the information and support you need to make informed decisions about your health.

This unique formulation combines the muscle relaxant properties of Cyclobenzaprine HCL, the anti-inflammatory and analgesic effects of Ibuprofen and Ketoprofen, and the anti-inflammatory action of Piroxicam in a transdermal gel. The gel is designed to be applied topically to the skin, where it is absorbed into the underlying tissues to provide targeted relief from pain and inflammation.

Cyclobenzaprine HCL works by blocking nerve impulses (or pain sensations) that are sent to your brain, helping to reduce muscle spasms. Ibuprofen and Ketoprofen are nonsteroidal anti-inflammatory drugs (NSAIDs) that work by reducing hormones that cause inflammation and pain in the body. Piroxicam is also an NSAID, and it works by blocking the production of certain substances in the body that cause inflammation. This combination of active ingredients provides a multi-faceted approach to pain management, addressing both the symptoms and the underlying causes of pain and inflammation.

The transdermal gel formulation allows for the active ingredients to be absorbed directly into the affected area, providing targeted relief. This can be particularly beneficial for conditions such as arthritis, muscle strains, and other forms of musculoskeletal pain, where inflammation and pain are localized to specific areas of the body. The gel is dispensed through a pump mechanism, which allows for easy and precise application. This can help to ensure that the medication is applied exactly where it is needed, and in the correct amounts.

It's important to note that while this formulation can provide significant relief from pain and inflammation, it is not a cure for the underlying conditions causing these symptoms. It should be used as part of a comprehensive treatment plan, under the guidance of a healthcare provider. As with any medication, it's important to use this formulation as directed, and to communicate with your healthcare provider about any side effects or concerns that you may have.

If you have any questions about this formulation, or if you would like more information about how it can be used to manage your specific condition, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

This compounded transdermal formulation has primarily been used to treat a variety of pain-associated conditions and inflammation, especially musculoskeletal conditions such as arthritis, tendinitis, back pain, and sports injuries. Aside from these primary uses, this gel may also be useful for other off-label conditions based upon its individual active components.

For instance, Cyclobenzaprine, a muscle relaxer in this formulation, may benefit fibromyalgia patients by reducing pain and improving sleep and functional status. Ibuprofen and Ketoprofen, both well-known nonsteroidal anti-inflammatory drugs (NSAIDs), may subdue simple conditions like headaches, migraines or pains associated with menstrual cramps. Piroxicam's potent analgesic and anti-inflammatory properties might be beneficial in the targeted external treatment of gout.

Moreover, considering the transdermal absorption properties of the gel carrier, it can provide a targeted, sustained release of medications directly in the affected area, potentially benefiting patients with other localized pain conditions. It is also noteworthy that these alternatives uses warrant further clinical investigation and should always be considered under the guidance of a healthcare provider.

Patients and prescribing professionals should note that while this compounding formulation presents a great potential for off-label uses, it must always be used considering the specific patient's suitability, taking into account any allergies, other current medications as well as contraindications for each component of the formulation. We encourage patients or health professionals with further questions or unfamiliar with the potential off-label uses of this medication to reach out to us for additional information. We are fully committed to providing in-depth and precise knowledge on our compounded medication formulations.