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Cromolyn Sodium 10%/Estradiol 0.01%/Lidocaine 10% Vaginal Cream

This formulation is a combination of Cromolyn Sodium 10%, Estradiol 0.01%, and Lidocaine 10% in a semisolid cream base. It is dispensed in a tube for easy and accurate application in the vaginal area. Cromolyn Sodium is an anti-inflammatory agent that helps to reduce swelling and irritation. Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body. It is used to treat symptoms of menopause such as hot flashes and vaginal dryness. Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This combination is specifically designed to provide therapeutic effects for specific gynecological conditions.

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Vaginal Cream
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Formula Information

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This formulation is a unique combination of Cromolyn Sodium, Estradiol, and Lidocaine, compounded into a vaginal cream. Cromolyn Sodium is an anti-inflammatory agent that works by preventing the release of substances in the body that cause inflammation. This can help to reduce symptoms such as itching, swelling, and redness in the vaginal area. Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body. It can help to alleviate symptoms of menopause such as dryness, burning, and itching in the vaginal area. Lidocaine is a local anesthetic that works by blocking nerve signals in your body. It can help to numb the vaginal area, providing relief from pain or discomfort.

The cream is dispensed in a tube, which allows for convenient and precise application. It is designed to deliver medication directly to the vaginal area, providing therapeutic effects for specific gynecological conditions. This can include conditions such as vaginal atrophy, vulvodynia, and interstitial cystitis. Vaginal atrophy is a condition that can occur during menopause, where the vaginal walls become thin, dry, and inflamed. Vulvodynia is a chronic pain condition that affects the vulvar area. Interstitial cystitis is a chronic condition causing bladder pressure, bladder pain and sometimes pelvic pain.

It's important to use this medication as directed by your healthcare provider. The cream should be applied topically to the vaginal area, usually once or twice a day or as directed by your healthcare provider. It's also important to continue using the medication even if you feel well. Do not stop using the medication without consulting your healthcare provider, as this could lead to a return of symptoms.

As with any medication, there may be potential side effects. These can include local irritation, burning, itching, or redness at the application site. If these side effects persist or worsen, or if you experience any other side effects, it's important to contact your healthcare provider immediately.

As compounding pharmacists, we are here to answer any questions you may have about this formulation. Whether you're a patient or a prescriber, we're here to provide you with the information you need to make informed decisions about your healthcare. If you have any questions, please don't hesitate to reach out to us at Bayview Pharmacy.

Drug Interactions

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The combination of Cromolyn Sodium, Estradiol, and Lidocaine in a vaginal cream formulation is designed to address specific gynecological conditions. Cromolyn Sodium is an anti-inflammatory agent that can help reduce swelling and irritation. Estradiol, a form of estrogen, can help manage symptoms of menopause such as vaginal dryness and atrophy. Lidocaine is a local anesthetic that can provide temporary relief from pain or discomfort in the vaginal area.

While this formulation can be highly effective, it's important to be aware of potential drug interactions. Cromolyn Sodium may interact with certain drugs such as beta-blockers, calcium channel blockers, and other heart or blood pressure medications. It's important to inform your healthcare provider if you are taking any of these medications. Similarly, Estradiol can interact with certain medications including some antibiotics, antifungal medications, and St. John's wort. It can also interact with certain lab tests, potentially causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Lidocaine, on the other hand, can interact with other local anesthetics and certain antiarrhythmic drugs such as tocainide and mexiletine. Additionally, it's important to note that the absorption of lidocaine can be increased if the cream is applied over a large area of skin, potentially leading to increased side effects. Therefore, it's crucial to use this medication as directed by your healthcare provider.

Furthermore, this formulation should not be used if you have certain medical conditions. Estradiol should not be used in patients with a history of certain cancers such as breast or uterine cancer, and should not be used during pregnancy. Cromolyn Sodium should be used with caution in patients with kidney or liver disease. Lidocaine should not be used in patients with severe heart block or severe reactions to previous lidocaine use.

It's important to discuss your full medical history and all medications you are currently taking with your healthcare provider before starting this treatment. This includes prescription medications, over-the-counter drugs, and any supplements or herbal products. If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. We are here to help ensure your treatment is safe and effective.

How Does it Work

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This unique formulation combines three active ingredients: Cromolyn Sodium, Estradiol, and Lidocaine, each playing a crucial role in treating specific gynecological conditions. The cream is designed to be applied directly to the vaginal area, allowing for targeted treatment and relief of symptoms.

Cromolyn Sodium is an anti-inflammatory agent that works by preventing the release of substances in the body that cause inflammation. In this formulation, it helps to reduce swelling, itching, and irritation in the vaginal area that can be associated with various gynecological conditions. It is particularly effective in managing symptoms of vulvodynia, a chronic pain condition affecting the vulvar area.

Estradiol, a form of estrogen, is a hormone that is naturally produced by the ovaries. It plays a vital role in many functions, including maintaining the health and normal functioning of the female reproductive system. In this formulation, Estradiol is used to treat symptoms of menopause such as vaginal dryness, burning, and irritation. It works by replenishing the estrogen that the body is no longer producing, helping to restore vaginal tissue health and maintain normal pH balance.

Lidocaine is a local anesthetic that works by blocking nerve signals in your body. In this formulation, it is used to provide temporary relief of pain and discomfort in the vaginal area. It works by numbing the treated area, providing immediate relief from symptoms such as burning, itching, and pain. This can be particularly beneficial for conditions such as vulvodynia or for discomfort following surgical procedures.

This formulation is dispensed in a tube, allowing for convenient and precise application. The cream is designed to be applied directly to the vaginal area, ensuring that the medication is delivered exactly where it is needed. This targeted approach helps to maximize the therapeutic effects of the medication while minimizing potential side effects.

As compounding pharmacists, we are able to customize this formulation to meet the specific needs of each patient. This includes adjusting the concentration of each active ingredient, as well as the texture and consistency of the cream, to ensure optimal effectiveness and patient comfort. If you have any questions about this formulation, or if you would like to discuss how it could be customized to meet your specific needs, please do not hesitate to reach out to us at Bayview Pharmacy.

Other Uses

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Aside from treating specific gynecological conditions, this formulation of Cromolyn Sodium 10%/Estradiol 0.01%/Lidocaine 10% Vaginal Cream has several other uses. It comprises Cromolyn Sodium, a mast cell stabilizer that can alleviate symptoms of allergic reactions; estradiol, a form of estrogen that can help in treating conditions involving estrogen deficiency such as menopausal symptoms; and Lidocaine, an anesthetic that can provide relief from pain and discomfort.

This unique combination of active ingredients may also be indicated in certain cases of vaginal inflammation or allergic reactions as the Cromolyn Sodium could prevent the release of substances in the body that cause inflammation. The inclusion of Lidocaine aids in providing temporary relief from pain or discomfort in the vaginal area, which can be beneficial in instances of dyspareunia (painful sexual intercourse) or post-surgical pain. The estradiol in the formulation can help in the symptomatic relief of atrophic vaginitis, a common issue in postmenopausal women due to lower estrogen levels.

The formulation could as well be utilized as an adjunct treatment in certain dermatological conditions involving the vulvar region, such as lichen sclerosus or vulvodynia. These uses, however, are off-label and must be thoroughly discussed with healthcare providers to assess risks and benefits. Notwithstanding, it is important to remember that the application of this cream should be strictly as instructed by a healthcare provider to avoid any potential side effects or complications.

Keep in mind that the decision to use this cream for other indications would depend on the healthcare provider’s clinical judgement based on patient-specific factors. As always, if you have any questions regarding this formulation, its administration, or its other potential uses, please feel free to reach out to us at Bayview Pharmacy. We stand ready and eager to assist.

Frequently Asked Questions

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What is this compounded formulation specifically?

This is a compounded formulation of Cromolyn Sodium 10%/Estradiol 0.01%/Lidocaine 10% Vaginal Cream. It delivers medication specifically to the vaginal area for specific gynecological conditions.

What form does this medication take?

This medication is a semisolid formulation, dispensed in a tube for convenient and precise application in the vaginal area.

What is the function of Cromolyn Sodium in this formulation?

Cromolyn Sodium is an anti-inflammatory agent that helps in reducing swelling and irritation in the vaginal area.

What role does Estradiol play in this medication?

Estradiol is a form of estrogen, a female sex hormone produced by the ovaries. It is essential for maintaining and regulating various functions in the female body, including the health of the vaginal tissue.

Why does this formulation contain Lidocaine?

Lidocaine is a local anesthetic used in this formulation to numb the applied area, providing relief from pain or discomfort associated with specific gynecological conditions.

How should this medication be applied?

This medication should be applied in the vaginal area as directed by your healthcare provider. The semisolid formulation allows for easy and precise application.

Can this medication cause any side effects?

As with any medication, the risk of side effects does exist. If you experience any unusual symptoms or side effects following the use of this formulation, immediately contact your healthcare professional. Common side effects may include irritation or sensitivity at the application site.

Who should use this Cromolyn Sodium/Estradiol/Lidocaine Vaginal Cream?

This medication should be used by women experiencing specific gynecological conditions as diagnosed by a healthcare provider. It is essential to use this medication under the supervision and direction of a healthcare professional.

How can I store this medication?

This medication should be stored in a cool, dry place, away from direct sunlight. Please ensure it is kept out of reach from children and pets.

How often should I apply this compound?

The frequency of application of this medicated cream depends on the instructions from your healthcare provider based on your specific condition. Never use more than the recommended dose without consulting your healthcare provider.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.