Sublingual Semaglutide (generic Ozempic®) now available! Get Started
Dashboard
Formulas

Colchicine 0.5%/Hydroquinone 6% Topical Gel

This formulation is a Colchicine 0.5%/Hydroquinone 6% Topical Gel, a semisolid preparation that is dispensed through a pump mechanism. This design allows for easy and precise application on the skin, ensuring targeted treatment or absorption of the active ingredients. The gel-like consistency of the formulation enhances its usability and effectiveness.

The active ingredients in this formulation, Colchicine and Hydroquinone, are used to treat specific disease states. Colchicine is commonly used for the treatment of gout and other inflammatory conditions, while Hydroquinone is a skin-lightening agent used in the treatment of hyperpigmentation disorders such as melasma, post-inflammatory hyperpigmentation, and age spots.

Want a different strength?
Click the Text Us button below.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Must be E-Prescribed
Get Started
Generate LeafletShow Leaflet
This medication requires a prescription from your doctor
Trusted by 60,357 patients to date.
A group of faces of our past satisfied patients.
A svg symbol of a mortar and pestle with ingredients going in.
Custom made in our compounding labs.
Sliders that show the customization of ingredients.
Personalized treatment for better results.
User with a gear showing the personalization of the formulation.
All strengths and ingredients are tailored to your needs.
This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.
Topical Gel
653ecb6a7cac0e361c91100b
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Dosing Calculator

Get general dosing information for a patient by using this calculator.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Formula Information

A small arrow pointing down

This formulation combines two active ingredients, Colchicine and Hydroquinone, in a topical gel format. Colchicine, a medication primarily used to treat gout, is present at a concentration of 0.5%. It works by decreasing the build-up of uric acid crystals that cause pain in the affected joint. In this formulation, it is used for its anti-inflammatory properties to help reduce swelling and pain on the skin.

Hydroquinone, on the other hand, is a skin-lightening agent present at a concentration of 6%. It is commonly used to treat conditions such as melasma, age spots, and other skin discolorations related to pregnancy, skin trauma, birth control pills, or hormone replacement therapy. Hydroquinone works by decreasing the production and increasing the breakdown of melanin (the pigment in skin that gives it a brown color).

The gel is a semisolid formulation that is dispensed through a pump mechanism. This design allows for easy and precise application on the skin, ensuring that the active ingredients are delivered directly to the area that needs treatment. The gel-like consistency also aids in the absorption of the active ingredients into the skin, enhancing their effectiveness.

It's important to note that while this formulation can be effective in treating certain skin conditions, it should be used under the supervision of a healthcare provider. Potential side effects may include skin irritation, redness, and dryness. In rare cases, prolonged use of hydroquinone may result in a condition known as ochronosis, which causes darkening of the skin. Therefore, it's crucial to follow the prescribed dosage and duration of treatment.

As compounding pharmacists, we are committed to providing personalized medication solutions to meet the unique needs of each patient. If you have any questions about this formulation or how it can be used to treat specific skin conditions, please don't hesitate to reach out to us at Bayview Pharmacy. We are here to help.

Drug Interactions

A small arrow pointing down

Colchicine and Hydroquinone are two active ingredients in this topical gel formulation. Colchicine is an anti-inflammatory agent primarily used to treat gout and other inflammatory conditions, while Hydroquinone is a skin-lightening agent used to treat hyperpigmentation disorders such as melasma, post-inflammatory hyperpigmentation, and age spots.

When using this formulation, it's important to be aware of potential drug interactions. Colchicine can interact with certain medications such as statins, cyclosporine, and certain antibiotics like clarithromycin and erythromycin, which can increase the risk of serious or life-threatening side effects such as muscle weakness and kidney damage. If you are taking any of these medications, please inform your healthcare provider.

Hydroquinone, on the other hand, can interact with benzoyl peroxide, hydrogen peroxide, or other peroxide products. These interactions can cause a temporary staining of the skin which can be removed by cleansing. It's recommended to avoid using any products containing peroxides while using Hydroquinone.

Furthermore, both Colchicine and Hydroquinone can interact with certain substances that may be present in other topical products. For instance, the use of topical products containing alcohol, astringents, spices, or lime should be avoided because they may cause skin dryness or irritation. Also, the use of medicated or abrasive soaps and cleansers, soaps and cosmetics with a strong drying effect, and products with high concentrations of alcohol, astringents, spices, or lime should be avoided.

It's also important to note that both Colchicine and Hydroquinone can increase your skin's sensitivity to sunlight, making you more prone to sunburn. Therefore, it's recommended to limit your sun exposure and use a sunscreen and protective clothing when outdoors.

This formulation is intended for topical use only and should not be used on broken or irritated skin. It should also not be used near the eyes, nose, or mouth. If the medication gets into these areas, rinse thoroughly with water.

As always, before starting any new medication, it's important to discuss with your healthcare provider about all the medications, supplements, and topical products you are currently using to avoid any potential drug interactions. If you have any questions or concerns about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. We are here to help.

How Does it Work

A small arrow pointing down

The Colchicine 0.5%/Hydroquinone 6% Topical Gel is a unique formulation that combines the anti-inflammatory properties of Colchicine with the skin-lightening effects of Hydroquinone. This combination is designed to provide targeted treatment for a variety of skin conditions.

Colchicine, the first active ingredient, is a medication traditionally used to treat gout and other inflammatory conditions. In this formulation, it works by decreasing the build-up of uric acid crystals that cause pain in the affected joint. It also has anti-inflammatory properties that can help to reduce swelling and redness. When applied topically, Colchicine can provide targeted relief to specific areas of inflammation on the skin.

The second active ingredient, Hydroquinone, is a skin-lightening agent. It works by decreasing the production and increasing the breakdown of melanin pigments in the skin. This can help to lighten areas of darkened skin such as freckles, age spots, melasma, and other skin discolorations caused by hormone medication, injury to the skin, or prolonged sun exposure. Hydroquinone is a potent ingredient and its use should be carefully monitored by a healthcare professional.

The gel formulation allows for easy and precise application of the medication. The semisolid consistency of the gel ensures that the active ingredients remain on the skin surface for a sufficient amount of time to exert their effects. The pump mechanism of the dispenser allows for controlled and consistent dosing, ensuring that the correct amount of medication is applied each time.

It's important to note that while this formulation can provide significant benefits, it may also cause side effects such as mild burning, stinging, redness, and dryness of the skin. If these side effects persist or worsen, it's important to contact your healthcare provider. Also, this medication should be used under the supervision of a healthcare professional due to the potential for skin irritation and discoloration.

If you have any questions about the Colchicine 0.5%/Hydroquinone 6% Topical Gel, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

A small arrow pointing down

Colchicine 0.5%/Hydroquinone 6% Topical Gel is commonly used as a topical treatment for various skin conditions. This cream is highly beneficial for managing diseases such as gout, familial Mediterranean fever, or Behçet's disease due to its anti-inflammatory properties and potent effect on uric acid crystals. It works by reducing the build-up of uric acid crystals that cause pain in the affected joint. This gel-like consistency when applied facilitates easy and controlled application, ensuring the medication is concentrated in the area where it is needed, and minimizing systemic side effects.

This high-potency formulation can also be beneficial for skin discoloration conditions due to its Hydroquinone constituents. Hydroquinone is indeed recognized for its hypopigmenting capabilities. Particularly in cases of melasma, freckles, or post-inflammatory hyperpigmentation, this topical cream can correct skin tone disparities, leading to more even-toned skin. Its precision application through a pump mechanism enhances its therapeutic effects by confining the medicine to the discolored area, more so when used with a comprehensive skincare regimen, including sun protection.

Another auxiliary use of this topical gel is in the symptomatic alleviation of the condition called dermatitis herpetiformis, an itchy, blistering skin rash that can occur as a result of celiac disease. Colchicine's active components are known to reduce inflammation and cut down on the immunological response that contributes to such conditions. While this is not a first-line treatment, it may be beneficial for some patients under their healthcare provider's guidance. It is essential to apply this medication as instructed to limit potential side effects.

Always consult your healthcare provider before using Colchicine 0.5%/Hydroquinone 6% Topical Gel for any unlisted condition or symptoms. The dosage and frequency of this formulation may differ based on individual factors such as the severity of the condition, the individual's sensitivity to the medication, age, and general health status.

If you have any questions about this product or its uses, we encourage you to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always ready to assist with medication-related inquiries to ensure effective and safe personalized treatment.

Frequently Asked Questions

A small arrow pointing down

What is this compounded formulation of Colchicine 0.5%/Hydroquinone 6% Topical Gel?

This is a specific type of medication that combines the active ingredients Colchicine and Hydroquinone. The mixture is created in a gel-like form facilitating easy and precise application on the skin for targeted treatments.

How to apply this compounded formulation?

This compounded formulation is dispensed through a pump mechanism which facilitates easy application. Apply a small amount on the affected area as prescribed by your doctor or pharmacist.

Who might need this type of medication?

Anyone who has been prescribed by their healthcare provider for specific skin conditions that can be treated with the active ingredients Colchicine and Hydroquinone.

Can this medication be used for all skin types?

Most skin types should be able to tolerate this medication. However, individual results can vary based on skin sensitivity and the nature of the skin condition. Always consult your doctor or dermatologist before use.

Is this gel formulation safe?

Yes, this gel formulation is generally safe when used as prescribed. However, likes any medication it can have potential side effects. Therefore, use it under the guidance and prescription of a healthcare provider.

What to do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not apply extra doses to make up for a missed dose unless directed by your healthcare provider.

What should I do if I experience any side effects?

If you experience any side effects, no matter how minor they may seem, immediately discontinue use and contact your healthcare provider for guidance.

Can this medication be used with other topical products?

Before combining this formulation with other topical products, it is advised to consult your healthcare provider to avoid any potential adverse interactions.

Does the pump ensure an accurate dosage?

Yes, the pump mechanism is designed to provide a fixed dose of medication per pump to ensure accurate and consistent dosing each time.

Is there any special storage requirements for the compounded formulation of Colchicine 0.5%/Hydroquinone 6% Topical Gel?

Store this medication at room temperature away from heat, light and moisture. Always ensure the cap is tightly closed after each usage to maintain the efficacy of the medication. Find more details on the packaging.

Related Formulas

Related Products
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.