This formulation is a topical cream containing 2% Coal Tar and 5% Pentoxifylline, dispensed in a pump mechanism for easy and controlled application. The cream is designed to be applied directly to the skin, allowing for localized treatment and absorption of the active ingredients. This formulation is particularly beneficial for patients suffering from certain skin conditions, as it combines the therapeutic benefits of both Coal Tar and Pentoxifylline.

Coal Tar, a byproduct of coal processing, has been used for centuries to treat a variety of skin conditions. It works by slowing the rapid growth of skin cells, reducing inflammation, itching, and scaling. This makes it particularly effective in the treatment of psoriasis, eczema, and other similar skin conditions. However, it's important to note that Coal Tar can cause skin irritation and staining of clothes and bedding, so it should be used with caution.

Pentoxifylline, on the other hand, is a xanthine derivative that improves blood flow and reduces inflammation. It's often used to treat peripheral vascular diseases and has been found to be effective in treating venous leg ulcers. When used in a topical cream, Pentoxifylline can help to reduce inflammation and promote healing in the affected area.

Together, Coal Tar and Pentoxifylline provide a potent combination for treating a variety of skin conditions. The cream formulation allows for direct application to the affected area, providing targeted relief and promoting healing. However, as with any medication, it's important to use this product as directed by a healthcare professional. Side effects can include skin irritation, redness, and staining of clothes and bedding. If you experience any severe or persistent side effects, you should contact your healthcare provider immediately.

As compounding pharmacists, we are here to answer any questions you may have about this formulation. Whether you're a patient or a prescriber, we're happy to provide more information and guidance. Please don't hesitate to reach out to us if you have any questions or concerns.

Coal Tar 2%/Pentoxifylline 5% Topical Cream is a unique formulation designed to treat a variety of skin conditions. Coal tar, a byproduct of coal processing, has been used for centuries to alleviate itching, scaling, and inflammation associated with conditions such as psoriasis and eczema. Pentoxifylline, on the other hand, is a xanthine derivative that improves blood flow and reduces inflammation, making it useful in treating conditions like peripheral vascular disease and venous leg ulcers.

While this formulation is generally safe for most patients, there are potential drug interactions that prescribers and patients should be aware of. Coal tar can potentially interact with drugs that increase sensitivity to sunlight, such as certain antibiotics (e.g., tetracyclines), water pills (diuretics), and sulfa drugs. Increased sun sensitivity could lead to a severe sunburn. Therefore, it is recommended to limit sun exposure and use sunscreen while using this formulation.

Pentoxifylline, on the other hand, can interact with anticoagulants (blood thinners) like warfarin, increasing the risk of bleeding. It can also interact with antiplatelet drugs like clopidogrel, and nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, which can further increase the risk of bleeding. Therefore, patients on these medications should use this formulation with caution and under the supervision of a healthcare provider.

Furthermore, pentoxifylline can lower blood pressure, so it may interact with antihypertensive drugs, potentially causing blood pressure to drop too low. Patients on blood pressure medications should monitor their blood pressure regularly while using this formulation.

It's also important to note that both coal tar and pentoxifylline can interact with alcohol. Alcohol can enhance the skin's sensitivity to coal tar, increasing the risk of sunburn. It can also increase the risk of side effects from pentoxifylline, such as dizziness and flushing. Therefore, it is recommended to limit or avoid alcohol consumption while using this formulation.

As with any medication, it's important to discuss all current medications, including over-the-counter drugs and dietary supplements, with a healthcare provider before starting this formulation. This will help to identify any potential drug interactions and ensure the safe and effective use of this medication.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

The Coal Tar 2%/Pentoxifylline 5% Topical Cream is a specially formulated semisolid preparation that is dispensed through a pump mechanism. This design allows for convenient and controlled application on the skin, ensuring that the active ingredients are localized for treatment or absorption. The cream contains two active ingredients: coal tar and pentoxifylline, each with its unique therapeutic properties.

Coal tar, a byproduct of coal processing, has been used for centuries to treat various skin conditions. It works by slowing down the growth of skin cells, reducing inflammation and scaling, and relieving itching. This makes it particularly effective in treating conditions like psoriasis and eczema, where rapid skin cell turnover and inflammation are common symptoms. Coal tar also has mild antiseptic properties, which can help prevent infection in damaged skin.

Pentoxifylline, on the other hand, is a xanthine derivative that works by improving blood flow and reducing inflammation. It achieves this by increasing the flexibility of red blood cells, reducing blood viscosity, and inhibiting inflammatory responses. This makes it useful in treating conditions like peripheral vascular disease and venous leg ulcers, where improved blood flow can aid in healing. In a topical formulation like this cream, pentoxifylline can help deliver oxygen and nutrients to the skin, promoting healing and reducing inflammation.

When combined in this formulation, coal tar and pentoxifylline work synergistically to treat a variety of skin conditions. The coal tar slows down skin cell growth and reduces inflammation, while the pentoxifylline improves blood flow and further reduces inflammation. This dual-action approach can provide significant relief for patients suffering from conditions like psoriasis, eczema, and venous leg ulcers.

As with any medication, it's important to use this cream as directed by your healthcare provider. Apply a thin layer to the affected area, usually once or twice daily or as directed by your doctor. Avoid contact with the eyes, nose, or mouth, and wash your hands thoroughly after applying. If you have any questions about this formulation or how to use it, don't hesitate to reach out to us at Bayview Pharmacy. We're here to help.

Coal Tar 2%/Pentoxifylline 5% Topical Cream is primarily used to manage and treat various skin conditions such as psoriasis, atopic dermatitis, and seborrheic dermatitis. Its dual action serves to alleviate symptoms and slow the progress of these conditions. However, this formulation also provides some additional benefits.

Besides its primary indications, Coal Tar has been known to offer symptomatic relief in other dermal conditions marked by itching, flaking, and inflammation. It may also be beneficial in the management of other forms of eczema and chronic itching conditions. The potent anti-pruritic, anti-inflammatory, and keratolytic actions of Coal Tar make it suitable for adjunctive use in other chronic skin disorders marked by hyperkeratosis and desquamation.

Pentoxifylline, on the other hand, has been traditionally used in peripheral vascular diseases and cerebrovascular disease due to its action to increase blood flow. While its use in a topical application is less common, there are studies that show a potential role of topical Pentoxifylline in wound healing, particularly in cases where microcirculation has been compromised, such as venous ulcers, pressure ulcers, diabetic ulcers, and potentially in vasculitic ulcers.

Coal Tar 2%/Pentoxifylline 5% Topical Cream aims to combine the strengths of these two active ingredients and may potentially serve as a supportive adjunct in various skin and wound treatment protocols under the guidance of a healthcare professional.

Please note that different patients may react differently to the same formulation and that the decision to prescribe this cream should depend on the clinician's judgment and the patient's specific medical condition and history. Meanwhile, patients are encouraged to discuss potential benefits, risks, and contraindications with their clinician, prior to starting this or any other medication or therapy.

If you're a health professional interested in prescribing this formulation, or a patient considering using it, we strongly recommend reaching out to us. We have highly experienced and knowledgeable compounding pharmacists on our team at Bayview Pharmacy who are always available to answer any of your queries regarding the use and application of this formulation.