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Formulas

Clotrimazole 0.33%/Hydrocortisone 0.33%/Zinc Oxide 3.3% Topical Cream

This formulation is a semisolid preparation of Clotrimazole 0.33%, Hydrocortisone 0.33%, and Zinc Oxide 3.3% Topical Cream, dispensed in a pump mechanism for easy and controlled application. The cream is designed for localized treatment on the skin, facilitating the absorption of active ingredients.

Clotrimazole is an antifungal medication used to treat skin infections such as athlete's foot, jock itch, and ringworm. Hydrocortisone is a corticosteroid that reduces swelling, itching, and redness that can occur with these conditions. Zinc Oxide is an astringent that creates a protective barrier on the skin, promoting healing and soothing irritated skin.

This formulation is specifically used to treat various skin conditions including fungal infections, inflammation, and irritation. It provides relief from symptoms associated with these conditions, promoting healing and comfort.

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Topical Cream
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Formula Information

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This formulation is a compounded topical cream containing Clotrimazole 0.33%, Hydrocortisone 0.33%, and Zinc Oxide 3.3%. It is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. This formulation is intended for localized treatment or absorption of active ingredients.

Clotrimazole is an antifungal medication that works by stopping the growth of fungus. It is commonly used to treat skin infections such as athlete's foot, jock itch, ringworm, and yeast infections. Hydrocortisone is a corticosteroid that reduces redness, itching, and swelling. It is often used to treat a variety of skin conditions including eczema, dermatitis, allergies, and rash. Zinc Oxide is a skin protectant that forms a barrier on the skin to protect against irritation and moisture. It is often used in treating minor skin irritations such as burns, cuts, and diaper rash.

This combination of active ingredients makes the formulation effective in treating a variety of skin conditions. The antifungal properties of Clotrimazole, the anti-inflammatory and itch-relieving properties of Hydrocortisone, and the skin-protecting properties of Zinc Oxide work together to provide relief from various skin conditions. The pump mechanism allows for easy and controlled application of the cream, ensuring that the right amount of medication is applied to the affected area.

Patients using this formulation should follow the directions provided by their healthcare provider. The cream should be applied to the affected area as directed, usually once or twice daily. It is important to continue using the medication for the full treatment time recommended by the healthcare provider, even if symptoms disappear after a few days. Stopping the medication too early may allow the fungus to continue to grow, which may result in a return of the infection.

Prescribers should consider the patient's medical history, current medications, and potential drug interactions when prescribing this formulation. Patients with a history of allergic reactions to any of the active ingredients should not use this formulation. Additionally, prescribers should monitor the patient's response to treatment and adjust the dosage or frequency of application as necessary.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to assist you.

Drug Interactions

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This formulation combines the antifungal properties of clotrimazole, the anti-inflammatory and itch-relieving properties of hydrocortisone, and the skin-protecting and astringent properties of zinc oxide. It is designed to treat a variety of skin conditions, including fungal infections, eczema, dermatitis, and minor skin irritations. The cream is dispensed via a pump mechanism for easy and controlled application.

Clotrimazole, as an antifungal agent, works by inhibiting the growth of fungus on the skin. It is important to note that clotrimazole can interact with certain medications. For instance, it can increase the blood levels and effects of tacrolimus, a medication used to prevent organ transplant rejection. This can lead to serious side effects such as kidney problems, high blood pressure, or nervous system problems. Therefore, if you are taking tacrolimus or similar medications, inform your healthcare provider before using this cream.

Hydrocortisone, a corticosteroid, reduces redness, itching, and swelling. It can interact with certain medications, including some vaccines. It may decrease the body's immune response to these vaccines, making them less effective. Therefore, if you are scheduled for a vaccination, inform your healthcare provider before using this cream. Also, using hydrocortisone with certain medications that lower the immune system can increase the chances of getting an infection.

Zinc oxide is a skin protectant that forms a barrier on the skin to protect it from irritants and moisture. It is generally considered safe and does not typically interact with other medications. However, it can cause a minor skin irritation in some people. If you experience any unusual skin reactions after using this cream, stop using it and contact your healthcare provider.

It is important to use this cream as directed by your healthcare provider. Do not use it more often or for a longer period than recommended. This can increase the risk of side effects. Also, avoid using this cream on broken or infected skin unless directed by your healthcare provider. If your condition does not improve or if it worsens after using this cream, contact your healthcare provider.

If you have any questions about this formulation or its use, please reach out to us at Bayview Pharmacy. We are a team of knowledgeable compounding pharmacists who are here to help you.

How Does it Work

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This formulation combines three active ingredients: Clotrimazole, Hydrocortisone, and Zinc Oxide, each with a unique mechanism of action to treat a variety of skin conditions. The cream is designed to be easily applied to the skin, with a pump mechanism for controlled dispensing.

Clotrimazole is an antifungal medication that works by inhibiting the growth of fungus. It does this by interfering with the production of the fungal cell membrane. The cell membrane of a fungus is crucial for its survival. It keeps unwanted substances from entering the cells and stops the contents of the cells from leaking out. By disrupting the cell membrane, Clotrimazole causes the contents of the fungal cells to leak out, which kills the fungi and treats the infection.

Hydrocortisone is a corticosteroid that works by decreasing the body's immune response to reduce symptoms such as swelling, redness, and itching. It does this by blocking the release of certain chemicals in the body that cause inflammation. This helps to reduce the redness, swelling and itching associated with skin conditions such as eczema, dermatitis, and allergic reactions.

Zinc Oxide is a skin protectant that provides a barrier on the skin to protect it from irritants and to help soothe and heal the skin. It works by forming a physical barrier on the skin to protect against irritants and to help keep the area moist. This barrier helps to promote the healing of the skin and to reduce symptoms such as itching and redness.

This combination of ingredients makes the cream effective for treating a variety of skin conditions, including fungal infections, inflammation, and irritation. The cream is designed to be easily applied to the skin, with a pump mechanism for controlled dispensing. This allows for precise application of the cream to the affected area, ensuring that the active ingredients are delivered where they are needed most.

If you have any questions about this formulation, or how to use it, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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This formulation of Clotrimazole 0.33%/Hydrocortisone 0.33%/Zinc Oxide 3.3% Topical Cream is primarily utilized for its antifungal, anti-inflammatory, and skin-protective properties. Besides the specific disease states for which it's ordinarily prescribed, this cream can potentially have other therapeutic uses.

Due to its clotrimazole component, an antifungal medication, it might be used off-label for a broader variety of fungal skin infections than those it is typically prescribed for. This could include alternative kinds of cutaneous mycoses that aren't ordinarily treated with this formulation. The hydrocortisone, a corticosteroid, assists in reducing redness, itching, and swelling, making it potentially beneficial for a variety of skin conditions characterized by inflammation and itchiness, such as eczema, dermatitis, or insect bites. However, it is essential to consult with a healthcare provider before using it in this way, as long-term or inappropriate use of topical corticosteroids can lead to skin thinning and other side effects.

Zinc oxide, the third ingredient, provides a barrier for the skin and promotes healing, which could make the cream helpful for minor skin irritations and wounds. While zinc oxide is widely recognized for its use in diaper rash creams, in combination with the other ingredients in this formulation, it could potentially be beneficial for other minor skin irritations or wounds. Its astringent properties can help soothe the skin and reduce excess oils, potentially making it beneficial for acne treatment.

It's significantly crucial to remember that while these other uses can be potential avenues for the application of this cream, the combination's safety and efficacy for these uses may not be as extensively studied or established as for its primary uses. Therefore, it's always a good idea to consult a healthcare professional before using this or any medication in a way it wasn't initially prescibed. While we aim to provide comprehensive and accurate information, please reach out to us at Bayview Pharmacy if you have any questions or need further clarification. Our team of compounding pharmacists is readily accessible to assist with any of your inquiries or concerns.

Frequently Asked Questions

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What is this compounded formulation of Clotrimazole 0.33%/Hydrocortisone 0.33%/Zinc Oxide 3.3% Topical Cream?

This is a specially formulated topical cream made up of Clotrimazole, Hydrocortisone and Zinc Oxide. These active ingredients are designed to be absorbed by the skin for localized treatment of various skin conditions.

What type of skin conditions can this topical cream treat?

While your physician can prescribe this cream for any number of skin conditions, commonly it is used to treat fungal infections, inflammation, and barrier protection or skin irritation due to its main components Clotrimazole, Hydrocortisone, and Zinc Oxide respectively.

What is the role of Clotrimazole in the formulation?

Clotrimazole is an azole antifungal agent. It works by stopping the growth of fungus and is therefore effective in treating skin thrush and ringworm, among other fungal infections.

What does Hydrocortisone do in the cream?

Hydrocortisone is a corticosteroid and it works by reducing skin irritation and inflammation. This makes it useful for ailments like eczema and dermatitis.

Why is Zinc Oxide included in the formula?

Zinc oxide is known for its healing properties. It can create a protective barrier on the skin, preventing moisture and irritants from further aggravating the skin. It also has mild astringent properties and has some antiseptic action.

How should this cream be used?

The cream should be applied topically, directly to the affected area of the skin. It is engineered for a convenient and controlled application with a pump mechanism, ensuring that the right amount is used.

Can anyone use this cream?

This cream can be used by most individuals. However, it is always necessary to consult with your doctor, especially if you are pregnant, breastfeeding, or have any underlying medical conditions. Also, make sure to check for potential allergies to any of the ingredients in the compound.

What do I do in case of an allergic reaction?

If you experience any allergic reactions, such as rashes, itching, or swelling, discontinue use immediately and consult your healthcare provider.

How should I store this cream?

It should be stored at room temperature, away from heat, light, and moisture. It should also be kept out of reach of children and pets.

Can I use the cream past its expiry date?

No, you should not use the cream past its expiry date. The efficacy of the active ingredients may decrease over time, and it may not be as effective in treating your condition.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.