This formulation is a compounded transdermal gel containing Clonidine HCl 0.3%, Gabapentin 6%, Ketamine HCl 5%, and Ketoprofen 5%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency of the formulation ensures that the active ingredients are absorbed directly into the targeted area, providing localized treatment.

Clonidine HCl is an alpha-2 adrenergic agonist that is commonly used to treat high blood pressure. In this formulation, it is used for its potential analgesic properties and its ability to reduce certain symptoms of withdrawal from opioids. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat seizures and pain caused by shingles. In this formulation, it is used for its potential to alleviate neuropathic pain.

Ketamine HCl is a powerful anesthetic that is used in both human and veterinary medicine. In this formulation, it is used for its potential to provide relief from chronic pain, particularly in cases where other treatments have failed. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to relieve pain, reduce inflammation, and lower fever. In this formulation, it is used for its potential to reduce inflammation and relieve pain.

This formulation is designed to treat a variety of disease states, including chronic pain conditions, neuropathic pain, and certain symptoms of opioid withdrawal. The combination of these four active ingredients provides a multi-modal approach to pain management, addressing different aspects of pain and inflammation to provide comprehensive relief. As a transdermal gel, it offers the advantage of targeted treatment, delivering the active ingredients directly to the area where they are needed most.

It is important for patients and prescribers to understand that this is a compounded medication, meaning it is made specifically for the patient based on a doctor's prescription. It is not a commercially available product and should only be used under the supervision of a healthcare professional. As with any medication, it may have potential side effects and interactions, so it is important to discuss these with your healthcare provider.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide you with the information and support you need.

This formulation combines Clonidine HCl, Gabapentin, Ketamine HCl, and Ketoprofen in a transdermal gel. Each of these active ingredients has its own potential for drug interactions, which can be amplified when used in combination. It's important for patients and prescribers to be aware of these potential interactions to ensure safe and effective use of this formulation.

Clonidine HCl is an alpha-2 adrenergic agonist that can interact with other central nervous system depressants, such as alcohol, barbiturates, or benzodiazepines, leading to an increased risk of sedation and respiratory depression. It can also interact with beta-blockers, potentially causing bradycardia and hypotension. Furthermore, abrupt discontinuation of Clonidine while taking beta-blockers may increase the risk of rebound hypertension.

Gabapentin's absorption can be affected by antacids containing magnesium or aluminum, so it's recommended to separate the administration of these medications by at least two hours. Gabapentin can also increase the effects of other drugs that cause sedation, including opioids, antihistamines, and alcohol.

Ketamine HCl is a NMDA receptor antagonist that can interact with other central nervous system depressants, leading to an increased risk of respiratory depression, hypotension, profound sedation, and potentially coma. Concurrent use with monoamine oxidase inhibitors (MAOIs) can lead to a hypertensive crisis.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can interact with anticoagulants, increasing the risk of bleeding. It can also interact with other NSAIDs, leading to an increased risk of gastrointestinal bleeding. Concurrent use with angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), or beta-blockers can reduce their antihypertensive effect. Furthermore, concurrent use with lithium can increase lithium levels, leading to toxicity.

This formulation is designed to provide targeted treatment for various disease states. Clonidine HCl can help manage hypertension and severe pain. Gabapentin is used to treat nerve pain and seizures. Ketamine HCl can provide pain relief and has been used in the management of depression. Ketoprofen can reduce inflammation and pain. However, the combined use of these medications in a transdermal gel allows for targeted application, potentially reducing systemic side effects and improving patient compliance.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us. We're here to provide the information you need to ensure safe and effective treatment.

This formulation combines four active ingredients: Clonidine HCl, Gabapentin, Ketamine HCl, and Ketoprofen, each with a unique mechanism of action to provide a comprehensive approach to pain management. The formulation is designed to be applied topically, directly to the skin, where it is absorbed into the body to provide targeted relief.

Clonidine HCl is an alpha-2 adrenergic agonist that works by stimulating receptors in the brain that reduce nerve signal transmission. This results in a decrease in the sensation of pain. Gabapentin, on the other hand, is an anticonvulsant and nerve pain medication. It is believed to work by affecting the way the body senses pain. It is particularly effective in treating nerve pain caused by shingles and diabetes, as well as certain types of seizures.

Ketamine HCl is a powerful anesthetic that works by blocking the NMDA receptors in the brain, which are involved in pain signaling. This effectively reduces the perception of pain. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is commonly used to relieve pain, swelling, and joint stiffness caused by arthritis.

The transdermal gel formulation allows for the active ingredients to be absorbed through the skin directly into the bloodstream. This provides targeted relief to the area where the gel is applied, and allows for a more controlled release of the medication. The pump mechanism of the dispenser ensures that the correct dose is applied each time, reducing the risk of overdose or underdose.

This formulation is particularly effective in treating various disease states that involve chronic pain, such as neuropathic pain, fibromyalgia, and certain types of arthritis. By combining four different active ingredients, it provides a comprehensive approach to pain management that targets different aspects of the pain pathway. This can result in more effective pain relief than would be achieved with a single medication.

If you have any questions about this formulation, or how it may be beneficial in treating your specific condition, please do not hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.

This medication, containing Clonidine HCl, Gabapentin, Ketamine HCl, and Ketoprofen, delivered in a semisolid transdermal gel formulation, is typically used to manage and treat chronic pain, neuropathic pain, and arthritis. In addition to these common uses, it may also be employed for other clinical purposes.

Given the antinociceptive properties of Gabapentin, this medication might be beneficial for those suffering from Postherpetic Neuralgia (PHN), as it can alleviate the burning sensations typically associated with this neuropathic pain condition. Furthermore, Gabapentin in this compound may help to manage restless leg syndrome and hot flashes, as research has indicated it can ameliorate these conditions.

Also present in the gel is Clonidine HCl, a medication that is beneficial in treating high blood pressure, which suggests it could be used to manage hypertension. As Clonidine HCl has been utilized in ADHD treatment, it could potentially also provide some benefit for patients with this disorder.

Ketamine HCl, a well-known anaesthetic, contributes to the compound's multifaceted applicability. When Ketamine HCl is used topically, it may benefit patients with mast cell activation syndrome and fibromyalgia by relieving pain.

The inclusion of Ketoprofen in the transdermal gel, traditionally used to treat pain, inflammation and stiffness caused by arthritis, extends its potential benefits to sports injuries, acute gout attacks, and acute bursitis.

Despite these potential other uses, it's crucial to note that utilization of this compound would be considered off-label for anything other than chronic pain, neuropathic pain, and arthritis. As such, it is strongly encouraged to consult with a healthcare provider or compounding pharmacist before considering this formulation for other indications. A full discussion of potential benefits, risks, and side effects is necessary when contemplating this compound's use outside of its typical indications.

If there are any further questions or enquiries about this formulation or its potential other uses, please, do not hesitate to reach out to us. We, at Bayview Pharmacy, are here to clarify any doubts and ensure the compound is used safely and effectively.