This formulation is a compounded topical gel containing Clonidine HCl 0.232%, Gabapentin 8%, Ketamine HCl 5.75%, and Lidocaine HCl 10%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency of the formulation ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

Clonidine HCl is a medication that is primarily used to treat high blood pressure, but in this formulation, it is used for its potential analgesic and anti-inflammatory properties. It can help to reduce pain and inflammation in the area where the gel is applied. Gabapentin is a medication that is commonly used to treat nerve pain and seizures. In this formulation, it is used for its analgesic properties, helping to reduce nerve pain in the area where the gel is applied.

Ketamine HCl is a medication that is primarily used as a general anesthetic, but in this formulation, it is used for its analgesic and anti-inflammatory properties. It can help to reduce pain and inflammation in the area where the gel is applied. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. In this formulation, it is used to provide temporary relief from pain and discomfort in the area where the gel is applied.

This formulation is typically used to treat conditions that cause chronic pain, such as neuropathic pain, post-herpetic neuralgia, and fibromyalgia. It can also be used to treat conditions that cause acute pain, such as post-surgical pain, burns, and injuries. The combination of these four active ingredients provides a multi-modal approach to pain management, targeting different pain pathways to provide comprehensive pain relief.

As with any medication, this formulation should be used as directed by a healthcare provider. It is important to apply the gel only to the area of skin that has been prescribed by the healthcare provider, and to avoid contact with the eyes, mouth, and other mucous membranes. If you have any questions about this formulation, please reach out to us at Bayview Pharmacy. We are a team of knowledgeable compounding pharmacists who are here to help.

This compounded formulation contains Clonidine HCl, Gabapentin, Ketamine HCl, and Lidocaine HCl. Each of these active ingredients has its own potential for drug interactions, which can be amplified when used in combination. It is crucial for patients and prescribers to be aware of these potential interactions to ensure safe and effective use of this medication.

Clonidine HCl is an alpha-2 adrenergic agonist that can interact with other central nervous system depressants, such as alcohol, barbiturates, or benzodiazepines, leading to an increased risk of sedation and respiratory depression. It can also interact with beta-blockers, potentially causing bradycardia or hypotension. If a patient is taking any of these medications, they should inform their healthcare provider.

Gabapentin, an anticonvulsant and nerve pain medication, can interact with antacids containing magnesium or aluminum, as they can reduce the absorption of gabapentin, leading to decreased effectiveness. It can also increase the effects of other central nervous system depressants, such as opioids or sedatives, potentially leading to increased sedation or respiratory depression.

Ketamine HCl, a potent anesthetic, can interact with other central nervous system depressants, leading to an increased risk of sedation, respiratory depression, and potentially profound hypotension. It can also interact with monoamine oxidase inhibitors (MAOIs), potentially leading to a hypertensive crisis. Patients taking any of these medications should inform their healthcare provider.

Lidocaine HCl, a local anesthetic, has fewer systemic interactions due to its local application. However, it can interact with other local anesthetics or medications with similar metabolic pathways, potentially leading to increased systemic absorption and toxicity. Patients should inform their healthcare provider if they are using any other local anesthetics.

This formulation is designed to provide targeted treatment for various disease states, including neuropathic pain, post-herpetic neuralgia, and complex regional pain syndrome. The combination of these medications works synergistically to provide pain relief, reduce inflammation, and improve nerve function. However, due to the potential for drug interactions, it is crucial for patients and prescribers to be aware of all medications the patient is currently taking, including over-the-counter medications and supplements. If you have any questions or concerns about potential drug interactions, please reach out to us at Bayview Pharmacy. We are here to help ensure the safe and effective use of this medication.

This formulation combines four active ingredients: Clonidine HCl, Gabapentin, Ketamine HCl, and Lidocaine HCl, each with a unique mechanism of action to provide relief from various disease states. The formulation is designed to be applied topically, directly to the skin, where it can be absorbed to provide targeted treatment.

Clonidine HCl is a medication that is primarily used to treat high blood pressure, but in this formulation, it is used for its pain-relieving properties. It works by stimulating alpha-2 adrenergic receptors in the brain, which helps to decrease nerve signal transmission and thus reduce pain sensation. The concentration of Clonidine HCl in this formulation is 0.232%.

Gabapentin is a medication that is primarily used to treat seizures and nerve pain. It works by affecting the chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. The concentration of Gabapentin in this formulation is 8%.

Ketamine HCl is a medication that is primarily used for starting and maintaining anesthesia. It induces a trance-like state while providing pain relief, sedation, and memory loss. In this formulation, it is used for its analgesic properties. It works by blocking the NMDA receptors in the brain, which play a key role in pain sensation. The concentration of Ketamine HCl in this formulation is 5.75%.

Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It works by blocking nerve signals in your body. The concentration of Lidocaine HCl in this formulation is 10%.

The formulation is a semisolid gel that is dispensed through a pump mechanism. This allows for easy and precise application on the skin. The gel-like consistency ensures that the medication stays where it is applied, allowing for targeted treatment and absorption of the active ingredients.

This formulation can be used to treat a variety of disease states, including neuropathic pain, post-herpetic neuralgia, allodynia, and other conditions where the combined action of these four medications can provide relief. As always, it is important to use this medication under the guidance of a healthcare provider, and to discuss any questions or concerns you may have with them. If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy.

This compounding gel formulation containing Clonidine HCl, Gabapentin, Ketamine HCl, and Lidocaine HCl commonly treats nerve pain or neuropathy, post-herpetic neuralgia, and other types of chronic pain. However, it also has other less common but notable uses. The individual ingredients in this compounding formulation provide unique therapeutic aspects, potentially beneficial for a variety of other conditions.

For instance, Lidocaine is a local anesthetic that numbs the skin and surrounding tissues, often used for relieving itching, burning, and pain from skin inflammations. Further, Lidocaine is beneficial for temporary relief of pain and discomfort associated with hemorrhoids and other anorectal disorders.

Clonidine, an agent that primarily treats hypertension, is also used off-label for withdrawal symptoms from opioids, alcohol, nicotine, and benzodiazepines. In some cases, it may be useful as an alternative to traditional medication for attention deficit hyperactivity disorder (ADHD).

Furthermore, Gabapentin, commonly used for neuropathic pain, may also serve other purposes. It can be essential in managing restless legs syndrome, postherpetic neuralgia, and a certain type of seizure condition. Also, Gabapentin may be used to help control anxiety and to ease certain kinds of pain.

Ketamine, originally used as an anesthetic, may have potential benefits in treating depression, particularly treatment-resistant depression, though this use remains exploratory and is not routinely recommended.

Patients considering this formulation should remember that a significant advantage of topical application is the ability to deliver the active ingredients directly to the area of discomfort while minimizing systemic exposure and reducing potential side effects. However, it's critical to use under direction by a healthcare professional, as this combination can lead to serious side effects if not used correctly.

For prescribers considering this gel formulation, it offers a unique multi-modal approach may improve patient compliance and consequently, the overall treatment outcomes. However, the judicious selection of patients who can benefit from this formulation is important, particularly for conditions not traditionally associated with these ingredients. The use of this formulation for 'other uses', should be on a case-by-case basis, after careful consideration of known uses, patient's condition, safety profile, and efficacy of the ingredients.

If you have any questions or concerns about this product or its potential uses, we encourage you to reach out to us at Bayview Pharmacy. Our knowledgeable compounding pharmacists are here to guide you in considering this formulation for treatment.