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Clobetasol Propionate 0.0125%/Coal Tar 5%/Mometasone Furoate 0.12%/Salicylic Acid 5% Topical Cream

This formulation is a semisolid preparation of Clobetasol Propionate 0.0125%, Coal Tar 5%, Mometasone Furoate 0.12%, and Salicylic Acid 5% Topical Cream. It is dispensed in a pump mechanism for convenient and controlled application on the skin. The active ingredients in this formulation are designed for localized treatment and absorption.

The combination of Clobetasol Propionate and Mometasone Furoate, potent corticosteroids, provides anti-inflammatory, antipruritic, and vasoconstrictive actions. Coal Tar, a keratolytic agent, helps to slow down the rapid growth of skin cells and reduce inflammation. Salicylic Acid, another keratolytic, helps to shed dead skin cells and reduce scaling and thickness of the skin.

This formulation is used to treat various skin conditions such as psoriasis, eczema, and dermatitis. It helps to alleviate symptoms associated with these disease states, including itching, redness, and swelling.

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Topical Cream
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Formula Information

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This formulation is a topical cream that combines four active ingredients: Clobetasol Propionate 0.0125%, Coal Tar 5%, Mometasone Furoate 0.12%, and Salicylic Acid 5%. It is dispensed in a pump mechanism for easy and controlled application on the skin. This formulation is designed to treat a variety of skin conditions by delivering localized treatment directly to the affected area.

Clobetasol Propionate is a potent corticosteroid that works by reducing inflammation and suppressing an overactive immune response. This makes it effective in treating conditions such as eczema and psoriasis, where the body's immune system mistakenly attacks its own skin cells. Mometasone Furoate is another corticosteroid with similar properties, and its inclusion in the formulation provides an additional anti-inflammatory effect.

Coal Tar is a substance derived from coal that has been used for centuries to treat various skin conditions. It works by slowing the rapid growth of skin cells, which is a common feature of conditions like psoriasis. This helps to reduce the scaling and thickening of the skin that these conditions cause. Salicylic Acid is a keratolytic agent, which means it helps to soften and shed the outer layer of skin. This can help to reduce scaling and improve the appearance of the skin. It also has mild anti-inflammatory properties, which can help to reduce redness and swelling.

Together, these four ingredients provide a comprehensive approach to treating skin conditions. The corticosteroids reduce inflammation and suppress the immune response, the Coal Tar slows the growth of skin cells, and the Salicylic Acid helps to shed the outer layer of skin. This can help to reduce symptoms and improve the appearance of the skin. However, as with all medications, this formulation should be used as directed by a healthcare provider, and patients should report any side effects or worsening of symptoms to their provider immediately.

If you have any questions about this formulation, or if you would like more information about how it can be used to treat specific skin conditions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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This formulation contains four active ingredients: Clobetasol Propionate, Coal Tar, Mometasone Furoate, and Salicylic Acid. Each of these ingredients has its own potential for drug interactions, which should be considered when prescribing or using this medication.

Clobetasol Propionate is a potent corticosteroid that can interact with other corticosteroids, leading to an increased risk of systemic side effects such as adrenal suppression. It can also interact with drugs that affect the immune system, such as cyclosporine, tacrolimus, or biologics, potentially leading to increased risk of infections or other immune-related side effects. Patients should inform their healthcare provider if they are taking any of these medications.

Coal Tar may interact with certain drugs that increase sensitivity to sunlight, such as tetracycline antibiotics or certain diuretics, leading to an increased risk of sunburn. It can also interact with other topical medications, potentially leading to increased skin irritation. Patients should avoid using other topical products on the same area of skin where this medication is applied, unless directed by a healthcare provider.

Mometasone Furoate, another potent corticosteroid, has similar potential interactions as Clobetasol Propionate. It can interact with other corticosteroids and drugs that affect the immune system. Additionally, it can interact with certain drugs that are metabolized by the liver enzyme CYP3A4, such as ketoconazole, leading to increased levels of these drugs in the body. Patients should inform their healthcare provider if they are taking any medications that are metabolized by CYP3A4.

Salicylic Acid can interact with other drugs that affect blood clotting, such as aspirin or warfarin, potentially leading to increased risk of bleeding. It can also interact with other topical medications, potentially leading to increased skin irritation. Patients should avoid using other topical products on the same area of skin where this medication is applied, unless directed by a healthcare provider.

This formulation is designed to treat various skin conditions, such as psoriasis, eczema, and dermatitis. The combination of active ingredients works to reduce inflammation, slow the growth of skin cells, and remove scales, providing relief from symptoms. However, due to the potential for drug interactions, it is important for patients and prescribers to consider all other medications being used before starting this treatment. If you have any questions about this formulation or its potential interactions, please reach out to us at Bayview Pharmacy.

How Does it Work

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This formulation combines four active ingredients: Clobetasol Propionate, Coal Tar, Mometasone Furoate, and Salicylic Acid, each with a unique mechanism of action to treat various skin conditions. The cream is dispensed in a pump mechanism, which allows for easy and controlled application on the skin.

Clobetasol Propionate is a potent corticosteroid that works by reducing inflammation, itching, and redness. It does this by suppressing the immune response, which reduces the release of chemicals in the body that cause inflammation. This makes it particularly effective in treating conditions such as eczema and psoriasis.

Coal Tar is a byproduct of coal processing that has been used for centuries to treat various skin conditions. It works by slowing the rapid growth of skin cells, reducing the thickness of the skin and relieving symptoms. This makes it particularly effective in treating conditions such as psoriasis and dermatitis.

Mometasone Furoate is another potent corticosteroid that works similarly to Clobetasol Propionate. It reduces inflammation, itching, and redness by suppressing the immune response. This makes it particularly effective in treating conditions such as eczema, psoriasis, and dermatitis.

Salicylic Acid is a keratolytic (peeling agent) that causes shedding of the outer layer of skin. It works by softening and loosening the dry, scaly skin, making it easier to remove. This makes it particularly effective in treating conditions such as psoriasis, dandruff, and seborrheic dermatitis.

The combination of these four active ingredients in a single formulation provides a comprehensive approach to treating various skin conditions. The cream is designed for localized treatment, meaning it should be applied directly to the affected area of the skin. The pump mechanism allows for convenient and controlled application, ensuring that the right amount of cream is applied each time.

As with any medication, it's important to use this formulation as directed by your healthcare provider. If you have any questions about how to use this formulation, or if you're experiencing any side effects, don't hesitate to reach out to us at Bayview Pharmacy. We're here to help.

Other Uses

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While primarily used for managing inflammatory skin conditions such as psoriasis and dermatitis, the topically applied cream formulation of Clobetasol Propionate 0.0125%/Coal Tar 5%/Mometasone Furoate 0.12%/Salicylic Acid 5% can have other uses. One such additional usage is in the management of seborrheic dermatitis, a chronic inflammatory skin condition commonly observed in areas rich in sebaceous glands. Mometasone furoate, a potent topical steroid, and clobetasol propionate can reduce inflammation and redness, while coal tar and salicylic acid help in reducing flaking and scale build-up.

The components of this formulation can be effective in other skin disorders that have hyperkeratosis as a significant feature, such as lichen planus, where salicylic acid's keratolytic property can prove to be of benefit. Moreover, it is noted that coal tar has photoprotective properties, and this formulation could potentially be used in treating polymorphous light eruption or sunburn. Non-medical uses of this formulation could include the treatment of rough skin, calluses or corns, thanks to the salicylic acid component, although the potent corticosteroids included might limit use without a prescription.

A possible therapeutic potential for the formulation in some manifestations of lupus erythematosus may be worth exploring owing to the anti-inflammatory properties of mometasone and clobetasol. However, the evidence for such application is limited, and any usage for such conditions should be strictly guided by a dermatologist. Although this formulation, with its strong corticosteroid components and keratolytic agent, may benefit in several skin conditions, utilizing this outside of its main indications should always be done judiciously under the supervision of a healthcare professional due to the risk of side effects such as skin thinning, irritation, and hypothalamic-pituitary-adrenal (HPA) axis suppression.

If you have any questions regarding these other potential use cases and would like to inquire about compounding this product, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always ready to assist to maximize patient treatment outcomes and personalized drug therapy.

Frequently Asked Questions

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What is this compounded formulation made of?

This formulation is composed of Clobetasol Propionate at 0.0125%, Coal Tar at 5%, Mometasone Furoate at 0.12%, and Salicylic Acid at 5%.

What form does this compounded formulation come in?

The medication comes in the form of a semisolid topical cream. It can be conveniently dispensed via a pump mechanism for accurate and controlled application.

How should I apply this compounded formulation?

This formulation is designed for topical application, meaning it should be applied directly to the skin. Use the pump mechanism to dispense a portion of the cream and apply to the affected area as directed by your healthcare professional.

What are the main benefits of the pump mechanism?

The pump is designed to provide a convenient and controlled application. This allows for precise dosages and minimizes the risk of applying too much or too little medication.

Can this cream be applied to any part of the body?

This cream is formulated for localized treatment, usually applied to specific areas of the skin needing treatment. Kindly consult with your healthcare provider for specific instructions.

Who should use this compounded formulation?

This medication should be used as prescribed by a healthcare provider. The active ingredients in this formulation can be effective in treating a variety of skin conditions.

How often should I apply this medication?

The frequency of application can vary depending on your specific condition and advice from your healthcare provider. Always follow the prescribed administration and dosing schedule.

Can I use this cream with other skincare products?

Before applying any other skincare products, it's recommended to discuss your usual regimen with your healthcare provider to avoid possible interactions or disruptions in treatment effectiveness.

Do I need to refrigerate this cream?

Specific storage instructions for this cream will be provided by the pharmacist or your healthcare provider. Improper storage can affect the efficacy of the medication.

What should I do in case of an adverse reaction?

If you experience an adverse reaction after applying the cream, such as severe itching, redness, or swelling, discontinue use and immediately consult your healthcare provider.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.