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Formulas

Clobetasol Propionate 0.0025%/Ibuprofen 6%/Indomethacin 6%/Lidocaine 4% Topical Ointment

This formulation is a semi-solid topical ointment containing Clobetasol Propionate 0.0025%, Ibuprofen 6%, Indomethacin 6%, and Lidocaine 4%. It is dispensed in a tube and is designed for external application to the skin. The greasy or oily base of the ointment aids in the delivery of the medication, providing localized treatment.

The Clobetasol Propionate component is a potent corticosteroid that helps to reduce inflammation and itching. Ibuprofen and Indomethacin are nonsteroidal anti-inflammatory drugs (NSAIDs) that work by reducing the production of prostaglandins, substances in the body that cause inflammation. Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes.

This formulation is typically used for conditions such as skin inflammation, infections, or wound healing. It provides relief from pain, swelling, and discomfort associated with these conditions, while promoting healing and recovery.

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Clobetasol Propionate
Ibuprofen
Indomethacin
Lidocaine Hydrochloride
Topical Ointment
653fb3a30b06e70ca443338d
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Formula Information

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This formulation is a combination of Clobetasol Propionate, Ibuprofen, Indomethacin, and Lidocaine, each serving a unique therapeutic purpose. Clobetasol Propionate is a potent corticosteroid that works by reducing inflammation and immune responses. It is commonly used to treat a variety of skin conditions such as eczema, psoriasis, and dermatitis. The inclusion of this ingredient in the formulation helps to alleviate the symptoms of these conditions, including itching, redness, and swelling.

Ibuprofen and Indomethacin are nonsteroidal anti-inflammatory drugs (NSAIDs) that work by blocking the production of certain natural substances in your body that cause inflammation. These ingredients help to reduce pain, swelling, and joint stiffness caused by arthritis, bursitis, and gout attacks. When applied topically, they can provide localized relief from pain and inflammation.

Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It is used on the skin to stop itching and pain from certain skin conditions (e.g., scrapes, minor burns, eczema, insect bites) and to treat minor discomfort and itching caused by hemorrhoids and certain other problems of the genital/anal area (e.g., anal fissures, itching around the vagina/rectum).

This formulation is dispensed in a semi-solid form, designed for external application to the skin. The greasy or oily base aids in the delivery of the medication, ensuring that the active ingredients are absorbed effectively into the skin for localized treatment. This makes it an ideal choice for treating conditions such as skin inflammation, infections, or wound healing.

It is important for patients and prescribers to understand that while this formulation can provide significant relief from symptoms, it is not a cure for the underlying conditions. It should be used as part of a comprehensive treatment plan, under the supervision of a healthcare professional. As with any medication, it is important to use this formulation as directed, and to be aware of potential side effects, which may include skin irritation, burning, or redness at the application site. If these occur, contact your healthcare provider.

If you have any questions about this formulation, or if you would like more information about how it can be used in your specific situation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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This formulation contains four active ingredients: Clobetasol Propionate, Ibuprofen, Indomethacin, and Lidocaine. Each of these medications can interact with other drugs, potentially altering their effects or increasing the risk of adverse reactions. Therefore, it's crucial to inform your healthcare provider about all the medications you're currently taking, including prescription drugs, over-the-counter products, and herbal supplements.

Clobetasol Propionate is a potent corticosteroid that can interact with other topical corticosteroids, potentially leading to increased systemic absorption and the risk of Cushing's syndrome or adrenal suppression. If you're using other topical corticosteroids, discuss this with your healthcare provider to avoid potential interactions.

Ibuprofen and Indomethacin are nonsteroidal anti-inflammatory drugs (NSAIDs) that can interact with several other medications. For instance, they can increase the risk of bleeding when used with anticoagulants like warfarin or antiplatelet drugs like clopidogrel. They can also reduce the effectiveness of certain blood pressure medications and can increase the risk of kidney problems when used with other NSAIDs or diuretics. If you're taking any of these medications, inform your healthcare provider.

Lidocaine, a local anesthetic, can interact with other local anesthetics and certain antiarrhythmic drugs like amiodarone or mexiletine, potentially leading to additive systemic toxicity. If you're using other local anesthetics or taking any antiarrhythmic drugs, it's important to let your healthcare provider know.

This formulation is designed to treat various skin conditions. Clobetasol Propionate reduces inflammation and itching, making it useful for conditions like eczema and psoriasis. Ibuprofen and Indomethacin, being NSAIDs, provide pain relief and reduce inflammation, making them useful for conditions like arthritis or minor injuries. Lidocaine provides local anesthesia, numbing the skin to provide relief from pain or itching.

While this formulation is generally safe and effective, it's important to use it as directed by your healthcare provider. Overuse or misuse can lead to increased risk of side effects or drug interactions. If you have any questions or concerns about this formulation, don't hesitate to reach out to us at Bayview Pharmacy. We're here to help ensure that your treatment is safe and effective.

How Does it Work

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This formulation combines four active ingredients: Clobetasol Propionate, Ibuprofen, Indomethacin, and Lidocaine, each with a unique mechanism of action to provide comprehensive treatment for various skin conditions. The semi-solid formulation is designed to be applied topically, directly to the affected area, allowing for localized treatment and minimizing systemic side effects.

Clobetasol Propionate is a potent corticosteroid that works by reducing inflammation, itching, and redness. It does this by suppressing the immune response, thereby reducing the release of chemicals in the body that cause inflammation. This makes it particularly effective in treating conditions such as eczema and psoriasis.

Ibuprofen and Indomethacin are both non-steroidal anti-inflammatory drugs (NSAIDs) that work by inhibiting the production of prostaglandins, substances in the body that cause inflammation and pain. By reducing the levels of these substances, these NSAIDs help to alleviate pain and reduce inflammation. They are commonly used to treat conditions such as arthritis, bursitis, and gout.

Lidocaine is a local anesthetic that works by blocking nerve signals in your body. When applied topically, it causes a temporary loss of sensation in the area where it is applied, providing relief from pain and discomfort. This makes it useful in treating conditions that cause pain on the skin surface, such as minor burns, insect bites, or skin irritations.

The greasy or oily base of the ointment aids in the delivery of these medications, allowing them to penetrate the skin and reach the affected area. This formulation is typically used for conditions such as skin inflammation, infections, or wound healing. It provides a comprehensive approach to treatment, addressing not only the symptoms but also the underlying causes of inflammation and pain.

As compounding pharmacists, we are able to customize this formulation to meet the specific needs of each patient. We can adjust the concentrations of the active ingredients, change the base, or add other ingredients as needed. If you have any questions about this formulation, or if you would like to discuss how it could be customized to meet your needs, please reach out to us at Bayview Pharmacy. We are here to help.

Other Uses

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This unique blend of Clobetasol Propionate 0.0025%, Ibuprofen 6%, Indomethacin 6%, and Lidocaine 4% topical ointment is a versatile treatment option outside of its typical use for skin inflammation, infections, or facilitating wound healing.

Clobetasol Propionate is a potent corticosteroid that can also be applied to alleviate the bothersome symptoms of psoriasis and eczema. Inclusion of this effective ingredient enables the formulation to reduce skin inflammation and alleviate itching, redness, and swelling associated with these conditions.

The presence of Ibuprofen and Indomethacin, two powerful nonsteroidal anti-inflammatory drugs (NSAIDs), expands the palliative capabilities of this formulation beyond mere skin inflammation. Using this ointment might be effective in reducing localized pain stemming from common musculoskeletal conditions such as gout, arthritis, bursitis, or tendonitis. By inhibiting the production of prostaglandins, substances in the body that cause inflammation, these NSAIDs can lessen inflammation and related pain in the targeted area.

The addition of Lidocaine, a local anesthetic, to the formulation enables transient relief from discomfort caused by minor burns, sunburns, and insect bites. It functions by temporarily numbing the region of application, thus providing immediate symptomatic relief.

However, it's important to be aware that while this mixture could potentially provide relief for these additional conditions, its use should always be under the direction and consultation of a healthcare provider or pharmacist. This formulation has a unique blend of medications, each carrying their own risk of side effects and interactions. Patient's medical history, current medication regimen, and the nature and severity of symptoms should be thoroughly reviewed before initiating this treatment.

If you have any queries pertaining to this formulation or its uses, please reach out to us at Bayview Pharmacy. We boast a competent team of compounding pharmacists, experienced in providing precise answers to your health and medication related queries.

Frequently Asked Questions

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What is Clobetasol Propionate 0.0025%/Ibuprofen 6%/Indomethacin 6%/Lidocaine 4% Topical Ointment?

This is a semi-solid formulation that contains four active ingredients: Clobetasol Propionate 0.0025%, Ibuprofen 6%, Indomethacin 6%, and Lidocaine 4%. It is designed for topical application on the skin to manage and treat conditions such as skin inflammation, infections, or aid in wound healing.

How should the medicated ointment be stored?

This ointment should be stored at room temperature, away from heat and direct light. Avoid freezing and keep out of the reach of children.

What is the purpose of the combination of these four medications?

This combination of medications in one formulation aids in providing more comprehensive treatment. Clobetasol Propionate is a steroid that treats swelling, itching, and redness, Ibuprofen and Indomethacin are nonsteroidal anti-inflammatory drugs that also reduce inflammation, and Lidocaine is a local anesthetic that helps to decrease pain.

How is the ointment administered?

The ointment should be used only as directed by a healthcare professional. It is for external use on the skin only, and should be applied thinly and evenly over the affected area.

Can it be used for any kind of skin inflammation?

While it can help many kinds of skin inflammation, it should only be used when prescribed by a healthcare provider, as not all types of skin inflammation may be suitable for treatment with this ointment.

Is the medication safe to use on children?

The safety and effectiveness of this ointment in pediatric patients have not been established. Always consult a healthcare provider before using this medication on a child.

What happens if the medication is ingested orally?

This combination medication is intended for external use only. If it is accidentally ingested, immediately contact a healthcare provider or poison control center.

Can the ointment be used on open wounds?

This will depend on the specific instructions from your healthcare provider. Some types of wounds may benefit from the medication, while others may not. Always follow the advice of your healthcare provider.

What are the possible side effects of using this medicated ointment?

The potential side effects may include redness, itching, rash, swelling, or other signs of skin irritation. If these effects persist or worsen, contact your healthcare provider promptly.

How long should I use the ointment for?

You should use this ointment for the amount of time prescribed by your healthcare provider. Do not use this medication for a longer period without seeking medical advice, as prolonged use can cause major side effects.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.