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Formulas

Clioquinol 3%/Coal Tar 5%/Triamcinolone Acetonide 0.1% Topical Cream

This formulation is a semisolid preparation of Clioquinol 3%, Coal Tar 5%, and Triamcinolone Acetonide 0.1% Topical Cream. It is dispensed in a pump mechanism for convenient and controlled application on the skin. The active ingredients are designed for localized treatment and absorption.

The formulation is used to treat a variety of skin conditions. Clioquinol is an antifungal and antibacterial agent, effective in treating skin infections caused by fungi or bacteria. Coal Tar is a keratolytic, helping to shed dead skin cells from the top layer and slow down the growth of skin cells. This is beneficial in conditions such as psoriasis and dandruff. Triamcinolone Acetonide is a potent corticosteroid, providing relief from inflammatory skin conditions like eczema and dermatitis.

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Topical Cream
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Formula Information

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This formulation is a topical cream that combines Clioquinol, Coal Tar, and Triamcinolone Acetonide. It is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. This formulation is intended for localized treatment or absorption of active ingredients.

Clioquinol is an antifungal and antibacterial agent that works by inhibiting the essential enzymes in the pathogen, thereby preventing its growth and multiplication. It is effective in treating skin infections caused by fungi and certain bacteria. Coal Tar, on the other hand, is a keratolytic agent that works by causing the skin to shed dead cells from its top layer and slow down the growth of skin cells. This effect decreases scaling and dryness, helping to treat conditions such as psoriasis and dermatitis. Lastly, Triamcinolone Acetonide is a potent corticosteroid that reduces inflammation, itching, and redness. It is commonly used to treat a variety of skin conditions including eczema, allergies, and rash.

Together, these three active ingredients provide a comprehensive treatment approach for a variety of skin conditions. The antifungal and antibacterial properties of Clioquinol, the keratolytic action of Coal Tar, and the anti-inflammatory effects of Triamcinolone Acetonide work synergistically to alleviate symptoms and treat the underlying causes of skin disorders. This formulation is particularly beneficial for patients with complex skin conditions that require a multifaceted treatment approach.

It is important for patients and prescribers to understand that while this formulation can provide significant relief from symptoms, it is not a cure for the underlying conditions. Regular use as directed by a healthcare provider is necessary to maintain symptom control. Side effects may include skin irritation, burning, and dryness. If these side effects persist or worsen, contact your healthcare provider immediately.

If you have any questions about this formulation, its uses, or its potential side effects, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to help.

Drug Interactions

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The combination of Clioquinol, Coal Tar, and Triamcinolone Acetonide in a topical cream formulation is designed to treat a variety of skin conditions. Clioquinol is an antifungal and antibacterial agent, Coal Tar is a keratolytic agent that helps to shed dead skin cells, and Triamcinolone Acetonide is a corticosteroid that reduces inflammation and itching. This combination is particularly effective in treating conditions such as psoriasis, eczema, and dermatitis.

While this formulation is generally safe for most patients, there are potential drug interactions that prescribers and patients should be aware of. Clioquinol can interact with other topical medications that contain zinc, as it can form complexes with zinc that may reduce the effectiveness of both medications. Therefore, it is recommended to avoid concurrent use of Clioquinol with zinc-containing topical products.

Coal Tar can increase the skin's sensitivity to sunlight, which can lead to sunburn. Therefore, patients using this formulation should avoid excessive sun exposure and use sun protection when outdoors. Concurrent use of Coal Tar with other photosensitizing medications, such as certain antibiotics, diuretics, and cancer medications, can increase the risk of sunburn and should be avoided.

Triamcinolone Acetonide, being a corticosteroid, can interact with other corticosteroids, leading to an increased risk of side effects such as skin thinning, stretch marks, and acne. Therefore, concurrent use of this formulation with other corticosteroid-containing products should be avoided. Additionally, Triamcinolone Acetonide can interact with certain medications that suppress the immune system, such as cyclosporine and tacrolimus, potentially leading to increased risk of infections.

It's important to note that this is not a complete list of potential drug interactions. Patients should inform their healthcare provider of all the medications they are currently taking, including prescription drugs, over-the-counter medications, and dietary supplements. If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. We are a team of knowledgeable compounding pharmacists, and we are here to help.

How Does it Work

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This formulation combines three active ingredients: Clioquinol, Coal Tar, and Triamcinolone Acetonide, each with a unique mechanism of action to treat various skin conditions. The cream is designed to be applied topically, directly to the affected area, allowing for localized treatment and absorption of the active ingredients.

Clioquinol is an antifungal and antibacterial agent. It works by inhibiting the essential enzymes in the metabolic pathways of bacteria and fungi, thereby stopping their growth. This makes it effective in treating skin infections caused by fungi and certain bacteria.

Coal Tar, on the other hand, is a keratolytic agent. It works by causing the skin to shed dead cells from its top layer and slow down the growth of skin cells. This effect decreases scaling and dryness, helping to restore the skin's appearance. Coal Tar is commonly used in conditions such as psoriasis and eczema, where rapid skin cell turnover occurs.

Triamcinolone Acetonide is a potent corticosteroid. It works by reducing inflammation, itching, and redness by suppressing the immune response in the skin. This makes it effective in treating a variety of skin conditions characterized by inflammation and itching, such as dermatitis, allergies, and rash.

The cream is dispensed in a pump mechanism, which allows for convenient and controlled application. This ensures that the right amount of medication is applied each time, reducing the risk of side effects and improving the effectiveness of the treatment. The semisolid preparation also helps to keep the skin moisturized, which can aid in the healing process.

It's important to note that while this formulation can provide relief from symptoms, it may not cure the underlying condition. Therefore, it's crucial to use it in conjunction with other treatments as recommended by a healthcare provider. As with any medication, it's also essential to use this cream as directed to avoid potential side effects or complications.

If you have any questions about this formulation, how it works, or how to use it, don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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In addition to its primary indications, this formulation may have other potential uses due to its unique combination of active constituents. Clioquinol, a topical antifungal and antibacterial agent, may be applied to the skin to treat various types of fungal and bacterial skin infections beyond the primary indication. However, these potential uses should only be considered under the advice and supervision of a healthcare provider.

Moreover, Coal tar, a keratolytic agent, can soften and shed the top layer of skin, potentially useful in addressing other skin conditions characterized by hyperkeratinization or excessive skin scaling. This includes conditions like psoriasis, dandruff, and seborrheic dermatitis. Given its efficacy in alleviating itchiness, coal tar may also provide symptomatic relief for pruritus associated with these conditions.

Taking into account the triamcinolone acetonide, a potent corticosteroid, it can provide anti-inflammatory and immunosuppressive effects on various skin conditions. Triamcinolone is frequently used to treat an array of skin disorders such as eczema, dermatitis, allergies, and rash. It can reduce symptoms such as swelling, itching, and redness. So, it might be utilized in managing conditions like contact dermatitis, atopic dermatitis, nummular eczema, and lichen planus.

Despite these potential additional uses, it is critically important that the cream is applied under the direction of a healthcare provider and is never used on the face, groin, or underarms unless directed to do so by your doctor. Also, it should not be used on the skin areas that are broken, infected, or have open wounds. Patients must also be monitored for potential side effects or adverse reactions such as skin irritation, burning sensation, itching or dryness. Extended use, especially under occlusive dressings, may increase the risk of systemic side effects. If you are a healthcare provider or patient and have inquiries or need further information, don't hesitate to reach out to our team at Bayview Pharmacy.

Frequently Asked Questions

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What is this compounded formulation used for?

This compounded formulation of Clioquinol 3%/Coal Tar 5%/Triamcinolone Acetonide 0.1% Topical Cream is primarily used for the localized treatment of various skin conditions. The specific ingredients work in synergy to combat skin inflammation, itchiness, and bacterial or fungal infections.

How do I use this topical cream?

This cream comes in a pump mechanism for easy application. Apply a small amount of the cream to the affected area as directed by your healthcare provider. Rub it gently and thoroughly until it is absorbed into the skin. Keep in mind that it's designed for external use only.

How often should I apply the cream?

The frequency of application will depend on your specific condition and the advice of your healthcare provider. Always follow the instructions provided for best results.

Can I cover the area after application?

Do not cover the treated area unless directed by your healthcare provider. Covering the area can potentially increase absorption of the medication, possibly leading to unwanted side effects.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is near the time for your next dose, skip the missed dose and resume your normal dosing schedule. Do not double the dose to catch up.

What are potential side effects of this compound?

Potential side effects may include skin irritation, redness, dryness, or itching at the site of application. If any of these effects persist or worsen, promptly notify your healthcare provider.

What should I avoid while using this cream?

Avoid exposure to sunlight and tanning beds, as the ingredients in this formulation can make your skin more sensitive to light. Also, avoid interactions with other topical products unless instructed by your healthcare provider.

Can I use this cream with other skin products?

Before using this cream along with other skin products, consult your healthcare provider. Not all skin products may be compatible, and using multiple products could increase your risk of skin irritation or other side effects.

Is this topical cream safe for pregnant or nursing women?

If you are pregnant or nursing, consult your healthcare provider before using this product. While it's generally considered safe for topical use, it's important to discuss with your healthcare provider in order to evaluate any potential risks to you or your baby.

What should I do if the cream accidentally gets into my eyes or mouth?

If the cream accidentally enters your eyes or mouth, immediately rinse with plenty of water and seek medical attention if the discomfort continues. This cream is designed for external use only and should be kept out of reach of children to prevent accidental ingestion or application.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.