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Formulas

Clindamycin Phosphate 1.19% Topical Gel

Clindamycin Phosphate 1.19% Topical Gel is a semisolid formulation dispensed through a pump mechanism. This design allows for easy and precise application on the skin, ensuring targeted treatment or absorption of the active ingredient. The gel-like consistency of the formulation enhances the user experience and promotes better absorption.

This formulation is primarily used to treat various skin conditions. Clindamycin Phosphate is an antibiotic that works by stopping the growth of bacteria. It is effective in treating acne, reducing the number of acne lesions, and preventing new ones from forming. It is also used to treat bacterial infections of the skin, such as folliculitis and impetigo, and can be used in the treatment of certain types of skin abscesses.

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Topical Gel
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Formula Information

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Clindamycin Phosphate 1.19% Topical Gel is a semisolid formulation that is dispensed through a pump mechanism. This design allows for easy and precise application on the skin, ensuring that the active ingredients are targeted to the area of concern. The gel-like consistency of the formulation aids in the absorption of the active ingredients, providing effective treatment for various skin conditions.

Clindamycin Phosphate is an antibiotic that works by stopping the growth of bacteria. This antibiotic is used to treat a wide variety of bacterial infections, including those that cause acne. It can also be used to treat other skin and soft tissue infections. The 1.19% concentration in this formulation is designed to provide effective treatment while minimizing potential side effects.

When applied topically, Clindamycin Phosphate works by penetrating the skin and killing the bacteria that cause acne. It also has anti-inflammatory effects that can help to reduce redness and swelling associated with acne. This makes it a valuable treatment option for individuals suffering from this common skin condition.

For prescribers, it's important to note that while Clindamycin Phosphate is effective in treating a variety of bacterial infections, it should not be used in patients with a history of hypersensitivity to clindamycin or lincomycin. Additionally, it should be used with caution in patients with a history of gastrointestinal disease, particularly colitis, since it can cause severe colitis.

For patients, it's important to apply the gel as directed by your healthcare provider, typically once or twice daily. The gel should be applied to the entire affected area, not just the individual pimples. It's also crucial to continue using the medication for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection.

If you have any questions about Clindamycin Phosphate 1.19% Topical Gel, please don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to provide you with the information you need to make informed decisions about your healthcare.

Drug Interactions

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Clindamycin Phosphate 1.19% Topical Gel is a semisolid formulation that is dispensed through a pump mechanism, facilitating easy and precise application on the skin for targeted treatment or absorption of active ingredients in a gel-like consistency. This formulation is primarily used to treat bacterial infections of the skin, such as acne vulgaris, due to its antibiotic properties.

While Clindamycin Phosphate 1.19% Topical Gel is generally safe for use, it is important to be aware of potential drug interactions. Clindamycin is known to interact with certain other medications, which can affect how the drug works or increase the risk of side effects. For instance, it may interact with erythromycin, another antibiotic, which can lead to decreased effectiveness of both drugs. Therefore, it is not recommended to use these two medications together.

Additionally, Clindamycin may interact with neuromuscular blocking agents, which are drugs used during surgical procedures to relax the muscles. This interaction can enhance the effect of the neuromuscular blocking agent, potentially leading to prolonged muscle relaxation or paralysis. If you are scheduled for surgery, inform your doctor if you are using Clindamycin Phosphate 1.19% Topical Gel.

It's also important to note that while Clindamycin is a topical medication, it can be absorbed into the bloodstream, especially if used over large areas of skin or for prolonged periods. This means it could potentially interact with systemic medications. Therefore, it's crucial to inform your healthcare provider of all the medications you are currently taking, including over-the-counter drugs, vitamins, and herbal supplements.

Furthermore, Clindamycin Phosphate 1.19% Topical Gel should not be used in individuals who have a history of hypersensitivity to clindamycin or lincomycin, as this can lead to severe allergic reactions. Symptoms of an allergic reaction may include rash, itching, swelling, severe dizziness, or trouble breathing. If you experience any of these symptoms, seek medical attention immediately.

Lastly, while Clindamycin Phosphate 1.19% Topical Gel is used to treat bacterial infections, it should not be used for viral or fungal skin infections, as it will not be effective and may even worsen the condition.

If you have any questions about Clindamycin Phosphate 1.19% Topical Gel, its uses, or potential drug interactions, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

How Does it Work

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Clindamycin Phosphate 1.19% Topical Gel is a semisolid formulation that is dispensed through a pump mechanism. This design allows for easy and precise application on the skin, ensuring targeted treatment or absorption of the active ingredients in a gel-like consistency. The primary active ingredient in this formulation is Clindamycin Phosphate, which is a lincosamide antibiotic that works by inhibiting the synthesis of essential proteins required by bacteria to carry out vital functions.

Upon application, Clindamycin Phosphate penetrates the skin and is absorbed into the bacterial cells where it binds to the 50S subunit of the bacterial ribosome. This binding inhibits the early stage of protein synthesis, thereby preventing the bacteria from growing and multiplying. As a result, the bacterial population is reduced, leading to the resolution of infections.

This formulation is particularly effective in treating acne vulgaris, a common skin condition characterized by the presence of blackheads, whiteheads, and other types of pimples. The antibacterial properties of Clindamycin Phosphate help in reducing the amount of acne-causing bacteria on the skin, while its anti-inflammatory properties help in reducing the swelling and redness associated with acne.

Clindamycin Phosphate 1.19% Topical Gel can also be used in the treatment of other bacterial skin infections, such as folliculitis and impetigo. By reducing the bacterial population, this formulation aids in the healing of the infected skin and prevents the spread of the infection to other areas of the skin.

It's important to note that while Clindamycin Phosphate 1.19% Topical Gel is effective in treating bacterial skin infections, it may not be suitable for everyone. Some individuals may experience side effects such as dryness, burning, itching, or redness at the application site. In rare cases, more serious side effects may occur. Therefore, it's crucial to use this medication under the supervision of a healthcare provider.

If you have any questions about Clindamycin Phosphate 1.19% Topical Gel, its uses, or its potential side effects, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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Clindamycin Phosphate 1.19% Topical Gel is traditionally used as an antibacterial treatment for acne vulgaris, due to the drug's ability to reduce the concentration of free fatty acids on the skin surface, suppress the growth of Propionibacterium acnes (P. acnes, an anaerobic bacterium implicated in acne vulgaris pathogenesis) and decrease the inflammatory response.

However, this semisolid formulation can also be used for other applications. For instance, it might be used for Folliculitis and Furunculosis, skin conditions caused due to infected hair follicles. Clindamycin has shown strong efficacy in treating these conditions with its ability to inhibit protein synthesis of bacteria and lower inflammation.

Moreover, Clindamycin Phosphate Topical Gel has been employed in the management of bacterial skin infections, primarily Staphylococcus and Streptococcus skin infections. It also has a place in the treatment of Miliaria, a condition characterized by small, itchy rashes, also known as sweat rash.

Other off-label uses of this formulation can potentially entail the treatment of skin ulcers, burns, and wounds, where the application of topical antibiotics like Clindamycin can prevent or treat infections, and promote healing. Having said that, it's critical for such off-label uses to be always guided by a healthcare professional.

Please note that the effectiveness in these diverse applications depends on the individual patient's condition, their medical history, the presence of other infections, and their response to treatment. This makes it all the more essential to consult a prescriber or a healthcare professional before using Clindamycin for these applications.

In conclusion, apart from its usual role in treating acne, Clindamycin Phosphate 1.19% Topical Gel has the potential for wider dermatological use in treating infections, inflammations, and promoting wound healing. It's a testament to the versatility of our customized compounding formulations at Bayview Pharmacy.

If you have further questions and want to learn more about this formulation, or its potential for use in treating other skin conditions, feel free to reach out to our team. As compounding pharmacists, we pride ourselves on our expertise and our commitment to providing customized solutions to meet our patients’ unique health needs.

Frequently Asked Questions

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What is Clindamycin Phosphate 1.19% Topical Gel?

This is a semisolid formulation of Clindamycin Phosphate, an antibiotic. It is dispensed through a pump mechanism for easy and precise application on the skin. The active ingredients are delivered in a gel-like consistency for targeted treatment.

How does the Clindamycin Phosphate 1.19% Topical Gel work?

When applied topically, the antibiotic Clindamycin Phosphate works by inhibiting bacterial protein synthesis, ultimately treating the bacteria present on the skin and reducing swelling and redness.

How should I apply the topical gel?

It is dispensed through a pump mechanism to facilitate easy and precise application. It should be applied directly to the affected skin area. However, please follow your healthcare provider's specific instructions for use.

Can Clindamycin Phosphate 1.19% Topical Gel be used on all types of skin?

Yes, it can be used on all skin types. However, it should only be used as directed by your healthcare provider. Some individuals may have sensitivities to certain ingredients, so it's always best to try the product on a small area first.

What is the best way to store Clindamycin Phosphate 1.19% Topical Gel?

Store this medication at room temperature. Keep it away from heat, moisture, and direct light. Please do not freeze.

Is Clindamycin Phosphate 1.19% Topical Gel safe to use during pregnancy?

Discuss with your healthcare provider before using this medication while pregnant. While Clindamycin is generally considered safe to use during pregnancy, it is essential to discuss all medicines with your doctor during this period.

What should I do if I miss a dose of Clindamycin Phosphate 1.19% Topical Gel?

If you miss a dose, apply it as soon as possible. If it is almost time for your next dose, miss the missed dose and go back to your regular dosing schedule. Do not double doses.

Can I use Clindamycin Phosphate 1.19% Topical Gel for other skin conditions?

Clindamycin Phosphate 1.19% Topical Gel is mainly used for bacterial skin infections. However, your healthcare provider might recommend its use for other skin conditions. Always use the medication as recommended by your healthcare provider.

What are the side effects of Clindamycin Phosphate 1.19% Topical Gel?

Some common side effects include skin irritation where the gel is applied. If these continue or are bothersome, check with your healthcare provider. Serious side effects are rare but seek immediate medical attention if you notice any severe symptoms.

Can Clindamycin Phosphate 1.19% Topical Gel be used in combination with other topical medications?

Before using other topical medications, discuss with your healthcare provider as some products may interact with Clindamycin Phosphate 1.19% Topical Gel.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.