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Formulas

Clindamycin HCl 1%/Hydrocortisone 1%/Sulfacetamide Sodium 5% Topical Lotion

This formulation is a combination of Clindamycin HCl 1%, Hydrocortisone 1%, and Sulfacetamide Sodium 5% in a topical lotion form. It is a liquid or semi-liquid preparation intended for external application to the skin. The lotion provides a smooth and spreadable consistency, offering moisturizing, soothing, or therapeutic effects for specific skin conditions.

The active ingredients in this formulation are designed to be absorbed by the skin for localized treatment. Clindamycin HCl is an antibiotic that fights bacteria, Hydrocortisone is a corticosteroid that reduces inflammation, and Sulfacetamide Sodium is a sulfonamide antibiotic that inhibits the growth of bacteria.

This formulation is used to treat various skin conditions such as acne, rosacea, seborrheic dermatitis, and certain types of skin infections. It can also be used to manage inflammatory skin conditions and bacterial skin infections. The combination of these three active ingredients helps to reduce inflammation, fight bacterial infections, and soothe the skin.

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Topical Lotion
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Formula Information

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This formulation combines Clindamycin HCl 1%, Hydrocortisone 1%, and Sulfacetamide Sodium 5% in a topical lotion designed for external application to the skin. The lotion is either liquid or semi-liquid, providing a smooth and spreadable consistency that is easy to apply. It offers moisturizing and soothing effects, which can be beneficial for various skin conditions. More importantly, it promotes the absorption of the active ingredients, providing localized treatment to the affected area.

Clindamycin HCl is an antibiotic that works by stopping the growth of bacteria. It is used to treat a wide variety of bacterial infections, including those that cause acne. It helps to decrease the number of acne lesions. Hydrocortisone is a corticosteroid that works by reducing the swelling, redness, and itching that can occur with certain skin conditions. Sulfacetamide Sodium is a sulfonamide antibiotic that also works by stopping the growth of bacteria. It is used to treat certain skin conditions such as seborrheic dermatitis and certain types of rosacea. This combination of ingredients makes the lotion a versatile treatment for various skin conditions.

For patients, it's important to note that this medication is for use on the skin only. Clean and dry the affected area before applying the lotion. Also, avoid getting the medication in your eyes, nose, or mouth. If you do get the medication in those areas, flush with plenty of water. Use this medication regularly to get the most benefit from it. Remember to use it at the same time(s) each day.

For prescribers, it's crucial to inform patients about potential side effects, which may include mild burning, itching, or dryness of the skin. More serious side effects, such as skin thinning/discoloration, stretch marks, and hair bumps (folliculitis) may occur. If these effects persist or worsen, patients should be advised to stop using the medication and consult a healthcare professional. It's also important to note that this medication may interact with other topical medications, so a complete medication history should be obtained before prescribing.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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This formulation combines three active ingredients: Clindamycin HCl, Hydrocortisone, and Sulfacetamide Sodium. Clindamycin HCl is an antibiotic that works by stopping the growth of bacteria. Hydrocortisone is a corticosteroid that reduces redness, itching, and swelling. Sulfacetamide Sodium is a sulfonamide antibiotic that also works by stopping the growth of bacteria. This combination is typically used to treat certain types of skin infections and conditions, including acne, rosacea, seborrheic dermatitis, and certain types of skin inflammation.

While this formulation is generally safe for use, it's important to be aware of potential drug interactions. Clindamycin, when used topically, is not likely to interact with many drugs because it is not significantly absorbed into the bloodstream. However, it may interact with neuromuscular blocking agents, so caution should be exercised if you are taking these types of medications. Hydrocortisone, although also minimally absorbed, may interact with drugs such as aldesleukin, mifepristone, and certain drugs that weaken the immune system like natalizumab, rituximab. Sulfacetamide Sodium may interact with silver-containing products and certain types of cancer chemotherapy.

It's also important to note that this formulation should not be used with any products containing silver. Additionally, if you're taking any medications that can cause skin thinning (such as oral corticosteroids), let your healthcare provider know, as this may increase your risk of skin damage. Also, if you're using other topical medications, it's important to discuss this with your healthcare provider, as certain medications may interact with this formulation and cause skin irritation or other side effects.

As with any medication, it's important to use this formulation as directed by your healthcare provider. Avoid getting it in your eyes, nose, or mouth, and if you do, rinse with plenty of water. If your condition does not improve or if it worsens, contact your healthcare provider. Also, inform your healthcare provider if you experience any unusual or severe side effects, such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.

If you have any questions about this formulation or its potential interactions with other medications or products, please don't hesitate to reach out to us. We're here to help ensure that your treatment is safe and effective.

How Does it Work

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This formulation combines three active ingredients: Clindamycin HCl, Hydrocortisone, and Sulfacetamide Sodium, each with a unique mechanism of action to treat various skin conditions. Clindamycin HCl is an antibiotic that works by stopping the growth of bacteria. It is used to treat a wide variety of bacterial infections, including those that cause acne. This antibiotic treats only bacterial infections and will not work for virus infections. Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

Hydrocortisone, on the other hand, is a corticosteroid that works by reducing the swelling, redness, and itching that occurs in the skin infection. This medication is a mild corticosteroid. It is used to treat a variety of skin conditions such as eczema, dermatitis, allergies, and rash. Hydrocortisone reduces the swelling, itching, and redness that can occur in these types of conditions. This medication is a mild corticosteroid.

Sulfacetamide Sodium is a sulfa antibiotic. It works by stopping the growth of bacteria that cause certain skin infections. This antibiotic treats only bacterial skin infections. It will not work for other types of skin infections (e.g., infections caused by fungi, viruses). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

The lotion form of this medication is designed to be easily applied to the skin. It provides a smooth and spreadable consistency, which allows for even distribution of the medication across the affected area. The lotion also offers moisturizing effects, which can help soothe irritated skin and promote healing. The formulation is designed to promote absorption of the active ingredients into the skin for localized treatment of the skin condition.

It's important to use this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use topical clindamycin/hydrocortisone/sulfacetamide exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

If you have any questions about this medication or its use, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help you understand your medication and how to use it effectively.

Other Uses

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Given the unique combination of Clindamycin HCl, Hydrocortisone, and Sulfacetamide Sodium present in this formulation, it has been chiefly used to manage certain skin conditions like acne, dermatitis, and rosacea due to its antibiotic, anti-inflammatory, and sulfonamide properties. However, beyond these primary indications, there may be additional therapeutic applications worth considering.

The Clindamycin HCl component can assist in treating conditions beyond acne - it can help in managing topical infections caused by susceptible bacteria. Meanwhile, Hydrocortisone's anti-inflammatory, vasoconstrictive, and immunosuppressant effects can help manage the symptoms of various inflammatory diseases affecting the skin and mucous membranes. These include atopic dermatitis (eczema), pruritus, psoriasis, insect bites, and even allergic reactions presenting with skin manifestations.

Sulfacetamide Sodium is also a significant component in this formulation. It has been shown to compound the anti-inflammatory effects of hydrocortisone and possess some intrinsic antimicrobial activity. Thus, it may present additional benefits in the management of seborrheic dermatitis and other skin conditions associated with Malassezia yeast overgrowths.

Despite the potential other uses, it's crucial to note that the application of this formulation should be based upon physician recommendation and one should refrain from using it to self-treat other conditions without professional medical advice. Increased use or misuse can result in unwanted side effects such as skin irritation, redness, and peeling.

The concentration of the active ingredients in this formulation has been carefully selected to promote effectiveness while minimizing potential side effects. Still, each patient can react differently, and the dose might require adjustment for some. For any questions regarding the formulation or its potential uses, please do not hesitate to contact us at Bayview Pharmacy. Our team of compounding pharmacists is more than capable of answering your queries and providing assistance in understanding whether this formulation is suited to your specific needs.

Frequently Asked Questions

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What is the purpose of this compounded formulation?

This compounded formulation of Clindamycin HCl 1%/Hydrocortisone 1%/Sulfacetamide Sodium 5% Topical Lotion is designed to treat specific skin conditions. It is formulated to promote the absorption of active ingredients for localized treatment.

How should I apply this topical lotion?

It should be applied externally to the skin. Using your fingertips, apply a thin layer on the affected area and gently rub in until the lotion is fully absorbed.

What should I expect from the application of this topical lotion?

Because it is a liquid or semi-liquid formulation, you can expect a smooth and spreadable consistency. It provides moisturizing, soothing, or therapeutic effects to the area of the skin it is applied.

What are the active ingredients in this lotion?

The active ingredients in this topical lotion are Clindamycin HCl 1%, Hydrocortisone 1%, and Sulfacetamide Sodium 5%.

Are there any side effects to using this topical lotion?

As with all medicines, this lotion can cause side effects, although not everybody gets them. Common side effects may include itching, burning, or rash at the application site. If you notice any severe effects, please contact your healthcare provider immediately.

What should I do if I forget to apply the lotion?

Apply the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.

How should I store this lotion?

Store this lotion in a cool, dry place, away from heat and direct light. Do not freeze. Keep it out of the reach of children and pets.

Can this topical lotion be used with other medications?

Before starting any new medicine, please inform your healthcare provider. Some medications may interact with the active components in this lotion.

Can I use this lotion if I am pregnant or breastfeeding?

It is essential to consult your healthcare provider if you are pregnant, plan to get pregnant, or are breastfeeding before using this topical lotion.

Can I apply this lotion to broken or damaged skin?

No, the lotion should not be applied to broken or damaged skin. If you accidentally apply the lotion to these areas, rinse well with water.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.