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Formulas

Clindamycin 2%/Hydrocortisone 1%/Salicylic Acid 3% Topical Cream

This formulation is a compounded topical cream containing Clindamycin 2%, Hydrocortisone 1%, and Salicylic Acid 3%. It is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients.

Clindamycin is an antibiotic that fights bacteria, Hydrocortisone is a corticosteroid that reduces inflammation, and Salicylic Acid is a keratolytic (peeling agent) that causes shedding of the outer layer of skin. Together, these ingredients work to treat a variety of skin conditions.

This formulation is commonly used to treat acne, seborrheic dermatitis, and psoriasis. It can also be used to manage other skin conditions as directed by a healthcare provider. The combination of these active ingredients helps to reduce inflammation, fight bacterial infections, and promote the shedding of dead skin cells, thereby improving the appearance and health of the skin.

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Topical Cream
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Formula Information

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This formulation is a combination of Clindamycin 2%, Hydrocortisone 1%, and Salicylic Acid 3% in a topical cream. Clindamycin is an antibiotic that works by stopping the growth of bacteria. It is used to treat a wide variety of bacterial infections. Hydrocortisone is a corticosteroid that reduces redness, itching, and swelling. Salicylic Acid is a keratolytic (peeling agent) that causes shedding of the outer layer of skin. It is used to treat conditions such as acne, dandruff, psoriasis, and seborrheic dermatitis of the skin and scalp.

The cream is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. This allows for localized treatment or absorption of the active ingredients. The cream is applied to the affected area, usually once or twice daily, or as directed by your doctor. The dosage and length of treatment are based on your medical condition and response to treatment.

Before using this medication, clean the affected area and dry well. Apply a thin layer of the medication to the affected area and gently rub in, usually 2 to 4 times daily or as directed by your doctor. Wash your hands after using, unless you are using this medication to treat the hands. Do not apply this medication in the eyes, nose, mouth, or any areas of broken skin unless directed to do so by your doctor. Wait until the effects of such products on the skin have decreased before using this medication.

It is important to note that this medication may cause temporary stinging and irritation when first applied to the skin. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

For any questions or concerns regarding this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always ready to assist you.

Drug Interactions

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This formulation combines the antibiotic properties of Clindamycin, the anti-inflammatory effects of Hydrocortisone, and the keratolytic action of Salicylic Acid. Clindamycin is a lincosamide antibiotic that works by inhibiting bacterial protein synthesis, making it effective against a variety of bacterial infections. Hydrocortisone is a corticosteroid that reduces inflammation, itching, and redness. Salicylic Acid is a beta hydroxy acid that works by causing the cells of the epidermis to shed more readily, opening clogged pores and neutralizing bacteria within.

When using this formulation, it's important to be aware of potential drug interactions. Clindamycin can interact with other antibiotics, specifically macrolides and chloramphenicol, which can inhibit its antibacterial effect. It can also interact with neuromuscular blocking agents, potentially enhancing their action. Hydrocortisone, being a corticosteroid, can interact with drugs like insulin, warfarin, and cyclosporine, potentially requiring adjustments in their dosages. Salicylic Acid can increase the absorption of topical medications, so caution should be exercised when used with other topical treatments.

Patients should be advised to inform their healthcare provider of all the medications they are currently taking, including over-the-counter drugs, dietary supplements, and herbal products. This is to ensure that any potential interactions can be identified and managed appropriately. It's also important to note that while this formulation is designed for topical use, systemic absorption can still occur, especially when applied over large areas or under occlusive dressings. This can potentially lead to systemic side effects, especially with prolonged use.

This formulation is primarily used in the treatment of skin conditions such as acne, dermatitis, and psoriasis. Clindamycin targets the bacteria involved in acne, while Hydrocortisone reduces the inflammation and redness associated with these conditions. Salicylic Acid helps to unclog pores and shed the outer layer of skin, which can be beneficial in conditions like psoriasis where there is an overproduction of skin cells.

As with any medication, this formulation should be used as directed by a healthcare provider. Patients should be advised to apply the cream to the affected area in the amount and frequency prescribed. They should also be instructed to avoid contact with the eyes, mouth, and other mucous membranes. If any adverse reactions occur, such as severe irritation, redness, or swelling, patients should be advised to discontinue use and contact their healthcare provider immediately.

If you have any questions about this formulation or its use, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

How Does it Work

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This formulation combines three active ingredients: Clindamycin, Hydrocortisone, and Salicylic Acid, each with a unique mechanism of action to treat various skin conditions. The cream is designed to be applied topically, directly to the affected area of the skin, allowing for localized treatment and absorption of the active ingredients.

Clindamycin is an antibiotic that works by stopping the growth of bacteria. It is effective against a wide range of organisms, including the bacteria associated with acne, Propionibacterium acnes. By reducing the number of bacteria on the skin, Clindamycin helps to reduce inflammation and the formation of acne.

Hydrocortisone is a corticosteroid that works by reducing inflammation and immune responses. It helps to relieve symptoms such as swelling, itching, and redness. This makes it useful in treating a variety of skin conditions, including eczema, dermatitis, allergies, and rash. Hydrocortisone works by suppressing the body's immune response, thereby reducing inflammation and discomfort.

Salicylic Acid is a keratolytic (peeling agent). It causes the cells of the epidermis to shed more readily, opening clogged pores and neutralizing bacteria within. It also prevents pores from clogging up again by constricting pore diameter, and allowing room for new cell growth. Because of its effect on skin cells, Salicylic Acid is used to treat skin conditions that involve scaling or overgrowth of skin cells such as psoriasis, dandruff, corns, callus, and warts.

Together, these three ingredients work synergistically to treat a variety of skin conditions. The antibiotic properties of Clindamycin, the anti-inflammatory effects of Hydrocortisone, and the keratolytic action of Salicylic Acid combine to provide a comprehensive treatment approach. This formulation is dispensed in a pump mechanism, which allows for convenient and controlled application of the cream to the skin.

As with any medication, it's important to use this cream as directed by your healthcare provider. If you have any questions about this formulation or how to use it, don't hesitate to reach out to us at Bayview Pharmacy. We're here to help ensure you get the most benefit from your medications.

Other Uses

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This tri-component formulation of Clindamycin, Hydrocortisone, and Salicylic Acid is commonly prescribed as a topical therapy for various skin conditions such as acne, inflammation, psoriasis and dermatitis due to its combined antibacterial, anti-inflammatory, and keratolytic effects. However, it could also be useful for other skin-related conditions.

The Clindamycin in this formula is a potent lincosamide antibiotic that is particularly effective against Gram-positive bacteria, including varieties implicated in acne vulgaris. Therefore, it can also be employed in the treatment of folliculitis, impetigo, and other superficial skin infections caused by susceptible bacteria. On the other hand, Hydrocortisone is a topical corticosteroid that can help reduce itching, redness, and swelling associated with various skin conditions. In certain instances, it can be applied to insect bites, poison ivy rashes, eczema, or seborrheic dermatitis to provide relief.

Moreover, Salicylic Acid has keratolytic properties, meaning it promotes exfoliation of the skin by increasing moisture and dissolving the substance that causes skin cells to stick together. This makes it a helpful adjunct in the topical treatment of conditions like corns, calluses, dandruff, and warts. Its desquamation capacity can also be beneficial for patients with ichthyosis or keratosis pilaris.

Although, it is meant for skin application, it should always be used under proper medical guidance because overuse can lead to skin dryness, peeling, and irritation, and its components could potentially be absorbed systemically and cause side effects in certain patients, especially in those with large surface lesions or delicate skin. This formulation also needs to be avoided on broken skin or open wounds as well as near the eyes, nose, mouth, or genitals unless explicitly directed by the prescribing provider. Also, patient should be on the lookout for any signs of adverse drug reactions and report them to their healthcare provider promptly.

If you have any questions about this piece, please feel free to contact us at Bayview Pharmacy. We are a dedicated team of compounding pharmacists ready to assist you with any query regarding this compound or any other pharmaceutical matter.

Frequently Asked Questions

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What is the purpose of Clindamycin 2%/Hydrocortisone 1%/Salicylic Acid 3% Topical Cream?

This topical cream is designed to treat skin conditions by applying the cream directly to the affected area, so that the active ingredients can be absorbed through the skin for localized treatment. The ingredients work together to combat bacteria, reduce inflammation and irritation, and promote the shedding of dead skin cells.

What is the best way to apply Clindamycin 2%/Hydrocortisone 1%/Salicylic Acid 3% Topical Cream?

The cream comes in a pump mechanism which is designed for convenient and controlled application. Apply a thin layer of the cream onto the affected area of skin, spreading it evenly. This should be done according to the directions provided by your healthcare professional.

Can I use this topical cream all over my body?

This cream is primarily designed for localized treatment. It should be applied to the specific area of skin requiring treatment, rather than being used as a general moisturizer or lotion for large body areas.

What are the active ingredients in this cream?

The active ingredients in this cream are Clindamycin 2%, a powerful antibiotic that fights against bacteria; Hydrocortisone 1%, a corticosteroid that reduces itching, redness, and swelling; and Salicylic Acid 3%, a keratolytic agent that encourages the shedding of dead skin cells.

What side effects might I experience?

Some possible side effects include redness, peeling, or unusual dryness of the skin. More serious side effects may include increased skin sensitivity or allergic reactions. If you experience any serious side effects, contact your healthcare professional immediately.

When will I begin to see results?

Results vary between individuals, depending on the severity of the skin condition and individual responses to treatment. Typically, improvement may be seen within a few days to weeks, but complete resolution may take longer. Consult your healthcare provider for more precise timelines.

Can I use other skincare products with this cream?

Before using other skincare products in combination with this cream, it is recommended to consult your healthcare provider, as some products may alter the effectiveness of the cream or cause additional skin irritation.

Does the cream have a specific storage requirement?

Store the cream at room temperature and keep it out of reach of children. It should not be exposed to excessive heat or cold, and should not be stored in a humid environment, such as a bathroom.

What if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it is near the time of your next dose, skip the missed dose and continue with your regular dosing schedule to avoid overdosage.

Should I be aware of any drug interactions?

Some products may interact with this cream, altering its effectiveness or causing unwanted side effects. It is important to inform your healthcare provider of all the products you use, including prescription drugs, nonprescription drugs, and herbal products, before starting treatment.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.