Sublingual Semaglutide (generic Ozempic®) now available! Get Started
Dashboard
Formulas

Clindamycin 1%/Niacinamide 4%/Tretinoin 0.01% Topical Gel

This formulation is a combination of Clindamycin 1%, Niacinamide 4%, and Tretinoin 0.01% in a topical gel form. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

Clindamycin is an antibiotic that prevents bacteria from growing on the skin. Niacinamide, also known as vitamin B3, has anti-inflammatory properties that can help ease redness from eczema, acne, and other inflammatory skin conditions. Tretinoin is a form of vitamin A that helps the skin renew itself more quickly.

This formulation is used to treat various disease states including acne, rosacea, and other inflammatory skin conditions. It can also be used to improve the appearance of the skin by reducing fine lines and wrinkles, improving skin texture, and reducing discoloration and brown spots caused by sun damage.

Want a different strength?
Click the Text Us button below.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Must be E-Prescribed
Get Started
Generate LeafletShow Leaflet
This medication requires a prescription from your doctor
Trusted by 60,357 patients to date.
A group of faces of our past satisfied patients.
A svg symbol of a mortar and pestle with ingredients going in.
Custom made in our compounding labs.
Sliders that show the customization of ingredients.
Personalized treatment for better results.
User with a gear showing the personalization of the formulation.
All strengths and ingredients are tailored to your needs.
This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.
Topical Gel
653ec80284f4004d4e1f3f12
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Dosing Calculator

Get general dosing information for a patient by using this calculator.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Formula Information

A small arrow pointing down

This formulation is a combination of Clindamycin 1%, Niacinamide 4%, and Tretinoin 0.01% in a topical gel form. Clindamycin is an antibiotic that works by stopping the growth of bacteria. It is used to treat a wide variety of bacterial skin infections. Niacinamide, also known as vitamin B3, has anti-inflammatory properties that can help ease redness from eczema, acne, and other inflammatory skin conditions. It also helps build keratin, a type of protein that keeps your skin firm and healthy. Tretinoin, a derivative of vitamin A, is commonly used to treat acne and reduce the appearance of fine lines and wrinkles. It works by affecting the growth of skin cells.

The gel is dispensed through a pump mechanism, which allows for easy and precise application on the skin. This ensures that the active ingredients are targeted to the area of concern, maximizing their effectiveness. The gel-like consistency allows for a smooth application and quick absorption into the skin, providing fast relief from symptoms.

This formulation is particularly effective in treating acne, a common skin condition that causes pimples, blackheads, and whiteheads. The Clindamycin component works by reducing the bacteria that cause acne, while the Tretinoin helps to decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Niacinamide helps to reduce inflammation and redness associated with acne, and also helps to improve the skin's texture and tone.

It is also effective in treating rosacea, a skin condition that causes redness and visible blood vessels in your face. Niacinamide can help reduce inflammation, redness, and swelling associated with rosacea. Tretinoin can help reduce the appearance of fine lines and wrinkles, improving the overall appearance of the skin.

For best results, this formulation should be used as directed by a healthcare provider. It is typically applied to the affected area once a day, in the evening or as directed by your doctor. The length of treatment will depend on the severity of the condition and the individual's response to treatment.

As with any medication, there may be potential side effects, including dryness, redness, or peeling of the skin. If these side effects persist or worsen, contact your healthcare provider immediately. It is also important to use sunscreen and wear protective clothing when outdoors, as this medication can make you more sensitive to the sun.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you with any concerns or queries you may have.

Drug Interactions

A small arrow pointing down

This formulation combines Clindamycin, Niacinamide, and Tretinoin, each with its own unique therapeutic properties. Clindamycin is an antibiotic that fights bacteria in the body, Niacinamide (Vitamin B3) has anti-inflammatory properties that may help ease redness from eczema, acne, and other inflammatory skin conditions, and Tretinoin is a form of vitamin A that helps the skin renew itself.

While this formulation is generally safe for use, it's important to be aware of potential drug interactions. Clindamycin, when used topically, has minimal systemic absorption and thus, systemic drug interactions are unlikely. However, it should be used with caution in patients who are concurrently taking neuromuscular blocking agents. Niacinamide is generally well-tolerated and has no known significant drug interactions. Tretinoin, on the other hand, may interact with drugs that increase the skin's sensitivity to sunlight, such as thiazide diuretics, sulfa drugs, quinolone antibiotics, and phenothiazines. Concurrent use of these medications may lead to increased risk of sunburn.

Furthermore, the use of other topical acne treatments (containing benzoyl peroxide, salicylic acid, or sulfur) with this formulation may lead to increased skin irritation. It's recommended to space the application of these treatments and this formulation to reduce the risk of skin irritation. Also, the use of products containing alcohol, astringents, lime, or spices may also result in skin irritation when used with this formulation.

This formulation is primarily used to treat acne and other inflammatory skin conditions. Clindamycin works by reducing the number of acne bacteria (Cutibacterium acnes) and by decreasing the inflammation caused by these bacteria. Niacinamide helps to reduce inflammation and improve the skin barrier function, which can be beneficial in inflammatory skin conditions like acne. Tretinoin promotes the turnover of skin cells, which helps to unclog pores and reduce the formation of acne lesions.

It's important to note that while this formulation can help manage these conditions, it may not be suitable for everyone. Patients with a history of hypersensitivity to any of the ingredients should not use this formulation. Also, pregnant or breastfeeding women should consult their healthcare provider before using this formulation as Tretinoin is known to cause birth defects.

If you have any questions about this formulation or its use, please don't hesitate to reach out to us. We're here to help ensure that you have all the information you need to use this formulation safely and effectively.

How Does it Work

A small arrow pointing down

This formulation combines three active ingredients: Clindamycin, Niacinamide, and Tretinoin, each with a unique mechanism of action to treat various skin conditions. Clindamycin is an antibiotic that works by stopping the growth of bacteria that cause acne. It helps to decrease the number of acne lesions. Clindamycin is only able to treat bacterial infections and will not work for virus infections.

Niacinamide, also known as vitamin B3, has anti-inflammatory properties that can help ease redness from eczema, acne, and other inflammatory skin conditions. It also helps build cells in the skin while also protecting them from environmental stresses, such as sunlight, pollution, and toxins. Niacinamide can also minimize pore appearance, keep skin smooth and moisturized, and reduce the impact of aging.

Tretinoin, a derivative of vitamin A, works by affecting the growth of skin cells. It is commonly used to treat acne and reduce the appearance of fine wrinkles and mottled skin discoloration, and to make rough facial skin feel smoother. Tretinoin promotes the peeling of affected skin areas and unclogs pores. This effect decreases the formation and severity of acne pimples and promotes quick healing of pimples that do develop.

The gel formulation allows for easy and precise application of these active ingredients directly to the affected skin areas. The semisolid consistency of the gel ensures that the active ingredients are kept in contact with the skin for a sufficient amount of time to allow for their absorption and action. The pump mechanism of the dispenser allows for controlled and hygienic dispensing of the product, reducing the risk of contamination.

It's important to note that while this formulation can significantly improve skin conditions, it may not completely clear up more severe cases. It's also crucial to use this medication as directed by a healthcare professional, as overuse or misuse can lead to skin irritation or decrease the effectiveness of the medication.

If you have any questions about this formulation, its use, or how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

A small arrow pointing down

Clindamycin 1%/Niacinamide 4%/Tretinoin 0.01% Topical Gel provides a multi-component approach to addressing numerous skin issues. Apart from treating the diseases specified, this formulation has potential utility in the treatment of variety of other skin conditions. Clindamycin, an antibiotic, can be helpful in managing mild to moderate bacterial infections on the skin. When combined with the therapeutic benefits of Niacinamide and Tretinoin, this can greatly assist in controlling inflammatory skin conditions like folliculitis and skin wounds inflicted by bacteria.

Additionally, Niacinamide, as an active form of Vitamin B3, is well-documented for its anti-inflammatory qualities making it a viable agent for treating inflammatory skin conditions such as rosacea and possibly psoriasis. It also contributes to improved skin barrier function, reducing the effects of environmental damage. The combination of Niacinamide and Tretinoin has been shown to improve pigmentation issues, so this formulation may be beneficial for patients with melasma or post-inflammatory hyperpigmentation.

Tretinoin, as a highly potent form of vitamin A, is a famous skincare ingredient that promotes skin rejuvenation and addresses issues like acne, sun damage, and signs of aging. Therefore, in this multi-component medication, Tretinoin may be beneficial in treating premature signs of skin aging, like wrinkles and fine lines, and other symptoms of photodamage. Additionally, its beneficial effects for treating severe forms of acne are well-documented, hence in case of resistant acne, this formulation can be a potential option.

It must be remembered, though, that the effects of any medication vary from person to person, and hence the appropriateness of this formulation and drug concentrations for any individual patient's condition should be re-evaluated by their dermatologist or healthcare provider. As a team of compounding pharmacists, we are more than happy to work with both patients and prescribers to provide tailored solutions for individual skincare needs. Should you have any questions or uncertainties, please don't hesitate to reach out to us at Bayview Pharmacy.

Frequently Asked Questions

A small arrow pointing down

What is Clindamycin 1%/Niacinamide 4%/Tretinoin 0.01% Topical Gel?

Clindamycin 1%/Niacinamide 4%/Tretinoin 0.01% Topical Gel is a compounded medication used as a targeted skin treatment. It involves a combination of three active ingredients (Clindamycin, Niacinamide, and Tretinoin) in a gel-like consistency to help address skin conditions.

How do I apply Clindamycin 1%/Niacinamide 4%/Tretinoin 0.01% Topical Gel?

This product is dispensed through a pump mechanism for easy and precise application. Simply apply the gel to the treatment area as prescribed by your physician, ensuring that it is properly absorbed by the skin.

What are the benefits of the pump mechanism?

The pump mechanism provides a controlled and targeted application of the gel. This facilitates efficiency and accuracy in administering the formulation specifically to the treatment area.

What is the function of Clindamycin in this formulation?

Clindamycin is an antibiotic which helps to stop the growth of bacteria. In the context of this topical formulation, it aids in treating bacterial infections of the skin.

What is the role of Niacinamide in this product?

Niacinamide, also known as vitamin B3, is believed to provide various benefits for the skin. These benefits may include reducing inflammation, brightening the complexion, and improving the skin barrier function.

Why does this formulation include Tretinoin?

Tretinoin is a type of retinoid, commonly used in skincare for its rejuvenating effects. It is known to promote cell turnover and can help treat acne and signs of ageing, such as wrinkles.

Can everyone use Clindamycin 1%/Niacinamide 4%/Tretinoin 0.01% Topical Gel?

As with all topical medications, responses can vary among users. This product should be used as directed by a healthcare professional, and is not recommended for individuals who are allergic to any of its components. If you have any health conditions or concerns, consult a healthcare provider before using the product.

What if I experience side effects while using this formulation?

If you experience any adverse events, it’s important to stop usage and consult with your doctor immediately. Reported side effects may include redness, dryness, peeling, or sensitivity where the product is applied.

Will this product cure my skin condition?

While Clindamycin 1%/Niacinamide 4%/Tretinoin 0.01% Topical Gel can assist in managing and improving various skin conditions, it is not promoted as a cure. The effectiveness of the product can vary among users and depends on the nature of the individual skin condition, as well as the consistency of use.

Do I need a prescription for Clindamycin 1%/Niacinamide 4%/Tretinoin 0.01% Topical Gel?

Yes, this formulation is a compounded medication intended for use under the supervision of a healthcare provider. It will require a prescription from a licensed practitioner.

Related Formulas

Related Products
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.