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Formulas

Cisapride 10 mg Oral Capsules (Vet)

Cisapride 10 mg Oral Capsules (Vet) are a solid dosage form, consisting of two gelatin or vegetarian shells that enclose the active ingredient, Cisapride. This formulation is designed for easy swallowing and ensures a precise dosage of 10 mg per capsule. Cisapride is commonly used in veterinary medicine to treat certain disease states, including gastrointestinal disorders such as gastroparesis and chronic idiopathic constipation. It works by enhancing the motility of the gastrointestinal tract, thereby aiding in the treatment of these conditions.

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Formula Information

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Cisapride 10 mg Oral Capsules (Vet) is a solid dosage form that is composed of two gelatin or vegetarian shells. These shells enclose the medication, allowing for convenient and easy swallowing. This formulation provides a precise dosage of the active ingredients, ensuring that the patient receives the exact amount of medication needed for effective treatment.

Cisapride is a prokinetic agent that works by increasing the release of acetylcholine, a neurotransmitter that stimulates the smooth muscle in the gastrointestinal tract. This action enhances gastric emptying and movement of the intestines, making it an effective treatment for certain gastrointestinal disorders. In veterinary medicine, Cisapride is commonly used to treat conditions such as gastroesophageal reflux disease (GERD), chronic constipation, and certain forms of megacolon in cats and dogs.

It's important to note that while Cisapride can be highly effective, it should be used with caution in pets with a history of heart disease, as it can potentially cause serious cardiac side effects. Additionally, it should not be used in animals with a known hypersensitivity to the drug. As with any medication, it's crucial to follow the prescribing veterinarian's instructions closely when administering Cisapride to your pet.

For prescribers, it's essential to be aware of the potential interactions Cisapride can have with other medications. For instance, it should not be used in conjunction with certain antifungal drugs, macrolide antibiotics, or other medications that can prolong the QT interval, as this can increase the risk of serious cardiac side effects. Regular monitoring of the patient's condition and any potential side effects is also recommended while the patient is on this medication.

If you have any questions about Cisapride 10 mg Oral Capsules (Vet), please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to provide the information and support you need.

Drug Interactions

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Cisapride is a medication that is primarily used in veterinary medicine to treat certain gastrointestinal conditions in animals, such as chronic constipation or gastroesophageal reflux disease (GERD). It works by increasing the movement of the stomach and intestines, helping to speed up the passage of food. However, it's important to be aware of potential drug interactions when using this medication.

One of the most significant interactions to be aware of is with medications that can cause QT prolongation, a serious heart condition. These include certain antipsychotics (like haloperidol), macrolide antibiotics (like erythromycin), and certain antiarrhythmic medications (like amiodarone). Combining these medications with cisapride can increase the risk of serious, potentially life-threatening heart rhythm abnormalities.

Other medications that can interact with cisapride include certain antifungal medications (like ketoconazole and itraconazole), certain antidepressants (like fluoxetine), and certain calcium channel blockers (like diltiazem). These medications can increase the levels of cisapride in the body, potentially leading to an increased risk of side effects.

It's also important to be aware that certain foods and drinks can interact with cisapride. For example, grapefruit juice can increase the levels of cisapride in the body, potentially leading to an increased risk of side effects. Therefore, it's generally recommended to avoid consuming grapefruit juice while taking this medication.

Given the potential for serious drug interactions, it's crucial to inform your veterinarian of all medications your pet is currently taking, including over-the-counter medications, herbal supplements, and any other substances that could potentially interact with cisapride. This will help ensure the safe and effective use of this medication.

If you have any questions about cisapride or its potential interactions, don't hesitate to reach out to us. Our team of compounding pharmacists at Bayview Pharmacy is always here to provide you with the information and support you need.

How Does it Work

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Cisapride 10 mg Oral Capsules (Vet) are a solid dosage form that consists of two gelatin or vegetarian shells enclosing the medication. This design allows for easy swallowing and ensures a precise dosage of the active ingredients. The primary active ingredient in this formulation is Cisapride, a prokinetic agent that works by enhancing the motility of the gastrointestinal tract.

Cisapride works by acting on the serotonin receptors in the gut, specifically the 5-HT4 receptors. When these receptors are stimulated, they trigger the release of acetylcholine, a neurotransmitter that promotes the contraction of the smooth muscles in the gastrointestinal tract. This action enhances gastric emptying and increases the tone of the lower esophageal sphincter, thereby improving the movement of food and fluids through the digestive system.

This formulation is particularly useful in treating a variety of gastrointestinal disorders in animals, such as chronic constipation, gastroesophageal reflux disease (GERD), and certain forms of dyspepsia. By improving the motility of the gastrointestinal tract, Cisapride helps to alleviate the symptoms associated with these conditions, such as bloating, heartburn, and discomfort. It can also help to prevent the formation of hairballs in cats by promoting the passage of ingested hair through the digestive system.

It's important to note that while Cisapride can be highly effective in treating these conditions, it should be used with caution in animals with known hypersensitivity to the drug, or in those with pre-existing heart conditions, as it can potentially cause serious cardiac side effects. As with any medication, it's crucial to follow the prescribing veterinarian's instructions closely when administering Cisapride to your pet.

If you have any questions about Cisapride 10 mg Oral Capsules (Vet) or any other medications, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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Cisapride 10 mg oral capsules are most commonly used in veterinary medicine to treat disorders related to gastric motility. However, this medication may also be useful in other challenging conditions. Increasingly, veterinarians are prescribing cisapride in management of chronic constipation and megacolon in cats. It is also used off-label for rabbits and other pets to stimulate proper digestion when they are affected by gastrointestinal stasis, a condition in which the normal propulsive ability of the pet's gastrointestinal tract is seriously compromised.

In horses, Cisapride is sometimes used to treat gastric ulcers and reflux disease due to its promotility effects on the gastrointestinal tract. Horses with chronic impaction colic may also be candidates for treatment with cisapride. However, prescribing cisapride for off-label uses in large animals should be done with caution and under the close supervision of an experienced veterinarian, as certain doses may be associated with potentially adverse cardiac effects.

While cisapride has been traditionally used in human medicine to treat gastro-esophageal reflux disease (GERD), its use has been largely discontinued due to its potential to cause serious cardiovascular side effects. The benefit-to-risk balance of cisapride usage is currently considered more favorable in veterinary medicine, provided appropriate caution and patient monitoring are observed.

It's essential to remember that any off-label usage of cisapride or any other medication should only be considered on the advice of an experienced and knowledgeable veterinary professional. It's also important to closely observe the pet's response to the medication, as individual reactions can vary widely. If you have any questions about the potential uses of Cisapride 10 mg Oral Capsules or any other formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our expert team of compounding pharmacists will be happy to provide you with the information and guidance you need.

Frequently Asked Questions

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What is the Cisapride 10 mg Oral Capsule (Vet)?

The Cisapride 10 mg Oral Capsule is a compounded veterinary medication provided as a solid dosage form. It consists of two easy-to-swallow shells, either made of gelatin or vegetarian-friendly material, that enclose the medication.

How does the capsule ensure a precise dosage?

Each Cisapride 10 mg Oral Capsule is specifically designed to contain exactly 10 mg of the active ingredient. This controlled dose ensures accurate medication administration for pets.

Is this medication difficult for pets to swallow?

These capsules are created with smooth gelatin or vegetarian shells, enabling easy and convenient swallowing for pets. This makes the medicine administration process simpler for the pet owners as well.

Is the gelatin shell of this capsule animal-based?

Some capsules may use gelatin, which is often animal-based. However, for those with dietary restrictions or preferences, a vegetarian shell option is also available.

What is the active ingredient in these capsules?

The active ingredient within these capsules is Cisapride, which is useful in veterinary medicine, particularly for gastrointestinal disorders.

Do the shells contain any active medication?

No, the shells do not contain any of the active medication. They serve purely to encase the active ingredient for precision dosing and ease of swallowing.

Can the capsule be opened and mixed with food?

While it depends on the specific instructions from the vet, generally the capsules are designed to be given whole. Opening them can disrupt the precise measurement of the medication.

How should these capsules be stored?

Cisapride capsules should be stored in a dry and cool place, away from direct sunlight. Always ensure the containers are tightly closed to maintain their potency and effectiveness.

What if my pet vomits or spits out the capsule?

If your pet vomits or spits out the capsule shortly after administration, it's best to consult your vet. They might provide specific instructions or alternatives to ensure your pet receives their necessary medication.

What happens if I accidentally miss a dose for my pet?

If you miss a dose, give it as soon as possible. However, if it's near the time for the next dose, skip it and go back to your regular schedule. Never give your pet two doses at once. Always consult with your vet if you have any concerns.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.