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Cimetidine 5%/Ibuprofen 2%/Salicylic Acid 60%/Trichloroacetic Acid 1% Topical Paste

This formulation is a topical paste composed of Cimetidine 5%, Ibuprofen 2%, Salicylic Acid 60%, and Trichloroacetic Acid 1%. It is a semi-solid formulation dispensed in a tube, designed for external application to the skin. The paste provides a thick and occlusive consistency that adheres to the skin surface, delivering medication, protective barriers, or other active ingredients for localized treatment or wound care.

The formulation offers ease of application and precise dosage control. It is used to treat a variety of disease states, including inflammation, pain, warts, and other skin conditions. The Cimetidine acts as a histamine blocker, reducing inflammation and promoting healing. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that helps to reduce pain and inflammation. Salicylic Acid is a keratolytic (peeling agent) that causes shedding of the outer layer of skin, useful in treating warts and other skin conditions. Trichloroacetic Acid is used in dermatology for chemical peeling and for the treatment of warts, scars, and other skin disorders.

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Topical Paste
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Formula Information

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This formulation is a combination of Cimetidine, Ibuprofen, Salicylic Acid, and Trichloroacetic Acid, each serving a unique therapeutic purpose. Cimetidine is a histamine H2-receptor antagonist that inhibits stomach acid production, and is commonly used in the treatment of heartburn and peptic ulcers. In this topical formulation, it may help to reduce inflammation and promote healing of the skin.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. When applied topically, it can help to reduce localized pain and inflammation. Salicylic Acid is a keratolytic (peeling agent) that causes shedding of the outer layer of skin. It is used to treat conditions such as acne, psoriasis, dandruff, and warts, as well as other skin conditions that involve scaling or overgrowth of skin cells.

Trichloroacetic Acid is a chemical cauterant that can be used to destroy skin lesions. It works by coagulating the proteins in the tissue, which leads to necrosis of the individual cells. This can be useful in the treatment of warts, skin tags, and other benign skin growths.

This formulation is dispensed in a semi-solid paste form, which provides a thick and occlusive consistency that adheres well to the skin surface. This allows for the delivery of the medication directly to the area of the skin that requires treatment, providing a localized effect. The paste form also offers ease of application and precise dosage control, making it a convenient option for both patients and prescribers.

It is important to note that this formulation should only be used externally and should not be applied to broken skin or open wounds. As with any medication, it is important to use this product as directed by your healthcare provider, and to report any side effects or adverse reactions that you may experience.

If you have any questions about this formulation, or if you would like more information about how it can be used to treat specific skin conditions, please do not hesitate to reach out to us. Our team of compounding pharmacists at Bayview Pharmacy is always here to help.

Drug Interactions

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This formulation contains Cimetidine, Ibuprofen, Salicylic Acid, and Trichloroacetic Acid. Each of these active ingredients can interact with other medications, potentially altering their effects. It's important to inform your healthcare provider about all the medications you're currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements.

Cimetidine may interact with certain medications such as warfarin, phenytoin, theophylline, and lidocaine, potentially increasing their levels in the body and leading to side effects. It can also interact with certain antifungal medications, reducing their effectiveness.

Ibuprofen may interact with medications such as aspirin, anticoagulants, antiplatelet drugs, and certain antihypertensives. It can increase the risk of bleeding when taken with anticoagulants or antiplatelet drugs. When taken with certain antihypertensives, it may reduce their effectiveness.

Salicylic Acid may interact with other topical medications, especially those containing alcohol, resorcinol, or sulfur. Using these medications together may lead to increased skin irritation. It can also interact with blood thinners, increasing the risk of bleeding.

Trichloroacetic Acid may interact with other topical medications, potentially leading to skin irritation or damage. It's important to inform your healthcare provider about any other topical products you're using.

This formulation is designed to treat a variety of skin conditions. Cimetidine is an H2 blocker that can help reduce inflammation and promote healing. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can help reduce pain and inflammation. Salicylic Acid is a keratolytic agent that can help remove dead skin cells and unclog pores. Trichloroacetic Acid is a chemical peel that can help remove the outer layers of the skin, promoting new skin growth.

It's important to use this medication exactly as directed by your healthcare provider. Avoid applying it to broken skin or open wounds unless directed by your healthcare provider. If you experience any unusual side effects, such as severe skin irritation, discontinue use and contact your healthcare provider immediately.

If you have any questions about this formulation or its potential interactions, don't hesitate to reach out to us. We're here to help ensure that you're using this medication safely and effectively.

How Does it Work

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This formulation is a combination of four active ingredients: Cimetidine, Ibuprofen, Salicylic Acid, and Trichloroacetic Acid, each playing a unique role in the treatment of various disease states.

Cimetidine, a histamine H2-receptor antagonist, works by reducing the amount of acid produced in the stomach. In this topical formulation, it is used for its potential antiviral and immune-modulating properties. It may help to reduce inflammation and promote healing in the skin.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. When applied topically, it can help to reduce localized pain and inflammation in the skin.

Salicylic Acid is a keratolytic (peeling agent) that causes shedding of the outer layer of skin. It is used to treat conditions such as acne, psoriasis, dandruff, and warts, as well as other skin conditions that involve scaling or overgrowth of skin cells. In this formulation, it helps to break down the thick, rough skin often associated with warts, calluses, and other skin conditions.

Trichloroacetic Acid is a chemical cauterant that can be used to treat a variety of skin conditions. It works by coagulating the proteins in the skin, causing the skin to dry and peel off. This can help to remove warts, skin tags, and other skin lesions.

The semi-solid paste formulation is designed to adhere to the skin surface, providing a localized treatment that can be easily applied and controlled. The occlusive consistency of the paste helps to protect the skin and keep the active ingredients in contact with the skin for a longer period of time, enhancing their effectiveness.

This formulation can be used to treat a variety of skin conditions, including warts, calluses, skin tags, and other skin lesions. It can also be used to reduce inflammation and promote healing in the skin. As with any medication, it should be used under the supervision of a healthcare provider, and any questions or concerns should be addressed to your pharmacist or healthcare provider.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. We are a team of knowledgeable compounding pharmacists, and we are here to help you understand your medications and how they work.

Other Uses

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Aside from the indicated uses, this multi-component topical paste may also possess other potential benefits due to the individual properties of its active ingredients. Ibuprofen and Cimetidine, being anti-inflammatory and antacid agents respectively, could potentially be utilized off-label for symptomatic relief in certain cutaneous conditions manifested by inflammation and/or acidity, such as insect bites, stings, or minor burns. The addition of Salicylic acid, a well-known keratolytic and desquamative agent, broadens its potential utilities to include conditions characterized by hyperkeratosis such as warts, calluses or corns.

Trichloroacetic Acid (TCA) 1% also lends value to this preparation due to its applications in various cosmetic procedures such as chemical peeling. It has been used widely for the treatment of conditions like acne, melasma, photoaging, and even superficial skin malignancies. Its presence in the formulation suggests it may be used as a part of at-home skincare regimen to improve hyperpigmentation, fine lines and skin texture, always under careful supervision.

Ultimately, the prescriber should individualize treatment depending on the patient's specific condition, only considering off-label use when no other viable, approved treatment options exist and the anticipated benefits outweigh potential risks. It should be noted that despite promising evidence, these additional uses may not have been systematically studied or fully established. Therefore, clinicians and patients must always approach off-label usage with caution. To get further information or to clarify any doubts, don't hesitate to reach out to us at Bayview Pharmacy, where our dedicated team of compounding pharmacists are ready to assist.

Frequently Asked Questions

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What is this topical paste used for?

This compounded paste is designed for external application to the skin. It can provide localized treatment, wound care, and act as a protective barrier. It contains Cimetidine, Ibuprofen, Salicylic Acid, and Trichloroacetic Acid which offer various therapeutic effects.

What specific skin conditions can this topical paste be used for?

As a compounded medication, this cream can be designed to treat a variety of skin conditions based on physician guidance. Cimetidine, ibuprofen, salicylic acid, and trichloroacetic acid can help address issues like inflammation, pain, warts, and corns. However, exact application should be determined in consultation with your healthcare provider.

How do I properly apply this cream?

This topical paste should be applied as directed by your physician, often to the affected area on the skin. Its semi-solid formulation allows for precise dosage control, and it should adhere well to the skin surface for a localized treatment.

Are there any potential side effects?

All medications have the potential for side effects. Some possibilities with these ingredients may include skin irritation, redness, or a burning sensation. If you notice any unusual side effects, it's best to consult your healthcare provider.

Is the paste absorbed into the skin, or does it sit on the skin surface?

This paste is designed to adhere well to the skin surface for localized treatment. Depending on the prescribing advice, it may also offer some degree of absorption to deliver medication to deeper layers of skin.

Does this cream need to be refrigerated?

Specific storage information will be provided by your pharmacist. However, most topical pastes do not typically need to be refrigerated.

What does a compounded medication mean?

A compounded medication is a unique formulation made to cater to the specific needs of a patient, unlike mass-produced medications. This might be needed if the standard treatments are not appropriate, or if a different method of delivery (like a paste instead of a tablet) is required.

Can anyone use this topical paste?

Like all prescription medications, this paste should only be used by the person it was prescribed to, and in the manner instructed by a healthcare provider.

What does the percentage next to each ingredient signify?

The percentage next to each active ingredient represents the concentration of that ingredient in the overall formulation. For instance, the paste is composed of 60% Salicylic Acid.

Can I apply other topicals with this paste?

Other topicals should only be applied with this paste if directed by a healthcare provider. Mixing medications could impact the efficacy of treatments, cause interactions, and increase the risk of side effects.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.