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Cholestyramine 10%/Nystatin 10%/Zinc Oxide 10% Topical Ointment

This Cholestyramine 10%/Nystatin 10%/Zinc Oxide 10% Topical Ointment is a semi-solid formulation dispensed in a tube for external application. The greasy or oily base aids in the delivery of the active ingredients to the skin for localized treatment. Cholestyramine is used to treat skin inflammation, Nystatin is an antifungal medication used to treat skin infections, and Zinc Oxide promotes wound healing. This combination of ingredients makes it an effective treatment for a variety of skin conditions.

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Topical Ointment
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Formula Information

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This formulation is a combination of Cholestyramine 10%, Nystatin 10%, and Zinc Oxide 10% in a topical ointment. It is a semi-solid preparation that is dispensed in a tube for external application to the skin. The greasy or oily base of the ointment aids in the delivery of the medication, providing localized treatment for a variety of skin conditions.

Cholestyramine is a bile acid sequestrant that is typically used to lower high levels of cholesterol in the blood. However, in this topical formulation, it can help to bind and remove irritants from the skin surface, reducing inflammation and promoting healing.

Nystatin is an antifungal medication that works by stopping the growth of fungus. It is used to treat skin infections caused by yeast. Nystatin binds to sterols in the cell membrane of susceptible Candida species, disrupting the cell membrane and leading to fungal cell death.

Zinc Oxide is a skin protectant that provides a barrier against irritants and helps to soothe and protect the skin. It is commonly used in treating minor skin irritations, burns, and wounds. Zinc Oxide also has mild astringent properties and some antiseptic action, making it beneficial for a variety of skin conditions.

This combination of Cholestyramine, Nystatin, and Zinc Oxide in a topical ointment can be used to treat a variety of skin conditions, including skin inflammation, infections, and wounds. The ointment should be applied as directed by a healthcare provider, typically in a thin layer to the affected area of the skin.

As with any medication, it is important to use this formulation as directed by a healthcare provider and to report any side effects or adverse reactions. It is also important to inform the healthcare provider of any other medications or supplements being taken, as there may be potential interactions.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Drug Interactions

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This formulation contains three active ingredients: Cholestyramine, Nystatin, and Zinc Oxide. Each of these ingredients has a specific role in treating various skin conditions, but they may also interact with other medications. It's important to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter products, and herbal supplements.

Cholestyramine is a bile acid sequestrant that is primarily used to lower high levels of cholesterol in the blood. However, in this topical formulation, it can help to absorb and remove certain toxins from the skin. Cholestyramine may interact with other medications, reducing their absorption and effectiveness. This includes certain types of heart medications, thyroid hormones, and certain vitamins such as A, D, E, and K. It's important to take other medications at least 1 hour before or 4 to 6 hours after applying this ointment to avoid interactions.

Nystatin is an antifungal medication used to treat skin infections caused by yeast. Nystatin may interact with other topical medications, especially those that can cause skin irritation or dryness. Using Nystatin with other skin products may increase the risk of severe skin irritation. Therefore, it's important to inform your healthcare provider about all the skin products you are currently using.

Zinc Oxide is a skin protectant that provides a barrier against moisture and irritants. It also has mild astringent and antiseptic properties. Zinc Oxide is generally considered safe and does not usually interact with other medications. However, it's still important to inform your healthcare provider about all the medications you are currently taking.

This formulation is designed to treat various skin conditions such as skin inflammation, infections, and aid in wound healing. Cholestyramine helps to remove toxins from the skin, Nystatin treats fungal infections, and Zinc Oxide provides a protective barrier and promotes healing. However, like all medications, it should be used under the supervision of a healthcare provider to ensure its safe and effective use.

If you have any questions about this formulation or its potential interactions with other medications, please don't hesitate to reach out to us. We are here to help and provide you with the most accurate and up-to-date information.

How Does it Work

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The Cholestyramine 10%/Nystatin 10%/Zinc Oxide 10% Topical Ointment is a unique formulation that combines the therapeutic benefits of three active ingredients to treat a variety of skin conditions. This semi-solid formulation is designed for external application to the skin, providing a greasy or oily base that aids in the delivery of medication for localized treatment.

Cholestyramine is a bile acid sequestrant that works by binding to bile acids in your intestines to form a product that is removed from the body. In this topical formulation, it is used for its ability to bind to certain toxins or irritants on the skin surface, thereby reducing inflammation and irritation. It is particularly useful in treating conditions such as pruritus (itching) associated with certain skin diseases.

Nystatin is an antifungal medication that works by stopping the growth of fungus. It binds to sterols in the cell membrane of susceptible Candida species, disrupting the cell wall and leading to fungal cell death. This makes it an effective treatment for cutaneous or mucocutaneous mycotic infections caused by Candida (Monilia) species.

Zinc Oxide is a skin protectant that provides a barrier against moisture and irritants. It also has mild astringent and antiseptic properties. Zinc Oxide is commonly used to treat and prevent diaper rash, but it can also be used to promote the healing of chapped skin and minor skin irritations (e.g., burns, cuts, scrapes).

Together, these three active ingredients provide a comprehensive treatment approach for a variety of skin conditions. The ointment base ensures that the active ingredients stay in contact with the skin for a prolonged period, allowing for effective treatment of the affected area.

As with any medication, it is important to use this product as directed by your healthcare provider. If you have any questions about this formulation or how to use it, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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This unique formulation of Cholestyramine 10%/Nystatin 10%/Zinc Oxide 10% Topical Ointment has potential for other therapeutic uses beyond its traditional role in skin inflammation, infections, or wound healing. For patients and prescribers exploring alternative applications, please bear the following in mind.

Given the specific compounds in this product, it could be utilized for other skin conditions where there is a need for astringent, antifungal, or bile acid sequestrant properties. The presence of Zinc Oxide, an effective astringent, makes it a potential treatment for conditions like rosacea, eczema, rashes, or acne, where there is a need to alleviate inflammation and soothe the skin. Its capability to create a protective layer on the skin can also help in preventing excessive moisture loss and protect from environmental irritants.

Considering the antifungal characteristics of Nystatin, this ointment could be used for treating a variety of fungal skin infections beyond its typical use. This includes conditions like ringworm, athlete's foot, or jock itch, which are caused by fungi that could potentially be susceptible to Nystatin.

The inclusion of Cholestyramine, a bile acid sequestrant, may make this ointment suitable for treating pruritus, or severe itching, particularly associated with liver disease where bile salts are contributing to the problem. Applying an ointment containing a bile acid sequestrant may help alleviate the discomfort and itching associated with these conditions.

However, it is crucial for patients and prescribers to remember that although this formulation shows potential for these additional uses, further research and clinical trials may be required to definitively establish efficacy and safety for these conditions. Always consult with a healthcare professional before initiating a new treatment regimen. As compounding pharmacists, we are more than happy to answer any questions you may have regarding this product's versatility and utility. Reach out to us at Bayview Pharmacy for further clarification and guidance.

Frequently Asked Questions

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What is Cholestyramine 10%/Nystatin 10%/Zinc Oxide 10% Topical Ointment?

This is a specially compounded ointment designed to deliver the medicinal benefits of Cholestyramine, Nystatin, and Zinc Oxide through the skin. These ingredients are combined into a greasy or oily base and dispensed in a tube for easy external application.

What is the purpose of this ointment?

The ointment is typically used for the localized treatment of skin conditions like inflammation and infections. It's also used to promote wound healing.

How should this ointment be applied?

It should be applied externally on the skin, onto the affected area. It's important to follow your healthcare professional's instructions for use, as they may vary depending on the specific condition.

Does this ointment have any side effects?

As with any medication, this ointment can have side effects. While they're usually mild and manageable, it's crucial to inform your healthcare provider if you notice any unusual or severe reactions after its application.

Can this ointment be used simultaneously with other medications?

Whether or not it can be used along with other medications depends on the nature of those medications. Always inform your healthcare provider about all the medications you're currently taking to avoid adverse interactions.

What does an oily or greasy base do?

An oily or greasy base helps in efficiently delivering the medicine into your skin. It also creates a protective barrier on your skin which aids the healing process.

What should I do if I have a reaction to the ointment?

If you have a reaction to the ointment, stop using it immediately and contact your healthcare provider. They will provide you with guidance on how to manage the reaction and what steps to take next.

How does the ointment work to combat skin inflammation and infections?

The Cholestyramine component helps reduce inflammation. Nystatin is an antifungal useful in treating infections, and Zinc Oxide helps in wound healing and offers adjuvant skin protection.

What is the proper way to store this ointment?

For optimum effectiveness of the active ingredients, the ointment should be stored in a cool, dry place, ideally as per the instructions provided. It should also be kept out of reach of children.

Is a prescription needed for Cholestyramine 10%/Nystatin 10%/Zinc Oxide 10% Topical Ointment?

Yes, a prescription from a qualified healthcare provider is needed to acquire this compound ointment, as it contains medicinal ingredients.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.