Chlorpromazine HCl 27.75 mg Rectal Suppository is a specialized formulation designed for rectal administration. This solid dosage form is inserted into the rectum, where it dissolves or melts to release the medication. The active ingredient, Chlorpromazine HCl, is then absorbed locally or systemically to exert its therapeutic effects.

Chlorpromazine HCl is a type of medication known as a phenothiazine antipsychotic. It works by adjusting the balance of chemicals in the brain to help improve mood, reduce anxiety, and manage psychotic or mental disorders. This medication is commonly used to treat conditions such as schizophrenia, manic-depression, and severe behavioral problems in children. It can also be used to prevent and treat nausea and vomiting, relieve ongoing hiccups, relieve restlessness and anxiety before surgery, and aid in the treatment of tetanus.

As a rectal suppository, this formulation offers several advantages. It can be particularly useful for patients who have difficulty swallowing oral medications, are nauseous, vomiting, or unconscious. The rectal route also bypasses the first-pass metabolism in the liver, potentially increasing the bioavailability of the medication. However, it's important to note that the absorption of medication via the rectal route can be variable and may be influenced by factors such as the presence of stool in the rectum.

Patients using this formulation should follow the instructions provided by their healthcare provider or pharmacist. The suppository should be inserted into the rectum as directed, usually 2 to 3 times daily or as directed by your doctor. It's important to wash hands before and after using this product. If the suppository is too soft to insert, chill it in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper.

Side effects may include drowsiness, dizziness, dry mouth, blurred vision, or constipation. If any of these effects persist or worsen, patients should inform their doctor or pharmacist promptly. It's important to remember that the doctor has prescribed this medication because they have judged that the benefit to the patient is greater than the risk of side effects.

Prescribers should consider the patient's overall health status, other medications, and disease state before prescribing this formulation. Regular monitoring of the patient's response to therapy and side effects is recommended. Dose adjustments may be necessary based on the patient's condition and tolerance to the medication.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Chlorpromazine HCl is an antipsychotic medication that works by altering the actions of certain chemicals in the brain. It is used to treat certain mental or mood disorders, such as schizophrenia, psychotic disorders, manic phase of bipolar disorder, and severe behavioral problems in children. It can also be used to prevent and treat nausea and vomiting, relieve ongoing hiccups, relieve restlessness and anxiety before surgery, and aid in the treatment of tetanus.

Chlorpromazine HCl can interact with a number of other medications, potentially altering their effects or increasing the risk of side effects. It is important for patients and prescribers to be aware of these potential interactions.

Chlorpromazine HCl can interact with other antipsychotic medications, such as clozapine, and increase the risk of serious side effects such as seizures. It can also interact with medications for Parkinson's disease, such as levodopa, reducing their effectiveness. If you are taking any medications for Parkinson's disease, discuss this with your healthcare provider before starting treatment with Chlorpromazine HCl.

This medication can also interact with certain medications for depression, such as fluoxetine and paroxetine, potentially increasing the risk of side effects such as drowsiness, dizziness, and difficulty concentrating. If you are taking any antidepressants, it is important to discuss this with your healthcare provider before starting treatment with Chlorpromazine HCl.

Chlorpromazine HCl can also interact with certain medications for heart conditions, such as beta-blockers and calcium channel blockers, potentially increasing the risk of side effects such as low blood pressure and slow heart rate. If you are taking any medications for heart conditions, discuss this with your healthcare provider before starting treatment with Chlorpromazine HCl.

It is important to inform your healthcare provider about all the medications you are currently taking, including prescription and over-the-counter medications, vitamins, and herbal supplements, to avoid potential drug interactions. Do not start or stop any medication without consulting your healthcare provider.

Alcohol can increase the risk of side effects from Chlorpromazine HCl, such as drowsiness and dizziness. It is recommended to avoid or limit the use of alcohol while taking this medication.

Chlorpromazine HCl can make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.

If you have any questions about the potential drug interactions with Chlorpromazine HCl, do not hesitate to reach out to us. We are here to help you understand your medication and ensure that it is safe and effective for you.

Chlorpromazine HCl 27.75 mg Rectal Suppository is a solid dosage form that is inserted into the rectum, where it dissolves or melts to release the medication. The active ingredient, Chlorpromazine HCl, is a type of drug known as a phenothiazine antipsychotic. It works by affecting the balance of natural chemicals (neurotransmitters) in the brain to produce a calming and antiemetic effect.

Once the suppository is inserted into the rectum, it begins to dissolve due to the body's natural heat. As it dissolves, the Chlorpromazine HCl is released and absorbed through the rectal tissue into the bloodstream. This allows the medication to be distributed throughout the body, where it can exert its effects on the brain and other parts of the body.

Chlorpromazine HCl is used to treat a variety of conditions, including certain mental/mood disorders (such as schizophrenia, psychosis), severe behavioral problems in children, and certain types of nausea and vomiting. It can also be used to help control prolonged hiccups, relieve restlessness and anxiety before surgery, and treat tetanus. It works by helping to restore the balance of certain natural substances in the brain.

It's important to note that this medication should be used under the supervision of a healthcare provider, as it can have side effects and may interact with other medications. The dose and duration of treatment will depend on the patient's condition and response to therapy. It's also important to use this medication regularly to get the most benefit from it. To help you remember, use it at the same time(s) each day.

If you have any questions about this formulation, how to use it, or its effects, don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help you understand your medication and how it works to treat your condition.

In addition to the primary indications, Chlorpromazine HCl 27.75 mg Rectal Suppository may also have certain other uses. This medication may be employed off-label to manage severe cases of hiccups that do not respond to conventional therapy. Chlorpromazine, given its antipsychotic properties, can also be used to control severe anxiety or anxiety disorders, especially those associated with psychosis. Furthermore, it can also be utilized as a part of palliative care in terminal illnesses for controlling restlessness, agitation, or delirium in the end stage diseases.

Also, Chlorpromazine, because of its antiemetic properties, can be used to control severe nausea and vomiting triggered by specific medical treatments, such as chemotherapy or radiation, or conditions like hyperemesis gravidarum in pregnancy. However, it’s important to remember that the usage in pregnancy should be reserved for cases where the benefit outweighs the potential risk to the fetus. In certain scenarios, it can be used as an adjunct in preoperative sedation as well.

Finally, it's important to note that the rectal route of administration offers certain benefits over oral administration, especially in individuals who are nauseous or unable to swallow, or for those who cannot tolerate medications via the oral route. Nonetheless, the use of this medication must be monitored closely due to its potential for side effects and must be under the supervision of a healthcare provider. As always, the potential risks and benefits must be considered when prescribing this medication, and it's essential to ensure that the use is appropriate for the patient's condition.

Please feel free to reach out to us if you have any questions. Our team of knowledgeable pharmacists here at Bayview Pharmacy are always ready to help and provide further information as needed.