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Formulas

Chlorpheniramine Maleate 0.2 mg/mL/Deoxy D Glucose 1 mg/mL/Lidocaine HCl 10 mg/mL/Nystatin 1.9 mg/mL/Tetracycline HCl 12 mg/mL Oral Suspension

This oral suspension is a liquid dosage form in which Chlorpheniramine Maleate, Deoxy D Glucose, Lidocaine HCl, Nystatin, and Tetracycline HCl are uniformly dispersed throughout a liquid medium, ensuring a homogeneous mixture for administration.

It is specifically formulated to treat a range of disease states, including allergic reactions, fungal infections, bacterial infections, and pain relief. The combination of active ingredients provides comprehensive therapeutic effects, addressing multiple symptoms and conditions effectively.

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Chlorpheniramine Maleate
Lidocaine Hydrochloride
Nystatin
Tetracycline Hydrochloride
Deoxy-D-Glucose
Suspension
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Formula Information

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This compounded oral suspension is a specially formulated medication that combines Chlorpheniramine Maleate 0.2 mg/mL, Deoxy D-Glucose 1 mg/mL, Lidocaine HCl 10 mg/mL, Nystatin 1.9 mg/mL, and Tetracycline HCl 12 mg/mL. Each ingredient plays a unique role in addressing various symptoms and conditions, providing a multifaceted approach to treatment.

Chlorpheniramine Maleate is an antihistamine that works by blocking the action of histamine, a substance in the body that causes allergic symptoms. By reducing histamine levels, it helps alleviate symptoms such as itching, swelling, and rashes.

Deoxy D-Glucose is a glucose analog that may interfere with the metabolism of certain pathogens. Its inclusion in the formulation can help inhibit the growth of microorganisms by disrupting their energy production processes.

Lidocaine HCl is a local anesthetic that provides rapid pain relief by numbing the affected area. In an oral suspension, it can help ease discomfort in the mouth or throat, making it beneficial for conditions that cause irritation or soreness.

Nystatin is an antifungal agent effective against a variety of yeast and fungi, particularly Candida species. It works by binding to the fungal cell membrane, causing leakage of cellular contents and ultimately leading to cell death. This makes it useful in treating oral thrush and other fungal infections in the oral cavity.

Tetracycline HCl is a broad-spectrum antibiotic that inhibits protein synthesis in bacteria, preventing their growth and multiplication. It is effective against a wide range of bacterial infections and can help in managing bacterial components of mixed infections.

The liquid suspension form ensures uniform distribution of all active ingredients throughout the medium, allowing for accurate dosing and improved patient compliance. This is especially helpful for individuals who have difficulty swallowing tablets or capsules.

This comprehensive formulation is designed to address multiple symptoms and pathogens simultaneously. By combining an antihistamine, antifungal, antibiotic, and anesthetic, it offers a targeted approach to complex conditions that involve allergic reactions, infections, and pain.

Patients prescribed this medication should use it exactly as directed by their healthcare provider. It is important to complete the full course of treatment, even if symptoms improve, to ensure the effectiveness of the therapy and to prevent the development of resistant organisms.

If you have any questions, reach out to us.

Drug Interactions

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This compounded oral suspension contains a combination of Chlorpheniramine Maleate, Deoxy D Glucose, Lidocaine HCl, Nystatin, and Tetracycline HCl, each contributing to the treatment of various disease states. However, the potential for drug interactions must be carefully considered by both patients and prescribers to ensure safe and effective use.

Chlorpheniramine Maleate, an antihistamine, may interact with other central nervous system depressants such as alcohol, sedatives, and tranquilizers, potentially enhancing their sedative effects. Patients should be advised to avoid or limit the use of these substances while taking this formulation. Additionally, Chlorpheniramine may interact with monoamine oxidase inhibitors (MAOIs), leading to increased anticholinergic effects, and should not be used concurrently with MAOIs or within two weeks of discontinuing such therapy.

Deoxy D Glucose, a glucose analog, generally has a low potential for drug interactions. However, patients with diabetes or those on medications affecting blood glucose levels should be monitored closely, as this component may influence glucose metabolism and insulin sensitivity.

Lidocaine HCl, a local anesthetic, can interact with antiarrhythmic drugs, such as amiodarone and mexiletine, potentially leading to additive cardiac effects. Caution is advised when this formulation is used in patients receiving such medications. Additionally, Lidocaine may enhance the effects of other local anesthetics and should be used with caution in combination with them.

Nystatin, an antifungal agent, is generally well-tolerated with a low risk of systemic drug interactions due to its minimal absorption from the gastrointestinal tract. However, prescribers should be aware of the potential for interactions with other antifungal agents, which may alter the efficacy of treatment.

Tetracycline HCl, an antibiotic, has several notable interactions. It can bind to divalent and trivalent metal ions such as calcium, magnesium, and iron, which can significantly reduce its absorption. Patients should be advised to avoid taking this formulation with dairy products, antacids, or supplements containing these ions. Tetracycline may also interact with oral contraceptives, potentially reducing their effectiveness, and patients should be counseled on using additional contraceptive methods. Furthermore, concurrent use with isotretinoin should be avoided due to the increased risk of intracranial hypertension.

Overall, this compounded formulation requires careful consideration of potential drug interactions. Patients and prescribers should maintain open communication and monitor for any adverse effects or changes in therapeutic efficacy. If you have any questions or concerns regarding the use of this formulation, please reach out to us at Bayview Pharmacy for further guidance.

How Does it Work

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This compounded oral suspension is a carefully formulated medication designed to address multiple symptoms and conditions through the synergistic action of its active ingredients. Each component plays a specific role in managing symptoms and treating underlying causes, providing a comprehensive therapeutic approach.

Chlorpheniramine Maleate, at a concentration of 0.2 mg/mL, is an antihistamine that works by blocking the action of histamine, a substance in the body that causes allergic symptoms. By inhibiting histamine receptors, it helps alleviate symptoms such as runny nose, sneezing, and itching, making it effective in treating allergic reactions and conditions like hay fever or allergic rhinitis.

Deoxy D Glucose, included at 1 mg/mL, serves as a metabolic substrate that can be utilized by cells for energy production. In certain disease states, such as infections or inflammatory conditions, cells may require additional energy to function optimally. Deoxy D Glucose supports cellular metabolism, potentially enhancing the body's ability to fight infections and recover from illness.

Lidocaine HCl, present at 10 mg/mL, is a local anesthetic that provides relief from pain and discomfort. It works by blocking nerve signals in the body, which helps to numb the area and reduce pain sensations. This can be particularly beneficial in conditions where pain management is necessary, such as oral ulcers or throat irritation, providing symptomatic relief and improving patient comfort.

Nystatin, at a concentration of 1.9 mg/mL, is an antifungal agent that targets fungal infections, particularly those caused by Candida species. It works by binding to sterols in the fungal cell membrane, creating pores that lead to cell leakage and ultimately cell death. This action makes it effective in treating oral thrush and other fungal infections of the mouth and throat, helping to restore a healthy microbial balance.

Tetracycline HCl, included at 12 mg/mL, is a broad-spectrum antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. This action prevents the growth and multiplication of bacteria, making it effective against a wide range of bacterial infections. It is particularly useful in treating infections of the respiratory tract, skin, and soft tissues, as well as certain types of oral infections.

The liquid dosage form of this suspension ensures that the active ingredients are dispersed uniformly throughout the liquid medium, providing a homogeneous mixture for administration. This allows for precise dosing and easy administration, especially for patients who may have difficulty swallowing tablets or capsules. The formulation is designed to maximize the therapeutic effects of each component while minimizing potential side effects, offering a balanced approach to treatment.

If you have any questions about this formulation or its use in treating specific disease states, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need.

Other Uses

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This compounded oral suspension, containing Chlorpheniramine Maleate, Deoxy D Glucose, Lidocaine HCl, Nystatin, and Tetracycline HCl, is primarily formulated for specific therapeutic purposes. However, beyond its primary indications, this formulation may have other potential uses that could be considered by healthcare providers based on their clinical judgment and patient-specific needs. Chlorpheniramine Maleate, an antihistamine, is typically used to relieve allergy symptoms, but it may also be considered for off-label use in managing symptoms of the common cold, such as sneezing and runny nose, due to its ability to reduce histamine activity. Deoxy D Glucose, while primarily used for its energy-providing properties, may also be explored in research settings for its potential role in modulating cellular metabolism, although such uses would be highly experimental and should be approached with caution.

Lidocaine HCl, a local anesthetic, is included in this formulation to provide topical pain relief. While its primary use is to alleviate discomfort in the oral cavity, it may also be considered for other types of localized pain relief in the mouth or throat, such as that associated with minor oral procedures or injuries. Nystatin, an antifungal agent, is primarily used to treat fungal infections, particularly those caused by Candida species. However, it may also be considered for prophylactic use in patients at high risk of developing oral thrush, such as those undergoing chemotherapy or long-term antibiotic therapy, although this should be done under careful medical supervision.

Tetracycline HCl, an antibiotic, is included for its broad-spectrum antibacterial properties. While it is primarily used to treat bacterial infections, it may also be considered for off-label use in managing certain inflammatory conditions due to its anti-inflammatory properties, such as in the treatment of acne or rosacea, although such uses would typically involve topical rather than oral administration. It is important for prescribers to weigh the benefits and risks of using this formulation for any off-label purposes, considering factors such as patient history, potential side effects, and drug interactions.

Patients and prescribers should be aware that while this compounded formulation offers a unique combination of active ingredients, its use should be guided by a thorough understanding of each component's pharmacological profile and the specific needs of the patient. As with any medication, adherence to prescribed dosages and monitoring for adverse effects is crucial. If you have any questions or require further information about this formulation and its potential uses, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries you may have.

Frequently Asked Questions

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What is the purpose of this compounded oral suspension?

This compounded oral suspension is designed to deliver a combination of active ingredients, including Chlorpheniramine Maleate, Deoxy D Glucose, Lidocaine HCl, Nystatin, and Tetracycline HCl, each serving a specific therapeutic purpose. It is used to treat various conditions as prescribed by a healthcare provider.

How should I store this oral suspension?

Store the oral suspension in a cool, dry place away from direct sunlight and out of reach of children. Follow any specific storage instructions provided by your pharmacist or healthcare provider.

How do I properly administer this oral suspension?

Shake the bottle well before each use to ensure the ingredients are evenly distributed. Use the measuring device provided to ensure accurate dosing. Follow your healthcare provider's instructions regarding dosage and frequency.

Can I take this oral suspension with other medications?

Before taking this oral suspension with other medications, consult your healthcare provider or pharmacist to avoid potential interactions. They can provide guidance based on your specific medication regimen.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Are there any side effects associated with this oral suspension?

Possible side effects may include drowsiness, nausea, or allergic reactions. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Is this oral suspension safe for children?

The safety and dosage of this oral suspension for children should be determined by a healthcare provider. Always follow the guidance of a healthcare professional when administering medication to children.

Can pregnant or breastfeeding women use this oral suspension?

Pregnant or breastfeeding women should consult their healthcare provider before using this oral suspension to ensure it is safe for them and their baby.

What should I do in case of an overdose?

In case of an overdose, seek immediate medical attention or contact a poison control center. Provide them with as much information as possible about the medication and the amount taken.

How long can I use this oral suspension after opening?

The shelf life of the oral suspension after opening can vary. Check the label for specific expiration information or consult your pharmacist for guidance on how long the suspension remains effective after opening.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.