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Formulas

Chloramphenicol 1%/Hydrocortisone 0.5%/Niacinamide 3%/Sulfur 7.8% Topical Cream

This formulation is a semisolid preparation of Chloramphenicol 1%, Hydrocortisone 0.5%, Niacinamide 3%, and Sulfur 7.8% dispensed in a pump mechanism. It is designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients. The formulation is used to treat various disease states including bacterial skin infections, inflammation, acne, and rosacea. Chloramphenicol is an antibiotic that fights bacteria, Hydrocortisone is a corticosteroid that reduces inflammation, Niacinamide is a form of vitamin B3 that improves skin health, and Sulfur is a keratolytic agent that helps shed dead skin cells and unclog pores.

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Topical Cream
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Formula Information

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This formulation is a compounded topical cream containing Chloramphenicol 1%, Hydrocortisone 0.5%, Niacinamide 3%, and Sulfur 7.8%. It is dispensed in a pump mechanism for easy and controlled application on the skin. The cream is designed to deliver localized treatment, allowing the active ingredients to be absorbed directly into the affected area.

Chloramphenicol is a broad-spectrum antibiotic that is effective against a wide range of bacteria. It works by inhibiting bacterial protein synthesis, thereby stopping the growth and multiplication of bacteria. This makes it useful in treating various bacterial skin infections.

Hydrocortisone is a corticosteroid that works by reducing inflammation, itching, and redness. It is commonly used to treat a variety of skin conditions such as eczema, dermatitis, allergies, and rash. The inclusion of Hydrocortisone in this formulation helps to alleviate the symptoms associated with these conditions.

Niacinamide, also known as Vitamin B3, has anti-inflammatory properties and can improve the skin's barrier function. It can also reduce the production of sebum, a type of oily substance that can lead to acne. Therefore, Niacinamide is beneficial in the treatment of acne and other inflammatory skin conditions.

Sulfur is a keratolytic agent, meaning it promotes the shedding of the top layer of skin. This helps to unclog pores and reduce inflammation, making it effective in treating acne, seborrheic dermatitis, and psoriasis. Sulfur also has antimicrobial properties, which can help to prevent the growth of bacteria on the skin.

This formulation is a versatile treatment option for a variety of skin conditions. It combines the antibacterial properties of Chloramphenicol, the anti-inflammatory and itch-relieving effects of Hydrocortisone, the sebum-reducing and barrier-enhancing effects of Niacinamide, and the keratolytic and antimicrobial properties of Sulfur. This makes it a comprehensive treatment option for conditions such as acne, dermatitis, eczema, psoriasis, and other bacterial skin infections.

As with any medication, it is important to use this cream as directed by your healthcare provider. If you have any questions about this formulation or how to use it, please reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to help.

Drug Interactions

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This formulation combines Chloramphenicol, Hydrocortisone, Niacinamide, and Sulfur in a topical cream designed for localized treatment. Each of these ingredients has a specific role in treating various skin conditions.

Chloramphenicol is a broad-spectrum antibiotic that is effective against a wide range of bacteria. It is used topically to treat bacterial infections of the skin. Hydrocortisone is a corticosteroid that reduces inflammation, itching, and redness. Niacinamide, a form of vitamin B3, has anti-inflammatory properties and can improve the skin's barrier function. Sulfur is used to treat acne and other skin disorders due to its keratolytic, antibacterial, and antifungal properties.

While this formulation is generally safe for most patients, there are potential drug interactions that prescribers and patients should be aware of. Chloramphenicol can interact with other antibiotics, potentially reducing their effectiveness. It can also interact with certain medications used to treat cancer, HIV, and seizures. If you are taking any of these medications, please inform your healthcare provider.

Hydrocortisone can interact with certain medications such as antifungals, antibiotics, and antivirals. It can also interact with certain vaccines, potentially reducing their effectiveness. If you are taking any of these medications or planning to receive a vaccine, please inform your healthcare provider.

Niacinamide can interact with certain medications such as anticoagulants and antiplatelet drugs, potentially increasing the risk of bleeding. It can also interact with certain diabetes medications, potentially affecting blood sugar control. If you are taking any of these medications, please inform your healthcare provider.

Sulfur can interact with certain topical medications such as benzoyl peroxide and salicylic acid, potentially causing skin irritation. If you are using any of these topical medications, please inform your healthcare provider.

It's important to note that this is not a complete list of potential drug interactions. Always inform your healthcare provider of all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us.

How Does it Work

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This topical cream is a combination of four active ingredients: Chloramphenicol, Hydrocortisone, Niacinamide, and Sulfur. Each of these ingredients plays a unique role in treating various skin conditions.

Chloramphenicol is a broad-spectrum antibiotic that works by inhibiting bacterial protein synthesis. It is effective against a wide range of bacteria, including those that cause skin infections. When applied topically, Chloramphenicol penetrates the skin and acts directly on the bacteria, killing them and preventing the spread of infection.

Hydrocortisone is a corticosteroid that works by reducing inflammation and immune responses. It helps to alleviate symptoms such as redness, swelling, itching, and discomfort caused by various skin conditions. Hydrocortisone achieves this by suppressing the body's immune response, thereby reducing inflammation and irritation.

Niacinamide, also known as Vitamin B3, has anti-inflammatory properties and helps to improve the skin's barrier function. It can help to reduce redness and swelling, improve skin texture, and hydrate the skin. Niacinamide also has the ability to reduce the production of sebum, a type of oil produced by the skin that can contribute to acne.

Sulfur is a keratolytic agent, meaning it works by causing the outer layer of the skin to shed. This helps to remove dead skin cells, unclog pores, and reduce the formation of blackheads and whiteheads. Sulfur also has antimicrobial properties and can help to kill bacteria on the skin's surface.

When combined in a topical cream, these four ingredients work together to treat a variety of skin conditions. The antibiotic properties of Chloramphenicol, the anti-inflammatory and immune-suppressing effects of Hydrocortisone, the skin barrier-enhancing and sebum-reducing abilities of Niacinamide, and the keratolytic and antimicrobial effects of Sulfur all contribute to the overall effectiveness of this formulation.

This cream is dispensed in a pump mechanism, which allows for convenient and controlled application. The semisolid preparation is designed to be easily absorbed by the skin, ensuring that the active ingredients can effectively treat the affected area.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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The Chloramphenicol 1%/Hydrocortisone 0.5%/Niacinamide 3%/Sulfur 7.8% Topical Cream formulation has a diverse range of potential uses beyond those commonly treated by each active ingredient individually. This unique blend of ingredients can be utilized for various conditions and ailments, depending on the patient's individual needs and circumstances. The following information is aimed at both patients and prescribers considering using this formulation for a broader range of skin conditions.

Chloramphenicol has powerful antibiotic properties and is often used to treat serious bacterial infections that are not responsive to other treatments. In a topical cream, it may aid in treating bacterial skin infections. Meanwhile, Hydrocortisone is a popular anti-inflammatory and is frequently used to aid in reducing swelling, itching, and redness associated with a range of skin conditions.

Niacinamide (Vitamin B3) has a wide array of skincare benefits. It enhances the appearance of dry or damaged skin by reducing flaking and restoring suppleness. Used in combination with other ingredients in the formulation, Niacinamide may contribute to overall skin health while improving the appearance and texture of the skin. Sulfur has been used for centuries to treat various skin conditions, including acne, seborrheic dermatitis, scabies, and rosacea. It is a useful ingredient in managing oily skin or clogged pores.

As a result, this formulated topical cream may be an effective treatment option for skin problems such as mild to moderate acne, rosacea, contact dermatitis, seborrheic dermatitis, and bacterial skin infections that are unresponsive to other antibiotic treatments. With its combined properties, it may also be beneficial for reducing inflammation and improving overall skin health and complexion. However, it's important for prescribers to consider and evaluate the patient's overall health status, concurrent medications, and potential for allergic reactions before prescribing this formulation.

If you have any further questions or need more information regarding the potential uses of the Chloramphenicol 1%/Hydrocortisone 0.5%/Niacinamide 3%/Sulfur 7.8% Topical Cream, please do not hesitate to reach out to us at Bayview Pharmacy. We are a knowledgeable team of compounding pharmacists and we are always more than willing to provide the information necessary to make informed decisions about your health care needs.

Frequently Asked Questions

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What is the purpose of this topical cream?

This cream is designed to deliver a localized treatment to the skin. Its active ingredients offer varied benefits, such as fighting bacterial infections (Chloramphenicol), reducing inflammation and itching (Hydrocortisone), maintaining skin health (Niacinamide), and treating skin conditions like acne and seborrheic dermatitis (Sulfur).

How should I apply this cream?

The cream is dispensed via a pump mechanism for an easy and controlled application. Apply a thin layer on the affected skin area as directed by your healthcare provider. Avoid contact with your eyes, nose, or mouth.

How often should I use this cream?

The frequency depends on the instructions given by your healthcare provider. Follow their advice closely and do not exceed recommended dosages to avoid potential side effects.

Can I apply this cream to open wounds or broken skin?

No, you should avoid applying to open wounds, cuts, or broken skin as it could potentially cause more harm. Ensure the area of application is clean and dry.

What side effects can this cream cause?

Some common side effects may include skin irritation, redness, burning, dryness, or peeling. Get medical help immediately if you notice any signs of a serious allergic reaction, such as a rash, itching/swelling, severe dizziness, or trouble breathing.

Do I need a prescription to access this cream?

Yes, this compounded formulation is generally prescribed by a healthcare provider based on the specific skin condition being treated.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you can. If it is nearly time for your next dose, just apply that dose. Do not apply extra to make up for a missed dose.

Can I use this cream while pregnant or breastfeeding?

When it comes to using this cream during pregnancy or breastfeeding, it is crucial to seek advice from your healthcare professional. They will determine if the benefits outweigh the risks based on your condition.

How should I store this cream?

Store this cream at room temperature, away from direct light and moisture. Keep the container tightly closed when not in use, and keep it out of the reach of children.

Can I use other skin products while using this cream?

Before using other skincare products, consult with your healthcare provider. They can provide information on whether the cream is compatible with other products you might be using.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.