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Carbidopa 25 mg/5 mL/Levodopa 250 mg/5 mL Oral Liquid

This formulation is a specially prepared oral liquid medication containing Carbidopa (25 mg/5 mL) and Levodopa (250 mg/5 mL). It is designed to provide a precise dosage of medication in a form that is easy to ingest, making it particularly suitable for individuals who find swallowing solid dosage forms difficult, as well as for pediatric and geriatric populations.

The Carbidopa/Levodopa oral liquid is primarily used to treat Parkinson's disease and Parkinson's-like symptoms that are associated with certain conditions. The combination of Carbidopa and Levodopa helps to control these symptoms by restoring the balance of chemicals in the brain. This formulation is also used to treat syndrome of the short gut (or short bowel syndrome) and is often used when conventional therapies have failed to manage these disease states effectively.

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Carbidopa
Levodopa
Oral Liquid
653847bc5090abb1df5f721b
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Formula Information

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This formulation of Carbidopa 25 mg/5 mL/Levodopa 250 mg/5 mL Oral Liquid is a specially designed medication for oral administration. It provides a convenient and easily ingested dosage form for accurate delivery of medication. This formulation is often used when swallowing solid dosage forms is challenging, such as in pediatric and geriatric populations, or for patients with dysphagia.

Carbidopa and Levodopa are two active ingredients in this formulation. Levodopa is converted into dopamine in the brain, helping to control the symptoms of Parkinson's disease, such as tremors, stiffness, and difficulty with movement. Carbidopa, on the other hand, prevents the breakdown of Levodopa in the body, allowing more Levodopa to reach the brain and improve its effectiveness.

This formulation is primarily used to treat Parkinson's disease and Parkinson's-like symptoms that may occur due to certain conditions (such as shingles, drug use, or brain injury). It is also used to manage symptoms of Parkinsonism, including poor muscle control, tremors, stiffness, and slow movement. The liquid form of this medication allows for precise dosing and is particularly beneficial for patients who have difficulty swallowing pills.

It's important to note that while this medication helps manage symptoms, it does not cure Parkinson's disease. Regular monitoring by a healthcare provider is necessary to adjust the dosage and manage any potential side effects, which may include nausea, vomiting, loss of appetite, and lightheadedness. Patients are advised to take this medication as directed by their healthcare provider and not to stop taking it abruptly without consulting their provider.

For prescribers, it's crucial to consider the patient's overall health status, other medications, and potential drug interactions when prescribing this formulation. Regular follow-ups are necessary to monitor the patient's response to the medication and adjust the dosage if needed.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide you with the information you need to make informed decisions about your healthcare.

Drug Interactions

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Carbidopa and Levodopa oral liquid is a combination medication used to treat symptoms of Parkinson's disease or Parkinson-like symptoms such as shakiness, stiffness, and difficulty moving. Parkinson's disease is thought to be caused by too little dopamine in the brain. Levodopa changes into dopamine in the brain, helping to control movement. Carbidopa can prevent the breakdown of levodopa in the bloodstream so more levodopa can enter the brain. Carbidopa can also reduce some of levodopa's side effects such as nausea and vomiting.

While Carbidopa/Levodopa oral liquid is a highly effective treatment, it may interact with other medications, potentially altering their effects and increasing the risk of adverse reactions. It is important to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter products, and dietary supplements.

Carbidopa/Levodopa oral liquid may interact with certain antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants. These interactions may increase the risk of serotonin syndrome, a potentially life-threatening condition. Symptoms of serotonin syndrome may include agitation, hallucinations, rapid heartbeat, fever, excessive sweating, shivering or shaking, muscle twitching or stiffness, trouble with coordination, and/or gastrointestinal problems.

Other medications that may interact with Carbidopa/Levodopa include certain antipsychotics, such as chlorpromazine and haloperidol, which may reduce the effectiveness of Carbidopa/Levodopa. Certain anti-seizure drugs, such as phenytoin, may also interact with Carbidopa/Levodopa, potentially increasing the risk of side effects.

Carbidopa/Levodopa oral liquid may also interact with certain high blood pressure medications, such as metoprolol, potentially leading to increased blood pressure. Certain anti-nausea medications, such as metoclopramide, may also interact with Carbidopa/Levodopa, potentially increasing the risk of side effects.

It is also important to note that Carbidopa/Levodopa oral liquid may interact with certain foods. For example, high-protein diets may reduce the absorption of levodopa, which may reduce the effectiveness of the medication. Therefore, it is recommended to evenly distribute protein intake throughout the day and to take this medication 30 minutes before or 1 hour after meals.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. If you have any questions about Carbidopa/Levodopa oral liquid or its potential interactions, please do not hesitate to reach out to us at Bayview Pharmacy. We are here to help.

How Does it Work

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Carbidopa and Levodopa oral liquid is a specially formulated medication that combines two active ingredients, Carbidopa and Levodopa, to treat symptoms of Parkinson's disease and Parkinson's-like symptoms such as shakiness, stiffness, and difficulty moving. This formulation is designed to be taken orally and is particularly useful for patients who have difficulty swallowing solid dosage forms.

Levodopa is converted to dopamine in the brain, which helps to control movement. However, when taken orally, a significant amount of Levodopa is broken down in the body before it reaches the brain. This is where Carbidopa comes in. Carbidopa is included in this formulation to prevent the breakdown of Levodopa before it reaches the brain, allowing for a lower dose of Levodopa to be used, which reduces side effects and increases the effectiveness of the medication.

The liquid formulation allows for precise dosing and is easily ingested, making it an excellent choice for pediatric and geriatric populations, or anyone who has difficulty swallowing pills. The liquid form also allows for the medication to be absorbed more quickly into the bloodstream, providing faster relief of symptoms.

It's important to note that while Carbidopa/Levodopa oral liquid can help manage symptoms of Parkinson's disease, it does not cure the disease. It is typically used in conjunction with other treatments as part of a comprehensive treatment plan. As with any medication, it's important to take it as directed by your healthcare provider and to communicate any side effects or concerns you may have.

If you have any questions about this formulation or how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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Carbidopa 25 mg/5 mL/Levodopa 250 mg/5 mL oral liquid formulation is typically used and known for treating motor symptoms of Parkinson's disease, a neurodegenerative disorder characterized by deteriorating motor skills, tremors, stiffness, and balance problems. This formulation combines two drugs: levodopa, which is the standard treatment for Parkinson's, and carbidopa, which prevents the breakdown of levodopa in the bloodstream, allowing it to be more effective.

Beyond the primary indication, the Carbidopa/Levodopa oral liquid formulation can be utilized off-label for other conditions characterized by motor function impairments. Secondary dystonia, a movement disorder marked by involuntary muscle contractions causing twisting and repetitive movements or abnormal postures, can be treated off-label with this formulation. Similarly, Restless Legs Syndrome (RLS), a neurological disorder causing an irresistible urge to move the legs, is another off-label condition this medication has been used for, particularly when other therapies have failed.

In addition to treating movement disorders, this medication's liquid form allows for versatile use in patients who struggle with swallowing solid dosage forms, such as tablets or capsules. This is particularly useful for pediatric patients, geriatric patients, and others dealing with dysphagia (difficulty swallowing). Furthermore, adjusting the dose can be easier for these patients by simply altering the liquid volume.

However, it is significantly crucial for healthcare providers to note that any use of Carbidopa/Levodopa oral liquid formulation outside of its conventional prescription requires careful consideration and oversight. Providers should weigh the potential benefits and risks, considering the onset, severity, and duration of symptoms, the patient's overall health status, and any possible interactions with other medications. As always, proper patient counseling about the potential side effects and reporting any serious or unexpected adverse events is key.

Please remember that any changes to a patient's medication regimen, including off-label use of drugs, should only be made under a healthcare provider's supervision, following a comprehensive clinical evaluation. For any questions or further discussion regarding the use of Carbidopa25 mg/5 mL/Levodopa 250 mg/5 mL oral liquid, do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to assist.

Frequently Asked Questions

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What is Carbidopa/Levodopa oral liquid?

Carbidopa/Levodopa oral liquid is a specifically formulated medication intended for oral administration. It provides a convenient and easily ingested dosage form for accurate delivery of medication. It is often used when swallowing solid dosage forms is challenging or for pediatric and geriatric populations.

Who is this medication typically for?

This type of medication is often used for individuals who have trouble swallowing solid dosages, such as children or the elderly, but can be used by anyone needing the medication.

What are the active ingredients in this compounded formulation?

The active ingredients in this compounded formulation are Carbidopa and Levodopa.

What are the dosages of these active ingredients per unit?

The dosage per 5mL unit includes 25mg of Carbidopa and 250mg of Levodopa.

Why is this drug administered in liquid form?

The liquid form provides an easy and accurate way to administer the medication, especially for those who have difficulty swallowing solid dosage forms. It is also quicker to be absorbed into the bloodstream.

Can this medication be taken with food?

Generally, it's possible to take this medication with food. However, it is best to consult your healthcare provider and follow their advice as the effectiveness and absorption of the drug can be affected by food.

Can this medication be used by all age groups?

Yes, this medication can be used by all age groups, including pediatric and geriatric populations, as long as they have been prescribed by a healthcare professional.

What kind of diseases or conditions is this medication used to treat?

The Carbidopa/Levodopa oral liquid formulation is mainly used to treat Parkinson's disease and Parkinson's-like symptoms. However, it could potentially be used for other conditions with off-label use. Always consult with your healthcare provider.

What are the storage guidelines for this medication?

The medication should be stored in a cool, dry place away from sunlight and kept out of children's reach. The storage instructions specific to this medication will be provided by the healthcare provider or pharmacist.

What shall I do if I miss a dose?

If a dose is missed, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Never take extra doses. However, always double-check with your healthcare provider.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.