This compounded topical gel combines Capsaicin 7.5 mg/mL, Ketamine HCl 20 mg/mL, and Ketoprofen 100 mg/mL in a semisolid formulation. Dispensed through a pump mechanism, it facilitates easy and precise application on the skin, ensuring targeted delivery of the active ingredients with a gel-like consistency.

Capsaicin, derived from chili peppers, is known for its analgesic properties. It works by desensitizing peripheral nociceptors and reducing the levels of substance P, a neuropeptide associated with pain transmission. This action can help alleviate discomfort in conditions involving neuropathic pain.

Ketamine HCl acts as an N-methyl-D-aspartate (NMDA) receptor antagonist. When applied topically, it may interrupt pain signaling pathways by blocking NMDA receptors in the peripheral nerves, contributing to analgesia without significant systemic effects.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes COX-1 and COX-2, reducing the synthesis of prostaglandins responsible for inflammation and pain. Its topical application targets the affected area directly, minimizing systemic exposure and potential side effects associated with oral NSAIDs.

This combination gel is formulated to manage localized pain conditions such as neuropathic pain, musculoskeletal pain, arthritis, and other inflammatory disorders. By integrating agents that address different pain pathways, the gel offers a multimodal approach to pain relief.

The pump mechanism ensures accurate dosing and ease of use. Patients should apply the prescribed amount of gel to the affected area as directed by their healthcare provider. It is important to avoid contact with eyes, mucous membranes, and broken skin. Hands should be washed

This topical gel formulation, containing Capsaicin 7.5 mg/mL, Ketamine HCl 20 mg/mL, and Ketoprofen 100 mg/mL, is designed for targeted treatment of pain and inflammation. It is important to consider potential drug interactions when using this formulation to ensure safety and efficacy. Capsaicin, a compound derived from chili peppers, is primarily used for its analgesic properties. It works by depleting substance P, a neuropeptide involved in transmitting pain signals. While topical capsaicin is generally considered safe, it may interact with other medications that affect nerve function or pain perception, such as certain antidepressants or anticonvulsants. Patients should inform their healthcare provider of all medications they are currently taking to avoid potential interactions.

Ketamine HCl, an NMDA receptor antagonist, is included in this formulation for its analgesic and anesthetic properties. Although primarily used in anesthesia, ketamine can also be effective in managing chronic pain when applied topically. However, ketamine may interact with other central nervous system (CNS) depressants, such as benzodiazepines, opioids, or alcohol, potentially leading to enhanced sedative effects. Patients should be advised to avoid or limit the use of other CNS depressants while using this gel to prevent excessive sedation or respiratory depression.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), is included for its ability to reduce inflammation and pain. Topical application of ketoprofen minimizes systemic exposure, but there is still a potential for interaction with other NSAIDs or anticoagulants, which could increase the risk of gastrointestinal bleeding or other adverse effects. Patients should be cautioned against using other NSAID-containing products concurrently and should inform their healthcare provider if they are taking blood thinners or have a history of gastrointestinal issues.

Overall, while the topical application of this gel reduces the likelihood of systemic drug interactions, it is crucial for both patients and prescribers to be aware of the potential interactions with other medications, especially those affecting the CNS or having anticoagulant properties. Patients should be encouraged to discuss their full medication regimen with their healthcare provider to ensure safe use of this formulation. If you have any questions or concerns about potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

This topical gel formulation combines three active ingredients: Capsaicin, Ketamine HCl, and Ketoprofen, each contributing to its therapeutic effects. The semisolid gel is dispensed through a pump mechanism, ensuring easy and precise application on the skin, which is crucial for targeted treatment and optimal absorption of the active ingredients.

Capsaicin, derived from chili peppers, works by desensitizing sensory neurons and reducing the sensation of pain. It achieves this by depleting substance P, a neuropeptide involved in transmitting pain signals to the brain. When applied topically, capsaicin can provide relief from chronic pain conditions by diminishing the intensity of pain signals in the affected area.

Ketamine HCl is an NMDA receptor antagonist that has been shown to have analgesic properties. In this topical formulation, ketamine works by blocking the NMDA receptors in the peripheral nervous system, which are involved in the transmission of pain signals. This action helps in reducing pain perception and can be particularly beneficial for neuropathic pain conditions, where traditional pain medications may not be as effective.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, which are chemicals in the body responsible for inflammation, pain, and fever. By reducing the levels of prostaglandins, ketoprofen helps to alleviate inflammation and pain in the affected area. Its inclusion in the gel formulation allows for localized anti-inflammatory effects, minimizing systemic exposure and potential side effects associated with oral NSAIDs.

The gel-like consistency of this formulation ensures that the active ingredients are delivered directly to the site of pain or inflammation, allowing for rapid absorption and onset of action. The pump mechanism facilitates precise dosing, ensuring that patients receive the correct amount of medication with each application. This targeted approach not only enhances the efficacy of the treatment but also reduces the risk of systemic side effects.

This combination of capsaicin, ketamine, and ketoprofen in a topical gel is designed to provide comprehensive pain relief by addressing multiple pathways involved in pain and inflammation. It is particularly useful for patients suffering from chronic pain conditions, such as neuropathic pain, arthritis, or localized musculoskeletal pain, where traditional oral medications may not provide adequate relief or may cause undesirable side effects.

If you have any questions about this formulation or its use, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have.

The Capsaicin 7.5 mg/mL/Ketamine HCl 20 mg/mL/Ketoprofen 100 mg/mL Topical Gel is primarily formulated for the management of pain and inflammation associated with various conditions. However, beyond its primary indications, this formulation may have other potential uses that could be beneficial for both patients and prescribers seeking alternative therapeutic options. The combination of capsaicin, ketamine, and ketoprofen in a topical gel form allows for localized treatment, which can be advantageous in managing conditions that require targeted therapy.

Capsaicin, a compound derived from chili peppers, is known for its ability to desensitize sensory neurons, which can be useful in managing neuropathic pain conditions. This property may make the gel beneficial for patients experiencing post-herpetic neuralgia, diabetic neuropathy, or other forms of nerve pain that are not adequately controlled by oral medications. Additionally, capsaicin's ability to reduce substance P, a neuropeptide associated with pain transmission, can be advantageous in chronic pain management.

Ketamine, an NMDA receptor antagonist, is recognized for its analgesic properties, particularly in cases of complex regional pain syndrome (CRPS) and other chronic pain syndromes that are resistant to conventional treatments. The topical application of ketamine can provide pain relief without the systemic side effects associated with oral or intravenous administration, making it a valuable option for patients who require long-term pain management.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), contributes to the anti-inflammatory and analgesic effects of the formulation. Its inclusion in the gel can be particularly useful for patients with localized inflammatory conditions such as tendinitis, bursitis, or osteoarthritis. The topical delivery of ketoprofen allows for high local concentrations at the site of application, potentially reducing systemic exposure and minimizing the risk of gastrointestinal side effects commonly associated with oral NSAIDs.

For prescribers, this formulation offers a versatile tool in the management of various pain and inflammatory conditions, especially when traditional therapies have proven inadequate or when patients are unable to tolerate systemic medications. The pump mechanism of the gel ensures precise dosing and ease of application, enhancing patient compliance and treatment outcomes. Patients seeking alternative or adjunctive therapies for their pain management may find this formulation particularly beneficial due to its targeted action and reduced systemic side effects.

If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or specific patient needs you may have.