This compounded capsule combines Caffeine Citrate 65 mg, Ketoprofen 25 mg, and Riboflavin 100 mg, offering a synergistic approach to managing conditions that benefit from enhanced analgesic effects, anti-inflammatory properties, and mitochondrial support. Encapsulated within gelatin or vegetarian shells, this solid dosage form provides precise dosing and convenient administration for patients requiring these specific active ingredients.

Caffeine Citrate acts as a central nervous system stimulant, known for increasing alertness and reducing fatigue. In this formulation, caffeine enhances the analgesic effects of ketoprofen and may improve the absorption and efficacy of the medication. Its vasoconstrictive properties can be particularly beneficial in alleviating headaches, including migraines, by narrowing dilated blood vessels in the brain.

Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that offers potent analgesic and anti-inflammatory effects. It works by inhibiting the synthesis of prostaglandins through the cyclooxygenase (COX) pathways, thereby reducing inflammation, pain, and fever. Ketoprofen is effective in treating mild to moderate pain associated with various conditions such as musculoskeletal disorders, arthritis, and menstrual cramps.

Riboflavin, also known as Vitamin B2, is essential for energy production and cellular function. It plays a critical role in mitochondrial energy metabolism by serving as a precursor for flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), coenzymes involved in redox reactions. Riboflavin supplementation has been shown to reduce the frequency and severity of migraines, likely due to its role in enhancing mitochondrial energy efficiency in neural tissue.

The combination of these three agents addresses both the symptomatic relief and the underlying factors contributing to certain conditions like migraines. While ketoprofen and caffeine provide immediate relief from pain and inflammation, riboflavin supports long-term mitochondrial health, potentially reducing the occurrence of symptoms over time. This multifaceted approach can improve patient outcomes and quality of life.

For patients, this compounded medication simplifies therapy by consolidating multiple medications into a single capsule, improving adherence and convenience. The precise dosing afforded by compounding allows for personalized treatment plans tailored to individual needs, especially when standard dosages are insufficient or contraindicated.

Healthcare providers should monitor for potential side effects and interactions. Common adverse effects may include gastrointestinal irritation or ulceration from ketoprofen, jitteriness or insomnia from caffeine, and, although rare, allergic reactions to riboflavin. Caution is advised in patients with a history of peptic ulcers, cardiovascular disease, hypertension, or sensitivity to NSAIDs or caffeine.

It is important to assess the patient's full medical history, including current medications and supplements, to avoid possible drug interactions. Ketoprofen may increase the risk of bleeding when taken with anticoagulants or other NSAIDs. Caffeine

This formulation of Caffeine Citrate 65 mg, Ketoprofen 25 mg, and Riboflavin 100 mg in capsule form is designed to provide a synergistic effect for the management of certain conditions, potentially including pain relief, inflammation reduction, and energy enhancement. However, it is crucial to consider potential drug interactions that may arise from the combination of these active ingredients.

Caffeine Citrate, a central nervous system stimulant, can interact with various medications. It may enhance the effects of other stimulants, leading to increased heart rate, elevated blood pressure, and heightened anxiety. Patients taking monoamine oxidase inhibitors (MAOIs) should avoid caffeine due to the risk of hypertensive crisis. Additionally, caffeine can interfere with the metabolism of certain drugs, such as clozapine and lithium, potentially leading to increased serum levels and toxicity. It is also known to interact with anticoagulants like warfarin, possibly affecting their efficacy.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), can interact with other medications that affect bleeding risk, such as anticoagulants and antiplatelet agents, increasing the likelihood of gastrointestinal bleeding. Concurrent use with other NSAIDs or corticosteroids can exacerbate gastrointestinal side effects. Ketoprofen may also reduce the antihypertensive effects of certain blood pressure medications, including ACE inhibitors, angiotensin II receptor blockers, and beta-blockers. Additionally, it can increase the nephrotoxic effects of certain drugs like cyclosporine and tacrolimus.

Riboflavin, or vitamin B2, generally has a low potential for drug interactions. However, it may affect the absorption and efficacy of certain antibiotics, such as tetracyclines, when taken concurrently. Additionally, riboflavin can interact with some anticholinergic medications, potentially altering their absorption and effectiveness. While riboflavin is generally considered safe, it is important to monitor for any unexpected interactions, especially in patients taking multiple medications.

Patients and prescribers should be aware of these potential interactions and consider them when evaluating the suitability of this formulation for individual patients. It is essential to review the patient's current medication regimen, including over-the-counter drugs and supplements, to identify any possible interactions. If you have any questions or concerns about the use of this formulation, please reach out to us for further guidance and support.

The Caffeine Citrate 65 mg/Ketoprofen 25 mg/Riboflavin 100 mg capsules are designed to deliver a synergistic combination of active ingredients that target multiple pathways to provide relief and support for various conditions. This formulation is encapsulated in solid dosage forms, utilizing either gelatin or vegetarian shells, which ensures ease of swallowing and precise dosing. This method of delivery is particularly beneficial for patients who require consistent and accurate administration of their medication.

Caffeine Citrate, a central nervous system stimulant, is included in this formulation for its ability to enhance alertness and reduce fatigue. It works by blocking adenosine receptors in the brain, which prevents the onset of drowsiness and increases the release of neurotransmitters like dopamine and norepinephrine. This action not only helps in improving mental focus and energy levels but also has potential benefits in managing certain types of headaches, including migraines, by constricting dilated blood vessels in the brain.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), is incorporated for its potent anti-inflammatory and analgesic properties. It works by inhibiting the cyclooxygenase (COX) enzymes, which are responsible for the synthesis of prostaglandins, compounds that mediate inflammation, pain, and fever. By reducing the production of these inflammatory mediators, Ketoprofen effectively alleviates pain and swelling associated with conditions such as arthritis, musculoskeletal injuries, and other inflammatory disorders.

Riboflavin, also known as vitamin B2, plays a crucial role in cellular energy production and the maintenance of healthy tissues. It is a key component of the coenzymes FAD and FMN, which are involved in various metabolic pathways, including the breakdown of carbohydrates, fats, and proteins. Riboflavin is also known for its antioxidant properties, helping to protect cells from oxidative stress. In the context of this formulation, Riboflavin is particularly beneficial for its potential role in migraine prevention, as studies have suggested that it may help reduce the frequency and severity of migraine attacks by improving mitochondrial energy metabolism in brain cells.

The combination of these three active ingredients in a single capsule offers a multifaceted approach to managing conditions that involve pain, inflammation, and fatigue, while also providing nutritional support. This formulation is particularly advantageous for patients who may benefit from the combined effects of a stimulant, an anti-inflammatory agent, and a vitamin supplement, all in one convenient dosage form.

If you have any questions about this formulation or its use, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to make informed decisions about your health care.

The formulation of Caffeine Citrate 65 mg, Ketoprofen 25 mg, and Riboflavin 100 mg in capsule form offers a unique combination of active ingredients that may have potential uses beyond the primary indications. Caffeine Citrate, a central nervous system stimulant, is commonly used to treat apnea of prematurity in neonates, but its stimulating properties can also be beneficial in enhancing alertness and cognitive performance in adults. This can be particularly useful for individuals experiencing fatigue or needing increased concentration, such as shift workers or students during exam periods. Additionally, Caffeine Citrate may aid in the management of certain types of headaches, including migraines, due to its vasoconstrictive properties.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), is primarily used for its analgesic and anti-inflammatory effects in conditions such as arthritis. However, its ability to reduce inflammation and pain can be advantageous in managing other musculoskeletal conditions, such as tendinitis or bursitis, and in providing relief from menstrual cramps. The anti-inflammatory properties of Ketoprofen may also be beneficial in treating mild to moderate pain associated with dental procedures or minor injuries.

Riboflavin, also known as Vitamin B2, plays a crucial role in energy production and the metabolism of fats, drugs, and steroids. While it is essential for maintaining overall health, Riboflavin supplementation has been explored for its potential in reducing the frequency and severity of migraine headaches. Additionally, Riboflavin may support eye health and prevent cataracts, as well as contribute to maintaining healthy skin and mucous membranes.

When combined, these three active ingredients in a capsule form provide a convenient and precise dosage, potentially offering synergistic effects that could be beneficial in managing conditions involving pain, inflammation, and fatigue. However, it is important for both patients and prescribers to consider the individual components and their interactions, as well as any contraindications or potential side effects. As with any medication, it is crucial to consult with a healthcare professional before starting this formulation to ensure it is appropriate for the patient's specific needs and health status. If you have any questions or require further information, please reach out to us at Bayview Pharmacy.