This formulation combines Bupivacaine HCl 0.5% and Ketoprofen 10% in a transdermal gel. Bupivacaine HCl is a local anesthetic that works by blocking nerve impulses, thereby reducing pain sensation. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by inhibiting the production of prostaglandins, substances in the body that cause inflammation and pain.

The gel is dispensed through a pump mechanism, which allows for easy and precise application on the skin. This targeted treatment ensures that the active ingredients are absorbed directly into the affected area, providing localized relief from pain and inflammation. The gel-like consistency also ensures that the medication stays in place, reducing the risk of the medication spreading to unaffected areas.

This formulation is particularly useful in treating various disease states that involve pain and inflammation. These include conditions such as arthritis, bursitis, and tendonitis. It can also be used to manage pain following surgical procedures or injuries. The combination of Bupivacaine HCl and Ketoprofen provides both immediate and long-lasting relief from pain and inflammation.

Patients using this formulation should apply it as directed by their healthcare provider. It is important to avoid applying the gel to broken or irritated skin, and it should not be used in conjunction with heat pads or other heating devices, as this could increase the absorption of the medication, potentially leading to unwanted side effects.

Prescribers should consider the patient's overall health status, other medications being taken, and the specific disease state being treated when deciding on the appropriate dose and frequency of application. As with all medications, the lowest effective dose for the shortest duration should be used to minimize the risk of side effects.

If you have any questions about this formulation, please do not hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.

Bupivacaine HCl 0.5%/Ketoprofen 10% Transdermal Gel is a unique formulation designed to provide targeted pain relief. Bupivacaine HCl is a local anesthetic that works by blocking nerve signals in your body, while Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. Together, they provide a potent combination for managing pain and inflammation.

However, like all medications, this formulation can interact with other drugs, potentially altering their effects or increasing the risk of side effects. It's crucial to inform your healthcare provider about all the medications you're currently taking, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements.

Specifically, Bupivacaine HCl may interact with certain medications such as other local anesthetics, antiarrhythmics (like amiodarone, mexiletine), cimetidine, and certain beta blockers (like metoprolol). These interactions can affect how Bupivacaine HCl works or increase the risk of serious side effects.

Ketoprofen, on the other hand, can interact with drugs such as aspirin, clopidogrel, corticosteroids (like prednisone), certain blood pressure medications (like ACE inhibitors, ARBs), and other NSAIDs (like ibuprofen, naproxen). These interactions can increase the risk of bleeding or kidney problems, or interfere with the effectiveness of the medications.

Furthermore, this formulation should not be used with other topical products, including creams, lotions, or gels, as they may alter the absorption of Bupivacaine HCl and Ketoprofen, potentially leading to increased side effects.

It's also important to note that alcohol and certain foods may interact with this formulation. Alcohol can increase the risk of stomach bleeding, while certain foods (like grapefruit) can affect the absorption of the medication. Always discuss your diet and alcohol consumption with your healthcare provider when starting a new medication.

Lastly, this formulation may interact with certain medical conditions. For instance, patients with a history of kidney disease, liver disease, stomach/intestinal problems (like bleeding, ulcers), heart disease (like previous heart attack), high blood pressure, stroke, blood disorders (like anemia), asthma, nasal polyps, or certain allergies (like aspirin/NSAID allergy) should use this medication cautiously.

Remember, this is not a complete list of possible drug interactions. Always consult your healthcare provider to ensure the safe and effective use of this medication. If you have any questions or concerns, don't hesitate to reach out to us at Bayview Pharmacy. We're here to help!

The Bupivacaine HCl 0.5%/Ketoprofen 10% Transdermal Gel is a unique formulation that combines the analgesic and anti-inflammatory properties of Bupivacaine and Ketoprofen, respectively. This formulation is designed to be applied topically, directly to the skin, where it is absorbed into the underlying tissues to provide targeted pain relief and inflammation reduction.

Bupivacaine HCl is a local anesthetic that works by blocking nerve impulses in your body, thereby reducing pain sensation. It is a long-acting anesthetic that provides prolonged pain relief. When applied topically, Bupivacaine HCl numbs the skin and surrounding tissues, reducing pain and discomfort in the treated area.

Ketoprofen, on the other hand, is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. When applied topically, Ketoprofen can reduce inflammation and pain in the specific area of application, without the systemic side effects associated with oral NSAIDs.

The gel formulation allows for easy and precise application of the medication. The active ingredients are suspended in a gel base that facilitates absorption through the skin and into the underlying tissues. The pump mechanism allows for controlled dispensing of the medication, ensuring that the correct dose is applied each time.

This formulation is particularly useful in treating localized pain and inflammation, such as that caused by osteoarthritis, rheumatoid arthritis, bursitis, and tendonitis. It can also be used to manage post-surgical pain or pain associated with injury. By applying the medication directly to the affected area, patients can achieve targeted relief without the systemic side effects associated with oral medications.

As with any medication, it is important to use Bupivacaine HCl 0.5%/Ketoprofen 10% Transdermal Gel as directed by your healthcare provider. Avoid contact with eyes, mucous membranes, or open wounds. If you experience any adverse reactions, discontinue use and contact your healthcare provider immediately.

If you have any questions about this formulation, or if you would like more information on how it can be used to manage your specific condition, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Bupivacaine HCl 0.5%/Ketoprofen 10% Transdermal Gel is primarily crafted to provide relief from localized pain by utilizing the anesthetic capabilities of Bupivacaine and the anti-inflammatory properties of Ketoprofen. However, this unique compounded preparation holds potential for other uses as well.

Given the inherent properties of Bupivacaine as a local anesthetic, this formulation could be used in the management of other conditions where local anesthesia is beneficial. For instance, it might be useful for temporary relief of pain associated with minor burns or sunburn. Furthermore, it could also be potentially applied to manage the discomfort associated with procedures such as tattooing or laser hair removal.

Ketoprofen, being a nonsteroidal anti-inflammatory drug (NSAID), could make this formulation useful for conditions associated with inflammation and swelling. There might be potential use in managing symptoms of conditions such as bursitis (inflammation of the bursae) and tendonitis (inflammation of a tendon). It could also be potentially beneficial for managing inflammation caused by insect bites or stings.

Given the transdermal form of the medication, it allows for targeted and controlled drug release which can be beneficial for managing chronic conditions requiring long term therapy. Further, this formulation may reduce systemic side effects seen with oral NSAIDs and could present an alternative option for patients with difficulties in swallowing or those with stomach ailments.

It's important for prescribers and patients to remember that while these potential uses exist, the primary indication, efficacy, and safety of Bupivacaine HCl 0.5%/Ketoprofen 10% Transdermal Gel is for local pain relief. Individual response and tolerance may vary and it is always advisable to first consult a healthcare provider before considering the use of this gel for other purposes. As compounding pharmacists, we are always ready to answer questions and provide detailed information regarding our formulations, so please do not hesitate to reach out to us.