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Budesonide 9 mg Rectal Suppository

The Budesonide 9 mg Rectal Suppository is a solid dosage form designed for insertion into the rectum. Upon insertion, the suppository dissolves or melts, releasing the medication for local or systemic absorption. Budesonide is a corticosteroid that reduces inflammation. This formulation is typically used to treat disease states such as inflammatory bowel diseases, including Crohn's disease and ulcerative colitis.

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Formula Information

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Budesonide 9 mg Rectal Suppository is a specialized formulation designed for targeted delivery of medication. As a solid dosage form, it is inserted into the rectum where it dissolves or melts, releasing the active ingredient, Budesonide, for local or systemic absorption. This method of administration is particularly beneficial for conditions that affect the lower gastrointestinal tract, as it allows for direct application of the medication to the affected area.

Budesonide is a corticosteroid that works by reducing inflammation in the body. It is commonly used in the treatment of various disease states such as Crohn's disease, ulcerative colitis, and other inflammatory bowel diseases. By delivering Budesonide directly to the rectum, this suppository formulation can provide targeted relief from the symptoms of these conditions, including pain, swelling, and discomfort.

For patients, it's important to understand that the use of Budesonide 9 mg Rectal Suppository should be under the guidance of a healthcare professional. The suppository should be inserted as directed by your healthcare provider, typically once or twice daily. It's also crucial to continue using the medication for the full course of treatment, even if symptoms improve, to ensure the best possible outcome.

For prescribers, it's worth noting that the Budesonide 9 mg Rectal Suppository offers a targeted treatment option for patients with lower gastrointestinal tract conditions. This formulation can be particularly beneficial for patients who have not responded well to oral medications or who have difficulty swallowing pills. However, as with all corticosteroids, it's important to monitor patients for potential side effects, including changes in mood or behavior, increased blood pressure, or signs of infection.

If you have any questions about the Budesonide 9 mg Rectal Suppository formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide the information and support you need.

Drug Interactions

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Budesonide is a corticosteroid that is used to treat a variety of conditions such as Crohn's disease, ulcerative colitis, and other inflammatory bowel diseases. It works by reducing inflammation in the body, which can help to alleviate symptoms such as pain, diarrhea, and bleeding.

While Budesonide is generally well-tolerated, it can interact with certain other medications. These interactions can alter the way Budesonide works or increase the risk of side effects. Therefore, it's important to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements.

One of the most significant drug interactions involves medications that can affect the breakdown of Budesonide in the body. These include certain antifungal medications (such as ketoconazole, itraconazole), certain antibiotics (such as clarithromycin, erythromycin), HIV protease inhibitors (such as ritonavir, atazanavir), and certain seizure medications (such as carbamazepine, phenytoin).

These medications can increase the level of Budesonide in the body, which can increase the risk of side effects. If you are taking any of these medications, your healthcare provider may need to adjust your dose of Budesonide or monitor you more closely for side effects.

Another significant interaction involves medications that can decrease the effectiveness of Budesonide. These include certain antacids (such as aluminum hydroxide, magnesium hydroxide), cholestyramine, and colestipol. If you are taking any of these medications, you may need to take them at a different time of day than Budesonide to prevent this interaction.

It's also important to note that Budesonide can interact with certain vaccines. Because Budesonide can weaken the immune system, it can reduce the effectiveness of certain vaccines or increase the risk of infection from live vaccines. Therefore, it's important to inform your healthcare provider if you are planning to receive any vaccines while taking Budesonide.

Lastly, Budesonide can interact with certain foods and beverages. Grapefruit and grapefruit juice can increase the level of Budesonide in the body, which can increase the risk of side effects. Therefore, it's recommended to avoid grapefruit and grapefruit juice while taking Budesonide.

This is not a complete list of all possible drug interactions. Therefore, it's important to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. If you have any questions about drug interactions with Budesonide, please reach out to us at Bayview Pharmacy.

How Does it Work

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Budesonide 9 mg Rectal Suppository is a solid dosage form that is inserted into the rectum, where it dissolves or melts to release the medication. Budesonide is a corticosteroid, a type of medication that reduces inflammation. It works by decreasing the body's immune response to reduce symptoms such as swelling and allergic-type reactions.

When the suppository is inserted into the rectum, the warmth of the body causes it to melt and the medication is then absorbed into the bloodstream through the rich supply of blood vessels found in this area. This allows the medication to act directly on the inflamed tissue in the rectum and lower part of the colon, which can be particularly beneficial for conditions such as ulcerative colitis and Crohn's disease.

By reducing inflammation in the rectum and lower colon, Budesonide can help to relieve symptoms such as pain, diarrhea, and bleeding. This can lead to an improvement in quality of life for patients suffering from these conditions. It is important to note that while Budesonide can help to manage symptoms, it is not a cure for these conditions and should be used as part of a comprehensive treatment plan under the guidance of a healthcare provider.

As with any medication, Budesonide may have side effects and it is important to discuss these with your healthcare provider before starting treatment. Common side effects can include nausea, heartburn, and headache. If you experience any unusual or severe side effects, you should contact your healthcare provider immediately.

If you have any questions about Budesonide 9 mg Rectal Suppository, or if you would like more information about how it works or how it can be used to treat certain conditions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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Budesonide 9 mg Rectal Suppositories are primarily indicated for the treatment of inflammatory bowel diseases, such as Ulcerative Colitis and Crohn’s disease, specifically for those conditions affecting the lower parts of the intestines and rectum. However, it is important to note that there may be alternative uses for this formulation, guided by a healthcare professional's discretion.

Aside from treating gastrointestinal conditions, Budesonide 9 mg Rectal Suppositories can also be used for conditions with underlying inflammation. It may potentially be useful for chronic inflammatory conditions affecting the rectum and anal canal, including proctitis and anal fissures. These conditions typically involve inflammation and can result in symptoms like pain, bleeding, and itching - symptoms which may be alleviated by the anti-inflammatory properties of Budesonide. Further research may be needed to verify these uses, and always consult a healthcare provider before use.

Lastly, the Budesonide Rectal Suppository, due to its local application and minimal systemic absorption, may be used off-label in various types of rectal or perianal issues when other treatments have failed and where the benefit outweighs the risks. However, all off-label applications should only be pursued upon thorough and detailed conversation with a healthcare provider, as every medication carries possible risks or side effects.

It's crucial to remember that all uses not mentioned in this document, aside from the primary indication, should only be performed under the proper guidance of a healthcare provider. Please, do not hesitate to reach out to us if you have any other questions or need further information about this formulation or its potential uses.

Frequently Asked Questions

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What is a Budesonide 9 mg Rectal Suppository?

A Budesonide 9 mg Rectal Suppository is a solid dose of medication that is inserted into the rectum. It dissolves or melts once inserted, releasing the medication both for local absorption in the rectum and systemic absorption throughout the body.

What is the function of a Budesonide 9 mg Rectal Suppository?

The primary function of the Budesonide 9 mg Rectal Suppository is to deliver a specific dose of the medication Budesonide to the body via rectal administration. This method of administration can treat local conditions in the rectum or provide systemic absorption of the medication throughout the body.

How is a Budesonide 9 mg Rectal Suppository administered?

The suppository is gently inserted into the rectum, where it will dissolve or melt to release the medication for absorption. For maximum effectiveness, it is advisable to follow your healthcare provider's specific instructions regarding administration.

Can the Budesonide 9mg Rectal Suppository be taken orally?

No, this formulation of Budesonide is designed expressly for rectal administration and should not be taken orally. Misuse can lead to unnecessary complications and diminished effectiveness of the medication.

What conditions are treated with Budesonide 9 mg Rectal Suppository?

The Budesonide 9 mg Rectal Suppository is commonly used to treat conditions that inflict the rectal area, such as Crohn's disease or ulcerative colitis. However, it may also be used in situations that warrant systemic absorption of its active ingredient, Budesonide.

What are the side effects of a Budesonide 9 mg Rectal Suppository?

Like all medications, Budesonide 9 mg Rectal Suppositories may have side effects. These can include local rectal discomfort, headache, nausea or changes in menstrual cycle. If you experience any side effects or adverse reactions, you should consult your healthcare provider immediately.

What should I do if I miss a dose of the Budesonide 9 mg Rectal Suppository?

If you miss a dose, take it as soon as you remember. However, if it is nearer the time for your next dose, skip the missed dose. Do not double the dosage to make up for a missed dose without consulting your healthcare provider.

How should the Budesonide 9 mg Rectal Suppository be stored?

Store this medication at room temperature, away from heat, moisture, and direct light. Always keep it out of reach of children and pets.

Can I use the Budesonide 9 mg Rectal Suppository if I have other medical conditions?

It’s vital to inform your healthcare provider of all the medical conditions that you have. This includes allergies, existing health problems like liver disease or osteoporosis, or if you're pregnant or breastfeeding. By doing so, your doctor will be able to make an informed decision on whether or not this treatment is suitable for you.

Can the Budesonide 9 mg Rectal Suppository interact with other medications?

Yes, this medication can interact with other drugs. Therefore, it's essential to let your healthcare provider know about all the medications you're taking, including prescription, over-the-counter, vitamin and herbal products to avoid potential drug interactions.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.