This formulation is a combination of Budesonide and Mesalamine, both of which are anti-inflammatory drugs, in a ready-to-use liquid enema form. The Budesonide 2 mg/60 mL/Mesalamine 1 g/60 mL Rectal Enema Liquid is contained in pre-filled enema bottles, designed for rectal administration. This provides a convenient and hygienic method for targeted treatment of constipation, bowel cleansing, or medication delivery. The formulation offers a measured dose of the solution for easy and controlled application without the need for additional preparation.

Budesonide is a corticosteroid that works by decreasing inflammation in the digestive tract, which can lead to improved symptoms of diseases like Crohn's disease and ulcerative colitis. Mesalamine, on the other hand, is an aminosalicylate anti-inflammatory drug. It works locally in the gut to reduce inflammation and can help to manage and prevent flare-ups of inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease.

The combination of these two drugs in an enema form allows for direct application to the rectum and lower part of the colon, which can be particularly beneficial for patients with proctitis or left-sided colitis. The formulation is designed to be easily administered at home, providing patients with a more comfortable and convenient treatment option.

It's important for patients to understand that while this formulation can help manage symptoms, it is not a cure for IBD or other inflammatory conditions of the digestive tract. Regular use as directed by a healthcare provider is necessary to maintain the benefits of the treatment. Side effects can include increased gas, stomach pain, and nausea. If these persist or worsen, patients should contact their healthcare provider immediately.

For prescribers, it's crucial to consider the patient's overall health status, other medications, and personal preferences when deciding to use this formulation. Regular monitoring of the patient's response to treatment is also necessary to ensure the medication is working effectively and to adjust the dose if needed.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Budesonide and Mesalamine are both anti-inflammatory drugs used to treat conditions such as ulcerative colitis and Crohn's disease. Budesonide works by decreasing inflammation in the digestive tract, while Mesalamine works by reducing the production of substances that cause inflammation in the body. This combination of drugs in a rectal enema form allows for targeted treatment, reducing inflammation and relieving symptoms such as diarrhea, rectal bleeding, and stomach pain.

However, like all medications, Budesonide and Mesalamine may interact with other drugs, potentially altering their effects or increasing the risk of side effects. It is important for patients and prescribers to be aware of these potential interactions.

Patients should inform their healthcare provider of all medications they are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. This is particularly important if the patient is taking any of the following: certain antibiotics (such as erythromycin, clarithromycin), antifungal medications (such as ketoconazole, itraconazole), or medications for HIV/AIDS (such as ritonavir, atazanavir).

These drugs may increase the levels of Budesonide in the body, potentially leading to increased side effects. On the other hand, certain medications such as carbamazepine, phenytoin, and rifampin may decrease the levels of Budesonide, potentially reducing its effectiveness.

For Mesalamine, potential drug interactions include azathioprine, 6-mercaptopurine, or other drugs that may harm the kidneys (including NSAIDs such as ibuprofen or naproxen). These drugs may increase the risk of kidney problems when taken with Mesalamine.

Furthermore, patients should avoid taking antacids or acid reducers (such as ranitidine, omeprazole) within a few hours of taking Mesalamine, as these medications can interfere with the absorption of Mesalamine.

It is also important to note that both Budesonide and Mesalamine may interact with live vaccines, potentially reducing the effectiveness of the vaccine. Patients should consult their healthcare provider before receiving any vaccines while using this medication.

Lastly, patients should avoid consuming grapefruit or grapefruit juice while using this medication, as grapefruit can increase the levels of Budesonide in the body, potentially leading to increased side effects.

This is not a complete list of potential drug interactions. Patients should always consult their healthcare provider or pharmacist for more information. If you have any questions, please do not hesitate to reach out to us at Bayview Pharmacy.

The Budesonide 2 mg/60 mL/Mesalamine 1 g/60 mL Rectal Enema Liquid is a combination medication that works by reducing inflammation in the gut and rectum. This formulation is designed to be administered rectally, providing a targeted treatment for conditions such as inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease.

Budesonide is a corticosteroid that works by decreasing inflammation. It does this by inhibiting the body's response to inflammation, reducing swelling, redness, and pain. This can help to alleviate the symptoms of IBD, such as abdominal pain, diarrhea, and rectal bleeding. Budesonide is particularly effective in the treatment of mild to moderate active Crohn's disease and ulcerative colitis, and for the maintenance of clinical remission in patients with Crohn's disease.

Mesalamine, on the other hand, is an anti-inflammatory drug. It works by blocking the production of certain natural chemicals in the body that may cause inflammation, thus reducing swelling and inflammation in the colon and rectum. Mesalamine is used to treat mild to moderate ulcerative colitis and to maintain remission in patients with this condition.

The combination of these two medications in a rectal enema liquid provides a targeted treatment for the inflammation associated with IBD. The rectal administration allows for the medication to be delivered directly to the site of inflammation, providing rapid relief from symptoms. The pre-filled enema bottles provide a convenient and hygienic method for medication delivery, with a measured dose of the solution for easy and controlled application.

It's important to note that while this medication can help manage the symptoms of IBD, it does not cure the disease. Regular use as directed by a healthcare provider is necessary to maintain the benefits of this medication. Side effects may include nausea, headache, and abdominal pain. If these persist or worsen, or if you experience any serious side effects such as chest pain or shortness of breath, seek medical attention immediately.

If you have any questions about this formulation, or if you need further information on how to use it, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

This formulation of Budesonide 2 mg/60 mL/Mesalamine 1 g/60 mL Rectal Enema Liquid is primarily utilized to treat gastrointestinal disorders such as Crohn's disease, Ulcerative Colitis, and to alleviate symptoms of inflammatory bowel diseases. Budesonide is a corticosteroid that reduces inflammation. Concurrently, Mesalamine also works as an anti-inflammatory agent in the bowels, promoting remission and preventing symptoms from recurring.

In addition to the primary uses, this formulation may also be employed as a symptomatic relief for diverticulitis, a condition marked by inflammation or small pouches in the diverticula wall of the digestive system, primarily in the lower parts of the large intestine. Due to its anti-inflammatory action, it helps to soothe the inflamed area and reduce symptoms associated with diverticulitis such as abdominal pain, fever and often changes in bowel habits.

The implementation of this formulation isn't limited to gastrointestinal disorders. It could also potentially be applied in the treatment of haemorrhoids. It's known that hemorrhoidal inflammation can result in swelling and discomfort. This composition, due to its anti-inflammatory properties, can assuage the inflammation and hence, mitigate the discomfort associated with haemorrhoids.

Furthermore, this formulation might help with rectal polyps since these are often the result of inflammation. Studies are currently being conducted to support this point, but preliminary reports suggest it could highlight another use for this formulation. It might also aid the tissue healing process.

Overall, while the primary use of this formulation is for gastro-intestinal disorders, its anti-inflammatory proprieties broaden its potential applications considerably. However, it's crucial for patients and prescribers to remember that these other uses haven't been completely verified and are largely dependent on the individual case. The formulation should always be used under professional advice and supervision. In case of any queries or for further information, please feel free to contact us at Bayview Pharmacy.