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Budesonide 1 mg/60 mL/Sodium Butyrate 100 mM Rectal Enema Liquid

This Budesonide 1 mg/60 mL/Sodium Butyrate 100 mM Rectal Enema Liquid is a ready-to-use formulation, conveniently contained in pre-filled enema bottles for rectal administration. It is designed to provide a hygienic and targeted treatment for various disease states, including constipation and bowel cleansing. This formulation also serves as a medication delivery system, offering a measured dose of the solution for easy and controlled application, eliminating the need for additional preparation.

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Enema
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Formula Information

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This formulation is a ready-to-use liquid solution of Budesonide 1 mg/60 mL/Sodium Butyrate 100 mM, contained in pre-filled enema bottles for rectal administration. Budesonide is a corticosteroid that reduces inflammation, while Sodium Butyrate is a short-chain fatty acid that promotes gut health and regular bowel movements. Together, they provide a targeted treatment for a variety of gastrointestinal conditions.

The formulation is designed to be convenient and hygienic, offering a measured dose of the solution for easy and controlled application. This eliminates the need for additional preparation, making it an ideal choice for patients who require regular treatment for their condition.

Budesonide is effective in treating a range of inflammatory bowel diseases, including Crohn's disease and ulcerative colitis. It works by reducing inflammation in the gut, which can help to relieve symptoms such as pain, diarrhea, and bleeding. Sodium Butyrate, on the other hand, is beneficial for maintaining gut health and promoting regular bowel movements. It can be used to treat constipation and to cleanse the bowel before medical procedures.

It's important for prescribers to note that while this formulation can provide significant relief for patients, it should be used as part of a comprehensive treatment plan that may include other medications, dietary changes, and lifestyle modifications. As with all medications, it's also crucial to monitor patients for potential side effects and to adjust the treatment plan as necessary.

Patients should be advised to use the enema as directed by their healthcare provider, and to seek medical attention if they experience any adverse reactions. They should also be reminded of the importance of regular follow-up appointments to monitor their condition and adjust their treatment plan as needed.

If you have any questions about this formulation, or if you need further information, please don't hesitate to reach out to us. We're here to help and provide the support you need to ensure the best possible treatment outcomes for your patients.

Drug Interactions

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Budesonide is a corticosteroid that reduces inflammation, while Sodium Butyrate is a short-chain fatty acid that promotes gut health and bowel regularity. This formulation is designed to treat conditions such as inflammatory bowel disease (IBD), Crohn's disease, ulcerative colitis, and constipation. It works by reducing inflammation in the gut and promoting regular bowel movements.

However, it's important to be aware of potential drug interactions. Budesonide can interact with a number of other medications, potentially altering their effects or increasing side effects. These include certain antibiotics (such as clarithromycin, erythromycin), antifungal medications (such as itraconazole, ketoconazole), and HIV protease inhibitors (such as ritonavir, atazanavir).

Additionally, Budesonide can interact with drugs that affect liver enzymes that remove budesonide from your body. These drugs include azole antifungals (such as ketoconazole), boceprevir, macrolide antibiotics (such as erythromycin), HIV protease inhibitors (such as ritonavir), telaprevir, among others. This can lead to increased levels of budesonide in the blood, increasing the risk of side effects.

Sodium Butyrate is generally considered safe and has fewer known drug interactions. However, it may interact with certain medications that affect the gut, such as other laxatives or antidiarrheal medications. It's important to tell your doctor about all medications you're currently taking, including over-the-counter drugs and supplements.

It's also important to note that both Budesonide and Sodium Butyrate can interact with certain foods. For example, grapefruit and grapefruit juice can increase the level of budesonide in your blood, potentially increasing side effects. It's generally recommended to avoid grapefruit while taking this medication.

Remember, this does not cover all possible drug interactions. Always consult with your healthcare provider or pharmacist to understand the potential interactions of this formulation with other substances. If you have any questions or concerns, don't hesitate to reach out to us at Bayview Pharmacy.

How Does it Work

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The Budesonide 1 mg/60 mL/Sodium Butyrate 100 mM Rectal Enema Liquid is a unique formulation that combines the anti-inflammatory properties of Budesonide with the beneficial effects of Sodium Butyrate on the gut microbiota. This formulation is designed to be administered rectally, providing a targeted approach to treating various disease states.

Budesonide is a corticosteroid that works by reducing inflammation in the body. It is often used to treat conditions such as Crohn's disease, ulcerative colitis, and other inflammatory bowel diseases. When administered rectally, Budesonide directly targets the inflamed areas of the colon and rectum, reducing inflammation and relieving symptoms such as pain, diarrhea, and bleeding.

Sodium Butyrate, on the other hand, is a short-chain fatty acid that is naturally produced by the gut microbiota during the fermentation of dietary fibers. It plays a crucial role in maintaining the health of the gut by providing energy for the cells lining the colon, enhancing the intestinal barrier function, and modulating the immune response. In addition, Sodium Butyrate has been shown to promote the growth of beneficial bacteria in the gut, which can help restore the balance of the gut microbiota in conditions such as inflammatory bowel disease and constipation.

Together, Budesonide and Sodium Butyrate work synergistically to reduce inflammation, restore the health of the gut microbiota, and relieve symptoms, providing a comprehensive approach to treating various disease states. The ready-to-use liquid formulation contained in pre-filled enema bottles ensures a convenient and hygienic method for medication delivery, offering a measured dose of the solution for easy and controlled application.

It's important to note that while this formulation can provide relief from symptoms, it is not a cure for the underlying disease. Therefore, it should be used as part of a comprehensive treatment plan under the guidance of a healthcare provider. As with any medication, it's important to use this formulation as directed by your healthcare provider and to report any side effects or concerns immediately.

If you have any questions about the Budesonide 1 mg/60 mL/Sodium Butyrate 100 mM Rectal Enema Liquid, please don't hesitate to reach out to us. We are here to provide you with the information and support you need to make informed decisions about your health.

Other Uses

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This formulation of Budesonide 1 mg/60 mL/Sodium Butyrate 100 mM Rectal Enema Liquid can also be utilized for other medical conditions aside from its primary uses in constipation and bowel cleansing. One of the crucial potential uses of this medication can be in dealing with gastrointestinal disorders such as inflammatory bowel syndrome (IBS) and Crohn's disease. It essentially aids in reducing inflammation in the intestinal tract, ultimately leading to relief from the symptoms associated with these conditions.

Furthermore, this medication may provide therapeutic benefits in colitis management. Colitis is an inflammatory bowel disease characterized by long-lasting inflammation and sores in the innermost lining of the colon and rectum. Through rectal administration, Budesonide and Sodium Butyrate can help reduce inflammation, promote healing within the bowel, and improve disease outcomes.

It's also vital to note that this medication can sometimes be used off-label for the treatment of other diseases at the discretion of a healthcare provider. Such off-label uses might include the management of select autoimmune disorders, other inflammatory diseases of the gastrointestinal tract, or certain infections that prompt inflammation within the gut. However, these applications should always be considered and supervised by a healthcare professional to ensure safety and effectiveness.

We encourage both patients and prescribers to reach out with any questions or concerns regarding the alternative uses of Budesonide 1 mg/60 mL/Sodium Butyrate 100 mM Rectal Enema Liquid. Our team of knowledgeable pharmacists at Bayview Pharmacy is always ready to assist with your pharmaceutical needs and inquiries.

Frequently Asked Questions

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What is this compounded formulation of Budesonide 1 mg/60 mL/Sodium Butyrate 100 mM Rectal Enema Liquid?

This is a ready-to-use liquid formulation contained in pre-filled enema bottles, designed specifically for rectal administration. It offers a measured dose of solution, eliminating the need for additional preparation.

What is the primary purpose of this medication?

The formulation is primarily used for targeted treatment of constipation, bowel cleansing, or medication delivery.

How is this medication administered?

This rectal enema liquid is administered rectally. The use of pre-filled enema bottles allows for a convenient, hygienic method for application.

What does a 'measured dose' mean?

A 'measured dose' signifies that each bottle contains a specific, pre-determined amount of the solution, providing for controlled and accurate application.

What should I do if I miss a dose?

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Continue your regular dosing schedule but do not double the dose to catch up.

How should I store this medication?

Store this medication at room temperature. Protect from heat, light, and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

What is Budesonide?

Budesonide is a steroid that reduces inflammation in the body. This medication may be used alone or with other medications to treat a variety of conditions.

What is Sodium Butyrate?

Sodium Butyrate is a compound that has been found to have beneficial effects on the gut and colon health, and is used in this medication.

Can I use this medication on my own?

The medication should only be used under the instruction and supervision of a healthcare professional. Self-medication is not advised.

What should I do in case of an overdose?

In case of an overdose, get medical help or contact a Poison Control Center right away. Overdose symptoms may include confusion, severe stomach pain, or bloody bowel movements.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.