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Formulas

Betamethasone Valerate 0.04%/Mupirocin 0.66%/Nystatin 33333 IU/g Topical Cream

This formulation is a semisolid preparation of Betamethasone Valerate 0.04%, Mupirocin 0.66%, and Nystatin 33333 IU/g, dispensed in a pump mechanism for convenient and controlled application. The cream is designed for localized treatment on the skin, facilitating the absorption of active ingredients.

Betamethasone Valerate is a potent corticosteroid that reduces inflammation, itching, and redness. Mupirocin is an antibiotic that prevents bacteria from growing on your skin. Nystatin is an antifungal medication that works by stopping the growth of fungus. Combined, these active ingredients effectively treat a variety of skin conditions including eczema, psoriasis, dermatitis, skin infections caused by bacteria, and skin infections caused by fungus.

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Betamethasone Valerate
Nystatin
Mupirocin Calcium
Topical Cream
65359dcdcd42260ace1088f7
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Formula Information

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This formulation is a compounded topical cream containing Betamethasone Valerate 0.04%, Mupirocin 0.66%, and Nystatin 33333 IU/g. It is dispensed in a pump mechanism for easy and controlled application on the skin. The cream is designed to deliver localized treatment, allowing for the absorption of the active ingredients directly at the site of the disease.

Betamethasone Valerate is a potent corticosteroid that works by reducing inflammation, redness, and itching. It is commonly used to treat a variety of skin conditions such as eczema, dermatitis, allergies, and rash. Mupirocin is an antibiotic that prevents bacteria from growing on your skin. It is used to treat certain types of skin infections such as impetigo and folliculitis. Nystatin is an antifungal medication that works by stopping the growth of fungus. It is used to treat skin infections caused by yeast.

This combination of medications in one cream provides a broad spectrum of treatment, addressing inflammation, bacterial infections, and fungal infections simultaneously. This can be particularly beneficial for patients with complex skin conditions, or those who have not responded to single-ingredient treatments.

As with any medication, it is important to use this cream as directed by your healthcare provider. Apply a thin layer to the affected area, usually twice daily or as directed by your doctor. Wash your hands before and after use. Do not cover, bandage, or wrap the area unless directed to do so by your doctor. If your condition does not improve after a few days or if it worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

Side effects may include burning, stinging, itching, or redness at the application site. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.

It is important to note that this is a compounded medication, meaning it is made specifically for you based on a prescription from your doctor. It is not a commercially available product, so it should be used only under the supervision of a healthcare provider who is familiar with your medical history and current health status.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help you understand your medication and how to use it effectively.

Drug Interactions

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This topical cream formulation combines three active ingredients: Betamethasone Valerate, Mupirocin, and Nystatin. Each of these ingredients has its own potential for drug interactions, which can be amplified when used in combination. It's important for patients and prescribers to be aware of these potential interactions to ensure safe and effective use of this medication.

Betamethasone Valerate is a potent corticosteroid that can suppress the immune response and reduce inflammation. It may interact with other medications that also suppress the immune system, such as cyclosporine, tacrolimus, or other corticosteroids. This could potentially increase the risk of infections or other side effects. Additionally, Betamethasone Valerate may decrease the effectiveness of vaccines and should not be used concurrently with live vaccines.

Mupirocin is an antibiotic that works by stopping the growth of certain bacteria. It has few known drug interactions, but it should not be used with other topical products that contain calcium, as calcium can bind to Mupirocin and decrease its effectiveness. Additionally, concurrent use of other topical antibiotics may increase the risk of developing antibiotic resistance.

Nystatin is an antifungal medication that works by stopping the growth of fungus. It may interact with other antifungal medications, potentially reducing their effectiveness. Additionally, Nystatin can interact with certain cholesterol-lowering drugs, such as lovastatin and simvastatin, increasing the risk of serious side effects like muscle pain and kidney problems.

This formulation is designed to treat a variety of skin conditions, including eczema, psoriasis, bacterial infections, and fungal infections. The combination of a corticosteroid, an antibiotic, and an antifungal allows it to target a wide range of pathogens and inflammatory processes. However, it's important to use this medication only as directed by a healthcare provider, as overuse or misuse can lead to increased side effects and decreased effectiveness.

If you have any questions about this medication or its potential interactions, please don't hesitate to reach out to us. We're here to help ensure that your treatment is safe and effective.

How Does it Work

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The topical cream formulation of Betamethasone Valerate 0.04%/Mupirocin 0.66%/Nystatin 33333 IU/g works by combining the therapeutic effects of three active ingredients: Betamethasone Valerate, Mupirocin, and Nystatin. Each of these ingredients plays a unique role in treating various skin conditions.

Betamethasone Valerate is a potent corticosteroid that works by reducing inflammation, redness, and itching. It does this by suppressing the immune response, which reduces the release of chemicals in the body that cause inflammation. This makes it effective in treating a variety of skin conditions that involve inflammation and itching, such as eczema and psoriasis.

Mupirocin is an antibiotic that works by stopping the growth of certain bacteria. It does this by inhibiting the synthesis of bacterial proteins, which are necessary for the bacteria to grow and multiply. This makes it effective in treating skin infections caused by certain types of bacteria.

Nystatin is an antifungal medication that works by stopping the growth of fungus. It does this by binding to sterols in the fungal cell membrane, which disrupts the membrane and causes leakage of cellular contents. This makes it effective in treating skin infections caused by certain types of fungus, such as Candida.

The semisolid preparation of this formulation is designed for convenient and controlled application on the skin. The pump mechanism allows for easy dispensing of the cream, and the semisolid form ensures that the active ingredients stay in contact with the skin for a sufficient amount of time to exert their therapeutic effects. This makes it effective in treating localized skin conditions.

It's important to note that this formulation should be used as directed by a healthcare provider, and it's not suitable for treating all types of skin conditions. It should not be used on the face, groin, or underarms unless directed to do so by your doctor. Also, it should not be used for longer than prescribed, as prolonged use can lead to side effects such as skin thinning and resistance to treatment.

If you have any questions about this formulation, or if you're unsure whether it's suitable for your condition, don't hesitate to reach out to us. We're here to help.

Other Uses

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Besides the intended disease states, the Betamethasone Valerate 0.04%/Mupirocin 0.66%/Nystatin 33333 IU/g Topical Cream formulation may be used for a range of other conditions. This medication combination is primarily regarded as an effective anti-inflammatory and antimicrobial treatment. Aside from its primary indication, this potent steroid cream is frequently utilized off-label to reduce inflammation and discomfort caused by various skin diseases such as eczema, dermatitis, and allergies.

The mupirocin component demonstrates strong antibacterial properties, capable of treating small superficial skin infections such as impetigo, folliculitis, and furunculosis. It could also be used prophylactically to prevent postoperative wound infections. Moreover, it is sometimes applied into the nostrils to eradicate Methicillin-Resistant Staphylococcus Aureus (MRSA) colonization, to reduce the risk of subsequent infections.

Nystatin, containing potent antifungal properties, can be used to manage a variety of fungal infections due to Candida species. This includes but is not limited to cutaneous candidiasis, moniliasis, diaper rash, and perianal infections. It is also potentially effective in treating Intertrigo, a form of dermatitis appearing in skin folds, common in overweight or diabetic individuals.

However, it should be explicitly pointed out that using this multiple-active-ingredient topical cream for off-label purposes should be base on a qualified healthcare professional's judgment. They should consider factors such as the patient's overall health status, the severity of the condition, potential side effects, and the potential risks versus benefits of treatment. Interaction with other drugs being used concurrently should also be taken into consideration. Remember to follow the pharmacists' or doctors' advice concerning the frequency and duration of application to ensure maximum efficacy while minimizing potential side effects.

If you have any further inquiries on using this formulation for other potential applications, please do not hesitate to reach out to us. We are committed to providing evidence-based information to guide healthcare decisions, ensure patient safety, and improve treatment outcomes.

Frequently Asked Questions

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What is this compounded formulation of the topical cream comprised of?

This topical cream contains a compounded formulation of Betamethasone Valerate 0.04%, Mupirocin 0.66%, and Nystatin 33333 IU/g.

What is the application method of this topical cream?

This cream is designed to be applied through a pump mechanism designed for controlled and convenient application on the skin.

What is the main purpose of this topical cream?

It's used for localized treatment and absorption of active ingredients on the skin.

What is the form of this topical cream?

This topical cream is a semisolid preparation, meaning it holds its shape at room temperature, but easily spreads or can be manipulated onto the skin using the body's heat.

Who can use this compounded formulation of topical cream?

Please consult your healthcare provider. This medication is typically prescribed under their direction following diagnosis of a specific skin condition that requires treatment with this specific formulation.

How often should this topical cream be applied?

The frequency and duration of application is dependent on the condition being treated, individual patient response, and the advice of the healthcare provider.

What precautions should I take while using this cream?

Always use this cream as directed by your healthcare provider, and avoid contact with eyes, nose, and mouth. If contact occurs, rinse immediately with plenty of water.

Can I use the cream on broken or damaged skin?

Please consult your healthcare provider before applying to affected areas. The cream is often intended for intact skin; application on broken or damaged skin may lead to more pronounced side effects.

What should I do if I experience any side-effects?

If you notice any side-effects, it’s important to report them to your healthcare provider promptly for guidance on next steps or potential adjustments to the treatment regimen.

What are the active ingredients in the cream and what do they do?

Active ingredients include Betamethasone Valerate, which is a steroid that reduces inflammation; Mupirocin, an antibiotic that prevents bacterial growth; and Nystatin, an antifungal agent used to treat fungal skin infections.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.