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Benzocaine 1%/Bismuth Subgallate 5%/Phenol 1.5%/Zinc Oxide 5% Rectal Ointment

This Benzocaine 1%/Bismuth Subgallate 5%/Phenol 1.5%/Zinc Oxide 5% Rectal Ointment is a semi-solid formulation dispensed in a tube, designed for external application to the skin. It features a greasy or oily base that facilitates the delivery of active ingredients for localized treatment.

This ointment is specifically formulated to provide relief from symptoms associated with hemorrhoids, anal fissures, and other rectal irritations. Benzocaine acts as a local anesthetic to alleviate pain, while Bismuth Subgallate and Zinc Oxide offer protective and astringent properties to reduce inflammation and promote healing. Phenol contributes antiseptic qualities to prevent infection.

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Topical Ointment
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Formula Information

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This compounded Benzocaine 1%/Bismuth Subgallate 5%/Phenol 1.5%/Zinc Oxide 5% Rectal Ointment is formulated to provide relief from symptoms associated with anorectal disorders such as hemorrhoids, anal fissures, and other localized inflammation or irritations in the rectal area. The ointment is dispensed in a semi-solid form within a tube, designed for external application to the skin around the anal region. Its greasy or oily base facilitates the delivery of the active ingredients directly to the affected area, promoting localized treatment and improving patient comfort.

Benzocaine at a concentration of 1% acts as a local anesthetic by inhibiting voltage-gated sodium channels on nerve membranes, thereby reducing nerve conduction and providing temporary relief from pain and discomfort. This helps alleviate the acute pain often associated with hemorrhoidal flare-ups or anal fissures, improving patient quality of life during healing.

Bismuth Subgallate 5% possesses astringent and mild antibacterial properties. It works by precipitating proteins on the surface of tissues, which leads to a protective coating over the affected area. This action reduces irritation, soothes inflamed tissues, and helps decrease secretions by constricting the mucous membranes. Additionally, its antibacterial effect minimizes the risk of secondary infections in the irritated area.

Phenol at a concentration of 1.5% serves as both an antiseptic and a local anesthetic. As an antiseptic, phenol denatures proteins and disrupts cell walls, effectively reducing microbial load and preventing infection. Its local anesthetic properties complement those of benzocaine, providing enhanced pain relief by further blocking nerve impulses in the area of application.

Zinc Oxide 5% is known for its skin-protective properties. It acts as a physical barrier, protecting irritated skin from external irritants and excessive moisture. Zinc oxide also has mild astringent and antiseptic qualities, promoting healing by reducing inflammation and inhibiting the growth of certain bacteria on the skin's surface.

When combined in this ointment, these ingredients work synergistically to provide comprehensive relief from pain, itching, inflammation, and irritation associated with anorectal conditions. The formulation not only addresses the immediate discomfort but also promotes healing of the affected tissues. The oily base enhances the absorption of the active ingredients and maintains prolonged contact with the skin, ensuring sustained therapeutic effects.

For patients, it is important to apply the ointment as directed by a healthcare professional, typically by applying a small amount to the affected area up to several times a day, especially after bowel movements and before bedtime. Patients should wash their hands before and after applying the ointment and avoid contact with eyes and mucous membranes other than the intended area. If symptoms persist or worsen, they should consult their healthcare provider.

Prescribers should consider this compounded ointment for patients who require a multi-faceted approach to managing anorectal discomfort, particularly when over-the-counter options are insufficient. The combination of analgesic, protective, astringent, and antiseptic components makes it a valuable option for individualized patient care. As with all compounded medications, prescribers should assess the patient's individual needs, potential allergies to components, and the suitability of the formulation for their specific condition.

If you have any questions, please reach out to us.

Drug Interactions

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This compounded rectal ointment formulation contains Benzocaine 1%, Bismuth Subgallate 5%, Phenol 1.5%, and Zinc Oxide 5%, each contributing to its therapeutic effects. Benzocaine is a local anesthetic that provides temporary relief from pain and discomfort by numbing the affected area. Bismuth Subgallate acts as an astringent, reducing inflammation and irritation. Phenol serves as an antiseptic and anesthetic, further aiding in pain relief and preventing infection. Zinc Oxide is known for its protective properties, forming a barrier on the skin to prevent irritation and promote healing. This combination is typically used for conditions such as hemorrhoids, anal fissures, and other forms of rectal discomfort.

When considering drug interactions, it is important to note that this formulation is intended for topical use and systemic absorption is minimal. However, interactions can still occur, particularly if the patient is using other topical medications or has specific sensitivities. Patients should inform their healthcare provider of all medications they are currently using, including over-the-counter drugs, supplements, and herbal products, to avoid potential interactions.

Benzocaine, as a local anesthetic, may interact with other medications that affect the central nervous system, potentially enhancing their effects. Caution is advised when used concurrently with other anesthetics or sedatives. Additionally, patients with a history of methemoglobinemia should use benzocaine-containing products with caution, as it may exacerbate this condition.

Phenol, due to its antiseptic properties, may interact with other topical agents that have similar effects, potentially leading to increased irritation or skin reactions. It is advisable to avoid using other phenol-containing products simultaneously unless directed by a healthcare provider.

Zinc Oxide is generally well-tolerated and has a low potential for interactions. However, it may affect the absorption of other topical medications if applied concurrently. Patients should be advised to apply other topical treatments at different times to avoid interference with the efficacy of this ointment.

While Bismuth Subgallate is primarily used for its astringent properties, it is important to monitor for any signs of allergic reactions or sensitivities, especially in patients with a known allergy to bismuth compounds. Patients should be advised to discontinue use and seek medical attention if they experience severe irritation, rash, or other adverse effects.

For prescribers, it is crucial to assess the patient's overall medication regimen and medical history to ensure the safe use of this compounded ointment. Consideration should be given to the patient's skin condition, potential allergies, and any concurrent medications that may interact with the active ingredients. Regular follow-up and monitoring are recommended to evaluate the treatment's effectiveness and address any concerns that may arise.

If you have any questions or require further information regarding this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have.

How Does it Work

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This rectal ointment formulation combines Benzocaine 1%, Bismuth Subgallate 5%, Phenol 1.5%, and Zinc Oxide 5% to provide a comprehensive treatment for conditions such as skin inflammation, infections, and wound healing. Each component plays a specific role in alleviating symptoms and promoting healing, making this ointment a versatile option for localized treatment.

Benzocaine, a local anesthetic, works by blocking nerve signals in the body, providing temporary relief from pain and discomfort. When applied to the affected area, it numbs the skin, reducing the sensation of pain and allowing for more comfortable healing. This is particularly beneficial for conditions that involve irritation or soreness, as it helps to alleviate the immediate discomfort associated with these symptoms.

Bismuth Subgallate is known for its astringent and protective properties. It works by forming a protective barrier over the affected area, which helps to reduce irritation and prevent further damage. This barrier also aids in reducing inflammation and controlling minor bleeding, which can be particularly useful in treating hemorrhoids or other rectal conditions. Additionally, Bismuth Subgallate has mild antimicrobial properties, which can help in preventing infections in compromised skin areas.

Phenol acts as an antiseptic and anesthetic, complementing the effects of Benzocaine. It helps to disinfect the area, reducing the risk of infection, while also providing additional pain relief. Phenol's antiseptic properties ensure that the ointment not only soothes but also protects the skin from potential bacterial contamination, which is crucial in maintaining a healthy healing environment.

Zinc Oxide is a well-known skin protectant that provides a physical barrier on the skin, shielding it from irritants and moisture. This is particularly important in rectal applications, where moisture and friction can exacerbate symptoms. Zinc Oxide also has anti-inflammatory properties, which help to reduce swelling and redness, promoting a more rapid healing process. Its ability to soothe and protect makes it an essential component in treating various skin conditions.

The semi-solid formulation of this ointment, dispensed in a tube, ensures ease of application and optimal adherence to the skin. The greasy or oily base not only facilitates the delivery of the active ingredients but also provides a moisturizing effect, which can be beneficial in preventing dryness and further irritation. This formulation is designed for external application, making it suitable for direct application to the affected area, ensuring that the active ingredients are delivered precisely where they are needed.

For both patients and prescribers, this combination of active ingredients offers a multi-faceted approach to treating skin inflammation, infections, and wound healing. By addressing pain, inflammation, infection, and protection, this ointment provides comprehensive care for a variety of conditions. If you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy. We are here to assist you with any inquiries you may have.

Other Uses

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The Benzocaine 1%/Bismuth Subgallate 5%/Phenol 1.5%/Zinc Oxide 5% Rectal Ointment is primarily formulated for the treatment of conditions such as skin inflammation, infections, or wound healing. However, this versatile formulation may have other potential uses that can be beneficial for both patients and prescribers to consider. The combination of active ingredients in this ointment provides a multifaceted approach to symptom relief and healing, which can be advantageous in managing a variety of other conditions.

Benzocaine, a local anesthetic, can be effective in providing temporary relief from pain and discomfort associated with minor skin irritations, burns, and insect bites. Its numbing effect can be particularly useful in alleviating the discomfort of hemorrhoids or anal fissures, making it a valuable component in rectal applications. Bismuth Subgallate, known for its astringent properties, can help reduce minor bleeding and protect irritated skin, which can be beneficial in managing symptoms of hemorrhoids or other anorectal disorders.

Phenol, with its antiseptic and anesthetic properties, can aid in reducing the risk of infection in minor cuts, scrapes, and burns, while also providing pain relief. This makes the ointment suitable for use in minor wound care, where both infection control and pain management are desired. Zinc Oxide, a well-known skin protectant, forms a barrier on the skin to protect against moisture and irritants, which can be particularly helpful in preventing diaper rash or treating mild skin irritations caused by incontinence.

In addition to these uses, the ointment's formulation in a greasy or oily base enhances its ability to provide a protective barrier, making it suitable for use in conditions where skin protection and moisture retention are important. This can include the management of dry, chapped skin or as a protective layer in areas prone to friction and irritation. The ointment's ability to soothe and protect the skin can also be beneficial in managing symptoms of eczema or psoriasis, where maintaining skin integrity and reducing irritation are key components of treatment.

While these additional uses highlight the versatility of the Benzocaine 1%/Bismuth Subgallate 5%/Phenol 1.5%/Zinc Oxide 5% Rectal Ointment, it is important for both patients and prescribers to consider individual patient needs and potential sensitivities to any of the active ingredients. As with any medication, it is advisable to consult with a healthcare professional before using the ointment for off-label purposes. If you have any questions or need further information, please reach out to us at Bayview Pharmacy.

Frequently Asked Questions

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What is Benzocaine 1%/Bismuth Subgallate 5%/Phenol 1.5%/Zinc Oxide 5% Rectal Ointment used for?

This compounded rectal ointment is typically used for the treatment of conditions such as skin inflammation, infections, or wound healing in the rectal area. It provides localized relief and aids in the healing process.

How should I apply this rectal ointment?

Apply a small amount of the ointment to the affected area as directed by your healthcare provider. Ensure the area is clean and dry before application. Wash your hands thoroughly after applying the ointment.

Can I use this ointment for other skin conditions?

This ointment is specifically formulated for rectal use. Consult your healthcare provider before using it for other skin conditions to ensure it is appropriate and safe for your specific needs.

Are there any side effects associated with this ointment?

Some users may experience mild irritation, redness, or a burning sensation at the application site. If you experience severe side effects or an allergic reaction, discontinue use and seek medical attention immediately.

How often should I apply the ointment?

Follow the instructions provided by your healthcare provider. Typically, the ointment is applied 2-3 times daily or as needed for symptom relief. Do not exceed the recommended dosage.

Is this ointment safe for children?

Consult a healthcare provider before using this ointment on children. The safety and efficacy for pediatric use should be determined by a medical professional.

Can I use this ointment if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, consult your healthcare provider before using this ointment to ensure it is safe for you and your baby.

How should I store this ointment?

Store the ointment at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not apply extra ointment to make up for a missed dose.

Can I use other medications while using this ointment?

Before using other medications or topical treatments, consult your healthcare provider to avoid potential interactions. They can provide guidance on safe use in conjunction with this ointment.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.