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Benazepril HCl 5 mg/0.1 mL Transdermal Gel (Vet)

Benazepril HCl 5 mg/0.1 mL Transdermal Gel (Vet) is a gel-like formulation, specifically designed for veterinary use. It is dispensed in syringes to ensure precise and controlled administration. This formulation is used for the targeted treatment of various disease states in animals. The transdermal delivery of the medication ensures accurate placement and optimal efficacy, providing effective treatment for the intended disease states.

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Benazepril Hydrochloride
Topical Gel (Veterinary)
6535764578bd5128b537b1b8
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Formula Information

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Benazepril HCl 5 mg/0.1 mL Transdermal Gel (Vet) is a specialized veterinary medication designed to treat a variety of disease states in animals. This formulation is dispensed in a gel-like form via syringes, allowing for precise and controlled administration. The transdermal delivery method ensures the medication is absorbed directly through the skin, providing targeted treatment and optimal efficacy.

Benazepril HCl is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking a substance in the body that causes blood vessels to tighten. As a result, the blood vessels relax and widen, making it easier for blood to flow, reducing the heart's workload and helping to lower blood pressure. This makes it particularly effective in treating conditions such as heart failure, hypertension, and certain types of kidney disease in animals.

The transdermal gel formulation is particularly beneficial for animals that are difficult to medicate orally. The gel is simply applied to a hairless area of the animal's body, typically the inner ear, where it is absorbed into the bloodstream. This provides a stress-free method of administration for both the animal and the owner or veterinary professional.

It's important to note that while Benazepril HCl Transdermal Gel is a powerful and effective medication, it should only be used under the guidance of a veterinary professional. The dosage and frequency of administration will depend on the specific condition being treated and the animal's response to the medication. Regular monitoring of the animal's condition and potential side effects is also crucial.

As with any medication, there may be potential side effects, including dizziness, weakness, or changes in kidney function. If you notice any adverse reactions in your animal, it's important to contact your veterinarian immediately.

If you have any questions about Benazepril HCl 5 mg/0.1 mL Transdermal Gel (Vet), or if you need further information about its use, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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Benazepril HCl is an angiotensin-converting enzyme (ACE) inhibitor used in veterinary medicine to treat conditions such as heart failure, hypertension, and kidney disease in animals. It works by blocking the action of a chemical in the body called angiotensin II, which causes blood vessels to constrict and promotes the release of another hormone that increases salt and water retention. By inhibiting these actions, Benazepril HCl helps to relax and widen blood vessels and reduce fluid build-up.

While Benazepril HCl is generally safe and effective when prescribed by a veterinarian, it can interact with other medications. These interactions can alter the way Benazepril HCl works and increase the risk of serious side effects.

One of the most significant drug interactions occurs with nonsteroidal anti-inflammatory drugs (NSAIDs). When Benazepril HCl is taken in combination with NSAIDs, it can reduce the antihypertensive effect of Benazepril HCl and increase the risk of kidney damage. Therefore, it is crucial to inform the veterinarian if your pet is taking any NSAIDs.

Benazepril HCl can also interact with other medications such as diuretics, vasodilators, and other antihypertensive drugs, leading to an increased risk of low blood pressure (hypotension). If your pet is taking any of these medications, dose adjustments may be necessary to prevent hypotension.

Other drugs that can interact with Benazepril HCl include potassium supplements or potassium-sparing diuretics, which can increase the risk of high potassium levels (hyperkalemia). If your pet is taking any of these medications, regular monitoring of potassium levels may be necessary.

It's important to note that this is not a complete list of all possible drug interactions. Therefore, it is crucial to inform the veterinarian of all the medications your pet is currently taking, including prescription drugs, over-the-counter medications, and dietary supplements.

Lastly, it's important to remember that every animal responds differently to medication. Therefore, it's crucial to monitor your pet closely while they are taking Benazepril HCl and report any unusual symptoms or behavior to the veterinarian immediately.

If you have any questions or concerns about the use of Benazepril HCl in your pet, please don't hesitate to reach out to us. We are here to help ensure the safe and effective use of this medication in your pet.

How Does it Work

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Benazepril HCl 5 mg/0.1 mL Transdermal Gel (Vet) is a specially formulated medication designed for veterinary use. It contains the active ingredient Benazepril Hydrochloride (HCl), a potent angiotensin-converting enzyme (ACE) inhibitor. This medication is typically used to treat conditions such as heart failure, hypertension, and certain types of kidney disease in animals.

The medication works by blocking the action of a compound in the body called angiotensin II. Angiotensin II causes blood vessels to constrict and promotes the release of another hormone, aldosterone, which causes salt and water retention. By inhibiting the production of angiotensin II, Benazepril HCl helps to relax and widen blood vessels, reduce fluid build-up, and decrease the workload on the heart.

The transdermal gel formulation allows for the medication to be absorbed through the skin and into the bloodstream. This method of administration can be particularly beneficial for animals that are difficult to medicate orally. The gel is dispensed in syringes for precise and controlled administration, ensuring accurate placement and optimal efficacy.

It's important to note that while Benazepril HCl can help manage the symptoms and progression of certain disease states, it is not a cure. Regular monitoring and adjustments to the treatment plan may be necessary based on the animal's response to the medication.

As with any medication, there may be potential side effects. These can include loss of appetite, vomiting, and lethargy. If you notice any adverse reactions in your pet, it's important to contact your veterinarian immediately.

Before starting your pet on Benazepril HCl 5 mg/0.1 mL Transdermal Gel (Vet), it's important to discuss your pet's medical history with your veterinarian, especially if your pet has kidney disease, liver disease, or a history of blood disorders. This medication should not be used in pregnant or lactating animals, or in animals with a known hypersensitivity to ACE inhibitors.

If you have any questions about this medication or its administration, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help ensure the best possible care for your pet.

Other Uses

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Apart from the primary indication of managing hypertension, this transdermal formulation of Benazepril HCL may also be employed in a variety of other uses within a veterinary context. The nature and vehicular choice of this formulation make it a prime candidate for applications requiring a speedy onset, local action, and controlled release of therapeutic agents.

Specifically, as a transdermal gel, this medication can be used in scenarios where oral administration is difficult or not possible. It also offers a solution where minimal stress is required, for instance, in managing feral or anxious animals. Long term, it plays a crucial role in managing diseases like chronic kidney disease where oral medications might stress the kidneys further, while a transdermal formulation bypasses first-pass metabolism, cutting the renal burden.

Furthermore, in heart disease, it functions to permit the heart to pump blood with less effort by blocking certain chemicals thereby resulting in less strain on the heart's muscles. In cases with protein-losing nephropathy and certain kidney diseases, it has been used off-label to manage proteinuria.

However, it's important to remember that off-label use should always be based on sound clinical judgment and adequate scientific rationale. Dose adjustments and diligent monitoring should be conducted by a licensed veterinarian when employing this product in any off-label capacity.

For any further questions on the potential uses of Benazepril HCl transdermal gel and its appropriateness in your specific veterinary setting, please reach out to us. We, at Bayview Pharmacy, are equipped to provide detailed counsel and assist in exploring possibilities for this formulation.

Frequently Asked Questions

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What is Benazepril HCl 5 mg/0.1 mL Transdermal Gel?

This is a gel-like medication prescribed by veterinarians for treating specific disease states in animals. It is compounded with an active ingredient, Benazepril Hydrochloride (HCl), at a concentration of 5 mg per 0.1 mL. It is delivered transdermally, meaning it passes through the skin.

Why is the medication dispensed in a syringe?

The use of a syringe allows for precise and controlled administration of the medication, ensuring the correct dosage is given. It also aids in the accurate placement of the gel on the animal, optimizing efficacy of the treatment.

What disease states can this medication treat?

Benazepril is primarily used to treat heart failure and kidney disease in pets. The specific conditions it can treat depend on the veterinarian’s diagnosis and the individual animal’s health requirements.

What species is this medication intended for?

This specific formulation is used for veterinary purposes. It is prescribed by a veterinarian based on the specific needs of individual pets, typically for cats and dogs.

How often should the medication be applied?

The frequency of administration depends on the specific instructions provided by the prescribing veterinarian. It's crucial to follow those instructions to ensure proper treatment.

What is the best way to apply this transdermal gel?

Transdermal gels are typically applied to an area of the skin where there is little to no hair, such as the inner ear or a shaved area, to ensure the medication is properly absorbed. Always wear gloves when applying to avoid self-exposure.

What are possible side effects of this medication?

While Benazepril is generally safe, it can have side effects in some animals. These may include loss of appetite, dizziness, and changes in behaviour. If you notice any adverse reactions in your pet, notify your veterinarian immediately.

Can I use this medication for other pets without a prescription?

No. This formulation should only be used for the animal for which it was prescribed, and in the manner directed by the veterinarian. Use in other animals could lead to adverse reactions or ineffective treatment.

How should I store this medication?

Store this medication at room temperature, away from light and moisture. Keep it out of the reach of children and pets when not in use. Do not use it beyond its expiration date.

What do I do if I miss a dose?

If you miss a dose, it's best to apply it as soon as you remember. However, if it's near the time for the next dose, skip the missed dose and return to your regular dosing schedule. Never double doses. If you have any concerns, consult your veterinarian.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.