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Baclofen 4%/Gabapentin 8%/Ketoprofen 6%/Lidocaine HCl 5% Topical Gel

This formulation is a compounded topical gel containing Baclofen 4%, Gabapentin 8%, Ketoprofen 6%, and Lidocaine HCl 5%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The combination of these active ingredients is designed to treat a variety of disease states. Baclofen is a muscle relaxer and an antispastic agent, Gabapentin is used to treat nerve pain and seizures, Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, swelling, and inflammation, and Lidocaine HCl is a local anesthetic that causes temporary numbness or loss of sensation in the area of application. This makes the formulation particularly effective for conditions such as neuropathic pain, musculoskeletal pain, inflammation, and localized pain conditions.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Baclofen 4%, Gabapentin 8%, Ketoprofen 6%, and Lidocaine HCl 5%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively for targeted treatment.

Baclofen is a muscle relaxant and antispasmodic agent used to relieve muscle symptoms caused by multiple sclerosis, including spasm, pain, and stiffness. Gabapentin is an anticonvulsant and nerve pain medication used to treat nerve pain caused by shingles (postherpetic neuralgia). It is also used to manage neuropathic pain, often in combination with other pain medications.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is used to treat mild to moderate pain, or inflammation caused by arthritis. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It is used on the skin to stop itching and pain from certain skin conditions (e.g., scrapes, minor burns, eczema, insect bites) and to treat minor discomfort and itching caused by hemorrhoids and certain other problems of the genital/anal area.

This combination of medications in a topical gel formulation allows for targeted treatment of various disease states, including neuropathic pain, muscle spasms, inflammation, and localized pain. The gel is applied directly to the affected area, providing relief at the source of pain and minimizing systemic side effects often associated with oral medications.

It is important to use this medication as directed by your healthcare provider. The amount of gel to be applied and the frequency of application will depend on the condition being treated and the individual patient's response to therapy. Always wash your hands after applying the gel unless your hands are the area being treated.

If you have any questions about this formulation or its use, please do not hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to assist you.

Drug Interactions

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This compounded formulation contains Baclofen, Gabapentin, Ketoprofen, and Lidocaine HCl. Each of these active ingredients has its own potential for drug interactions, which can be amplified when used in combination. It's important to note that this information is not exhaustive and other interactions may exist. Always consult with your healthcare provider or pharmacist for personalized advice.

Baclofen is a muscle relaxant and antispastic agent. It may interact with other central nervous system depressants like alcohol, benzodiazepines, opioids, and antihistamines, potentially leading to increased sedation and respiratory depression. Concurrent use with monoamine oxidase inhibitors (MAOIs) may result in hypotension.

Gabapentin, an anticonvulsant and nerve pain medication, may interact with antacids containing magnesium or aluminum, as they can reduce the absorption of gabapentin. It may also increase the effects of other drugs that cause sedation, including opioids, antihistamines, and alcohol.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), may interact with anticoagulants, antiplatelet drugs, and other NSAIDs, increasing the risk of bleeding. It may also interact with angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), or diuretics, potentially impairing kidney function. Concurrent use with lithium or methotrexate may increase their levels in the body.

Lidocaine HCl, a local anesthetic, has few systemic interactions due to its local application. However, it may interact with other local anesthetics or medications with similar metabolic pathways, potentially leading to increased systemic absorption and toxicity.

This formulation is designed to treat various disease states, including neuropathic pain, musculoskeletal pain, and inflammation. Baclofen and Gabapentin work to reduce nerve pain, Ketoprofen reduces inflammation and pain, and Lidocaine provides local numbing to the application area. The combined effect of these medications provides a targeted approach to pain and inflammation management.

It's crucial to inform your healthcare provider of all medications, supplements, and over-the-counter products you are currently taking to avoid potential interactions. If you have any questions or concerns about this formulation or potential interactions, please reach out to us at Bayview Pharmacy. We are here to help.

How Does it Work

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This formulation is a combination of four active ingredients: Baclofen, Gabapentin, Ketoprofen, and Lidocaine HCl, each playing a unique role in managing pain and inflammation. The formulation is designed to be applied topically, directly to the area of discomfort, allowing for targeted treatment.

Baclofen is a muscle relaxant and antispasmodic agent. It works by inhibiting the transmission of signals from the nerves to the muscles, thereby reducing muscle spasms and associated pain. This makes it particularly useful in conditions where muscle spasms contribute to pain, such as multiple sclerosis and spinal cord injuries.

Gabapentin is a medication primarily used to treat seizures and neuropathic pain. It works by reducing the abnormal electrical activity in the brain, which can lead to seizures, and by altering the way the nerves send signals to the brain about pain. This makes it effective in managing conditions like post-herpetic neuralgia and diabetic neuropathy.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing the production of prostaglandins, chemicals that cells produce in response to injury, leading to inflammation, pain, and fever. By reducing the levels of prostaglandins, Ketoprofen can help alleviate symptoms of conditions like arthritis and other musculoskeletal disorders.

Lidocaine HCl is a local anesthetic. It works by blocking the nerve signals in your body, causing a numbing effect. This makes it effective in providing temporary relief from pain and discomfort associated with skin irritations and minor cuts, burns, and abrasions.

The gel formulation allows for easy and precise application, and the pump mechanism ensures that the correct dose is dispensed each time. The gel is designed to be absorbed through the skin, delivering the active ingredients directly to the area of discomfort. This targeted approach can provide more effective relief than oral medications, which must be absorbed into the bloodstream and distributed throughout the body.

If you have any questions about this formulation, how it works, or how it can be used to manage specific conditions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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This topical gel formulation, containing Baclofen 4%, Gabapentin 8%, Ketoprofen 6%, and Lidocaine HCl 5%, is typically used as part of a multidisciplinary approach to managing various forms of pain, particularly neuropathic and musculoskeletal pain. Other disease states where this product may offer relief include radiculopathy, fibromyalgia, postherpetic neuralgia, and osteoarthritis, helping to reduce chronic inflammation, modulate nerve signal transmissions, and create a local anesthetic effect.

In addition to its more typical uses, this formulation may also be beneficial in other circumstances. For example, it may help with certain dermatological conditions where pain and inflammation are presenting symptoms. Such conditions may include dermatitis, psoriasis, or eczema, though it should be noted this is not its primary intended use and could only be considered in consultation with a healthcare professional specializing in dermatology.

The musculoskeletal pain relief properties of this formulation could also prove beneficial for those suffering from tendinitis or bursitis, common conditions amongst athletes or those who are physically active. Again, the application of this formulation for such uses should be discussed and planned under the supervision of a healthcare provider.

This formulation could potentially be utilized as an adjuvant therapy in cases involving cancer pain, especially bone cancer or metastasis, where neuropathic and inflammatory pain is common. However, significant care and consideration is required when prescribing for such use, given the complexity of associated variables, and it should only be done under the guidance of a physician specialized in oncology.

In all cases, this formulation should always be used following the precision dosing instruction dispensed through the product's pump mechanism. Careful monitoring of potential side effects such as irritation or allergic reaction should be maintained. Any unexpected or dramatic changes should be reported to a healthcare provider immediately.

While the above are potential other uses for this formulation, each individual's circumstances, overall health condition, other ongoing treatments, and the specific nature of their pain should be evaluated by a qualified healthcare provider when considering the most suitable therapeutic option.

If you have any questions about this formulation and its uses, we encourage you to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists are here to guide and support you through the decision-making process, ensuring you get the most out of the treatments available to you.

Frequently Asked Questions

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What is Baclofen 4%/Gabapentin 8%/Ketoprofen 6%/Lidocaine HCl 5% Topical Gel?

This is a compounded medication containing four active ingredients - Baclofen, Gabapentin, Ketoprofen, and Lidocaine. Each ingredient plays a strategic role in managing various types of pain, and all are delivered in a convenient gel form.

What are the main components of the compounded formulation?

The formulation is composed of Baclofen 4%, Gabapentin 8%, Ketoprofen 6%, and Lidocaine HCl 5% in topical gel format. Every element is included to provide relief from different types of pain and discomfort.

What are the indications for this particular compounded formulation?

The formulation is generally used for managing different types of pain, including neuropathic pain, muscle pain, inflammation, and skin irritation. As always the doctor will set the indication based on the individual patient's symptoms and history.

How does this compounded formulation work?

Each active ingredient delivers relief in different ways. Baclofen is a muscle relaxant; Gabapentin treats nerve pain; Ketoprofen is a nonsteroidal anti-inflammatory drug for reducing pain and inflammation, and Lidocaine is a local anesthetic. The gel is absorbed through the skin, targeting the area directly where the pain exists.

How is the Baclofen 4%/Gabapentin 8%/Ketoprofen 6%/Lidocaine HCl 5% Topical Gel applied?

This medication is released via a pump mechanism, which aids in the easy and accurate application on the skin. To use, you simply apply a small amount of the product to the skin in the area where pain or discomfort is experienced. Your doctor will provide instructions on how often to use the gel.

What is the texture of this compounded formulation?

The formulated medication is a semisolid consistent like a gel which facilitates effective application and absorption by the skin.

Can this formulation be used for any type of pain?

While it has broad application potential because of its multiple active ingredients, one should only use it under the discretion of a healthcare provider, who will assess its suitability based on the individual's situation and health condition.

Are there any known side effects of this compounded formulation?

Side effects can vary between individuals and depend on how one's body responds to the medication. However, common side effects may include skin irritation or redness at the application site. If you experience severe side effects, immediately consult your healthcare provider.

Are there any precautions or contraindications for this formulation?

Yes, usage of this gel should be avoided if you have hypersensitivity or allergic reaction to any of the active ingredients. It's always vital to inform your healthcare provider about any other medications you use, your current health conditions, or any allergic reactions you've had in the past.

Can I purchase this medication over the counter?

No, this formulation contains prescription medications and therefore requires a prescription from a healthcare provider.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.