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Formulas

Baclofen 2%/Ketoprofen 15%/Lidocaine HCl 5% Topical Gel

This formulation is a semisolid compound of Baclofen 2%, Ketoprofen 15%, and Lidocaine HCl 5% dispensed through a pump mechanism. The gel-like consistency allows for easy and precise application on the skin, ensuring targeted treatment and absorption of the active ingredients. The combination of these three active ingredients is designed to treat a variety of disease states.

Baclofen, a muscle relaxant and antispastic agent, is used to alleviate symptoms associated with muscle spasms and tightness. Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), is used to reduce inflammation and pain. Lidocaine HCl, a local anesthetic, provides temporary relief from pain and discomfort. Together, these ingredients work synergistically to provide relief from conditions such as musculoskeletal pain, neuropathic pain, and inflammation.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Baclofen 2%, Ketoprofen 15%, and Lidocaine HCl 5%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the targeted area for optimal therapeutic effect.

Baclofen is a muscle relaxant and antispasmodic agent that works by reducing muscle spasms, relieving pain, and improving muscle movement. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones causing inflammation and pain in the body. Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body, thereby reducing pain and discomfort.

This combination of active ingredients makes the formulation particularly effective in managing various disease states. It can be used to treat conditions such as musculoskeletal pain, neuropathic pain, and inflammation. The Baclofen component helps to alleviate muscle spasms and related discomfort, the Ketoprofen component targets inflammation and associated pain, and the Lidocaine HCl provides immediate, localized pain relief.

It is important to note that this formulation should be used as directed by a healthcare provider. The gel should be applied to the affected area in the quantity and frequency prescribed. Avoid contact with eyes, mouth, and other mucous membranes. If any adverse reactions occur, such as skin irritation or allergic reactions, discontinue use and consult your healthcare provider immediately.

As compounding pharmacists, we are able to customize this formulation to meet individual patient needs, adjusting the concentrations of the active ingredients as necessary. We can also modify the base used to create the gel, to accommodate patient preferences or allergies.

If you have any questions about this formulation, or if you are a prescriber interested in using this formulation for your patients, please do not hesitate to reach out to us. We are here to provide the information and support you need to ensure optimal treatment outcomes.

Drug Interactions

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This formulation combines Baclofen, Ketoprofen, and Lidocaine HCl in a topical gel. Each of these active ingredients has its own mechanism of action and potential for drug interactions.

Baclofen is a muscle relaxant and antispastic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to alleviate muscle spasms, pain, and stiffness. Baclofen may interact with other central nervous system depressants, including alcohol, antihistamines, sedatives, and opioids, potentially leading to increased sedation or respiratory depression.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is used to treat mild to moderate pain, or inflammation and stiffness caused by conditions such as arthritis. Ketoprofen may interact with other NSAIDs, blood thinners, corticosteroids, and certain antidepressants, potentially increasing the risk of gastrointestinal bleeding or ulcers.

Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body. It is used to reduce pain or discomfort caused by skin irritations. Lidocaine HCl may interact with other local anesthetics or medications that are similar in structure, potentially leading to increased risk of systemic toxicity.

As a topical gel, this formulation is designed to be applied directly to the skin, which can help to minimize systemic absorption and reduce the potential for drug interactions. However, it is still important to inform your healthcare provider of all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, to ensure this formulation is safe for you to use.

This formulation is intended to treat a variety of disease states. Baclofen can help to alleviate muscle spasms and stiffness associated with conditions such as multiple sclerosis or spinal cord injury. Ketoprofen can help to reduce pain and inflammation associated with conditions such as arthritis. Lidocaine HCl can help to alleviate pain or discomfort caused by skin irritations or minor procedures.

If you have any questions about this formulation or its potential interactions with other medications, please do not hesitate to reach out to us. We are here to help ensure that your treatment is both safe and effective.

How Does it Work

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The Baclofen 2%/Ketoprofen 15%/Lidocaine HCl 5% Topical Gel is a unique formulation that combines three active ingredients, each with its own therapeutic properties, to provide targeted relief from pain and inflammation. This formulation is dispensed as a semisolid gel through a pump mechanism, allowing for easy and precise application on the skin.

Baclofen, a muscle relaxant and antispastic agent, works by inhibiting the transmission of reflexes at the spinal level, which can help to alleviate muscle spasms, pain, and stiffness. This makes it particularly useful in conditions where spasticity or muscle tightness is a problem.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing the production of prostaglandins, substances in the body that cause inflammation and pain. By inhibiting their production, Ketoprofen can help to reduce inflammation and relieve pain.

Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body. When applied topically, it can help to numb the skin and underlying tissues, providing temporary relief from pain and discomfort.

When these three ingredients are combined in a topical gel, they can provide targeted relief from pain and inflammation. The gel formulation allows for the active ingredients to be absorbed directly through the skin, providing localized treatment to the area where it is applied. This can be particularly beneficial for conditions such as arthritis, sports injuries, or other conditions that cause pain and inflammation in specific areas of the body.

It's important to note that while this formulation can provide significant relief from pain and inflammation, it is not a cure for the underlying conditions causing these symptoms. It should be used as part of a comprehensive treatment plan, under the guidance of a healthcare provider.

If you have any questions about this formulation, or if you would like more information about how it can be used in your specific situation, please don't hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.

Other Uses

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Besides commonly being used to manage pain, inflammation, and muscle spasms, the Baclofen 2%/Ketoprofen 15%/Lidocaine HCl 5% topical gel formulation can also serve other uses. It is often utilized as a treatment for sports injuries due to its potent anti-inflammatory and analgesic properties conferred by its active ingredients. This formulation can provide targeted relief from acute sports-related injury pain, and it may also aid in the faster healing of soft tissue injuries.

This formulation may also be useful for managing post-herpetic neuralgia, a complication of shingles that presents as chronic pain in areas where the shingles rash occurred. The baclofen in the formula provides muscle relaxation which can be useful in conditions where muscle spasm or stiffness is present, such as in certain neurological disorders.

Furthermore, there could be potential utilization of this compound in palliative care scenarios, where managing complex pain syndromes is often challenging. The combination of the three active components could manage various aspects of pain perception, making it suitable for offering relief to patients with terminal illnesses. However, it is important to note that this would be considered an off-label use and should be approached with caution.

While this formulation shows promise for these uses, it’s critical that physicians properly evaluate each patient's individual needs and operating within the jurisdiction of prescribing law. Importantly, patients prescribed this formulation for off-label use should be monitored closely to ensure safety and efficacy.

If you have any further questions regarding Baclofen 2%/Ketoprofen 15%/Lidocaine HCl 5% topical gel, please feel free to reach out to us at Bayview Pharmacy. We are a team of knowledgeable compounding pharmacists, always ready to provide definitive information to both patients and prescribers.

Frequently Asked Questions

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What is the formula Baclofen 2%/Ketoprofen 15%/Lidocaine HCl 5% Topical Gel?

This is a compounded medication that combines Baclofen, Ketoprofen, and Lidocaine hydrochloride in a topical gel. These active ingredients are mixed in the concentrations of 2%, 15%, and 5% respectively.

How is this gel administered?

This gel is administered topically, meaning it is applied directly to the skin. The gel is dispensed using a pump mechanism for easy and precise application to the targeted area.

What is the consistency of this gel?

The gel has a semisolid formulation that aids in simple and accurate administration. Due to its consistency, the gel stays where it is applied rather than spreading or dripping, providing targeted treatment.

What are the active ingredients in this formulation?

The active ingredients in this formulation are Baclofen (a muscle relaxant and an antispastic agent), Ketoprofen (a nonsteroidal anti-inflammatory drug), and Lidocaine HCl (a local anesthetic).

What is the role of each active component in the formulation?

The Baclofen helps in relieving muscle spasms, the Ketoprofen aids in reducing pain and inflammation, and the Lidocaine HCl numbs the applied area to reduce pain sensation. The combined effect aims to provide comprehensive pain management.

How should this medication be stored?

Generally, you should store this medication at room temperature, away from moisture and direct light. For specific storage instructions, please refer to the label on the medication or consult your pharmacist.

What should I do if I miss a dose?

If you miss a dose of this medication, apply as soon as you remember. However, if it's near the time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

How often do I need to apply this gel?

The frequency of application can vary depending on your condition and medical advice. Therefore, it is important to adhere to your healthcare provider’s instructions.

Can I use this medication if I’m pregnant or breastfeeding?

Consult your healthcare provider before using this medication if you are pregnant, planning to get pregnant, or breastfeeding. They will make a decision based on your clinical condition.

Are there any known side effects?

The most common side effects are skin reactions where the medicine is applied, like redness or rash. If you experience any severe side effects or symptoms such as difficulty breathing or swelling, seek immediate medical attention.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.