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Formulas

Baclofen 2%/Ketoprofen 10%/Lidocaine HCl 5% Topical Gel

This formulation is a combination of Baclofen 2%, Ketoprofen 10%, and Lidocaine HCl 5% in a topical gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The Baclofen component is a muscle relaxant and antispasmodic agent, used to relieve symptoms such as muscle spasms, pain, and stiffness. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, swelling, and inflammation. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes.

This formulation is designed to treat a variety of disease states, including but not limited to, muscle spasms, chronic pain, inflammation, and localized pain conditions. It provides a targeted, localized treatment option, reducing the potential for systemic side effects.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Baclofen 2%, Ketoprofen 10%, and Lidocaine HCl 5%. It is designed to be dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the targeted area for optimal therapeutic effect.

Baclofen is a muscle relaxant and antispasmodic agent that works by reducing muscle spasms, relieving pain, and improving muscle movement. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones causing inflammation and pain in the body. Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body, thereby reducing pain and discomfort.

This unique combination of active ingredients makes this formulation particularly effective in managing various disease states. It can be used to treat conditions such as musculoskeletal pain, neuropathic pain, and inflammation. The topical application allows for targeted treatment, reducing systemic side effects often associated with oral medications.

Patients using this formulation should apply it as directed by their healthcare provider, typically to the affected area 3-4 times daily. It is important to wash hands before and after application and avoid contact with eyes, mouth, and open wounds. Side effects may include skin irritation at the application site. If these persist or worsen, contact your healthcare provider immediately.

Prescribers should consider this formulation for patients who have not responded to or cannot tolerate oral medications, or for those who prefer a topical treatment option. It is also an excellent choice for localized conditions where systemic treatment may not be necessary or desirable.

If you have any questions about this formulation, its use, or compounding in general, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to assist you.

Drug Interactions

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This compounded formulation contains Baclofen, Ketoprofen, and Lidocaine HCl, each of which may interact with other medications. It's important to inform your healthcare provider of all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.

Baclofen, a muscle relaxant and antispastic agent, may interact with other central nervous system depressants like alcohol, benzodiazepines, opioids, and antihistamines, potentially leading to increased sedation or respiratory depression. Concurrent use with monoamine oxidase inhibitors (MAOIs) may result in hypotension. Baclofen may also interact with antidiabetic agents, potentially requiring adjustment of the antidiabetic medication dosage.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), may interact with anticoagulants, increasing the risk of bleeding. It may also interact with other NSAIDs, corticosteroids, or alcohol, increasing the risk of gastrointestinal ulcers or bleeding. Ketoprofen may reduce the effectiveness of antihypertensive agents and diuretics. It may also interact with lithium, leading to increased lithium levels, and with methotrexate, increasing the toxicity of methotrexate.

Lidocaine HCl, a local anesthetic, may interact with other local anesthetics or medications structurally related to amide-type local anesthetics, potentially leading to additive systemic toxicity. It may also interact with antiarrhythmic drugs, potentially leading to additive myocardial depression.

This formulation is intended for topical use and is designed to treat a variety of conditions. Baclofen can help to relieve muscle spasms in conditions like multiple sclerosis, spinal cord injury, or cerebral palsy. Ketoprofen can help to reduce inflammation and pain in conditions like arthritis or acute injury. Lidocaine HCl can provide local anesthesia, numbing the skin and underlying tissues to reduce pain or discomfort.

It's important to use this medication as directed by your healthcare provider. Avoid applying it to broken or irritated skin, and avoid contact with eyes, nose, mouth, or other mucous membranes. Wash your hands thoroughly after applying the medication, unless your hands are the area being treated.

If you have any questions about this medication or its potential interactions, please don't hesitate to reach out to us. We're here to help ensure that your treatment is safe and effective.

How Does it Work

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The Baclofen 2%/Ketoprofen 10%/Lidocaine HCl 5% Topical Gel is a unique formulation that combines three active ingredients, each with a specific role in managing pain and inflammation. This formulation is designed to be applied topically, directly to the skin, where it can be absorbed to provide targeted relief.

Baclofen is a muscle relaxant and antispastic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to reduce muscle spasms, tightness, and pain. This makes it particularly useful in conditions where muscle spasms contribute to pain and discomfort.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing the production of prostaglandins, chemicals in the body that cause inflammation, pain, and fever. By reducing the levels of these chemicals, Ketoprofen can help to alleviate pain and reduce inflammation.

Lidocaine HCl is a local anesthetic. It works by blocking nerve signals in your body, which can help to numb the area and provide temporary relief from pain and discomfort. This makes it particularly useful in conditions where pain is a primary symptom.

The gel formulation allows for easy and precise application, and the pump mechanism ensures that the correct dose is dispensed each time. The gel is designed to be absorbed through the skin, allowing the active ingredients to work directly at the site of pain or inflammation. This can provide more targeted relief than oral medications, which must be absorbed through the digestive system and distributed throughout the body.

This formulation can be used to treat a variety of conditions, including but not limited to, muscle spasms, arthritis, and other conditions that cause pain and inflammation. It can also be used to manage pain following surgery or injury. As with any medication, it is important to use this formulation as directed by your healthcare provider.

If you have any questions about this formulation, how it works, or how to use it, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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Besides the primary use of this compounded formulation, Baclofen 2%/Ketoprofen 10%/Lidocaine HCl 5% Topical Gel also possesses potential benefits for a range of other conditions. The combination of active ingredients in this gel can provide relief in various disease states and conditions where inflammation and pain are prevalent.

For instance, Baclofen, being a muscle relaxant, in conjunction with Ketoprofen, a potent non-steroidal anti-inflammatory agent (NSAID), and Lidocaine, a local anesthetic, may be beneficial in alleviating pain associated with musculoskeletal conditions like osteoarthritis, tendonitis, bursitis, and strains/sprains. This compounded formulation might also be helpful in managing various neuropathic conditions, such as post-herpetic neuralgia, trigeminal neuralgia, and diabetic peripheral neuropathy among others.

The inherent muscle relaxant, anti-inflammatory, and anesthetic properties of this formulation might make it an adjunct treatment option in sports injuries and physical therapy, where immediate alleviation of pain and inflammation could speed up recovery and aid in progressive physiotherapy sessions. It may also be used as a part of multi-modal pain management in certain chronic pain conditions, including but not limited to fibromyalgia and complex regional pain syndrome (CRPS).

With careful counseling on appropriate application and usage, this compounded topical gel might also be considered in certain dermatologic conditions characterized by inflammation and/or pain. However, use in these conditions should be done after thorough risk evaluation and recommendation from a dermatologist, to avoid any potential adverse effects or unwanted drug reactions.

The prescribing physician should evaluate the potential benefits of using this formulation for off-label indications based on their clinical judgement, balancing the clinical need, potential risks, and available alternative treatments. As with any medication, this compound should be used as directed by a healthcare professional, ensuring the patient’s unique health history, current medications, potential drug interactions, and individual response are taken into account.

If there are any questions or additional information needed, feel free to reach out to us at Bayview Pharmacy. Our knowledgeable compounding pharmacists are always here to advise and ensure the safe and effective use of our compounded medications. Remember, our goal is to provide hands-on care for everyone's unique health needs.

Frequently Asked Questions

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What is the use of Baclofen 2%/Ketoprofen 10%/Lidocaine HCl 5% Topical Gel?

This compounded formulation is typically used to alleviate pain, inflammation, or muscle spasms by applying directly on the skin over the affected area. Because of its composition, it offers targeted relief with minimal systemic absorption.

Does this formulation come in a conventional packaging?

No, it is delivered through a sophisticated pump mechanism which furthers ease of use and precision in application.

What is the consistency of this topical gel?

This compound is a semisolid formulation that spreads evenly across the skin and absorbs quickly, thanks to its gel-like consistency.

How often should this gel be applied?

The frequency of application will depend on each individual's medical condition and the guidelines of their healthcare provider. Always follow their instructions to ensure optimal results.

Are there any known side effects associated with this gel?

Topical applications generally have fewer side effects than orally ingested medications, but individual tolerance can vary. If one encounters any adverse effects such as redness, itchiness, swelling, or any other skin irritation, they should cease usage and consult their healthcare provider immediately.

Can this gel be used in conjunction with other pain relieving methods?

Yes, but it is always recommended to consult your healthcare provider before incorporating any new treatments into your pain management routine.

Is this formulation suitable for all skin types?

The formulation is generally accepted by multiple skin types. However, as individual skin reactions can vary, any adverse reactions should immediately be reported to a healthcare provider.

Can this product be used by individuals of all ages?

While this formulation can often be used across a wide range of age groups, it's essential to consult with a healthcare provider to determine if it's appropriate, particularly in the case of children or older individuals.

Should this gel be applied directly on open wounds?

No, this gel should not be applied on open wounds or broken skin. It is intended for application on unbroken skin surfaces only.

Can this formulation cause any allergic reactions?

While it's unlikely, some individuals may be sensitive to some compounds. Any signs of an allergic reaction such as severe itching, blistering, or swelling should be addressed to your healthcare provider immediately.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.